• Journal of Magnetics
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• 제12권4호
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• pp.161-164
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• 2007

Constant temperature regulation of a hybrid heater which is composed of a temperature sensitive ferrite with low permeability and a Cu tube is investigated for hyperthermia. The temperature sensitive ferrite is inserted into a Cu tube and its length and diameter are 10 mm and 3 mm. Below B=0.05 T, the measured temperature and the calculated one increased with the ratio of $B^{1/2}$ and agreed well with each other. Above B=0.05 T, the measured temperatures maintained constantly almost $50^{\circ}C{\pm}1.5^{\circ}C$ because of the influence of Curie temperature of the temperature sensitive ferrite. This result shows that the hybrid heater is able to regulate the temperature constantly at the rate of $50^{\circ}C{\pm}1.5^{\circ}C$.

• 한국컴퓨터정보학회논문지
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• 제24권9호
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• pp.43-49
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• 2019

Today, with the development of the internet of things, wearable devices related to personal health care have become widespread. Various global information and communication technology companies are developing various wearable health devices, which can collect personal health information such as heart rate, steps, and calories, using sensors built into the device. However, since individual health data includes sensitive information, the collection of irrelevant health data can lead to personal privacy issue. Therefore, there is a growing need to develop technology for collecting sensitive health data from wearable health devices, while preserving privacy. In recent years, local differential privacy (LDP), which enables sensitive data collection while preserving privacy, has attracted much attention. In this paper, we develop a technology for collecting vast amount of health data from a smartwatch device, which is one of popular wearable health devices, using local difference privacy. Experiment results with real data show that the proposed method is able to effectively collect sensitive health data from smartwatch users, while preserving privacy.

• Journal of Korean Neurosurgical Society
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• 제50권5호
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• pp.426-433
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• 2011

Objective : The Histoculture Drug Response Assay (HDRA), which measures chemosensitivity using minced tumor tissue on drug-soaked gelfoam, has been expected to overcome the limitations of in vitro chemosensitivity test in part. We analyzed interim results of HDRA in malignant gliomas to see if the test can deserve further clinical trials. Methods : Thirty-three patients with malignant gliomas were operated and their tumor samples were examined for the chemosensitivity to 10 chosen drugs by HDRA. The most sensitive chemotherapy regimen among those pre-established was chosen based on the number of sensitive drugs or total inhibition rate (IR) of the regimen. The response was evaluated by 3 month magnetic resonance image. Results : Among 13 patients who underwent total resection of the tumor, 12 showed no evidence of disease and one patient revealed progression. The response rate in 20 patients with residual tumors was 55% (3 complete and 8 partial responses). HDRA sensitivity at the cut-off value of more than one sensitive drug in the applied regimen showed a sensitivity of 100%, specificity of 60% and predictability of 70%. Another cut-off value of >80% of total IR revealed a sensitivity of 100%, specificity of 69%, and predictability of 80%. For 12 newly diagnosed glioblastoma patients, median progression-free survival of the HDRA sensitive group was 21 months, while that of the non-sensitive group was 6 months ($p$=0.07). Conclusion : HDRA for malignant glioma was inferred as a feasible method to predict the chemotherapy response. We are encouraged to launch phase 2 clinical trial with chemosensitivity on HDRA.

• 한국동물위생학회지
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• 제24권4호
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• pp.347-352
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• 2001

This study was carried out to investigate the status of hoof diseases and to develope treatment method for cattle with hoof diseases during the period of January to December in 2000. Out of 435 heads, 34 heads(7.8%) had hoof diseases. In respect to season, incidence rate was higher in August to September than that of other seasons. The incidence rates of hoof rot, pododermatitis verrucosae, laminitis, other cases and trauma were 14 cases(41％), 10 cases (29%), 7 cases(21%), 2 cases(6%) and 1 case(3％), respectively. In respect to age and milk production, Incidence rate was higher in the cattle with high milk production. Incidence rate of hoof diseases on the hind-limbs was higher than that of the fore-limbs. E. coli(8 strains), Clostridium spp(8 strains), Staphylococcus spp(6 strains), Fusobacterium spp(6 strains), and Bacteroides spp(6 strains) were isolated from the hoof lesions. All isolates were sensitive to composite preparation made of mainly formalin with picric acid and phenol. (Treatment against each strains isolated was sensitive to composite preparation made out of the main constitutions of formalin with picric acid and phenol).

• 전산구조공학
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• 제17권4호
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• pp.23-28
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• 2004

• 보건행정학회지
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• 제26권1호
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• pp.4-11
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• 2016

Background: Hospital admissions for ambulatory care sensitive conditions (ACSCs), which are widely used as an indicator of poor access to primary care, can be used as an efficiency indicator of healthcare use in countries providing good access to health care. Korea, which has a national health insurance (NHI) system and a good supply of health care resources, is one such country. To quantify admission rates of ACSC and identify characteristics influencing variation in Korean health care institutions. Methods: By using NHI claims data, we computed the mean ACSC admission rate for all institutions with ACSC admissions. Results: The average ACSC admission rate for 4,461 institutions was 1.45%. Hospitals and clinics with inpatient beds showed larger variations in the ACSC admission rate (0%-87.9% and 0%-99.6%, respectively) and a higher coefficient of variation (7.96 and 2.29) than general/tertiary care hospitals (0%-19.1%, 0.85). The regression analysis results indicate that the ACSC admission rate was significantly higher for hospitals than for clinics (${\beta}=0.986$, p<0.05), and for private corporate institutions than public institutions (${\beta}=0.271$, p<0.05). Conclusion: Substantial variations in ACSC admission rates could suggest the potential problem of inefficient use of healthcare resources. Since hospitals and private corporate institutions tend to increase ACSC admission rates, future health policy should focus on these types of institutions.

• 환경위생공학
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• 제10권2호
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• pp.46-58
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• 1995

Acute toxicity of heavy metals( Mercury, Cadmium, Lead, Chromium and Copper ), Organophosphorus insecticides( EPN, 2, 4- D, and Parathion ), and other chemicals( Arsenic, Cyanide, and Phenol) to Daphnia magna, and Vibrio fischeri was analysed. Daphnia magna to most toxic chemicals was most sensitive among test organisms alld then Daphnia magna seems to be more useful in toxic test of water. Daphnia magna was more sensitive to heavy metals than insecticides and other chemicals. The sensitivity of Visrio JircAeri to heavy metals was not so different from that to insecticides and the sensitivity to other chemicals was low. Visrio JircAeri appears to be more sensitive to toxic chemicals than Photobacterium phosphoreum, which was compared as recorded values of P.phosphoreum. Toxic chemicals were classified as Group 1 which had a high $EC_{50}$ or $LC_{50}$ value and the low increase rate of toxicity according to the increase of concentration, Group 2 which had a high $EC_{50}$ or $LC_{50}$ value and the high increase rate of toxicity, Group 3 which had a low $EC_{50}$ or $LC_{50}$ value and the high increase rate of toxicity, and Group 4 which had a low $EC_{50}$ or $LC_{50}$ value and the low increase rate of toxicity. To Daphnia magna, Lead, Chromium EPN, and Parathion were included in Group 1 : Mercury and Copper in Group 2 : Arsonic and Cadmium in Group 3 : Cyanide, 2, 4-B, and Phenol in Group 4. To Visrio JircAeri, Lead, Chromiurl 2, 4- D, and Parathion were included in Group 1 : Merecury, Cadmium and Arsenic in Group 2 : Cyanide in Group 3 : EPN, Copper, and Phenol in Group 4.

• Journal of Korean Society for Atmospheric Environment
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• 제22권E2호
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• pp.89-98
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• 2006

Two tobacco cultivars (Nicotiana tabacum L.), Bel-B and Bel-W3, tolerant and sensitive to ozone, respectively, were grown in a greenhouse supplied with charcoal filtered air and exposed to 200 ppb ozone for 4 hr. Effects on chlorophyll fluorescence, net photosynthesis, and stomatal conductance are described. Quantum yield was calculated from chlorophyll fluorescence and the initial slope of the assimilation-light curve measured by the gas exchange method. Only the sensitive cultivar, Bel-W3, developed visual injury symptoms on up to 50% of the $5^{th}$ leaf. The maximum net photosynthetic rate of ozone-treated plants was reduced 40% compared to control plants immediately after ozone fumigation in the tolerant cultivar; however, photosynthesis recovered by 24 hr post fumigation and remained at the same level as control plants. On the other hand, ozone exposure reduced maximum net photosynthesis up to 50%, with no recovery, in the sensitive cultivar apparently causing permanent damage to the photosystem. Reductions in apparent quantum efficiency, calculated from the assimilation-light curve, differed between cultivars. Bel-B showed an immediate depression of 14% compared to controls, whereas, Bel-W3 showed a 27% decline. Electron transport rate (ETR), at saturating light intensity, decreased 58% and 80% immediately after ozone treatment in Bel-B and Bel-W3, respectively. Quantum yield decreased 28% and 36% in Bel-B and Bel-W3, respectively. It can be concluded that ozone caused a greater relative decrease in linear electron transport than maximum net photosynthesis, suggesting greater damage to PSII than the carbon reduction cycle.

• Corrosion Science and Technology
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• 제7권5호
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• pp.243-251
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• 2008

Magnesium alloys become popular research topic in last decade due to its light weight and relatively high strength-to-weight ratio in the energy aspiration age. Almost all structure materials are supposed to suspend stress. Magnesium is quite sensitive to corrosive environment, and also sensitive to environmental assisted cracking. However, so far we have the limited knowledge about the environmental sensitive cracking of magnesium alloys. The corrosion fatigue (CF) test was conducted. Many factors' effects, like grain size, texture, heat treatment, loading frequency, stress ratio, strain rate, chemical composition of environment, pH value, relative humidity were investigated. The results showed that all these factors had obvious influence on the crack initiation and propagation. Especially the dependence of CF life on pH value and frequency is quite different to the other traditional structural metallic materials. In order to interpret the results, the electrochemistry tests by polarization dynamic curve and electrochemical impedance spectroscopy were conducted with and without stress. The corrosion of magnesium alloys was also studied by in-situ observation in environmental scanning electron microscopy (ESEM). The corrosion rate changed with the wetting time during the initial corrosion process. The pre-charging of hydrogen caused crack initiated at $\beta$ phase, and with the increase of wetting time the crack propagated, implying that hydrogen produced by corrosion reaction participated in the process.

• Archives of Pharmacal Research
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• 제26권8호
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• pp.644-648
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• 2003

To investigate the feasibility of developing a new ondansetron transdermal system, the effects of vehicles and penetration enhancers on the in vitro permeation of ondansetron hydrochloride (OS) from a pressure-sensitive adhesive (PSA) matrices across dorsal hairless mouse skin were studied. Vehicles employed in this study consisted of various ratios of propylene glycol monocaprylate (PGMC)-diethylene glycol monoethyl ether (DGME) co-solvents and PGMC-propylene glycol (PG) co-solvents with 3% oleic acid. $Duro-Tak^\circledR$ 87-2100 and $Duro-Tak^\circledR$ 87-2196 were used as PSAs. The concentration of DGME in PGMC-DGME co-solvent system affected the release rate; as the concentration of DGME increased, the release rate decreased. The cumulative release amount of OS increased as the ratio of PSA to drug solution decreased. The permeation flux was also primarily affected by the amount of PSAs; as the amount decreased, the permeation flux increased. The overall fluxes from matrix formulations were significantly lower when compared to those obtained from solution formulations. The ratio of PG to PGMC did not affect permeation flux, while the lag time decreased significantly from $5.14\pm3.31 to 0.31\pm0.12$ h as the PG increased from 40% to 60%.