• Korean Journal of Radiology
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• v.23 no.1
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• pp.112-123
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• 2022

Objective: To investigate the relationship between ¹⁸F-FDG PET/CT semi-quantitative parameters and the International Association for the Study of Lung Cancer, American Thoracic Society/European Respiratory Society (IASLC/ATS/ERS) histopathologic classification, including histological subtypes, proliferation activity, and somatic mutations. Materials and Methods: This retrospective study included 419 patients (150 males, 269 females; median age, 59.0 years; age range, 23.0-84.0 years) who had undergone surgical removal of stage IA-IIIA lung adenocarcinoma and had preoperative PET/CT data of lung tumors. The maximum standardized uptake values (SUVmax), background-subtracted volume (BSV), and background-subtracted lesion activity (BSL) derived from PET/CT were measured. The IASLC/ATS/ERS subtypes, Ki67 score, and epidermal growth factor/anaplastic lymphoma kinase (EGFR/ALK) mutation status were evaluated. The PET/CT semi-quantitative parameters were compared between the tumor subtypes using the Mann-Whitney U test or the Kruskal-Wallis test. The optimum cutoff values of the PET/CT semi-quantitative parameters for distinguishing the IASLC/ATS/ERS subtypes were calculated using receiver operating characteristic curve analysis. The correlation between the PET/CT semi-quantitative parameters and pathological parameters was analyzed using Spearman's correlation. Statistical significance was set at p < 0.05. Results: SUVmax, BSV, and BSL values were significantly higher in invasive adenocarcinoma (IA) than in minimally IA (MIA), and the values were higher in MIA than in adenocarcinoma in situ (AIS) (all p < 0.05). Remarkably, an SUVmax of 0.90 and a BSL of 3.62 were shown to be the optimal cutoff values for differentiating MIA from AIS, manifesting as pure ground-glass nodules with 100% sensitivity and specificity. Metabolic-volumetric parameters (BSV and BSL) were better potential independent factors than metabolic parameters (SUVmax) in differentiating growth patterns. SUVmax and BSL, rather than BSV, were strongly or moderately correlated with Ki67 in most subtypes, except for the micropapillary and solid predominant groups. PET/CT parameters were not correlated with EGFR/ALK mutation status. Conclusion: As noninvasive surrogates, preoperative PET/CT semi-quantitative parameters could imply IASLC/ATS/ERS subtypes and Ki67 index and thus may contribute to improved management of precise surgery and postoperative adjuvant therapy.

• Proceedings of the Korean Magnestics Society Conference
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• 2001.04a
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• pp.112-113
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• 2001

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.3
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• pp.506-515
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• 2004

The objective of this study was to compare the rate of in vitro demineralization of bovine permanent (BP), human deciduous (HD) and human permanent (HP) enamel. Twenty aye flattened and polished enamel samples for each group (BP, HD, HP) were immersed in a demineralizing solution (0.1 mol/L lactic acid, 0.2% Carbopol 907, and 50% saturated hydroxyapatite) for 1, 2, 4 or 8 days. All 25 samples from each group were subjected to Quantitative light induced fluorescence analysis (QLF) and 5 samples from each group were randomly selected for Transverse Microradiography analysis (TMR). Integrated mineral loss (IML) and lesion depth (LD) were determined by TMR. The fluorescence radiance (FR) of sound enamel $(FR_S)$, demineralized enamel $(FR_D)$ were determined by QLF and FR ratio $(FR_D/FR_S)$ was calculated. Bovine enamel samples showed significant correlation between FR ratio and lesion depth(p<0.05) and deciduous enamel samples does not showed significant correlation between FR ratio and lesion depth(p>0.05). Permanent enamel samples showed significant correlation between FR ratio and lesion depth(p<0.05) The constant of demineralization time between FR ratio from regression analysis were as follows: bovine enamel was -4.643(p<0.05) deciduous enamel was -5.421(p<0.05) and permanent enamel was -4.435(p<0.05).

• Journal of the Institute of Convergence Signal Processing
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• v.23 no.3
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• pp.143-149
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• 2022

This excerpt delineates a quantitative measure of relationship between a research title and its respective abstract extracted from different journal articles documented through a Korean Citation Index (KCI) database published through various journals. In this paper, we propose a machine learning-based similarity metric that does not assume normality on dataset, realizes the imbalanced dataset problem, and zero-variance problem that affects most of the rule-based algorithms. The advantage of using this algorithm is that, it eliminates the limitations experienced by Pearson correlation coefficient (r) and additionally, it solves imbalanced dataset problem. A total of 107 journal articles collected from the database were used to develop a corpus with authors, year of publication, title, and an abstract per each. Based on the experimental results, the proposed algorithm achieved high correlation coefficient values compared to others which are cosine similarity, euclidean, and pearson correlation coefficients by scoring a maximum correlation of 1, whereas others had obtained non-a-number value to some experiments. With these results, we found that an effective title must have high correlation coefficient with the respective abstract.

• Analytical Science and Technology
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• v.33 no.3
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• pp.143-150
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• 2020

In this study, crude protein was analyzed and compared using the Kjeldahl and Dumas method for cereals, meat, sea food, chemical samples and vegetable. The nine kinds of cereal, including white rice, were analyzed. In the result, the correlation coefficient of the Kjeldahl and the Dumas method indicated that there was no significant difference between them, showing 0.994 of it and 0.956 of p-value. Also, for the nine kinds of meat, five kinds of sea food, three kinds of chemical samples, four kinds of vegetable, there was little difference about the correlation coefficient of the Kjeldahl and the Dumas method, showing 0.9725, 0.9879, 0.9985 and 0.9873 of it and 0.947, 0.761, 0.997 and 0.727 of p-value, respectively. For the samples of meat, they were not fully homogenized, so the reproducibility of them was not good in the Dumas method, which is required to be analyzed in small size. However, when vegetables, which contain a lot of nitrates, are analyzed using Kjeldahl, they showed the lower reproducibility compared to the result of using Dumas because they are not completely decomposed in the Kjeldahl method. In the Dumas method, the samples should be homogenized because only 0.1 g sample is used. In short, neither of the Kjeldahl and Dumas methods are an accurate quantitative test because both of them do not directly analyze pure protein but measure the amount of protein based on analysis of nitrogen. Therefore, it is important of selecting the appropriate analysis method considering the characteristics of samples.

• Journal of Chest Surgery
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• v.27 no.10
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• pp.833-837
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• 1994

Lung contusion due to blunt chest trauma is the most common lung injury and correlated with the clinical course and prognosis. Its diagnosis by CT[Computerized Tomogram] gives a more clear and understandable three dimensional view, by which we are able to measure the volume of the contused and entire lung. Other variables are arterial blood gas, number of rib fracture, presence of hemopneumothorax, sternal fracture and clavicle fracture, number of associated non-thoracic injuries, ventilator time and presence of pulmonary complication. Percentage[%] of lung contusion are expressed as mean $\pm$ standard deviation and data analysis was performed by means of multivariate repeated measures analysis of variance to detect significant differences in variables between positive thoracic injury group and negative group. The paired t-test was used. Differences of percentage of lung contusion between groups were assessed by one-way analysis of variance. Simple linear regression was used to perform correlation analysis in the number of rib fracture and ventilator time. A p value less than 0.05 was considered statistically significant. Pneumothorax and the number of associated other injuries affect the amount of lung contusion and pulmonary complication group has more contused lung volume. Arterial blood gas study shows no correlation with the amount of lung contusion statistically. The number of rib fracture correlated with the amount of lung contusion, which also correlated with ventilator time[r=0.56, p<0.05]. In conclusion, quantitative anlysis of lung contusion by CT predicts the clinical course and treatment such as ventilator care.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.5
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• pp.798-804
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• 2012

Although siderophores are induced primarily in response to iron deficiency, soil and other ecological factors can affect on this process. This study was to evaluate the production of siderophores by different fungal species isolated from heavy metal contaminated and uncontaminated soils. More than thirty fungal strains were isolated from heavy metal contaminated and rhizosphere uncontaminated soils. Chrome azurol sulfonate (CAS) was used for both quantitative and qualitative evaluation of siderophores production. No significant correlations were observed between the tested variables such as ultraviolet (UV) irradiation method and CAS-agar plate and heavy metal concentration in both soils. The production of siderophores in rhizosphere fungi was higher than those isolated from the contaminated soil; however, the difference was not significant. The siderophore production (%) by fungi isolated from heavy metal contaminated soil using UV irradiation method was positively correlated with the qualitative values using CAS-plate method (P<0.05). Pearson correlation test indicated a positive correlation between the quantitative and qualitative methods of detection for fungi isolated from rhizosphere and also those isolated from heavy metal contaminated soil.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.24 no.1
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• pp.137-147
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• 1994

A digital imaging system using Machintosh Ⅱ ci computer, high resolution Sony XC-77 CCD camera, Quickcapture Frame Grabber Board was evaluated for quantitative analysis of standardized periapical film with aluminum step wedge. The results were as follows: 1. Correlation between Al thickness and gray level was high-positively associated(r²=0.99, p<0.001). 2. Correlation between measured weight of experimental lesion and estimated relative lesion volume by digital subtracted radiography was also high-positively associated (r²=0.98, p<0.001). 3. As exposure time was increased, mean gray level was decreased(p<0.01) and slope of regression line between Al thickness and gray level was also decreased (p<0.01). And when the exposure time was shorter than 0.2 second, the value of r² was relatively low. On the basis of the above results, it is considered that this digital imaging system using a Macintosh Ⅱ ci computer & a high resolution CCD monochrome camera will be useful in evaluating digitized image from standardized periapical film quantitatively.

• Korean Journal of Applied Biomechanics
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• v.26 no.1
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• pp.1-9
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• 2016

Objective: The aim of this study is to investigate the association between dance experience and smoothness of hand trajectory during dance by using three jerk-based quantitative methods (integrated squared jerk, mean squared jerk, and dimensionless jerk). Methods: Eleven Korean traditional dancers whose experience of dancing ranged from 5 years to 20 years participated in this study. Dancers performed the Taeguksun motion in Korea traditional dance. Six infrared cameras were used to capture the movement of the hands of the dancers. The smoothness of hand movement was calculated using three jerk-based methods. Results: With regard to the smoothness of the right hand, dance experience was significantly correlated with dimensionless jerk (r=0.656, p=0.028), while dance experience was not significantly correlated with integrated squared jerk (r=0.581, p=0.552) and mean squared jerk. With regard to the smoothness of the left hand, there was no correlation between dance experience and any of the three jerk values. Conclusion: Our results showed that individuals with more dance experience performed the task more smoothly. This study suggests that dimensionless jerk should be used as a predictor for smoothness in dance movement. Thus, our results support the idea that smoothness is an aspect of movement quantity distinct from speed and distance.

• Korean Institute of Interior Design Journal
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• v.21 no.5
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• pp.343-354
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• 2012

Museums in Korea have experienced continuing quantitative growth since the late Choson Dynasty. However, a careful examination of visitors' viewing behavior has not been properly performed. Accordingly, social education for visitors in museums is not properly conducted despite the vast amount of information that museums possess. Given these circumstances, this study which focuses on the factors that influence visitors' behavior in museums intends to examine the effects that the configuration of exhibition space and the resulting visitor circulation patterns have on visitors' behavior with regard to visitor density. From this perspective, and considering five public historical museums within the seoul metropolitan area of korea, a correlation analysis has been conducted based upon quantitative analysis related to the configuration of exhibition space and visitors' observed viewing behaviors. The result of our study is that the configuration of exhibition space influences the patterns of visitor circulation, distribution of space, and the subsequent state of visitor density. Accordingly, the effects of visitor density on the viewing speed and other viewing behaviors could be identified. Based on these findings, the configurational differences in exhibition spaces were identified as one of the key factors that influence visitors' viewing behaviors.