• 한국임상수의학회지
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• 제40권6호
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• pp.464-467
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• 2023

The autonomic regulation of heart rate (HR) is an indicator of the body's ability to adapt to an exercise stimulus. However, there are no reports on this topic in relation to Jeju horses used for racing. The aim of this study was to analyze the HR responses of Jeju horses during race trials and to investigate the correlation between HR and performance in these horses. HR data were collected from 17 healthy 2- to 7-year-old Jeju horses wearing HR monitors during race trials. Pearson correlation coefficients was used to determine the significance of the association between the race trial time and HR. A significant inverse correlation was observed between the race trial time (performance) and both the maximal HR (HRmax, r = -0.69, p < 0.01) and HR reserve (HRR) (HRmax - average HR during the warm-up period, r = -0.63, p < 0.01) and between the HRR and HRmax (r = 0.73, p < 0.01). Horses with a lower average HR during the warm-up period and higher heart rates during the trial achieved faster race trial times. This study reports the first HR measurements in Jeju horses during race trials, providing new insights into the HR response of this breed to exercise. The use of a noninvasive remote HR monitor system allowed assessment of exercise responses in the field, and the results suggest that both the HRR during warm-up period and HRmax may be useful performance indicators in Jeju horses.

• 산업공학
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• 제15권4호
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• pp.349-355
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• 2002

In order to build a new factory, we must have answers regarding the following questions; 1. what is to be produced? 2. how are the products to be produced? 3. how much of each product will be produced? The answers are related to product-design, process-design and capacity-design respectively and they are used for layout-design as the input data. Especially capacity design decision provides the information regarding the number of equipments required and the balance of the line. This paper introduces a case study on the capacity design for a new factory where the retainers of ball bearing are manufactured. A simulation model is developed with ARENA for analyzing the system considered. The major objectives of the study are evaluating the performance of the line which is originally suggested by the company, and finding out alternatives for improving the system. Number of WIP between the processes are also investigated because it affects the space planning of the layout.

• 한방재활의학과학회지
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• 제33권2호
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• pp.49-55
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• 2023

Objectives The purpose of this study is to analyze randomized controlled trials about neuromuscular electrical stimulation for muscle wasting with cancer patient and evaluate it's motor functionality effect. Methods Studies will be searched from 7 online databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure [CNKI], Korean studies Information Service System [KISS], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Participants will be cancer patients with muscle loss, regardless of cause, gender, race or age, interventions will be neuromuscular electrical stimulation. Other treatments than interventions will be the control group and the main outcome will be reviewed by motor functionality effect. Results Randomized controlled trials about neuromuscular electrical stimulation for muscle wasting should be included in the study. Primary outcomes include motor functionality effect. Secondary outcomes evaluate adverse event. The data uses Review Manager Software 5.4. Conclusions The conclusion of this study will provide a basis for determining whether neuromuscular electrical stimulation treatment for muscle wasting with cancer patient treatment is an effective and safe treatment method in clinical practice.

• IMMUNE NETWORK
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• 제21권1호
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• pp.5.1-5.22
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• 2021

Coronavirus disease 2019 (COVID-19) has developed as a pandemic, and it created an outrageous effect on the current healthcare and economic system throughout the globe. To date, there is no appropriate therapeutics or vaccines against the disease. The entire human race is eagerly waiting for the development of new therapeutics or vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Efforts are being taken to develop vaccines at a rapid rate for fighting against the ongoing pandemic situation. Amongst the various vaccines under consideration, some are either in the preclinical stage or in the clinical stages of development (phase-I, -II, and -III). Even, phase-III trials are being conducted for some repurposed vaccines like Bacillus Calmette-Guérin, polio vaccine, and measles-mumps-rubella. We have highlighted the ongoing clinical trial landscape of the COVID-19 as well as repurposed vaccines. An insight into the current status of the available antigenic epitopes for SARS-CoV-2 and different types of vaccine platforms of COVID-19 vaccines has been discussed. These vaccines are highlighted throughout the world by different news agencies. Moreover, ongoing clinical trials for repurposed vaccines for COVID-19 and critical factors associated with the development of COVID-19 vaccines have also been described.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 1999년도 춘계종합학술대회
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• pp.33-38
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• 1999

컴퓨터 분야에서 얼굴근육 이미지합성은 살아있는 것 같은 모델을 실현하기 위한 가장 실재적인 접근방법 중의 하나이며, 얼굴근육 모델은 얼굴조직 성분과 근육으로 구성된다. 이 모델에서 얼굴 조직 성분에 영향을 주는 힘(force)은 각 근육의 수축강도로써 계산되어지고, 각 근육 파라메터의 결합은 명확한 얼굴표현으로 결정한다. 또한 각 근육 파라메터는 실험과 샘플 사진과 근육편집기로 생성한 명확한 이미지를 비유하여 에러처리과정을 통해 결정된다. 이 논문에서 신경회로망을 사용한 2D(Two-Dimension) 지시점의 움직임으로부터 얼굴근육의 자동인식 방법을 제안하고자 하며, 얼굴모델을 기반으로 한 물리학적 제한하에 캡처된 이미지에서 정보 흐름과 2D 포인트로부터 3D(Three-Dimension) 움직임 인식을 하고자 한다.

• 복식
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• 제22권
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• pp.97-118
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• 1994

This stud is my second trial to examine the costume of Balhae Dyansty. The subject of this study is the costume of a bronze statue excavated in the Maritime Provinces of Russia. The bronze statue is in the custody of Vladivostok Museum E.V. Shavkunov a Russian archelogist reported it a statue of-ficial of balhae dynasty in the 7-8th century. Judged his report lack of basis I suggest new opinion on sex, age, married or unmarried. social position manufactured time of the statue by comparative study on the costume hair-style and appearance of the statue with around nations' antiquities. hair-style of the statue is basically included in Ssangge and complexed style of Sage Ssangsuhuange, and Guange, Generally, Ssangge is a hair style of children, unmarried women, court ladies, dancing girls, and instrument player (lady)s'. The statue wears round-necked blouse long skirt broad fabric belt at high waist broad sleeve and confront collar coat cloud shaped shawl and risen tip shoes. The figure of statue is de-scribed plump. The statue shows straight sil-houette and high waist typical style of Tang, Uddai, The most characteristic facto is cloud shaped shawl Cloud shaped shawl was originally one of the northern race's shoulder ornaments. From the view of Comparative study the antiquities of NamDang and JunChock are simi-lar to this statue. Besides Tsukanovka river where the statue was excavated is Kraskino ruins of a castle formed single cultural layer of Balhae Dynasty and are relics of the layer of Balhae Dynasty and are relics of the latter period of Balhae Dynasty. Therefore this statue is assumed to have been manufactured at the last years of Balhae Dynasty and to be a figure of unmarried woman not official.

• 기술혁신학회지
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• 제12권1호
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• pp.237-264
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• 2009

선도적으로 기술창출단계의 기술혁신에 성공하여 최초경로로 기술리더가 된 국내기업에 대한 혁신 연구는 새롭게 도전하려는 국내기업과 개발도상국기업에게 시행착오를 줄일 수 있는 시사점을 제공할 수 있다. 그러나 개발도상국기업의 기술창출단계 혁신에 대한 연구가 부족하며, 특히 프로세스혁신에 대한 연구는 제품혁신연구에 비해 더욱 부족한 상황이다. 본 연구는 기술창출단계의 프로세스 기술혁신 프로젝트를 대상으로 하는 탐색적 연구이다. 최초경로로 기술리더가 된 POSCO의 FINEX(파이넥스) 사례에서는 기술창출단계 혁신은 기술내재화단계 고도화의 연장선이라기보다는 높은 위험을 감수하는 최고경영층의 결단에 의해 시도되는 불연속적인 특성이 있으며, 기술창출단계 혁신을 시작하는 개발도상국기업이 일반적으로 초기에 직면하는 원천기술을 개발을 위한 기술역량의 부족은 원천기술을 개발 중인 선발자와의 보완적 기술협력을 통해 극복하였다. 그리고 선진국 경쟁자보다 뒤늦게 기술 개발을 시작하였지만 가장 먼저 상용화단계에 도달할 수 있었던 것은 기술개발 가속화(Speed-up)로 기술개발속도에 영향을 주는 세부요인을 파악하였다.

• 응용통계연구
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• 제37권2호
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• pp.225-237
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• 2024

경쟁위험자료에서 일부 공변량들이 연구대상들의 일부분에 대해 관측되지 않을 수 있다. 그런 경우 결측된 공변량 값을 가진 연구대상들을 분석에서 제외하는 것은 편향된 추정치와 효율성 손실이 발생할 수 있다. 본 논문에서는 누락된 공변량을 가진 원인별 비례위험모형의 회귀모수 추정을 위해 다중대체 방법과 증대된 역 확률 가중 방법을 연구하였다. 모의실험을 통해 다중대체 방법과 증대된 역 확률 가중 방법에 의해 구해진 추정량의 성능을 평가한 결과, 이 방법들이 잘 수행됨을 확인하였다. 미국 국립암연구소의 전립선, 폐, 대장, 난소 암 선별 시험 연구에서 제공하는 종양 크기의 값이 누락된 유방암 자료에 대해 암 사망 위험률과 다른 원인 사망 위험률에 유의한 영향을 미치는 요인을 파악하기 위해 다중대체 방법과 증대된 역 확률 가중 방법을 적용하였다. 다중대체 방법과 증대된 역 확률 가중 방법에 의해 원인별 비례위험모형을 적합한 결과, 인종, 기혼여부, 병기, 분화도, 종양의 크기는 유방암 사망 위험률에 유의한 영향을 미치는 요인들이였으며, 병기가 유방암 사망 위험률을 높이는데 가장 큰 영향을 미치는 요인임을 확인하였다. 진단시 연령과 종양의 크기는 다른 원인 사망 위험률을 높이는데 유의한 영향을 미치는 요인이였다.