• 제목/요약/키워드: radiation resistance

검색결과 423건 처리시간 0.026초

온실재배 토마토의 증산모델 개발 및 검증 (Transpiration Modelling and Verification in Greenhouse Tomato)

  • 이변우
    • 생물환경조절학회지
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    • 제6권3호
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    • pp.205-215
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    • 1997
  • 본 연구에서는 온실 재배 토마토 군락의 열수지에 근거한 증산모델을 구성하고 실험을 통하여 모텔에 필요한 계수의 추정과 모질의 검증을 수행하였다. 온실의 일사략과 엽-대기수증기압차(LVPD)를 매개변수로 하는 기공확산저항 추정식을 구성하여 기공작산저항 실측 자료를 이용하여 추정식의 계수를 추정하였다. 이 추정식으로 기공확산저항 변이의 80% 이상을 설명할 수 있었으며 추정식에 이용하지 않았던 독립 자료를 이용하여 검정한 결과 추정정도가 높아 증산예측 모델의 구성식으로 이용될 수 있는 것으로 판단되었다. 반투과성 매질의 복사 흡수이론을 적용한 Stanghellini의 식을 다소 변형하여 모델의 군락 순복사 추정식으로 사용하였으며 이 추정식에 의하여 계산된 순복사량은 실측치와 잘 일치하였다. 계수 추정에 사용하지 않았던 독립 자료를 이용하여 순복사 및 기공확산저항 추정식으로 구성된 증산예측 모델의 군락온도 및 증산예측 정도를 검증하였다. 모델에 의하여 계산된 군락 온도, 순간 증산속도 및 일 총 증산량은 실측치와 잘 일치하여 본 연구에서 작성된 증산 예측 모델은 온실 재배 토마토의 환경제어, 관개제어 등에 실용적으로 활용될 수 있을 것으로 판단되었다.

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FBW7 Upregulation Enhances Cisplatin Cytotoxicity in Non-small Cell Lung Cancer Cells

  • Yu, Hao-Gang;Wei, Wei;Xia, Li-Hong;Han, Wei-Li;Zhao, Peng;Wu, Sheng-Jun;Li, Wei-Dong;Chen, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권11호
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    • pp.6321-6326
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    • 2013
  • Introduction: Lung cancer is extremely harmful to human health and has one of the highest worldwide incidences of all malignant tumors. Approximately 80% of lung cancers are classified as non-small cell lung cancers (NSCLCs). Cisplatin-based multidrug chemotherapy regimen is standard for such lesions, but drug resistance is an increasing problem. F-box/WD repeat-containing protein 7 (FBW7) is a member of the F-box protein family that regulates cell cycle progression, and cell growth and differentiation. FBW7 also functions as a tumor suppressor. Methods: We used cell viability assays, Western blotting, and immunofluorescence combined with siRNA interference or plasmid transfection to investigate the underlying mechanism of cisplatin resistance in NSCLC cells. Results: We found that FBW7 upregulation significantly increased cisplatin chemosensitivity and that cells expressing low levels of FBW7, such as NCI-H1299 cells, have a mesenchymal phenotype. Furthermore, siRNA-mediated silencing or plasmid-mediated upregulation of FBW7 resulted in altered epithelial-mesenchymal transition (EMT) patterns in NSCLC cells. These data support a role for FBW7 in regulating the EMT in NSCLC cells. Conclusion: FBW7 is a potential drug target for combating drug resistance and regulating the EMT in NSCLC cells.

Study on Proton Radiation Resistance of 410 Martensitic Stainless Steels under 3 MeV Proton Irradiation

  • Lee, Jae-Woong;Surabhi, S.;Yoon, Soon-Gil;Ryu, Ho Jin;Park, Byong-Guk;Cho, Yeon-Ho;Jang, Yong-Tae;Jeong, Jong-Ryul
    • Journal of Magnetics
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    • 제21권2호
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    • pp.183-186
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    • 2016
  • In this study, we report on an investigation of proton radiation resistance of 410 martensitic stainless steels under 3 MeV proton with the doses ranging from $1.0{\times}10^{15}$ to $1.0{\times}10^{17}p/cm^2$ at the temperature 623 K. Vibrating sample magnetometer (VSM) and X-ray diffractometer (XRD) were used to study the variation of magnetic properties and structural damages by virtue of proton irradiation, respectively. VSM and XRD analysis revealed that the 410 martensitic stainless steels showed proton radiation resistance up to $10^{17}p/cm^2$. Proton energy degradation and flux attenuations in 410 stainless steels as a function of penetration depth were calculated by using Stopping and Range of Ions in Matter (SRIM) code. It suggested that the 410 stainless steels have the radiation resistance up to $5.2{\times}10^{-3}$ dpa which corresponds to neutron irradiation of $3.5{\times}10^{18}n/cm^2$. These results could be used to predict the maintenance period of SUS410 stainless steels in fission power plants.

한강물로부터 분리된 방사선 내성 세균들의 계통학적 다양성 및 UV 내성 분석 (Phylogenetic diversity and UV resistance analysis of radiation-resistant bacteria isolated from the water in Han River)

  • 이재진;주은선;이도희;정희영;김명겸
    • 미생물학회지
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    • 제52권1호
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    • pp.65-73
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    • 2016
  • 이 논문은 서울 한강물에서 분리한 방사선 내성 세균군집과 분리된 신종 세균의 UV 내성 특성에 관한 내용이다. 세균은 R2A agar와 1/10 R2A agar를 사용하여 3 kGy가 조사된 한강물에서 분리되었다. 그 결과 방사선에 내성을 가지는 것으로 추측되는 균주를 60주 분리하였고, 본 연구 분석 자료로 사용하였다. 16S rRNA 유전자 염기서열 분석을 통해 분리균주 60개의 계통수를 파악한 결과, 3개의 문(4개의 속)이 확인되었고, Deinococcus-Thermus (Deinococcus)가 61.7%, Firmicutes(Exiguobacterium)는 15%, Bacteroidetes (Hymenobacter, Spirosoma)는 23.4%의 비중을 나타냈다. 분리균주 중 29개 균주가 Deinococcus, Hymenobacter, Spirosoma에 속하는 신종 또는 다른 신속으로 분류될 가능성을 보였으며, 앞으로 추가적인 신종 실험이 진행될 예정이다. 그리고 신종 예상균주를 9개 선정하여 UV 내성 실험을 진행한 결과, 9개 균주 모두 D. radiodurans $R1^T$ 균주 만큼 높은 UV 내성을 가지는 것으로 나타났다. 또한 분리된 Firmicutes (Exiguobacterium) 균주는 아직까지 방사선 내성 연구 보고가 되어 있지 않아서 추가적인 방사선 내성 연구가 필요하다.

평면 배열형 사각형 음향 트랜스듀서의 상호 방사 임피던스 연구 (An Investigation of Mutual Radiation Impedance in a Plane Array Acoustic Transducer)

  • 이종길;서인창
    • 한국음향학회지
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    • 제14권6호
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    • pp.21-26
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    • 1995
  • 본 연구에서는 사각형 음향 진동체가 무한 배플에 고정되어 있을때 진동체 상호간의 방사 임피던스의 양을 예측하기 위하여 적분식을 유도하고 이를 수치해석 하였다. 상호 방사 임피던스를 방사 저항 및 방사 리액턴스로 분리하여 계산하고 이를 ka및 kd의 함수로 출력 하였다. 방사 저항은 ka값의 증가에 따라 요동을 하면서 감소 하였다. 방사 리액턴스는 ka값의 증가에 따라 감소 하였다. 또한 상호 방사 임피던스는 ka의 값이 클수록 방사 임피던스의 양은 요동을 하면서 감소 하였다. 그러나 ka가6, 13및 19의 근처에서는 오히려 상호 임피던스의 영향이 거의 없음을 볼 수 있었고 진동체 상호간의 거리가 멀어질수록 임피던스의 영향이 현저히 감소함을 보았다. 또한ka의 값이 클수록 진동체 상호간의 배치에서 45도의 경우에 상호 간섭이 오히려 감소하였다.

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Ultraviolet-B radiation sensitivities in rice plant: cyclobutane pyrimidine dimer photolyase activities and gene mutations

  • Hidema, Jun;Kumagai, Tadashi
    • 한국식물생명공학회:학술대회논문집
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    • 한국식물생명공학회 2004년도 생명공학 실용화를 위한 비젼
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    • pp.29-34
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    • 2004
  • Reduction in stratospheric ozone layer increases the amount of ultraviolet-B radiation (UVB: 280-320 nm) that reaches the earth ’ s surface. UVB radiationcan damage plants, resulting in decrease in growth and productivity. UVB-augmentation studies have indicated that the sensitivity to UVB radiation in plants varies among the species and cultivars. However. there are no definitive answers for the mechanisms of UVB-resistance in higher plants and for bioengineering design and development of UVB-tolerant plants. We have been studying physiological and biochemical aspects of the effects of UVB radiation on growth and yield of rice COryza sativa LJ. aiming to clarify the mechanism of resistance to UVB radiationin rice. At this meeting. weintroduce our research as followed: (1) supplementary UVB radiation has inhibitory effects on the growth. yield and grain development of rice; (2) UVB sensitivity of rice varies widely among cultivars; (3) among Japanese rice cultivars. Sasanishiki. a leading variety in northeast Japan. is more resistant to UVB. while Norin 1. a progenitor of Sasanishiki. is less resistant; (4)UV-sensitive Norin 1 cultivar is deficient in photorepair of UVB-induced cyclobutane pyrimidine dimer (CPD). and this deficiency results from one amino acid residue alteration of CPD photolyase. These results suggest that spontaneously occurring mutation in CPD photolyase gene could lead to difference in UVB sensitivity in rice. and that CPD photolyase might be a useful target for improving UVB-sensitivity in rice by selective breeding or bioengineering of UVB-tolerant rice.

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트리억제제가 첨가된 LDPE의 방사선 조사에 따른 절연특성 변화 (Variation of Insulation Characteristics due to ${\gamma}$-ray Irradiation on LDPE Contained Treeing Inhibitors)

  • 류부형
    • 한국안전학회지
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    • 제27권2호
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    • pp.13-19
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    • 2012
  • The effectiveness of treeing resistance in low density polyethylene containing azocompounds were investigated under radiation environments. 4-(4-nitrophenylazo)-1-naphthol and 4-(4-nitrophenylazo) resorcinol were selected for treeing inhibitors. LDPE containing the additives were crosslinked with dicumyl peroxide, irradiated by $Co^{60}$ ${\gamma}$-ray in the presence of air at room temperature. Treeing inception voltage, AC breakdown strength measurements were carried out for electrical insulation characteristics, thermoluminescence and gel contents were analyzed as various irradiation doses also. LDPE with treeing inhibitors showed much better insulation characteristics than pure LDPE. It is interpreted that molecular structures, polar groups and the type of radicals connected on the benzene ring of the additives affected electrical characteristics. From the results, 4-(4-nitrophenylazo) resorcinol was the most effective upon the best treeing and radiation resistance.

복사열전달을 고려한 고층아파트 연속난방 열공급제어 시뮬레이션 (Simulation of Heat Supply Control of Continuous Heating System of Multistoried Apartment in Consideration of Radiation Heat Transfer)

  • 최영돈;홍진관;윤종호;이남호
    • 설비공학논문집
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    • 제6권2호
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    • pp.78-92
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    • 1994
  • Thermal performance of pipe network of continuous heating system controlled by thermostat and flow control valve was simulated in consideration of radiation heat transfer and solved by linear analysis method. Thermal performance of real apartment building with radiant floor heating system was simulated by equivalence heat resistance-capacity method. This method enables to simulate the unsteady variation of temperature or each element of building. Heat transfer characteristics of each element were also investigated.

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부채仙人掌( Opuntia lanceolata Haw. )의 葉牀莖方位에 따른 光合成樣式의 變化에 관한 硏究 (A Study on the Change of Photosynthetic Patterns by the Cladode Orientation of Opuntia lanceolata Haw.)

  • Chang, Nam-Kee;Chang-Duck Jin;Young-Soo Kim
    • The Korean Journal of Ecology
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    • 제7권3호
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    • pp.99-108
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    • 1983
  • Diurnal acid fluctuation, stomatal resistance, and solar radiation with regard to the cladode orientation were investigated in Opuntia lanceolata Haw. growing at WPeolryeong-ri, Hallim-eup, Chejudo, Korea. Diurnal changes of titratable acidity showed the typical CAM pattern in all investigated cladodes. Water tissue in the cladode had the same pattern of acid fluctuation as mesophyll tissue. Stomatal resistance was low during the night, increased rapidly to be a peak right after sunrise and decreased again thereafter. The southern side of the cladode showed higher stomatal resistance than the northern side during the day time. It suggests that the stomata of the northern side opens under diffuse radiation. The amount of solar radiation varied depending upon the cladode orientation. It is thought that C4 acids move inter and intra mesophyll tissues in the cladode through the unknown pathways. RuBP carboxyulase activity in the cladode was very high at 14:00, but was not significant at 01:00. PEP-carboxylase had high activities both at 14:00 and at 01:00. The results of this study showed the possibility that O. lanceolata Haw. had the C3, C4 and CAM photosynthetic patterns under the environmental conditions at Weolryeong-ri.

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