• Asian-Australasian Journal of Animal Sciences
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• 제19권12호
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• pp.1696-1701
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• 2006

A random regression model was applied for the first time for the analysis of test day records and to study the genetic persistency of first lactation milk yield of Indian Murrah buffaloes. Wilmink's Function was chosen to describe the shape of lactation curves. Heritabilities of test day milk yield varied from 0.33 to 0.58 in different test days. The highest heritability was found in the initial test day ($5^{th}$ day) milk yield. Genetic correlations among test day milk yields were higher in the initial test day milk yield and decreased when the test day interval was increased. The magnitude of genetic correlations between test day and 305 day milk yield varied from 0.25 to 0.99. The genetic persistencies of first lactation milk yield were estimated based on daily breeding values using two methods. $P_1$ is the genetic persistency estimated as a summation of the deviation of estimated daily breeding value on days to attain peak yield from each day after days to attain peak yield to different lactation days. $P_2$ is the genetic persistency estimated as the additional genetic yield (gained or lost) from days to attain peak yield to estimated breeding value on different lactation days relative to an average buffalo having the same yield on days to attain peak yield. The mean genetic persistency on 90, 120, 180, 240, 278 and 305 days in milk was estimated as -4.23, -21.67, -101.67, -229.57, -330.06 and -388.64, respectively by $P_1$, whereas by $P_2$ on same days in milk were estimated as -3.96 (-0.32 kg), -23.94 (-0.87 kg), -112.81 (-1.96 kg), -245.83 (-2.81 kg), -350.04 (-3.28 kg) and -407.58 (-3.40 kg) respectively. Higher magnitude of rank correlations indicated that the ranking of buffaloes based on their genetic persistency in both methods were similar for evaluation of genetic persistency of buffaloes. Based on the estimated range of genetic persistency three types of genetic persistency were identified. Genetic correlations among genetic persistency in different days in milk and between genetic persistencies on the same day in milk were very high. The genetic correlations between genetic persistency for different days in milk and estimated breeding value for 305 DIM was increased from 90 DIM to 180 DIM, and highest around 240 DIM which indicates a minimum of 240 days as an optimum first lactation length might be required for genetic evaluation of Indian Murrah buffaloes.

• 임상간호연구
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• 제18권2호
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• pp.284-295
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• 2012

Purpose: This study was done to clarify effects of bispectral index monitoring sedative administration, compared to MOAA/S (Modified Observer's Assessment of Alertness and Sedation), on conscious sedation, physiological stability and recovery time for patients undergoing endoscopic submucosal dissection. Methods: Participants In this study were patients who underwent endoscopic submucosal dissection because of early gastric cancer. Participants were assigned randomly to an experimental group receiving sedatives based on bispectral index monitoring or to a control group with the MOAA/S instrument. Movements, belching, memory, pain, discomfort, physiological stability (MBP, PR, $SpO_2$), and recovery time were measured during the treatment and recovery. Data were analyzed using Spearman partial correlation coefficient analysis, Mixed model and Wilcoxon rank sum test to determine differences in the parameters. Results: There were no statistically significant differences between the two groups for conscious sedation(movement, belching, memory, pain, or discomfort), physiological stability and recovery time. Conclusion: The results of this study indicate that no differences were found between the two types of monitoring. Thus, use of a bispectral index monitor in clinical practice enabling medical staff to readily assess the conscious sedation of for these patients is expected to be increasingly used as an objective assessment tool for conscious sedation for patient safety.

• 지역연구
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• 제33권4호
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• pp.3-17
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• 2017

본 연구는 Oxford Economics에서 제공하는 Global Cities Forecast 자료(2013)를 이용하여 한국의 7대 광역시를 포함한 전 세계 주요도시의 경쟁력지수 및 분배지수를 산출하고 그 종합순위를 정리하였다. 도시경쟁력지수는 규모지표, 비율지표, 성장률지표 등 총 18개 경제관련 지표를 선택하였고, 분배지수로서 지니계수를 이용하였다. 경쟁력지수와 지니계수 간의 관계를 분석하기 위하여 LOGIT 회귀모형을 이용하여 분석하였으며 추정결과 소득불평등(지니계수) 증가는 5년 시차로 볼 때 도시경쟁력지수 또한 경제성장률 변화에 음(-)의 영향을 미치고 있으며 통계적으로 유의하였다. 지니계수가 높을수록 도시경쟁력에 부정적으로 영향을 미친다는 추정결과에 따라 도시경쟁력지수에 분배지수를 포함시켜 총 19개 지표로 세계주요 도시 및 국내 7대 광역시의 글로벌 도시경쟁력 위상을 정리하였다. 2012년 실질가치 기준으로 계산된 서울의 도시 종합경쟁력 순위는 2010년 세계 59위, 2015년 세계 74위, 2030년에는 세계 185위로 급격히 하락하는 것으로 나타나고 있으며 나머지 6대 광역시의 종합경쟁력지수도 모두 하락하는 것으로 나타났다. 도시경쟁력 하락은 장기적으로 국가경쟁력 하락을 의미하므로 도시경쟁력 확보를 위한 문제점 진단과 전략적 방안의 강구가 절실히 요구된다.

• Radiation Oncology Journal
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• 제37권3호
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• pp.166-175
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• 2019

Purpose: This study aimed to investigate neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors in patients with locally advanced non-small cell lung cancer (NSCLC) who received concurrent chemoradiotherapy (CCRT). Materials and Methods: We retrospectively analyzed 66 patients with locally advanced NSCLC treated with definitive CCRT. Among these patients, 95% received paclitaxel/carboplatin or docetaxel/cisplatin. The median radiation dose was 66 Gy in 33 fractions. The NLR and PLR before/after CCRT were evaluated. The maximally selected log-rank test was used to obtain the cutoff values related to the overall survival (OS). Results: Patients with high post-CCRT NLR (>3.12) showed worse OS, locoregional progression-free survival (LRPFS), and distant metastasis-free survival (DMFS) than those with low NLR (2-year OS: 25.8% vs. 68.2%, p < 0.001; 2-year LRPFS: 12.9% vs. 33.8%, p = 0.010; 2-year DMFS: 22.6% vs. 38.2%, p = 0.030). Patients with high post-CCRT PLR (>141) showed worse OS and LRPFS than those with low PLR (2-year OS: 37.5% vs. 71.1%, p = 0.004; 2-year LRPFS: 16.5% vs. 40.3%, p = 0.040). Patients with high NLR change (>1.61) showed worse OS and LRPFS than those with low NLR change (2-year OS: 26.0% vs. 59.0%, p < 0.001; 2-year LRPFS: 6.8% vs. 31.8%, p = 0.004). The planning target volume (hazard ration [HR] = 2.05, p = 0.028) and NLR change (HR = 3.17, p = 0.025) were the significant factors for OS in the multivariate analysis. Conclusion: NLR change after CCRT was associated with poor prognosis of survival in patients with locally advanced NSCLC. An elevated NLR after CCRT might be an indicator of an increased treatment failure risk.

• 한국산업보건학회지
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• 제26권3호
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• pp.324-333
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• 2016

Objectives: We aimed to compare the sampling performance of different flow-based impactor samplers for collecting fungal spores and bacteria and to explore the association of the level of bioaerosols with activity patterns of occupants in daycare center settings. Methods: For comparison of sampling performance, two different flow-based samplers (greater than 100 L/min or not) were selected; a low flow-based sampler (one-stage Andersen sampler) and two high flow-based samplers (DUO SAS SUPER 360 sampler, BUCK bio-culture sampler). We collected airborne mold and bacteria in 30 daycare centers with various levels of contaminated air. Three repeat samplings per each sampler were performed. Mold and bacteria were grown for 96 hours at $25{\pm}1^{\circ}C$ and 48 hours at $35{\pm}1^{\circ}C$, respectively. The Andersen and SAS samplers were used for investigating the association between the level of bioaerosols and the activity patterns of occupants in daycares. Particular matters 10($PM_{10}$), temperature, and relative humidity were monitored as well. Samplings were carried out with one-hour interval from 9 to 5 O'clock. For statistical comparisons, Kruskal-Wallis test, Wilcoxon's signed rank test, and multiple regression analysis were carried out. Results: The airborne level of molds by the low flow-based sampler were significantly higher than that of high flow-based samplers (indoor, P=0.037; outdoor, P=0.041). However, no statistical difference was observed in the airborne level of bacteria by each sampler. Also the level of bioaerosols varied by the time, particularly with different activity patterns in daycare centers. The higher level of mold and bacteria were observed in play time in indoor. Similarly, the concentrations of $PM_{10}$ were significantly associated with the level of bioaerosols (P<0.05). Conclusions: Our findings indicate that the flow rate of sampler, rather than total air volume, could be able to affect the results of sampling. Also, the level of airborne mold and bacteria vary behavior patterns of occupants in indoor of daycare settings. Therefore, different samplers with other flow rate may be selected for mold or bacteria sampling, and activity patterns should be considered for bioaerosol sampling as well.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권6호
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• pp.521-530
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• 2020

Purpose: Malnutrition is a common feature in critically ill children. Enteral nutrition (EN) is the main strategy to nutritionally support critical ill children, but its use can be hindered by the development of intolerance. The study aimed to assess the effectiveness and safety of amoxicillin/clavulanate (A/C) to treat EN intolerance. Methods: We retrospectively evaluated patients admitted to the pediatric intensive care unit from October 2018 to October 2019. We conducted a case-control study: in the first 6 months (October 2018-April 2019) we implemented the nutritional protocol of our Institution with no drug, whereas in the second half (May 2019-October 2019) we employed A/C for 1 week at a dose of 10 mg/kg twice daily. Results: Twelve cases were compared with 12 controls. At the final evaluation, enteral intake was significantly higher than that at baseline in the cases (from 2.1±3.7 to 66.1±27.4% of requirement, p=0.0001 by Wilcoxon matched-pairs signed rank test) but not in the controls (from 0.2±0.8 to 6.0±14.1% of the requirement, p=NS). Final gastric residual volume at the end of the observation was significantly lower in the cases than in the controls (p=0.0398). The drug was well tolerated as shown by the similar safety outcomes in both cases and controls. Conclusion: Malnutrition exposes critically ill children to several complications that affect the severity of disease course, length of stay, and mortality; all may be prevented by early EN. The development of intolerance to EN could be addressed with the use of A/C. Future prospective clinical trials are needed to confirm these conclusions.

• 한국정보과학회논문지:소프트웨어및응용
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• 제34권1호
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• pp.40-51
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• 2007

학업성취도 향상을 위해 정규 수업 이외에도 과외, 학원수강, 교육방송 시청 등 다양한 교육이 이루어지고 있다. 본 논문에서는 방학 중 학습방법과 생활습관이 학업성취도 변화에 미치는 영향을 분석하기 위한 데이타 마이닝 접근법을 제안한다. 우선, 학업성취도에 영향을 미치는 방학중의 학습방법과 생활습관에 대한 다양한 요소를 도출한다. 다음으로, 마이닝 기법 중 의사결정트리와 연관 규칙을 사용하기 위한 데이타 변환 및 분석 방법을 제안한다. 마지막으로, 설문조사를 통해 수집한 현실의 구체적 데이터에서 의사결정트리를 생성하고 연관 규칙을 추출하는 방법을 제안한다. 중학생들에 대한 설문조사를 분석한 결과, 의사결정트리의 경우 네 가지 의미있는 결과를 도출하였다. 첫째, 상위권 학생들의 경우 학원수강이 성적을 향상시키는 것으로 나타났다. 둘째, 대부분 학생들의 경우 인터넷 학습사이트 이용은 성적을 하락시키는 것으로 나타났다. 셋째, 성적 변화에 큰 영향을 미칠 것으로 예상했던 과외는 실제로 큰 영향을 미치지 못하는 것으로 나타났다. 넷째, 다양한 학습방법의 병행은 오히려 성적 하락의 요인이 되는 것으로 파악되었다. 다음으로, 연관 규칙 추출 결과, 방학 중 활동 사이에는 특이한 규칙이 없는 것으로 나타났다. 본 논문에서 제시한 데이타 마이닝 접근법 및 결과는 학생들의 방학 중 생활 지도나 학습 계획 수립에 많은 도움이 될 수 있다고 사료된다.

• 정보관리연구
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• 제31권4호
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• pp.50-70
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• 2000

인터넷으로 접근할 수 정보의 형태가 텍스트는 물론 이미지나 사운드까지 포함되면서 다양한 웹 이미지 검색엔진들이 개발되고 있다. 그러나 이 검색엔진들은 검색 특성과 효율성 면에서 상당한 차이를 보이고 있다. 이에 본 연구에서는 현재 개발된 이미지정보를 탐색하는 검색엔진들의 유형을 살펴보고 이들의 특성과 성능을 비교 평가하여 이용자로 하여금 정보요구에 적합한 이미지 검색엔진을 선택할 수 있도록 하는데 그 목적이 있다. 본 연구의 비교대상 검색엔진으로는 현재 가장 널리 쓰이고 있는 AV Photo Finder, Lycos MultiMedia, Amazing Picture Machina Image Surfer, WebSeek, Ditto를 선정하였다. 먼저 문헌연구를 통해 이미지 검색엔진의 평가기준을 마련하였다. 그리고 마련된 기준에 따라 각 검색엔진들의 데이터베이스 및 색인 방법, 검색 기능, 출력 형태, 이용자 인터페이스를 조사하였고 검색성능을 평가하기 위해 상대적 재현율과 정확률을 측정하였다. 그 결과 AV Photo Finder의 정확률이 가장 높았고 Ditto와 WebSeek의 정확률은 비교적 높은 편이었다. 그리고 Lycos MultiMedia와 Image Surfer의 정확률 값이 그 뒤를 이었으며 Amazing Picture Machine의 정확율이 가장 낮았다.

• Journal of Radiation Protection and Research
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• 제39권4호
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• pp.206-212
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• 2014

진폐요양기관에 대한 실태조사를 실시하여 진폐요양환자에게 사용되는 흉부 CT촬영 선량이 국내외 진단 참고 준위 내에서 사용되는지 알아보았다. 진폐요양기관은 27개 중에서 운용자 콘솔 컴퓨터에서 환자 피폭선량(dose length product, $mGy^*cm$, 이하 DLP) 확인이 가능한 2-Detector 이상 설치된 17개 기관을 대상으로 하였다. 연구대상기관을 직접 연구자가 방문하여 위치잡이촬영, 조영제 사용전,후촬영 및 총 DLP 값을 각각 확인하였다. 또한, 장치의 기본 항목, 위치잡이촬영 조건, 본촬영(scanning) 조건 및 영상 획득 조건을 확인하였다. 흉부 CT촬영에서 확인된 총 DLP 값, 조영제주입전촬영 DLP 값의 상향서열 3/4 순위에 해당하는 DLP 값을 구하였다. SPSS ver. 19.0을 사용하여 전체 영상과 폐야영상 간에 조영제주입전촬영 DLP 값의 비교는 비모수 검정(Wilcoxon signed rank test)을 실시하였다. 전체영상보다 폐야영상을 얻을 때 20.2%의 유의한 DLP 값 감소를 보였다(707.2 vs. 555.9, p<0.001). 흉부 CT촬영에서 확인된 총 DLP 값의 상향서열 3/4 순위(third quartile)의 DLP 값은 $1036.1mGy{\cdot}cm$였다. 흉부 CT촬영의 조영제 주입전촬영에서 확인된 DLP 값의 상향서열 3/4 순위의 DLP 값은 $504.1mGy{\cdot}cm$였다. 진폐요양환자의 흉부 CT촬영에 사용하는 선량은 국내외 진단 참고 준위와 큰 차이를 보이지 않았다.

• Safety and Health at Work
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• 제6권1호
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• pp.25-29
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• 2015

Background: Shift work has been associated with occupational stress in health providers and in those working in some industrial companies. The association is not well established in the law enforcement workforce. Our objective was to examine the association between shift work and police work-related stress. Methods: The number of stressful events that occurred in the previous month and year was obtained using the Spielberger Police Stress Survey among 365 police officers aged 27-66 years. Work hours were derived from daily payroll records. A dominant shift (day, afternoon, or night) was defined for each participant as the shift with the largest percentage of total time a participant worked (starting time from 4:00 AM to 11:59 AM, from 12 PM to 7:59 PM, and from 8:00 PM to 3:59 AM for day, afternoon, and night shift, respectively) in the previous month or year. Analysis of variance and covariance were used to examine the number of total and subscale (administrative/professional pressure, physical/psychological danger, or organizational support) stressful events across the shift. Results: During the previous month and year, officers working the afternoon and night shifts reported more stressful events than day shift officers for total stress, administrative/professional pressure, and physical/psychological danger (p < 0.05). These differences were independent of age, sex, race/ethnicity, and police rank. The frequency of these stressful events did not differ significantly between officers working the afternoon and night shifts. Conclusion: Non-day shift workers may be exposed to more stressful events in this cohort. Interventions to reduce or manage police stress that are tailored by shift may be considered.