• 센서학회지
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• 제26권2호
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• pp.135-140
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• 2017

In this paper, a novel measurement method of radial artery pulse waveform using robotic applanation tonometry (RAT) was present to reduce the errors by the pressing direction of the vessel. The RAT consisted of an array of pressure sensors and 2-axis tilt sensor, which was attached to the universal joint with a linear spring and five-DOF robotic manipulator with a one-axis force sensor. Using the RAT mechanism, the pulse sensor could be manipulated to perpendicularly pressurize the radial artery. A pilot experimental result showed that the proposed mechanism could find the optimal pressurization angles of the pulse sensor within ${\pm}3^{\circ}$standard deviations. Coefficient values of variation of maximum pulse peaks extracted from the pulse waveforms were 4.692, 6.994, and 11.039 % for three channels with the highest magnitudes. It is expected that the proposed method can be helpful to develop more precise tonometry system measuring the pulse waveform on the radial artery.

• Korean Journal of Acupuncture
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• 제40권2호
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• pp.44-53
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• 2023

Objectives : This study was conducted to reveal the relationship between multiple factors of traditional Korean Medicine diagnosis and consider the further probabilities of treating people with physical and mental problems not defined as diseases, which is called 'Mibyeong' in traditional Korean Medicine. Methods : 40 healthy participants were included in the observational clinical trial. The participants were asked to complete health questionnaires (e.g. State-Trait Anxiety Inventory, Pittsburgh Sleep Quality Index, Stress Response Inventory) and they went through a traditional diagnosis process, including four stages of diagnosis (looking, listening/smelling, inquiring, and pulse taking), by a Korean Medicine doctor. Both the Korean Medicine doctor and an artery tonometry device performed the pulse diagnosis. Results : Although all participants were healthy people with no history of disease, more than half of participants had a problem related with severe level of fatigue (n=19), sleep disturbance (n=26) and stress (n=27) status according to the related questionnaires. Participants diagnosed with phlegm syndrome by the Korean Medicine doctor showed significantly greater score in phlegm pattern questionnaires than participants who were not. However, there was little agreement between the doctor's pulse diagnosis and radial artery tonometry results. Conclusions : We conducted a pulse diagnosis and measured health-related information along with the traditional Korean Medicine diagnose procedure, including four stages of diagnosis, and we found a linkage between diagnosis of phlegm and the phlegm pattern questionnaire score. The results suggest that a number of healthy participants, with no disease diagnosed, have Mibyoung symptoms which need further clinical management. Thus, we suggest that Mibyoung management programs based on qualified diagnosis tools and traditional Korean medicine diagnosis procedures be developed, and that future research using various diagnostic tools be carried out on a large population.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2001년도 춘계학술대회 논문집
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• pp.243-248
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• 2001

A radial artery pulse wave is well known as a good mans to diagnose human body condition in th field of Chinese medical science. Information about constitution as well as organs can be obtained by detecting the artery pulse wave. Recently, the information about the human body constitution may be utilized in accelerating the recovery process of the patient on the basis of comprehensive diagnosis. A radial artery pulse wave is considered as one of promising means in examining the human body constitution. Since the examination has been conducted by the feeling of finger, the diagnosis may occasionally have uncertainty or fatal error. In this paper, a new measuring system is suggested and developed to examine the pattern of a pulse wave correctly. The system is composed of four pressure vessels, pressure sensors and air supplying pumps. One of them is utilized for appropriately pressing the radial artery, three of them for detecting pressure change in several mmHg level. The detected data is shown and discussed.

• 센서학회지
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• 제27권4호
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• pp.259-263
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• 2018

A radial artery pulse wave is measured while pressing an artery with constant force. However, pulse waveform measurements vary depending on pressing force and direction. Accurate pulse waveform measurements are important for analysis. Thus, it is necessary to define the measurement range of the permissible force and direction from which a correct pulse waveform is derived. In this study, pulse waves were generated by a pulse wave generator for accurate control. The pulse waves generated for different angles and pressing forces were analyzed. The augmentation index (AIx), which is the most commonly used index for evaluating vascular stiffness, was analyzed. The AIx was measured within ${\pm}6^{\circ}$ of the vessel direction and within ${\pm}8^{\circ}$ perpendicular to the vessel direction with a force that was 25% or more of the pressing force at which the maximum pressure wave was generated. We identified the applicable pressing force and angle range by analyzing the effect of pressing angle on the pulse wave. The AIx analysis performed using the pulse wave measurement device is reliable and reproducible.

• 센서학회지
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• 제25권2호
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• pp.138-142
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• 2016

A pulse measurement by tonometry provides useful information for diagnosis, including not only blood pressure and heart rate but also parameters for estimating a condition of the cardiovascular system. Currently, various pulse measurement devices based on the tonometry have been developed. A reliability of these devices is determined by a positioning technic between the sensor and the blood vessel and a controlling technique of the pressurization level. An angle of the sensor for the pulse measurement seems to be highly related with a measured signal, however, the objective studies for this issue have been not published. In this paper, the variation of the pulse signals by tonometry direction was experimentally assessed according to the angle of the sensor. In order for guaranteeing the repeatability of the experiment, we used a pulse generator device, which can generate human pulse signal by using silicon tube and fluid pump, and developed a structure for precise adjustment of the angle and the pressurization level of the sensor. The angle of the sensor was acquired by an inclinometer, which was attached at the opposite side of the sensor. As results, a coefficient of variation (CV) of a maximum amplitude (MA) of the pulse wave was largely increased over the angle range of $-9{\sim}9^{\circ}$. Furthermore, the changes of the pulse shape showed different aspects according to the sign of the angle tilted along the blood vessel. It is expected that the results of this study can be helpful for developing more precise pulse measurement devices based on the tonometry and applying in clinic.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2009년도 제40회 하계학술대회
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• pp.1978.1_1979.1
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• 2009

In this paper, we have proposed and demonstrated a tonometry sensor array for measuring arterial pulse pressure. A sensor module consists of 7 piezoresistive pressure sensor array. Wire-bonded connection was provided between silicon chip and lead frame. PDMS(poly-dimethylsiloxane) was coated on the sensor array to protect fragile sensor while faithfully transmitting the pressure of radial artery to the sensor. Tonometric pulse pressure can be measured by this packaged sensor array that provides the pressure value versus the output voltage.

• 전자공학회논문지SC
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• 제45권3호
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• pp.68-79
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• 2008

대동맥 증강지수는 심실의 부하뿐만 아니라 대동맥의 탄력성을 직접적으로 나타낼 수 있는 장점 때문에 동맥의 경직도를 평가하는 지표로 주목받고 있다. 하지만, 정확한 대동맥 증강지수를 계산하기 위해서는 직접 카테터를 피험자에 삽입하여 측정해야 하기 때문에 임상에 적용하기에는 한계가 존재한다. 이러한 문제점 때문에 전달함수를 이용하여 요골 동맥 맥파로부터 대동맥 맥파를 간접적으로 추정하는 방법이 이용되고 있다. 본 논문에서는 전달함수를 구하기 위하여 Millar 카테터를 이용한대동맥 맥파와 토노메트릭 방식의 압력센서를 이용하여 요골동맥 맥파를 측정하였다. 또한, 기존의 증강점 검출 알고리즘 대신단계적으로 미분 차수를 증가시키면서 증강점을 검출하는 새로운 알고리즘을 제안하였다. 10차 ARX 모델을 이용하여 전달함수를 구현하였으며, 잔차 분석을 통하여 모델을 검증하였다. 증강점 검출 알고리즘 검증을 위하여 네 가지 종류의 합성파를 만들어 제안된 알고리즘이 기존 알고리즘 보다 더 정확한 결과를 나타내는 것을 확인할 수 있었다. 본 연구는 쉽게 측정할 수 있는 요골동맥 맥파를 이용하여 대동맥의 경직도를 평가할 수 있는 방법을 제시하였으며 이를 통하여 다양한 심혈관 질환의 조기 진단에 기여할 수 있을 것이다.

• 감성과학
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• 제12권3호
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• pp.299-306
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• 2009

본 연구에서는 비침습적으로 압력 맥파를 검출하는 토노메트리 방식의 맥파 측정 장비인 SphygmoCor(AtCor, Australia)를 사용하여 측정자세에 따라 맥파를 측정하였다. 측정 결과를 통해 선 자세, 앉은 자세, 누운 자세에 따른 맥파의 분석 지표들의 변화를 분석하였다. 또한 측정된 데이터를 저혈압군, 정상혈압군, 고혈압군으로 구분하여 혈압군에 따른 맥파의 비교를 수행하였다. 그 결과 자세에 따른 요골동맥의 파형에서 유의차를 보인 분석지표는 맥파의 진폭에 해당되는 압력 보다 주요 피크가 발생되는 시간에서 나타났다. 맥압의 경우 맥파증대계수(AI)나 중심동맥압과 요골동맥압의 비율과 같이 맥압 간의 비율이 자세에 따른 변별력이 있었다. 사후검정에 따라 각 자세별로 상호 간에 모두 유의한 차이를 보인 분석지표는 주파(P_$T_1$)와 반사파(P_$T_2$)의 시간, 심박출지속시간(ED), 심박수(HR)로 나타났다. 혈압군에 대한 비교에서 대부분 맥파의 시간에 해당되는 지표보다 주요 피크의 진폭에 해당되는 맥파의 압력을 나타내는 지표가 혈압군에 따른 유의차를 보였다.