• Journal of Biosystems Engineering
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• 제21권4호
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• pp.429-435
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• 1996

A wind tunnel consisting of two air flow conditioners with polycarbonate pipes, a plant growth room, a suction fan and fan controller, and fluorescent lamps, was designed to investigate the interactions between the growth of plug seedlings under artificial light and their Physical environments. Light transmissivities in the plant growth room based on the photosynthetic photon flux density and photosynthetically active radiation was appeared to be 96.3% and 96.8%, respectively. Measurement showed a uniformity in the vertical profiles of air current speed at the middle and rear regions of plug trays in wind tunnel. This result indicated that the development of a wind tunnel based on the design criteria of the American Society of Mechanical Engineers was adequate. Air current speed inside the plug stand was significantly decreased due to the resistance by the leaves of plug seedlings and boundary layer developed over and below the plug stand. Driving force to facilitate the diffusion of gas inside the plug stand might be regarded as extremely low. Aerodynamic characteristics above the plug stand under artificial light were investigated. As the air current speed increased, zero plane displacement decreased but roughness length and frictional velocity increased. Zero plane displacement linearly increased with the average height of plug seedlings. The wind tunnel developed in this study would be useful to investigate the effects of air current speed on the microclimate over and inside the plug stand and to collect basic data for a large-scale plug production under artificial light in a semi-closed ecosystem.

• BMB Reports
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• 제41권3호
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• pp.230-235
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• 2008

LRP15 is a novel gene cloned from lymphocytic cells, and its function is still unknown. Bioinformatic data showed that LRP15 might be regulated by DNA methylation and had an important role in DNA repair. In this study, we investigate whether the expression of LRP15 is regulated by DNA methylation, and whether overexpression of LRP15 increases efficiency of DNA repair of UV-induced DNA damage in HeLa cells. The results showed (1) the promoter of LRP15 was hypermethylated in HeLa cells, resulting a silence of its expression. Gene expression was restored by a demethylating agent, 5-aza-2'-deoxycytidine, but not by a histone deacetylase inhibitor, trichostatin A; (2) overexpression of LRP15 inhibited HeLa cell proliferation, and the numbers of cells in the G2/M phase of the cell cycle in cells transfected with LRP15 increased about 10% compared with controls; (3) cyclin B1 level was much lower in cells overexpressing LRP15 than in control cells; and (4) after exposure to UV radiation, the LRP15-positive cells showed shorter comet tails compared with the LRP15-negative cells. From these results we conclude that the expression of LRP15 is controlled by methylation in its promoter in HeLa cells, and LRP15 confers resistance to UV damage and accelerates the DNA repair rate.

• 대한한의학회지
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• 제26권2호
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• pp.1-12
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• 2005

Objectives: Malignant gliomas are often treated with cisplatin (cis-diamminedichloroplatinum(II), CDDP) and radiation but results remain unsatisfactory. Since malignant glioma displays moderate resistance to conventional therapy, a new treatment modality is needed to improve the outcome of patients with these tumors. The aim of this study was to investigate the effects of the combined use of Jongjihwan(JJH) and cisplatin(CDDP) on cultured malignant glioma cells, A172. Methodss & Results: The combined use of cisplatin and Jeongjihwan had synergistic effects on Al72 cells during 24 hr-incubation, This treatment resulted in a decrease of cell viability, Which was revealed as apoptosis Characterized by activation of caspase-3 protease as well as cleavage of poly ADP-ribose polymerase (PARP) with change of mitochondria membrane potential transition. The expression of members of the Bcl-2 protein family was modulated during co-treatment with Jeongjihwan and cisplatin. Activation of caspase-3 and mitochondrial alterations were central to co-treatment with Jeongjihwan and cisplatin-induced apoptosis. Conclusions: We conclude that co-treatment with Jeongjihwan and cisplatin-induced activation of the mitochondrial pathway enables cell death. Also, we suggest the combined theory of JJH and cisplatin could be a useful method for glioblastoma.

• 방사성폐기물학회지
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• 제10권3호
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• pp.209-218
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• 2012

현재 한국원자력연구원에서는 국내에 축적된 사용후핵연료 문제를 해결하기 위해서 건식재처리공정(pyroprocess)을 개발 중에 있다. 건식재처리 공정에서는 상당량의 고준위 염폐기물이 발생되며, 이는 곧 세라믹 결합제로 고화된다. 고화된 세라믹 폐기물은 안전한 금속 처분용기에 밀폐된 후, 인간생활환경과 격리될 예정이다. 본문에서는 고준위 세라믹폐기물을 처분하기 위한 처분용기의 개발에 관한 전반적인 내용을 다루고 있으며, 특히 처분용기의 설계 요건, 용기의 구성, 용기의 제작, 용기의 부식저항성, 방사선 차폐, 구조적 안전성 등에 대해 논의하고자 한다. 완성된 처분용기는 오랜 기간 동안 방사성 핵종의 누출이 없이 열적, 기계적, 화학적, 생물학적 공격에도 안전한 것을 목적으로 한다.

• 한국농공학회논문집
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• 제46권4호
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• pp.39-46
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• 2004

This experiment was carried out to study on the effect of surface coating on thermal insulation of farm structures to improve thermal resistance and reflective effect of solar radiation. Nine different types of experimental specimen were compared in the temperature variations of inside and outside; A, B, C, D. E and F types are box container and G, H and I types are drum container. The size of these containers is $1,500{\times}2,000{\times}2,500$ mm and ${\varphi}$ $280{\times}330$ mm, respectively. Specimen of 3-type box(A, B, C) is galvanized steel sheet of thickness 0.45 mm. D, E and F types are sandwich panel of the thickness 50 mm inserted with urethane, glass wool and polystyrene form, respectively. G, H and I types are paint pot using in general. The surface of A. D, E, F and I types didn't any treatment, B, C and G types were treated with thermal insulation coating on the outside surface(B, G) or the inside and outside surface(C). And H type was treated with water paint coating on the only outside surface. In general, the experimental results showed the following tendencies; In case of A, B and C types. it was found that the thermal insulation effect of types coated with thermal insulation coating was improved remarkably than that of no treatment. And the thermal insulation effect between steel sheet and sandwich panel type was nearly similar There was not a significant difference of thermal insulation effect between thermal insulation coating and water paint coating. In time of drum container filled with rough rice, The difference of heat transfer tendency and temperature variation among surface treatments was nearly similar that of box types of galvanized steel sheet. And there was time lag about 6 hours between the temperature of middle part of rice and that of inside or outside surface.

• The Korean Journal of Pain
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• 제21권1호
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• pp.57-61
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• 2008

Background: Shoulder joint injection is currently performed under fluoroscopic or computed tomography scan guidance. We performed this study to determine if an ultrasound guided shoulder joint injection through rotator cuff interval would have clinical usefulness. Methods: A total of 17 volunteers [12 women, 5 men; mean age 28 yr (23-32 yr)] received shoulder joint injection under multilinear ultrasound (5-10 MHz). Volunteers were positioned supinely on a table with their arm in a neutral position. The anterior shoulder region of the patient was sterilized using povidone iodine. A 24 gauge needle was introduced and directly visualized in real time as it passed obliquely from the skin surface to the inferior space of the biceps tendon. If there was little or no resistance to the injection, a contrast media (omnipaque) was injected and checked fluoroscopically. Results: Ultrasound guided shoulder joint injection through rotator cuff interval was successful in all cases. The average time taken for the procedure was $27.5{\pm}16.5sec$. The vertical distance from skin to the inferior space of the biceps tendon was $1.6{\pm}0.4cm$ and the distance of needle from the skin to the inferior space of biceps tendon was $2.8{\pm}0.6cm$. The procedure was well tolerated by all volunteers. Conclusions: Ultrasound guided shoulder joint injection through rotator cuff interval is an effective, rapid, and easy-to-perform injection technique. Ultrasound guided injection enables exact needle placement and avoids the use of both ionizing radiation and iodinated contrast material.

• 한국안전학회지
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• 제33권5호
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• pp.15-20
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• 2018

This paper describes the fusing time characteristics of Light PVC Sheathed Circular Cord(VCTF) and Tray Frame Retardant(TFR) cables according to increased temperature under over current condition. The experimental equation will be used to determine the validity and reliability of the test results. The over current flowed 3, 5 and 10 times higher than the amount of allowable current using DC power supply with DAQ(Data Acquisition) measurement system. An infrared radiation heater, which was controlled by a variable AC auto transformer, was used to increase the temperature from room temperature to 50, 100 and 150 degrees Celsius. First, two type of cables were analyzed those with different cross-sectional areas with in the same structure and those with different structures with in the same cross-sectional areas. Then, it was determined how fusing time had been influenced according to the cross-sectional areas and different structures, respectively. The cable resistance was increased by joule heating according to increasing temperature. Therefore, the allowable current of cable is decreased. Finally, the fusing time of the cable was decreased due to increased temperatures at current flow, which were 3 times the amount of allowable current. The instantaneous breakdown was observed when current flow was 5 and 10 times over the amount of allowable current. The fusing time is directly affected by the structure of cable insulation.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume II
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• pp.752-755
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• 2006

Evaportranspiration is an important factor in hydrology cycle. Traditionally, it is measured by using basin or empirical formula with meteorology data, while it does not represent the evaportranspiration over a regional area. With the advent of improved remote sensing technology, it becomes a surface parameter of research interest in the field of remote sensing. Airborne and satellite imagery are utilized in this study. The high resolution airborne images include visible, near infrared, and thermal infrared bands and the satellite images are acquired by MODIS. Surface heat fluxes such as latent heat flux and sensible heat flux are estimate by using airborne and satellite images with surface meteorological measurements. We develop a new method to estimate the evaportranspiration over the rice paddy. The surface heat fluxes are initialized with a surface energy balance concept and iterated for convergent solution with atmospheric correct functions associated with aerodynamic resistance of heat transport. Furthermore, we redistribute the total net energy into sensible heat and latent heat fluxes. The result reveals that radiation and evaporation controlled extremes can be properly decided with both airborne and satellite images. The correlation coefficient of latent heat flux and sensible heat flux with corresponding in situ observations are 0.66 and 0.76, respectively. The relative root mean squared errors (RMSEs) for latent heat flux and sensible heat flux are 97.81 $(W/m^2)$ and 124.33 $(W/m^2)$, respectively. It is also shown that the newly developed retrieval scheme performs well when it is tested by using MODIS date.

• 한국시뮬레이션학회논문지
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• 제27권2호
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• pp.25-33
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• 2018

군용 장비 개발 시 운용자가 안정적인 환경에서 운용할 수 있도록 온도조건을 고려하여 설계하여야 한다. 각종 군용 장비를 보관하는 쉘터는 다양한 환경에서 운용되고 있다. 시험장비 및 수리부속품의 저장온도 및 운용 요구조건은 $-32^{\circ}C{\sim}50^{\circ}C$로 쉘터 내부는 저장온도 및 운용 요구조건을 충족할 수 있도록 설계되어야 한다. 본 연구에서는 MIL-STD-810G의 기준을 고려하여 고온 및 태양열 조건에서 군에서 운용중인 2.5톤의 군용쉘터의 열해석을 수행하였다. 열해석은 열저항 및 열회로개념을 활용하여 적용하였으며 해석결과를 검증하기 위해 실제 제작된 군용쉘터에 대한 태양열 시험을 실시하여 결과를 비교하여 제시하였다.

• Nuclear Engineering and Technology
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• 제52권2호
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• pp.337-343
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• 2020

Oxide dispersed strengthened (ODS) steel is an important candidate for Gen-IV reactors. Oxide embedded in Fe can help to trap irradiation defects and enhances the strength of steel. It was observed in this study that the size of oxide has a profound impact on the depinning mechanism. For smaller sizes, the oxide acts as a void; thus, letting the dislocation bypass without any shear. On the other hand, oxides larger than 2 nm generate new dislocation segments around themselves. The depinning is similar to that of Orowan mechanism and the strengthening effect is likely to be greater for larger oxides. It was found that higher shear deformation rates produce more fine-tuned stress-strain curve. Both molecular dynamics (MD) simulations and BKS (Bacon-Knocks-Scattergood) model display similar characteristics whereby establishing an inverse relation between the depinning stress and the obstacle distance. It was found that (110)_oxide || (111)_Fe (oriented oxide) also had similar characteristics as that of (100)_oxide || (111)_Fe but resulted in an increased depinning stress thereby providing greater resistance to dislocation bypass. Our simulation results concluded that critical depinning stress depends significantly on the size and orientation of the oxide.