• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.20 no.2
• /
• pp.659-669
• /
• 1996

To clarify the effects of equivalence ratio, initial pressure and temperature on the flame propagation and radicals characteristics, a series of the experimental study were conducted in a quiescent methane-air premixture using a constant volume chamber. The development of the flame was visualized following the start of ignition using high speed schlieren photo and radical images by intensified CCD camera. Combustion pressure and ion current were recorded simultaneously according to the experimental conditions which were equivalence ratio with 0.7 to 1.2, initial pressure with 0.08 MPa to 0.40 MPa and initial premixture temperature with 3l3.2K to 403.2K. The results showed that the flame speed by ion current and mass fraction burned by combustion pressure characterized the effects of flame propagation very well. And increased combustion duration due to lean combustion condition that was below equivalence ratio, 0.8 caused cycle variation and decreasing the power of engine.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.43 no.10 s.352
• /
• pp.118-125
• /
• 2006

A new error amplifier is presented for fast transient response of DC-DC converters. The amplifier has low quiescent current to achieve high power conversion efficiency, but it can supply sufficient current during large signal operation. Two comparators detect large-signal variations, and turn on extra current supplier if necessary. The amount of extra current is well controlled, so that the system stability can be guaranteed in various operating conditions. The simulation results show that the new error amplifier achieves significant improvement in transient response than the conventional one.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.13 no.9
• /
• pp.882-888
• /
• 2002

This paper proposed a bias stability circuit that compensates the degradation of MMIC's performance for the variation of the process and temperature. The proposed bias circuit proved the superior effect compared with the conventional bias circuit using the constant current source. It designed and fabricated simultaneously two amplifier on one layout for comparison in same conditions. One is amplifier with conventional bias circuit using constant current source and the other is amplifier with proposed bias stability circuit. The chip was measured the microwave performances under process variation that classed the level NOM, MIN and MAX. The amplifier with a conventional bias circuit using constant current source has 6.4 dB gain variation and 7 mA Ids variation at 1.8 GHz, but the amplifier with the proposed bias circuit has the 2.1 dB gain variation and 3 mA Ids variation. As the result, MMIC having the proposed bias circuit shows the superior compensation of the quiescent point than the MMIC having the conventional bias circuit under the variations of the process and temperature and can improve the yield of the MMIC. The fabricated chip size is 1.2 mm $\times$ 1.4 mm.

• Journal of IKEEE
• /
• v.8 no.1 s.14
• /
• pp.12-21
• /
• 2004

Error control is one of major concerns in many electronic systems. Experience shows that most malfunctions during system operation are caused by transient faults, which often mean abnormal signal delays that may result in violations of circuit element timing constraints. This paper presents a novel CMOS-based concurrent timing error detector that makes a flip-flop to sense and then signal whether its data has been potentially corrupted or not by a setup or hold timing violation. Designed circuit performs a quiescent supply current evaluation to determine timing violation from the input changes in relation to a clock edge. If the input is too close to the clock time, the resulting switching transient current in the detection circuit exceeds a reference threshold at the instant of the clock transition and an error is flagged. The circuit is designed with a $0.25{\mu}m$ standard CMOS technology at a 2.5 V supply voltage. The validity and effectiveness are verified through the HSPICE simulation. The simulation results in this paper shows that designed circuit can be used to detect setup and hold time violations effectively in clocked circuit element.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2007.08a
• /
• pp.1005-1008
• /
• 2007

In this study, an architecture for 262K-color TFT-LCD source driver. In this paper proposed the chip consumes smaller area and static current which is suitable for QVGA resolutions. In the conventional structures, all of them need large number of OPAMP buffers to drive the pixels, Therefore, highly resistive R-DACs are needed to generate gamma voltages to reduce the static current. In this study, our design only used two OPAMPs and low resistance RDACs without increasing the quiescent current. Thus, it was experted that chip would be more in consuming lower static power for longer battery lifetime. The source driver were implemented by the 3.3 V $0.35\;{\mu}m$ CMOS technology provided by TSMC. The area of the core OPAMP circuit was about $110\;{\mu}m\;{\times}\;150\;{\mu}m$ and that of the source driver was $880\;{\mu}m\;{\times}\;430\;{\mu}m$. As compared to the conventional structure, approximately 64.48 % in area was achieved.

• KSTLE International Journal
• /
• v.6 no.1
• /
• pp.28-32
• /
• 2005

The electrorheoloRical (ER) fluids are composed of a colloidal dispersion of polarizable particles in insulating oil, and it's the rheological property changes by the applied electric field. These changed are reversible and occur fast within a fewmilliseconds. The ER properties of the ER fluid such as increment of viscosity and yield stress come from the particle chain structure induced by electric fleld. When formulating the ER fluid for a speciflc application, some requirement must besatisfled, which are high yield stress under electric field, rapid response, and dispersion stability. While this characteristic makes valuable ER fluids in valious industrial applications, their lung term and quiescent application has been limited because ofproblems with particle sedimentation. In an effort to overcome sedimentation problem of ER fluids, the anhydrous ER materials of monodispersed hollow polyaniline (PANI) and adipate derivative respectively with submicron-sized suspension providing wide operating temperature range and other advantage were synthesized in a four-step procedure. The ER fluidswere characterized by FT-lR, TGA, DLS, SEM, and TEM. Stability of the suspensions was examined by an UV spectroscopy.The rheological and electrical properties of the suspension were investigated Couette-type rheometer with a high voltagegenerator, current density, and conductivity. And the behavior of ER suspensions was observed by a video camera attached toan optical microscope under 3kV/mm. The suspensions showed good ER properties, durability, and particle dispersion.

• The Bulletin of The Korean Astronomical Society
• /
• v.43 no.1
• /
• pp.31.1-31.1
• /
• 2018

While astronomers are working hard to detect the earliest galaxies and to follow their evolution to redshift z~0, they remain baffled by the present-day dichotomy between disky, star forming (aka late-type) galaxies and quiescent, spheroidal (aka early-type) galaxies. The key is to find galaxies in transition from one class to the other, whose spectra indicate intense recent star formation that has now ended. We have identified thousands of such "post-starburst galaxies" and discovered that they are often the products of late-type galaxy-galaxy mergers. Their current kinematics, stellar populations, and morphologies are consistent with late- to early-type galaxy evolution. I will discuss recent work that suggests new connections between this violent history and the central supermassive black hole. In particular, the molecular gas reservoir of a post-starburst galaxy declines rapidly after the starburst ends and in a manner consistent with feedback from an active nucleus. Furthermore, a star is ~300x more likely to be tidally disrupted by the nucleus of a post-starburst galaxy than in other galaxies. Like the well-known black hole-bulge mass correlation, these surprising links between the properties of a galaxy on kpc scales and its supermassive black hole on pc scales require explanation.

• Clinical Endoscopy
• /
• v.56 no.5
• /
• pp.563-577
• /
• 2023

In inflammatory bowel disease (IBD), chronic inflammation leads to unfavorable clinical outcomes and increases the risk of developing colorectal neoplasm (CRN); thereby highlighting the importance of endoscopically evaluating disease activity as well as detecting and characterizing CRN in patients with IBD. With recent advances in image-enhanced endoscopic (IEE) technologies, especially virtual chromoendoscopy (VCE) platforms, this review discusses state-of-the-art IEE techniques and their applicability in assessing disease activity and surveillance colonoscopy in patients with IBD. Among various IEE, VCE demonstrated the capacity to identify quiescent disease activity. And endoscopic remission defined by the new scoring system using VCE platform better predicted clinical outcomes, which may benefit the tailoring of therapeutic strategies in patients with IBD. High-definition dye-chromoendoscopy (HD-DCE) is numerically superior to high-definition white light endoscopy (HD-WLE) in detecting CRN in IBD; however, discrepancy is observed in the statistical significance. VCE showed comparable performance in detecting dysplasia to HD-WLE or DCE and potential for optical diagnosis to differentiate neoplastic from nonneoplastic lesions during surveillance colonoscopy. Applying these novel advanced IEE technologies would provide opportunities for personalized medicine in IBD and optimal treatment of CRN in patients with IBD.

• The Bulletin of The Korean Astronomical Society
• /
• v.43 no.1
• /
• pp.34.2-35
• /
• 2018

Galaxy transition from star-forming to quiescent, accompanied with morphology transformation, is one of the key unresolved issues in extragalactic astronomy. Although several environmental mechanisms have been proposed, a deeper understanding of the impact of environment on galaxy transition still requires much exploration. My Ph.D. thesis focuses on which environmental mechanisms are primarily responsible for galaxy transition in different environments and looks at what happens during the transition phase using multi-wavelength photometric/spectroscopic data, from UV to mid-infrared (MIR), derived from several large surveys (GALEX, SDSS, and WISE) and our GMOS-North IFU observations. Our multi-wavelength approach provides new insights into the *late* stages of galaxy transition with a definition of the MIR green valley different from the optical green valley. I will present highlights from three areas in my thesis. First, through an in-depth study of environmental dependence of various properties of galaxies in a nearby supercluster A2199 (Lee et al. 2015), we found that the star formation of galaxies is quenched before the galaxies enter the MIR green valley, which is driven mainly by strangulation. Then, the morphological transformation from late- to early-type galaxies occurs in the MIR green valley. The main environmental mechanisms for the morphological transformation are galaxy-galaxy mergers and interactions that are likely to happen in high-density regions such as galaxy groups/clusters. After the transformation, early-type MIR green valley galaxies keep the memory of their last star formation for several Gyr until they move on to the next stage for completely quiescent galaxies. Second, compact groups (CGs) of galaxies are the most favorable environments for galaxy interactions. We studied MIR properties of galaxies in CGs and their environmental dependence (Lee et al. 2017), using a sample of 670 CGs identified using a friends-of-friends algorithms. We found that MIR [3.4]-[12] colors of CG galaxies are, on average, bluer than those of cluster galaxies. As CGs are located in denser regions, they tend to have larger early-type galaxy fractions and bluer MIR color galaxies. These trends can also be seen for neighboring galaxies around CGs. However, CG members always have larger early-type fractions and bluer MIR colors than their neighboring galaxies. These results suggest that galaxy evolution is faster in CGs than in other environments and that CGs are likely to be the best place for pre-processing. Third, post-starburst galaxies (PSBs) are an ideal laboratory to investigate the details of the transition phase. Their spectra reveal a phase of vigorous star formation activity, which is abruptly ended within the last 1 Gyr. Numerical simulations predict that the starburst, and thus the current A-type stellar population, should be localized within the galaxy's center (< kpc). Yet our GMOS IFU observations show otherwise; all five PSBs in our sample have Hdelta absorption line profiles that extend well beyond the central kpc. Most interestingly, we found a negative correlation between the Hdelta gradient slopes and the fractions of the stellar mass produced during the starburst, suggesting that stronger starbursts are more centrally-concentrated. I will discuss the results in relation with the origin of PSBs.

• Journal of Life Science
• /
• v.34 no.6
• /
• pp.418-425
• /
• 2024

Solid tumors are heterogeneous populations of multiple cell types. While the majority of the cells that comprise cancer are unable to divide, cancer stem cells have self-renewal and differentiation properties. Normal stem cell pathways that control self-renewal are overactivated in cancer stem cells, making cancer stem cells important for cancer cell expansion and progression. Dick first proposed the definition of cancer stem cells in acute myeloid leukemia, according to which cancer stem cells can be classified based on the expression of cell surface markers. Cancer stem cells maintain their potential in the tumor microenvironment. Multiple cell types in the tumor microenvironment maintain quiescent cancer stem cells and serve as regulators of cancer growth. Since current cancer treatments target proliferative cells, quiescent state cancer stem cells that are resistant to treatment increase the risk of recurrence or metastasis. Various signals of the tumor microenvironment induce changes to become a tumor-supportive environment by remodeling the vasculature and extracellular matrix. To effectively treat cancer, cancer stem cells and the tumor microenvironment must be targeted. Therefore, it is important to understand how the tumor microenvironment induces reprogramming of the immune response to promote cancer growth, immune resistance, and metastasis. In this review, we discuss the cellular and molecular mechanisms that can enhance immunosuppression in the tumor microenvironment.