• Journal of The Korean Astronomical Society
• /
• v.26 no.1
• /
• pp.33-45
• /
• 1993

We have conducted surface photometry of a spiral galaxy NGC4419, by making use of photographic plates in U, B, V and R-bands taken by 105cm Schmidt Camera at Kiso Observatory. Two dimensional surface brightness distributions as well as luminosity profiles along the major axis are examined in detail to decipher the morphological properties of the galaxy. Analysis of the color distributions of NGC4419 shows that B-V and U-B colors remain constant throughout the galaxy with a weak trend of blue bulge in B-V color. The blue bulge might indicate an active star formation in the nucleus of NGC4419. For a quantitative analysis of the luminosity distribution of NGC4419, the observed luminosity profiles are decomposed into bulge and disk components, assuming the bulge component to follow de Vaucouleurs $\gamma^{1/4}-law$ while the disk component is assumed to be exponential. The fitting generally fails at the central part and at the shoulder near r = 15' where bulge and disk components overlap. The failure at the central part cannot be attributed wholly by the seeing disk since the core-radius of the central plateau is much larger than the width of point spread function. The failure at shoulder could be due to the luminosities from the spiral arms.

• 한국가시화정보학회:학술대회논문집
• /
• 2002.11a
• /
• pp.39-42
• /
• 2002

In the current study, characteristics of the laser-induced plasma were investigated in a gas filled chamber or in a gas jet by using a relatively low intensity laser $(I\;\leq\;5\;\times\;10^{12}\;W/cm^2)$. Temporal evolutions of the produced plasma were measured using the shadow visualization and the shock wave propagation as well as the electron density profiles in the plasma channel was measured using the Mach-Zehnder interferometry. Experimental results such as the structure of the produced plasma, shock propagation speed $(V_s)$, electron density profiles $(n_e)$, and the electron temperature $(T_e)$ are discussed in this study. Since the diagnostic laser pulse occurs over short time intervals compared to the hydrodynamic time scales of expanding plasma or a gas jet, all the transient motion occurring during the measurement is assumed to be essentially frozen. Therefore, temporally well-resolved quantitative measurements were possible in this study.

• 대한예방의학회:학술대회논문집
• /
• 1994.02a
• /
• pp.405-411
• /
• 1994

Hazardous wastes released into the general environment are of concern to the public and to public health authorities. In response to this concern, the Comprehensive Environmental Response, Compensation, and Liability Act, as amended (commonly called Superfund), was enacted in 1980 to provide a framework for environmental, public health, and legal actions concerning uncontrolled releases of hazardous substances. The Agency for Toxic Substances and Disease Registry (ATSDR) was created by Superfund to address the public health issues of hazardous wastes in the community environment. Two key Agency programs, Public Health Assessments and Toxicological Profiles, are designed to assess the risk to human health of exposures to hazardous substances that migrate from waste sites or through emergency releases (e.g., chemical spills). The Agency's public health assessment is a structured process that permits ATSDR to identify which waste sites or other point sources require traditional public health actions (e.g.. human exposure studies, health studies, registries, health surveillance, health advisories). The ATSDR qualitative public health assessment complements the U.S. Environmental Protection Agency's quantitative risk assessment. For Superfund purposes, both assessments are sitespecific. ATSDR's toxicological profiles are prepared for priority hazardous substances found most frequently at Superfund sites. Each profile presents the current toxicologic and human health effects information about the substance being profiled. Each profile also contains Minimal Risk Levels (MRLs), a type of risk assessment value. This paper covers ATSDR's experience in conducting public health assessments and developing MRLs, and it relates this experience to recommendations on how to improve chemical risk assessments.

• Journal of Pharmacopuncture
• /
• v.16 no.3
• /
• pp.30-38
• /
• 2013

Objectives: Modified regular ginseng extract (MRGX) has stronger anti-cancer activity-possessing gensenoside profiles. Methods: To investigate changes in gene expression in the MRGX-treated lung cancer cells (A549), we examined genomic data with cDNA microarray results. After completing the gene-ontology-based analysis, we grouped the genes into up-and down-regulated profiles and into ontology-related regulated genes and proteins through their interaction network. Results: One hundred nine proteins that were up- and down-regulated by MRGX were queried by using IPA. IL8, MMP7 and PLAUR and were found to play a major role in the anti-cancer activity in MRGX-treated lung cancer cells. These results were validated using a Western blot analysis and a semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) analysis. Conclusions: Most MRGX-responsive genes are up-regulated transiently in A549 cells, but down-regulated in a sustained manner in lung cancer cells.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.34 no.4
• /
• pp.305-310
• /
• 2014

In this study, a non-destructive evaluation (NDE) mothod is proposed for ball bearings contaminated with micro foreign substances, which were inserted into a ball bearing to create a defective specimen. The non-contact quantitative infrared thermographic technique was applied for NDE condition monitoring. Passive thermographic experiments were conducted to perform early fault diagnosis, for bearings operated at optimized torque status under a dynamic load condition. The temperature profiles for normal and defective specimens were quantitatively compared, and the thermographic data analyzed. Based on the NDE results, the temperature characteristics and abnormal fault detection of the ball bearing were quantitatively analyzed according to the rise in temperature.

• BMB Reports
• /
• v.41 no.4
• /
• pp.322-327
• /
• 2008

In this study, we compared the gene expression profiles of non-syndromic hyperplastic dental follicle (HDF) fibroblasts and normal dental follicle (NDF) fibroblasts using cDNA micro-arrays, quantitative PCR, and immunohistochemical staining. Microarray analysis showed that several collagens genes were upregulated in the HDF's, including collagen types I, IV, VIII, and XI and TIMP-1, -3, and -4 (fold ratio > 2.0). In contrast, the expression of MMP-1, -3, -10, and -16 together with IL-8 was more than two fold downregulated. The differential expression of the genes encoding alkaline phosphatase, MMP-1, -3, -8, and IL-8 was confirmed by quantitative RT-PCR, while that of 24 HDFs and 18 NDFs was confirmed by immunohistochemical analysis. However, HDFs showed stronger expression of MMP-3 than NDFs (P < 0.001). Collectively, these results indicate that defective regulation of MMPs mediating connective tissue remodeling may be responsible for abnormal tooth eruption.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.23 no.11 s.170
• /
• pp.1878-1885
• /
• 1999

Ultrasonic technique which is one of the most common nondestructive evaluation techniques has been applied to evaluate the integrity of structures by analyzing the characteristic of scattering sign al from internal defects. Therefore, a numerical analysis of ultrasonic scattering field due to defect profiles is absolutely needed for the accurate, quantitative estimation of internal defects. In this paper, the SH-wave scattering by multi-cavity defects and inclusion using Elastodynamic Boundary Element Method is studied. The effects of shape and distance of defects on transmitted and reflected fields are considered. The interaction of multi-cavity defects in SH-wave scattering is also investigated. Numerical calculations by the BEM have been carried out to predict near field solution of scattered fields of ultrasonic SH-wave. The presented results can be used to improve the detection sensitivity and pursue quantitative nondestructive evaluation for inverse problem.

• Genomics & Informatics
• /
• v.8 no.1
• /
• pp.34-40
• /
• 2010

Radiofrequency (RF) radiation might induce the transcription of a certain set of genes as other physical stresses like ionizing radiation and UV. To observe transcriptional changes upon RF radiation, we exposed WI-38, human lung fibroblast cell to 1763 MHz of mobile phone RF radiation at 60 W/kg of specific absorption rate (SAR) for 24h with or without heat control. There were no significant changes in cell numbers and morphology after exposure to RF radiation. Using quantitative RT-PCR, we checked the expression of three heat shock protein (HSP) (HSPA1A, HSPA6 and HSP105) and seven stress-related genes (TNFRSF11B, FGF2, TGFB2, ITGA2, BRIP1, EXO1, and MCM10) in RF only and RF/HS groups of RF-exposed cells. The expressions of three heat shock proteins and seven stress-related genes were selectively changed only in RF/HS groups. Based on the expression of ten genes, we could classify thermal and non-thermal effect of RF-exposure, which genes can be used as biomarkers for RF radiation exposure.

• Journal of the Korean Society of Food Culture
• /
• v.31 no.1
• /
• pp.105-110
• /
• 2016

The objective of this study was to determine sensory profiles of rice confections. The samples used in this study obtained from Korea (traditional Korea rice snack and local specialty rice snack) and three countries (USA, Japan, and China) were evaluated and compared. The sensory characteristics of five kinds of rice confections were evaluated using a sensory test and were analyzed via quantitative description analysis (QDA), principal component analysis (PCA), and hierarchical cluster analysis (HCA). In the descriptive analysis, 10 trained panelists evaluated sensory characteristics consisting of 19 attributes, and there were significant differences (p<0.05) among the 16 characteristics. For the descriptive data, multivariate analysis of variance was carried out and identified differences among the samples. The PCA of rice confections for the first two principal components could explain 85.66% of the variations. The Korean, Japanese, and Chinese rice confections were savory, gritty, and particle-sized, the other Korean local specialty rice confections were fruity, sweet, honey-flavored, compact, and crispy, and those from the USA were glossy, grainy, bright, adhesive, cohesive, crispy, and sweet.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2012.02a
• /
• pp.275-275
• /
• 2012

The relative composition of $Cu(InGa)Se_2$ solar cells is one of the most important measurement issues. However, quantitative analysis of multi-component alloy films is difficult by surface analysis methods due to severe matrix effect. In this study, quantitative depth profiling analysis of CIGS films was investigated by secondary ion mass spectrometry (SIMS). The compositions were measured by SIMS using the alloy reference relative sensitivity factors derived from the certified compositions and the total counting numbers of each element. The compositions measured by SIMS were linearly proportional to those by inductively coupled plasma-mass spectrometry (ICP-MS) using isotope dilution method. In this study, the quantification measured by ICP-MS method is compared with the composition calculated by SIMS depth profiles with AR-RSFs obtained from the reference. The SIMS depth profile of CIGS thin films according to the manufacturing condition was converted into compositional depth profile.