• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5587-5591
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• 2012

Objective: This study was performed to evaluated the efficacy and safety of continuous infusional paclitaxel and 5-Fu as first-line chemotherapy in patients with advanced esophageal squamous cell cancer (ESCC). Methods: A total of 22 patients with advanced esophageal squamous cell cancer with no indications for surgery and radiation therapy, or recurrent patients were enrolled from October 2008 to November 2010. All were treated with PTX 20 $mg/m^2$ was administered through a 16 hours continuous intravenous infusion on days 1 to 3, 8 and 9. DDP 3.75 $mg/m^2$ was given on days 1 to 4 and 8 to 11, continuous infusional 5-FU over 24-hours on days 1 to 5 and 8 to 12 at a dose of 375 $mg/m^2$, and folacin 60 mg orally synchronized with 5-Fu. The treatment was repeated every 21 days for at least two cycles. Results: 22 cases of all enrolled patients could be evaluated for the effect of treatment: 2 cases were CR, 9 cases PR, 5 cases SD and 2 cases PD, giving an overall response rate of 68.2%(15/22). The median time to progression was 7.0 months. The adverse reactions related to chemotherapy were tolerable; the most common toxic effects were marrow depression, alopecia, and fatigue. Conclusion: Low-dose continuous infusional PTX over 16-hours and 5-fu over 24-hours is a promising regimen with good tolerability in treating patients with advanced esophageal squamous cell cancer.

• 대한기계학회논문집A
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• 제26권2호
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• pp.387-398
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• 2002

The impact response and damage of CLAS panel was investigated experimentally. The facesheet material used was RO4003 woven-glass hydrocarbon/ceramic and the core material was Nomex honeycomb with a cell size of 3.2mm and a density of 96 kg/㎥. The shield plane used was RO4003 and 2024-T3 aluminum. Static indentation and impact test was conducted to characterize the type and extent of the damage observed in two CLAS panels, and the performance of antenna used in a wireless LAN system. Correlation of peak contact force, residual indentation and the delamination area shows impact damage of the panel with an aluminum shield plane is larger than that of the panel with RO4003 shield plane, although the former is more penetration resistant. The damage was observed by naked eye, ultrasonic inspection and cross sectioning. The shape and size of delamination was estimated by ultrasonic inspection, and the area of delamination linearly increases as impact energy increases. The performance of impact damaged antenna was estimated by measuring return loss and radiation pattern. It was revealed that the performance of antenna was related to the impact damage and there was a threshold that the performance of antenna fell as impact energy level changed. The threshold was between the impact energies of 1.5J and 1.75J.

• 한국전기전자재료학회논문지
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• 제23권9호
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• pp.708-713
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• 2010

In this research a ring light was developed so that a partial shadowless shooting for the patient's affected area at the medical treatment room and surgical operation room using high luminance light emitting diode (LED) for which attention is being paid as new lighting parts for medical purpose. LED which was applied to the development used high luminance three color LED for full color for which various color materialization and the adjustment of radiation intensity are possible and we can get white light in order to emphasize the delicate expression for generic tone of shooting object, strong highlight, simple shadow and three dimensional effect at the time of close-up shadowless shooting of the affected area. And at the time of design of ring light, the characteristics of LED and the loss of light at the time of penetrating light diffusion PC were considered so that intensity of illumination for over 150 lx can be obtained. The result of measurement of the intensity of illumination of the ring light that was developed revealed that maximum intensity of illumination of 225.7 lx was obtained, while smoke index was measured to be maximum 78 Ra in the case of Red(50%) Green(100%) and Blue LED(60%). We could confirm that response speed was also very fast as 1.72 ms.

• 한국의학물리학회지:의학물리
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• 제2권2호
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• pp.129-139
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• 1991

중성자 선원에 의한 되튕긴 양성자의 궤적을 PN-3 검출기를 이용하여 화학적 부식방식으로 검출하는 방법에 대해 논의해 보았다. 또한 PN-3 의 부식 및 검출특성을 부식된 궤적지름과 여러 변수들로 표시하여 보았다. 본 연구를 통해 고체 비적 검출기에 검출된 입자를 분석하기 위해 입자의 전하, 에너지, 질량과 궤적 부식 비율 결정 및 궤적 구조 형성 과정 사이의 관계식에 대한 자세한 정보를 얻을 수 있었다. 또한 하전입자를 보다 정확하게 검출하기 위해 입자의 종류 및 에너지에 대한 부식 조건을 변화시키면서 이에 대응하는 최적의 부식조건을 경험적으로 찾아내었다. 아울러 기대되는 기술 저변 확대 효과로는 고분자플라스틱 검출기를 이용한 저준위 중성자 측정기술의 축적 및 개발을 통해 원자력발전소, 비파괴검사기관 및 의료기관 동 방사선 동위원소 취급기관의 중성자 선량측정계로의 유용한 응용 가능성이 예상된다.

• Journal of Korean Neurosurgical Society
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• 제55권5호
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• pp.255-260
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• 2014

Objective : The purpose of this study was to compare the radiological and neurological outcomes between two atlantoaxial fusion method for atlantoaxial stabilization; C1 lateral mass-C2 pedicle screws (screw-rod constructs, SRC) versus C1-2 transarticular screws (TAS). Methods : Forty-one patients in whom atlantoaxial instability was treated with atlantoaxial fixation by SRC group (27 patients, from March 2005 to May 2011) or TAS group (14 patients, from May 2000 to December 2005) were retrospectively reviewed. Numeric rating scale (NRS) for pain assessment, Oswestry disability index (ODI), and Frankel grade were also checked for neurological outcome. In radiologic outcome assessment, proper screw position and fusion rate were checked. Perioperative parameters such as blood loss during operation, operation time, and radiation exposure time were also reviewed. Results : The improvement of NRS and ODI were not different between both groups significantly. Good to excellent response in Frankel grade is shown similarly in both groups. Proper screw position and fusion rate were also observed similarly between two groups. Total bleeding amount during operation is lesser in SRC group than TAS group, but not significantly (p=0.06). Operation time and X-ray exposure time were shorter in SRC group than in TAS group (all p<0.001). Conclusion : Both TAS and SRC could be selected as safe and effective treatment options for C1-2 instability. But the perioperative result, which is technical demanding and X-ray exposure might be expected better in SRC group compared to TAS group.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4861-4864
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• 2014

Background: The Ewing's sarcoma family is a group of small round cell tumors which accounts for 10-15% of all primary bone neoplasms. The aim of this study was to evaluate the survival of Ewing's sarcoma patients in our province and to determine of influencing factors. Materials and Methods: All patients with documented Ewing's sarcoma/primitive neuroectodermal tumor(PNET) family pathology were enrolled in this study during a period of eight years. For all of them local and systemic therapy were carried out. Overall and event free survival and prognostic factors were evaluated. Results: Thirty two patients were enrolled in the study. The median age was 17.5 years. Twenty (65.2%) were male and 9 (28.1%) were aged 14 years or less. Mean disease free survival was 26.8 (95%CI; 13.8-39.9) months and five year disease free survival was 26%. Mean overall survival was 38.7 months (95%CI; 25.9-50.6) and median overall survival was 24 months. Five year overall survival was 25%. From the variables evaluated, only presence of metastatic disease at presentation (p value=0. 028) and complete response (p value =0. 006) had significant relations to overall survival. Conclusions: Survival of Ewing's sarcoma in our province is disappointing. It seems to be mostly due to less effective treatment. Administration of adequate chemotherapy dosage, resection of tumor with negative margins and precise assessment of irradiation volume may prove helpful.

• 한국인터넷방송통신학회논문지
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• 제17권6호
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• pp.89-95
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• 2017

UFMC(Universal Filtered Multi Carrier)는 OFDM(Orthogonal Frequency Division Modulation)보다 비동기적인 상황과 ICI(Inter Carrier Interference)에 강한 장점으로 5G 무선통신 시스템의 후보로 주목 받고 있다. UFMC 시스템에서는 부밴드 마다 필터링을 하기 때문에 필터의 성능이 매우 중요하다. 기존 UFMC 시스템의 필터는 대역외 방사가 작다는 장점으로 필터를 사용해 왔다. 그러나 이 필터는 부밴드 내의 왜곡이 있고 스커트 특성이 좋지 않다. 따라서 부밴드 내의 왜곡을 줄일 수 있으며 스커트 특성이 뛰어난 새로운 형태의 UFMC 필터에 대한 연구가 필요하다. 본 논문은 UFMC 시스템에서 필터의 주파수 응답 형태가 미치는 영향을 분석하고 기존 시스템에서 사용되어 왔던 Dolph-ChebyShev 필터를 대체할 필터로 Wavelet 기반의 필터를 제시한다. 모의실험을 통해 wavelet 필터가 기존의 필터 보다 다중 경로 페이딩 채널에서 더 나은 BER(Bit Error Rate)성능을 보임을 확인 하였다.

• 천문학회보
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• 제39권2호
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• pp.113.1-113.1
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• 2014

We propose a three-year Key Science Program (KSP) consisting of VLBI monitoring observations and single dish (SD) rapid response observations (RRO). The VLBI monitoring observations are comprised of ten 24-hr observations per year (every month) of about 30 gamma-ray brigt active galactic nuclei (AGNs) with Korea VLBI Network (KVN) at 22, 43, 86, and 129 GHz. The SD RROs may consist of twelve 7-hr observations per source (every week for 3 months after triggering) of gamma-ray flaring sources with two KVN SD telescopes at 22, 43, and 86 GHz in dual polarization. We expect one or two sources per year for the SD RROs. Gamma-ray flares of AGNs are known to be occured in innermost regions of relativistic jets which radiate in whole ranges of electromagnetic spectra due to synchrotron radiation, syschrotron self absorption, inverse-compton scttering, doppler boosting etc. Possible explanations of the gamma-ray flares in AGNs are a) shocks-in-jets propagating within jet flow and b) bending of the whole jets. For both cases, we should expect changes in polarization, luminosity, particle distribution, and structures of jets at mas-scale. The multifrequency simultaneous VLBI/SD observations with KVN are the best tool for detecting such changes correlated with gamma-ray flares. This KSP proposal aims to answer the fundamental questions about the basic nature of the flares of AGNs.

• 한국해양공학회지
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• 제32권1호
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• pp.1-8
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• 2018

In order to analyze the response of the offshore structure numerically, the linear potential theory is generally applied for simplicity, and only the radiation damping is considered among various damping forces. Therefore, the results of a numerical simulation can be different from the motion of the structure in a real environment. To reduce the differences between the simulation results and experimental results, the viscous damping, which affects the motion of the structure, is also taken into account. The appropriate damping model is essential for the numerical simulation in order to obtain precise responses of the offshore structure. In this study, various damping models such as linear or quadratic damping and the nonlinear drag force from numerous slender bodies were used to simulate the free decay motion of the platform, and its characteristics were confirmed. The optimized damping model was found by comparing the simulation results to the experimental results. The hydrodynamic forces and wave exciting forces of the structure were obtained using WAMIT, and the free decay test was simulated using OrcaFlex. A free decay test of the scale model was performed by KRISO.

• 치과방사선
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• 제19권1호
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• pp.39-48
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• 1989

Six to eight-month-old female albino rats were used as experimental animals. As an irradiation equipment, a Co-60 was used. The experimental animals were divided to; 6 of the control group, 12 of the 500cGy single irradiation group, 12 of the 1000cGy fractionated irradiation group, and 12 of the 1500cGy fractionated irradiation group. From the first week to the forth, 3 rats were picked from each group every week to be sacrificed and fixed with formalin. Those rats were observed by means of H-E stain after being taken radiograph and decalcified. The analysis of radiographic findings and light microscopic findings gives results as follows: 1. The delay of dental eruption rate was found in every group which underwent the irradiation experiment. Dentin niche, osteodentin, and dentin island were formed in the parts which were damaged by the irradiation. 2. The longer the observation period was, the more deposit of osteodentin and dentin island was formed. 3. In the single irradiation group, the damage effect was in proportion to the increase of radiation dose, whereas the damage was much less in the fractionated group receiving the same dose. 4. The 500cGy single irradiation group got temporary repairable damage, while the 1000cGy single irradiation group got considerable damage and showed much slower eruption rate than the 500cGy single irradiation group. The basal portion of the 1500cGy single irradiation group, whose growth was arrested, was destroyed. 5. The fractionated group were irradiated 500cGy everyweek. Repair was visible during the interval periods. The damage was accumulated as irradiation repeated, but degree of damage was lower than that of the 1000cGy and 1500cGy single irradiation group.