• Title/Summary/Keyword: r-interior

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Presence of Tumour-infiltrating FOXP3+ Lymphocytes Correlates with Immature Tumour Angiogenesis in Renal Cell Carcinomas

  • Zhan, Hai-Lun;Gao, Xin;Zhou, Xiang-Fu;Pu, Xiao-Yong;Wang, De-Juan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.3
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    • pp.867-872
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    • 2012
  • Background: $FOXP3^+$ regulatory T cells (Tregs) inhibit effector T cell functions and are implicated in tumour progression. However, together with microvessel density (MVD) they remain controversial prognostic predictors for renal cell carcinoma (RCC), and potential associations have yet to be determined. The objective of this study was to determine the prognostic significance of Tregs and MVD and their potential relationship in RCCs. Design: Paraffin-embedded tissues from 62 RCC patients were analysed using immunohistochemistry to detect $FOXP3^+$ lymphocytes, and double immunohistochemistry to detect different microvessel types in the tumour interior, rim and normal kidney tissue, and their correlation with clinicopathological characteristics. Survival analysis was also performed. Results: The presence of $FOXP3^+$ cells in the tumour interior or the rim showed no correlation with death from RCC and other pathological characteristics. Negative correlations were noted between the immature MVD in the tumour interior or the rim and tumour size, tumour stage and overall survival; however, there was no correlation with the nuclear grade or pathological type. A positive correlation between $FOXP3^+$ Tregs and immature MVD (r=0.363, P=0.014) and mature MVD (r=0.383, P=0.009) was confirmed in the tumour interior. However, there was no correlation between $FOXP3^+$ Tregs and mature MVD (r=0.281, P=0.076) or immature MVD (r=0.064, P=0.692) in the tumour rim. Conclusions: In this study, a positive correlation between the presence of $FOXP3^+$ Tregs and immature and mature MVD in RCC was confirmed, which suggests a link between suppression of immunity, tumour angiogenesis and poor prognosis.

APPROXIMATION OF CONVEX POLYGONS

  • Lee, Young-Soo
    • Journal of applied mathematics & informatics
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    • v.10 no.1_2
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    • pp.245-250
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    • 2002
  • Consider the Convex Polygon Pm={Al , A2, ‥‥, Am} With Vertex points A$\_$i/ = (a$\_$i/, b$\_$i/),i : 1,‥‥, m, interior P$\^$0/$\_$m/, and length of perimeter denoted by L(P$\_$m/). Let R$\_$n/ = {B$_1$,B$_2$,‥‥,B$\_$n/), where B$\_$i/=(x$\_$i/,y$\_$I/), i =1,‥‥, n, denote a regular polygon with n sides of equal length and equal interior angle. Kaiser[4] used the regular polygon R$\_$n/ to approximate P$\_$m/, and the problem examined in his work is to position R$\_$n/ with respect to P$\_$m/ to minimize the area of the symmetric difference between the two figures. In this paper we give the quality of a approximating regular polygon R$\_$n/ to approximate P$\_$m/.

A Cogging Torque Reduction Method for Interior Permanent Magnet Synchronous Motor Considering Radial Flux Density (Radial Flux Density를 고려한 매입형 영구자석 동기전동기 코깅토크 저감 방법)

  • Park, Kyung-Soo;Lee, Jin hwan;Han, Wonseok;Kim, Yong-Jae;Jung, Sang-Yong
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.790-791
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    • 2015
  • 본 논문에서는 Radial flux density($B_r$)를 고려하여 매입형 영구자석 동기 전동기(Interior Permanent Magnet Synchronous Motor, IPMSM)에서 진동, 소음 발생의 원인이 되는 코깅토크를 최적화하는 방법을 제시한다. Maxwell Stress Method에 의하면 토크는 $B_r$에 비례한다. 따라서 $B_r$과 토크의 상관관계를 이용하여 코깅토크를 저감시켰다. 코깅토크가 가장 큰 회전자의 위치에서 회전자 표면의 $B_r$을 확인한 후 에 노치(Notch)를 적용할 위치를 선정하였다. 그리고 제안한 방법이 매입형 영구자석 동기 전동기 모델에서 효과적으로 코깅토크를 저감시키는 것을 유한요소법을 통해 검증하였다.

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Development of Interior type Permanent Magnet Synchronous Motor for Electric Golf Car (전동 골프카 구동용 매입형 영구자석 동기전동기 개발)

  • Oh, Young-Jin;Ryu, Sung-Lay;Kim, Ji-Hyun;Lee, In-Woo
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1025-1026
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    • 2007
  • Recently study on components for a electric golf car and a utility car driven by a electric motor has been performed actively, and the study on a drive motor, a inverter and a battery focuses on a small, light weight and high power density source to improve fuel efficiency using limited electric energy. Especially, since a utility car such as a golf car performance depends on initial acceleration and maximum speed capability, a drive system requires high power and large and wide operation area, This study therefore investigates on the interior permanent magnet synchronous motor with high power density and wide operation, and is verified with the test result after design and characteristic analysis is performed

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Structural Analysis for VVIP Cabin Compartment Modification STC of Commercial Airplane

  • Lee, Sang Hoon;Bang, Dae Han;Choi, Sang Min;Choi, Hang Suk
    • Journal of Aerospace System Engineering
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    • v.15 no.4
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    • pp.30-39
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    • 2021
  • This paper presents a study on the design and structural substantiation of the interior structure of the new VVIP aircraft. In this study, the structural design and analysis of the compartment with aluminum alloy and sandwich composite panel were performed. The structural design requirements from the Federal Aviation Administration were identified. The structural analysis of the compartment was performed by the utilization of the finite element analysis method, for the structural design process. Therefore, the designed cabin compartment secured the structural integrity, and satisfied its certification standards and design requirements via structural analysis.

Color Preference of the Elderly for the Apartment Interior Color planning (노인수요계층의 아파트 실내 색채계획을 위한 색채선호 연구)

  • Jun, Eun-Jung;Cho, Sung-Heui
    • Korean Institute of Interior Design Journal
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    • v.15 no.6 s.59
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    • pp.221-228
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    • 2006
  • The purpose of this research is to investigate the tendency of color preference for the elderly in housing. For this, a questionnaire survey was carried out with color chips and 9 photos of the living rooms which were chosen among apartment model houses in Pusan. Preference of color usage was measured by SD scale developed by advertising adjectives for the model houses. The result of this study are as follows: 1) The preferred color image was characterized as soft, warm and simple. The main factors of color image were identified and named as 'dignity factor' and 'personality factor'. 2) The elderly preferred G generally, but R for dominant color of the living room. They distinguished their attitudes about the color by the purpose of color usage. 3) For colors of architectural components of the living room, preferred colors were narrowed Y, YR and R for wall, art wall and floor. Beige was the most popular color in the living room for the elderly. This research can contribute to the basic data of color planning for the elderly housing.

A Study on Electronically Controlled R-134a Heat Pump System for a Fuel Cell Electric Vehicle (FCEV) (연료전지 자동차용 R-134a 전동식 히트펌프 시스템 개발에 관한 연구)

  • Lee, Jun-Kyoung;Lee, Dong-Hyuk;Won, Jong-Phil
    • Transactions of the Korean Society of Automotive Engineers
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    • v.15 no.3
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    • pp.124-132
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    • 2007
  • The main objective of this work is to investigate the characteristics of a heat pump system for fuel cell electric vehicle (FCEV). The present heat pump system adopts an electrically driven compressor running with R134a and uses the heat from the fuel cell stack as the heat source for the exterior heat exchanger. The experimental work has been done with various operating conditions such as different compressor speeds, fuel cell stack coolant temperatures and flow rates. The heating capacity was measured to be from 4 to 10 kW at $-20^{\circ}C$ ambient temperature, and the outlet temperature of interior heat exchanger was up to $70^{\circ}C$. After 30 seconds from start-up, the system reached a steady state and the heating capacity of 6.8 kW was acquired, and after 90 seconds, the air outlet temperature of interior heat exchanger became $35^{\circ}C$.

Spatial Transfigurations by Floor Plan Type of Elderly Center in Apartment Complex (아파트 단지 내 경로당의 평면유형에 따른 공간변용)

  • Yang, Se-Hwa;Ryu, Hyun-Joo
    • Journal of Families and Better Life
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    • v.31 no.1
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    • pp.29-37
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    • 2013
  • The purposes of the study were to try configuring categorization of floor plans of elderly centers located in apartment complexes and to find out the spatial transfigurations regarding floor plan types. The data for the analysis of the study were collected from 56 elderly centers of apartment complexes in Ulsan by observations and interviews from July 3 through 13, 2012. The results are as follows. Firstly, the floor plans of the elderly centers were categorized into six types, which were 2R+L+K, 2R+LK, 1R+L+K/1R+LK, 1RL+K, 1RLK, and 2R+K/1R+K(no living room). Secondly, there were no salient differences among the plan types for the characteristics of physical environment of the centers. The types of 2R+L+K were relatively big in size and two thirds of the centers had gender-segregated rooms. Lastly, spatial transfigurations was found in sixty-percent of the centers, which included change of spatial arrangement, functional change, and functional addition. Interestingly, the more the spaces were segregated, the more the spatial transfigurations were performed in the way for the integration of functions of the rooms.

A Study on the Constructive Layers of Body Perception in Contemporary Architecture Space - Focused on the HdM, Sejima, R. Koolhaas's Works - (현대건축공간에 나타나는 신체지각의 구축 층위 연구 - HdM, Sejima, R. Koolhaas의 건축 작품을 중심으로 -)

  • Oh, Sang-Eu
    • Korean Institute of Interior Design Journal
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    • v.26 no.4
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    • pp.12-21
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    • 2017
  • This study is on the constructive ways of body perception applied to architecture space. This research also has a purpose of extending the range of possibility of body perception's application. Research on the phenomenological method applied to architecture space was mainly focused on sensation, which made limited awareness on the range of body perception. The scope of body perception includes not only sensation, but also perception, cognition, and human behavior. Therefore this study explicate how operant features of body perception works together. Operant features of body perception are perception as cognition, synesthesia, and Interaction with others. Herzog & de Meuron, Sejima, and R. Koolhaas's works are reviewed to verify these features of body perception.

Spin-up in a Cylinder with a Time-Dependent Rotation Rate (시간에 따라 변화는 회전 각속도를 가지는 원통용기내의 스핀업)

  • Kim, Kyung-Seok;Kwak, Ho-Sang;Hyun, Jae-Min
    • Proceedings of the KSME Conference
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    • 2001.06e
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    • pp.456-462
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    • 2001
  • Comprehensive numerical computations are made of a homogenous spin-up in a cylindrical cavity with a time-dependent rotation rate. Numerical solutions are acquired to the governing axisymmetric cylindrical Navier-Stokes equation. A rotation rate formula is ${\Omega}_f={\Omega}_i+{\Delta}{\Omega}(1-{\exp}(-t/t_c))$. If $t_c$ is large, it implies that a rotation change rate is small. The Ekman number, E, is set to $10^{-4}$ and the aspect ratio, R/H, fixed to I. For a linear spin-up(${\epsilon}<<$), the major contributor to spin-up in the interior is not viscous-diffusion term but inviscid term, especially Coriolis term, though $t_c$ is very large. The viscous-diffusion term only works near sidewall. But for spin-up from rest, when $t_c$ is very large, viscous-diffusion term affects interior area as well as sidewall, initially. So azimuthal velocity of interior for large $t_c$ appears faster than that of interior for relatively small $t_c$. However, the viscous-diffusion term of interior decreases as time increases. Instead, inviscid term appears in the interior.

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