• Title/Summary/Keyword: quantitative test

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Evaluation of Perfusion and Image Quality Changes by Reconstruction Methods in 13N-Ammonia Myocardial Perfusion PET/CT (13N-암모니아 심근관류 PET/CT 검사 시 영상 재구성 방법에 따른 관류량 변화와 영상 평가)

  • Do, Yong Ho;Lee, Hong Jae;Kim, Jin Eui
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.69-75
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    • 2014
  • Purpose: The aim of this study was to evaluate changes of quantitative and semi-quantitative myocardial perfusion indices and image quality by image reconstruction methods in $^{13}N$-ammonia ($^{13}N-NH_3$) myocardial perfusion PET/CT. Materials and Methods: Data of 14 (8 men, 6 women) patients underwent rest and adenosine stress $^{13}N-NH_3$ PET/CT (Biograph TruePoint 40 with TrueV, Siemens) were collected. Listmode scans were acquired for 10 minutes by injecting 370MBq of $^{13}N-NH_3$. Dynamic and static reconstruction was performed by use of FBP, iterative2D (2D), iterative3D (3D) and iterative TrueX (TrueX) algorithm. Coronary flow reserve (CFR) of dynamic reconstruction data, extent(%) and total perfusion deficit (TPD) (%) measured in sum of 4-10 minutes scan were evaluated by comparing with 2D method which was recommended by vendor. The image quality of each reconstructed data was compared and evaluated by five nuclear medicine physicians through a blind test. Results: CFR were lower in TrueX 18.68% (P=0.0002), FBP 4.35% (P=0.1243) and higher in 3D 7.91% (P<0.0001). As semi-quantitative values, extent and TPD of stress were higher in 3D 3.07%p (P=0.001), 2.36%p (P=0.0002), FBP 1.93%p (P=0.4275), 1.57%p (P=0.4595), TrueX 5.43%p (P=0.0003), 3.93%p (P<0.0001). Extent and TPD of rest were lower in FBP 0.86%p (P=0.1953), 0.57%p (P=0.2053) and higher in 3D 3.21%p (P=0.0006), 2.57%p (P=0.0001) and TrueX 5.36%p (P<0.0001), 4.36%p (P<0.0001). Based on the results of the blind test for image resolution and noise from the snapshot, 3D obtained the highest score, followed by 2D, TrueX and FBP. Conclusion: We found that quantitative and semi-quantitative myocardial perfusion values could be under- or over-estimated according to the reconstruction algorithm in $^{13}N-NH_3$ PET/CT. Therefore, proper dynamic and static reconstruction method should be established to provide accurate myocardial perfusion value.

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The Development and Evaluation of a Simple Semi-Quantitative Food Frequency Questionnaire Using the Contribution of Specific Foods to Absolute Intake and Between-Person Variation of Nutrient Consumption (영양소 섭취의 주요급원식품과 주요변이식품들을 이용한 간소화된 반정량 빈도 조사 도구의 개발 및 평가)

  • Kim, Mi-Yang;Suh, Il;Nam, Chung-Mo;Yoon, Jee-Young;Shim, Jee-Seon;Oh, Kyung-Won
    • Journal of Nutrition and Health
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    • v.35 no.2
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    • pp.250-262
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    • 2002
  • This study was conducted to develop a simple flood frequency questionnaire (FFQ) based on the results of contributions of specific floods to absolute intake and between-person variance in nutrients using semi-quantitative FFQ with 93 flood items. The subjects were 554 healthy adults for development of a simple FFQ, and 37 students for a validation test of a developed simple FFQ. The contribution of specific floods to 80% absolute nutrient intake was measured by assessing their percentage in total consumption of a nutrient. To assess the contributions of floods to the between-person variance in the intake of each specific nutrient, stepwise multiple regressions were performed. The number of floods necessary to account for the respective 80% of absolute intake was 11-36, depending on the nutrient, while flower floods (5-16 floods) were required for the corresponding percentage of between-person variation for all nutrients. Important floods for between-person variance include Tangsuyuk (pork) and snacks for energy and fat, fish for protein and polyunsaturated fatty acids (PUFA) and snacks for carbohydrates. Spearman correlation coefficients between 93-itemed FFQ and 63-itemed FFQ ranged from 0.91 for vitamin A to 0.99 for fat in the population data used in developing a simple FFQ. Also, the correlation coefficients between the two FFQs were 0.82-7.92 in the population for the validation test. This study suggests that useful information on dietary intake could be obtained using a simple semi-quantitative FFQ in a large-scale dietary survey in Korea.

Sex Differences in Bone Marrow Density Measured by Quantitative Ultrasonometry: For 20 year old college student (정량적 초음파 측정에 의한 골밀도의 남녀 차이: 20대 대학생 대상으로)

  • Lee, Won-Jeong
    • Journal of radiological science and technology
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    • v.40 no.3
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    • pp.401-405
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    • 2017
  • The Purpose of this study is to compare the bone marrow density measured by quantitative ultrasonometry (QUS) between men and women. Questionnaires for general characteristics were obtained from 104 participants, and then their both calcaneus was measured by using QUS. Sex differences for bone marrow density (BMD) were analyzed by an Independent t-test using the SPSS 19.0 program. Of 104 participants, women and men were 69(66.3%) and 35(33.7%), respectively. T-value of left calcaneus was high significantly in women than that in men(0.443 vs. 0.031, p=0.161) as well as that of right calcaneus(0.555 vs. 0.049, p=0.093). T-value of right calcaneus was high than that of left calcaneus in women and men (not significant, p>0.05). T-value of both calcaneus was increasing with physical activity. T-value of calcaneus was no statistically significant with age and body mass index. The BMD of women is high significantly more than that of men, and BMD is relation with physical activity.

Quantitative Damage Index of RC Columns with Non-seismic Details (비내진상세를 가지는 철근콘크리트 기둥의 정량적 손상도 평가 기준)

  • Kim, Kyung-Min;Oh, Sang-Hoon;Choi, Kwang-Yong;Lee, Jung-Han;Park, Byung-Cheol
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.17 no.6
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    • pp.11-20
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    • 2013
  • In this paper, the quantitative damage index for reinforced concrete (RC) columns with non-seismic details were presented. They are necessary to carry out the postearthquake safety evaluation of RC buildings under 5 stories without seismic details. The static cyclic test of the RC frame sub-assemblage that was an one span and actual-sized was first conducted. The specimen collapsed by the shear failure after flexural yielding of a column, lots of cracks on the surfaces of columns and beam-column joints and the cover concrete splitting at the bottom of columns occurred. The damage levels of these kinds of columns with non-seismic details were classified to five based on the load-displacement relationship by the test result. The residual story drift ratios and crack widths were then adapted as the quantitative index to evaluate the damage limit states because those values were comparatively easy to measure right after earthquakes. The highest one among the residual story drift ratios under the similar maximum story drift ratio decided on the residual story drift ratio of each damage limit state. On the other hand, the lowest and average ones among the respective residual shear and flexural widths under the similar maximum story drift ratio decided on the residual shear and flexural widths of each damage limit state, respectively. These values for each damage limit state resulted in being smaller than those by the international damage evaluation guidelines that are for seismically designed members under the same deformations.

Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA (OC Sensor PLEDIA를 이용한 LX Detergent Cleaning Solution과 OC Detergent Cleaning Solution의 동등성 평가)

  • Cha, Kyung Jae
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.1
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    • pp.19-31
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    • 2021
  • This study aimed at comparing the performance of imported LX detergent cleaning solution (LX-CS) and the self-manufactured OC cleaning solution (OC-CS), based on functional and quantitative analysis. The functional analysis was carried out using apparent diffusion coefficient (ADC) values. For quantitative analysis, precision, linearity, and carry-over rates were measured with commercial control materials according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Using OC-Sensor PLEDIA (Eiken Chemical, Japan), the ADC value of all cuvettes satisfied the acceptance criteria. For quantitative analysis, precision was less than 5.0% for the two products, and carry-over rates were less than ±1.00%. The linearity slopes and r2 values were 1.0017 and 0.9982 in the LX-CS, and 0.9924 and 0.9996 in the OC-CS, respectively. The correlation coefficient (r) was found to be 0.9997. Also, the percent difference in correlation with 40 artificial-stool specimens was less than 10% and the p-value was less than 0.1. The result of standard deviation ratio (D: ±1 SD ratio) was similar for both products. In conclusion, the functional and quantitative analyses of the two products were compared and showed similar results. In the future, the self-manufactured OC-CS will be able to provide a much more stable and faster supply than the imported LX-CS.

Effect of Punch Design and Friction Condition on Deformation Pattern in Boss and Rib Test (보스-리브 시험 시 펀치 형상 및 마찰 조건에 따른 변형 양상에 대한 연구)

  • Yun, Y.W.;Kang, S.H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2009.10a
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    • pp.332-337
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    • 2009
  • Recently, boss and rib test based on backward extrusion process was proposed to quantitative evaluate the interfacial friction condition in bulk forming process. In this test, the tube-shaped punch with hole pressurizes the workpiece so that the boss and rib are formed along the hole and outer surface of the punch. It was experimentally and numerically revealed that the height of boss is higher than that of the rib under the severe friction condition. This work is focused on the effect of the punch design and friction condition on deformation pattern in boss and rib test. From the boss and rib test simulations, it was found that there is slight variation in both the heights of boss and rib according to the length of punch land, nose radius, and face angle. However the hole diameter of the punch and the clearance between the punch and die have a significant influence on the heights of the boss and rib. In addition, the effect of flow stress was also investigated on the deformation patterns through FE simulations.

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A Study on the Mechanical Properties of Butt Welding Zone of Clad Steel According to the Process Design (공정 디자인에 따른 클래드강 맞대기 용접부의 기계적 특성에 관한 연구)

  • Lee, Jung-Hyun;Park, Jae-Won
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.21 no.4
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    • pp.532-540
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    • 2012
  • In this study, some considerations have been suggested in developing on-site techniques to evaluate the sensitization of stainless steels. Electrochemical potentiokinetic reactivation (EPR) technique is known to be a candidate tool for field applications since it enables quantitative assessment in reasonable test time, compared to oxalic etching (ditch) technique. The on-site application of the test method imposes additional restrictions on the selection of the test method (for example, minimum surface preparation requirement, insensitivity to testing temperature, etc.). The EPR and etching techniques have been compared in order to sensitization of stainless steel structures. It has been widely reported that the maximum sensitivity in the welded structure of stainless steel is shown at heat-affected zone (HAZ) than weldments with cast structure. In this work, sectioned weldments and external surfaces were investigated to reveal the degree of sensitization by the etching and the results were compared with those of EPR test. The EPR test showed little sensitivity to surface roughness and test temperature.

A Study on Small Punch-Creep Test Using Finite Element Analysis II (유한요소해석을 이용한 소형펀치-크리프 시험에 관한 연구 (II) - SP-Creep 시험과 일축 크리프 시험의 상관성을 중심으로 -)

  • Lee, Song-In;Kwon, Il-Hyun;Kim, Yon-Jig;Ahn, Byung-Guk;Ahn, Haeng-Keun;Baek, Seung-Se;Yu, Hyo-Sun
    • Proceedings of the KSME Conference
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    • 2001.11a
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    • pp.111-116
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    • 2001
  • Small punch-creep(SP-Creep) test technique has been applied for evaluating the creep characteristics for high temperature materials. However, in order to evaluate the damage and predict the remaining life, it is necessary to establish a quantitative correlation between SP-Creep and uniaxial-creep test results. This paper presents analytical and experimental results of useful correlation between SP-Creep and uniaxial-creep properties for 9Cr1MoVNb steel at $600{\sim}650^{\circ}C$ in terms of stress(load) and activation energy during creep deformation. Especially, the activation energy obtained from SP-Creep test is linearly related to that from uniaxial-creep test at $650^{\circ}C$ as follows: $Q_{sp-p}{\fallingdotseq}1.37\;Q_{TEN},\;Q_{sp-{\sigma}}{\fallingdotseq}1.53\;Q_{TEN}$.

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Improved Performance Evaluation Method for EUT in Power Frequency Magnetic Field Immunity Test (전원주파수 자계 내성시험의 개선된 EUT 성능평가방법)

  • 정기범;최재훈
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.8
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    • pp.796-802
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    • 2003
  • In this paper, an improved EUT(Equipment Under Test) evaluation method using image monitor for power frequency magnetic field immunity test was proposed and development of an automated real time image monitoring program was described. The proposed power frequence magnetic field immunity test detects automatically the change between the affected and unaffected image of EUT under the influence of electromagnetic wave. The proposed method for real time decision supplements shortcomings of the currently used method which is subjective to tester´s decision by ensuring the repeatability of the test. The change detection of EUT image provides a possibility of the immunity decision for PC monitors. In addition, the method to draw quantitative value in EUT immunity decision is suggested in accordance with the international standards and domestic trends.

Comparison of QSAR mutagenicity prediction data with Ames test results (Ames test 결과와 QSAR을 이용한 변이원성예측치와의 비교)

  • 양숙영;맹승희;이종윤;이용욱;정호근;정해원;유일재
    • Environmental Mutagens and Carcinogens
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    • v.20 no.1
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    • pp.21-25
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    • 2000
  • Recently there is increasing interest in the use of structure activity relationships for predicting the biological activity of chemicals. The reasons for the interest include the decrease cost and time per chemical as compared with animal or cell system for identifying toxicological effects of chemicals and the reduction in the use of animals for toxicological testing. This study is to test the validity of the mutagenicity data generated from QSAR (Quantitative Structure Activity Relationship) program. Thirty chemicals, which had been evaluated by Ames test during 1997-1999, were assessed with TOPKAT QSAR mutagenicity prediction module. Among 30chemicals experimented, 28 were negative and 2 were positive for Ames test. On the contrary, 23 chemicals showed the high confidence level indicating high prediction rate in mutagenicity evaluation, and 7 chemicals showed the lsow to moderate confidence level indicating low prediction in mutagenicity evaluation. Overall mutagenicity prediction rate was 77% (23/30). The prediction rates for non-mutagenic chemicals were 79% (22/28) and mutagenic chemicals were 50% (1/2). QSAR could be a useful tool in providing toxicological data for newly introduced chemicals or in furnishing data for MSDS or in determining the dose in toxicity testing for chemicals with no known toxicological data.