• Archives of Plastic Surgery
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• v.38 no.1
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• pp.117-120
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• 2011

Purpose: Carpal tunnel syndrome is the most common peripheral compressive neuropathy. Most cases are idiopathic, but rarely carpal tunnel syndrome can be associated with a ganglionic mass. We report our recently encountered experience of surgical treatment of carpal tunnel syndrome caused by a simple ganglionic mass. Methods: A 53-year-old man presented with chief complaints of numbness and hypoesthesia of his left palm, thumb, index finger, long finger, and ring finger of one and half month duration. Physical examination revealed positive Tinnel's sign without previous trauma, infection or any other events. Electromyography showed entrapment neuropathy of the median nerve. Magnetic resonance imaging (MRI) showed an approximately 2.0 cm-sized mass below the transverse carpal ligament. Upon surgical excision, a $1{\times}1.5cm^2$ mass attached to the perineurium of the median nerve and synovial sheath of the flexor digitorum superficialis and redness and hypertrophy of the median nerve were discovered. With surgical intervention, we completely removed the ganglionic mass and performed surgical release of the transverse carpal ligament. Results: The pathology report confirmed the mass to be a ganglion. The patient exhibited post-operative improvement of his symptoms and did not show any complications. Conclusion: We present a review of our experience with this rare case of carpal tunnel syndrome caused by a ganglionic mass and give a detailed follow-up on the patient treated by surgical exploration with carpal tunnel release.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6653-6656
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• 2013

Background: The single most common proto-oncogene change in human neoplasms is a point mutation in RAS genes. A wide range of variation in frequency of KRAS mutations has been seen in hematologic malignancies. Despite this, RAS roles in leukemogenesis remain unclear. The frequency of KRAS mutations in CML has been reported to be between zero an 10%. Many attempts have been done to develop an anti-RAS drug as a therapeutic target. Materials and Methods: This cross sectional study was performed in Mashhad University of Medical Sciences, Mashhad, Iran from 2010-2012. In 78 CML patients (diagnosed according to WHO 2008 criteria) in chronic or accelerated phases, KRAS mutations in codons 12 and 13 were analyzed using a modified PCR-restriction fragment length polymorphism (RFLP) method. Results: We did not detect any KRAS mutations in this study. Conclusions: KRAS mutations are overall rare in early phase CML and might be secondary events happening late in leukemogenesis cooperating with initial genetic lesions.

• Acta Via Serica
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• v.2 no.2
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• pp.7-27
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• 2017

The present study aims to do a documental study of the Mongol invasion and the fall of Baghdad (the capital of the Abbasid Caliphate) in 1258 CE. It is a case study on a document and two comments on it, which were originally recovered from the burial shroud of a person killed during $H{\ddot{u}}leg{\ddot{u}}^{\prime}s$ conquest of Baghdad. This document was later inserted by someone (possibly by one of its two commentators) in a section of a primary manuscript of Kitab al-Wara'a (written in 1147 CE). Then Osman ibn ${\dot{G}}{\bar{a}}nim$ al-Hiti and Ṭahir ibn '$Abd-All{\bar{a}}h$ ibn Ibrahim ibn Aḥmad, as commentators, wrote their comments about the document. Although these documents are in the form of fragmentary notes, they are rare primary sources that depict the events and the conditions of the siege, the conquest of Baghdad and the collapse of Abbasid Caliphate. This article, while providing images, revised texts, and translations of the documents, aims to introduce them and to explore the civil factors contributing to the fall of Baghdad.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.8 no.2
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• pp.226-232
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• 2005

Peptic ulcer disease complicated with gastric outlet obstruction is rare in children. Even though NSAIDs have been reported to cause various adverse events, they are still regarded as safe and, therefore, widely utilized in children. In the past, pediatric patients who were at risk of seizure due to high fever, were treated with dipyrone (Metamizole sodium) injection which inhibits cyclooxygenase-1 and inhibit prostaglandin, to weaken the gastro-duodenal defensive mechanism. A case of an infant with multiple esophagogatroduodenal ulcers and bleeding caused by NSAID complicated with gastric outlet obstruction is reported in this paper.

• Structural Engineering and Mechanics
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• v.67 no.1
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• pp.1-8
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• 2018

Shake table tests performed on five 1:3 reduced scale two story RC moment resisting frames having construction defects, have shown severe joint damageability in deficient RC frames, resulting in joint panels' cover spalling and core concrete crushing. Haunch retrofitting technique was adopted herein to upgrade the seismic resistance of the deficient RC frames. Additional four deficient RC frames were built and retrofitted with steel haunch; both axially stiffer and deformable with energy dissipation, fixed to the beam-column connections to reduce shear demand on joint panels. The as-built and retrofitted frames' seismic response parameters are calculated and compared to evaluate the viability of haunch retrofitting technique. The haunch retrofitting technique increased the lateral stiffness and strength of the structure, resulting in the increase of structure's overstrength. The retrofitting increased response modification factor R by 60% to 100%. Further, the input excitation PGA was correlated with the lateral roof displacement to derive structure response curve that have shown significant resistance of retrofitted models against input excitations. The technique can significantly enhance the seismic performance of deficient RC frames, particularly against the frequent and rare earthquake events, hence, promising for seismic risk mitigation.

• Journal of the Korean Operations Research and Management Science Society
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• v.37 no.3
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• pp.135-150
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• 2012

This paper presents a portfolio model for a long-term power generation mix problem. The proposed portfolio model evaluates generation mix by considering the tradeoffs between the expected cost for power generation and its variability. Unlike conventional portfolio models measuring variance, we introduce Conditional Value-at-Risk (CVaR) in designing the variability with aims to considering events that are enormously expensive but are rare such as nuclear power plant accidents. Further, we consider uncertainties associated with future electricity demand, fuel prices and their correlations, and capital costs for power plant investments. To obtain an objective generation by each energy source, we employ the sample average approximation method that approximates the stochastic objective function by taking the average of large sample values so that provides asymptotic convergence of optimal solutions. In addition, the method includes Monte Carlo simulation techniques in generating random samples from multivariate distributions. Applications of the proposed model and method are demonstrated through a case study of an electricity industry with nuclear, coal, oil (OCGT), and LNG (CCGT) in South Korea.

• The Korean Journal of Pain
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• v.9 no.1
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• pp.260-263
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• 1996

High spinal block is a rare complication during epidural block, but it may result in serious events. 56-year-old man with gall stones was scheduled for cholecystectomy under general anesthesia. After operation, lumbar epidural catheterization was done at $T_{8-9}$ interspace for postoperative pain control. At the recovery room, initial bolus drug (0.1% bupivacaine 10 ml containing fentanyl $100{\mu}g$) was administered via epidural catheter and observed carefully. 15 minutes later, hypotension and bradycardia ouccurred. Hartman' solution was administered rapidly and ephedrine 5 mg was injected. 30 minutes after drug administration, loss of consciousness and respiratory arrest developed. Tracheal intubation was done immediately. Cardiovascular and respiratory functions were monitored continuously. The location of intrathecal catheter was confirmed by cerebrospinal fluid (CSF) seen in syringe after aspiration of catheter. The patient recovered gradually and was placed in the ward 4 hours after drug administration, without any problems. He was discharged 1 week later in good health.

• Journal of Internet Computing and Services
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• v.1 no.1
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• pp.15-26
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• 2000

To efficiently manage data varying over time and process event driven transactions, some of the various database applications recently emerged require database systems supporting both a temporal data model and active rule processing. There has been much progress in independent research on temporal databases and active databases, but studies on databases which support both functions, have been rare. In this paper, an active temporal rule model supporting both active rule processing and temporal data model is presented with its rule expression language. This active temporal rule model contributes to the active function extension of the temporal database, and to establishing the concept of data access events which refer temporal attributes of data in active rules.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.1
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• pp.29.2-29.2
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• 2011

Although stellar flares have a long history of observations, there are few concrete understanding about underlying physical processes and meaningful correlations with other stellar properties. Most of previous observations dealt with only a small number of sample stars, and therefore not sufficient to support generalized statistical studies. Based on one-month long MMT time-series observations of the open cluster M37, we monitored light variations of nearly 2,500 M-dwarf stars and successfully identified 606 flare events from 422 stars. This is a rare attempt to estimate true flare rates and properties among many stars of the same age and mass group. For each flare, we considered both observational and physical parameters including flare shape, duration before and after the peak, baseline magnitude before and after the peak, peak magnitudes, total energy and peak energy, etc. We find significant correlations between some of key parameters over a wide range of energy ($Er=10^{32}{\sim}10^{36}ergs$). For instance, regardless of stellar luminosities, the energy power spectrum of flares can be approximated by a power law (${\beta}=0.83-0.97$). This suggests that flares follow similar physical mechanisms for atmospheric heating and cooling among these low-mass stars. From this MMT data set, we derived an average flaring rate of $0.019 hr^{-1}$ among flare stars and $0.003 hr^{-1}$ for all M-dwarf candidates. We will report the details of our analysis and discuss physical implications.

• Neonatal Medicine
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• v.28 no.2
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• pp.94-98
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• 2021

Neonatal diabetes mellitus (NDM) is a rare disease that occurs at less than 6 months of age and is presumably caused by a mutation in the gene that affects pancreatic beta-cell function. Approximately 80% of NDM cases reveal a known genetic mutation, and mutations in potassium inwardly rectifying channel subfamily J member 11 (KCNJ11) and ABCC8 affecting the pancreatic beta-cell adenosine triphosphate-sensitive potassium channel may be treated with oral sulfonylurea. Early recognition of mutations in KCNJ11 and ABCC8 is important because early administration of sulfonylurea can not only control blood glucose levels but also improve neurodevelopmental outcomes. In the present study, we report a case of NDM that initially presented as diabetic ketoacidosis at the age of 1 month, accompanied by seizures during hospitalization. After confirmation of the KCNJ11 gene mutation (c.989A>C), we started administering oral sulfonylurea (glimepiride) at the age of 2 months. After gradually increasing the dosage of glimepiride, insulin was discontinued at the age of 3 months. To date, the infant's blood glucose levels have been well controlled without significant hypoglycemic events. No further episodes of seizures have occurred, and his developmental status is favorable.