• Title/Summary/Keyword: quality control (QC)

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Improvement of the Result Related to Tumor Marker Test Through the OCS QC Program (OCS QC 프로그램을 통한 건진 센터 종양검사의 결과보고 개선)

  • Back, Song-Ran;Kim, Sung-Ho;Yoo, So-Yeon;Kim, Nyun-Ok;Moon, Hyoung-Ho;Yoo, Seon-Hee;Cho, Shee-Man
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.3
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    • pp.185-188
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    • 2009
  • Purpose: Standard of retests were discrepant and inconsistent due to inaccuracy and lack of standardization within normal range limit of tumor marker test. To enhance the standardization of retests set standard value below normal range and the Order Communication System Quality Control (OCS QC) program was put in place. This program enables managing the results within lower limit of normal range which were used for tumor marker test in Health Center. Materials and Methods: At present the tumor marker study for AFP, CEA, CA19-9, CA125, and PSA included outpatients in Asan Medical Center from February to March, 2009. The standard value was obtained by using the percentage of CV of Inter Assay according to the normal range of each tumor test. The results were confirmed by using the OCS QC program via formatted assessment of screening test such as test items, standard value and medical department. The number of out-of-range results within plus and minus 30 percents regarding the five primary items of tumor marker test was assessed. The next step was to obtain the number of AFP, CEA, and CA125 according to the ratio of comparison between prior and post test result, 60%, 50%, and 40% within normal range, respectively. In addition, set standard value below normal range. Results: The first screening test with percentage of sample number was resulted between 30%-40% and the second one was AFP 26.1%, CEA 18.9%, CA19-9 17.3%, CA125 18.7%, and PSA 21.0% obtained screening percentage of average 20 percents. The limited value of retest was AFP less than 5.0 and more than 10.0, CEA less than 1.0 and more than 3.0, CA19-9 less than 10.0 and more than 30.0, and PSA less than 1.0 and more than 2.0 to set and the number of retest was obtained by applying to the limited value of retest to screening percentage of average 20 percents For two months, the number of retest was AFP 0, CEA 15, CA19-9 3, CA125 2, and PSA 5. Conclusions: Through using the OCS QC program in establishing the standard of retest systemically, there appeared to be reduced discrepancy among the examiners and to be expected improvement in relation to the error of results.

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Evaluation of International Quality Control Procedures for Detecting Outliers in Water Temperature Time-series at Ieodo Ocean Research Station (이어도 해양과학기지 수온 시계열 자료의 이상값 검출을 위한 국제 품질검사의 성능 평가)

  • Min, Yongchim;Jun, Hyunjung;Jeong, Jin-Yong;Park, Sung-Hwan;Lee, Jaeik;Jeong, Jeongmin;Min, Inki;Kim, Yong Sun
    • Ocean and Polar Research
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    • v.43 no.4
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    • pp.229-243
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    • 2021
  • Quality control (QC) to process observed time series has become more critical as the types and amount of observed data have increased along with the development of ocean observing sensors and communication technology. International ocean observing institutions have developed and operated automatic QC procedures for these observed time series. In this study, the performance of automated QC procedures proposed by U.S. IOOS (Integrated Ocean Observing System), NDBC (National Data Buy Center), and OOI (Ocean Observatory Initiative) were evaluated for observed time-series particularly from the Yellow and East China Seas by taking advantage of a confusion matrix. We focused on detecting additive outliers (AO) and temporary change outliers (TCO) based on ocean temperature observation from the Ieodo Ocean Research Station (I-ORS) in 2013. Our results present that the IOOS variability check procedure tends to classify normal data as AO or TCO. The NDBC variability check tracks outliers well but also tends to classify a lot of normal data as abnormal, particularly in the case of rapidly fluctuating time-series. The OOI procedure seems to detect the AO and TCO most effectively and the rate of classifying normal data as abnormal is also the lowest among the international checks. However, all three checks need additional scrutiny because they often fail to classify outliers when intermittent observations are performed or as a result of systematic errors, as well as tending to classify normal data as outliers in the case where there is abrupt change in the observed data due to a sensor being located within a sharp boundary between two water masses, which is a common feature in shallow water observations. Therefore, this study underlines the necessity of developing a new QC algorithm for time-series occurring in a shallow sea.

Quality Control System for Analytical Chemistry Laboratory of Pesticide Products (농약 이화학시험 분석기관 정도관리체계)

  • Chang, Hee-Ra;Lee, Joon-Yeob;Lee, Young-Ju;Kang, Hye-Rim;Kim, Chan-Sub;Kim, Kyun
    • The Korean Journal of Pesticide Science
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    • v.15 no.4
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    • pp.529-544
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    • 2011
  • Many international organizations, such as the International Organization for Standardization (ISO) and Collaborative International Pesticide Analytical Council (CIPAC), have published a guide to quality control requirements, proficiency testing and method validation for pesticide formulation. In general, proficiency testing is to determine the performance of individual laboratories from the comparison of test results and to monitor a laboratory's performance abilities. One of quality assurance (QA) scheme would be include the validation of analytical method that implies a performance characteristics, specificity, selectivity, linearity and so on. According to many international organizations, the quantification methods of active substance in formulated pesticide products are required to be reproducible, accurate and precise. This study was conducted to compare the international guidelines for the quality control, proficiency testing and method validation of analytical laboratories and to propose a general guidance for the establishment of quality control system in the analytical chemistry laboratories of pesticide formulation in domestic.

Efforts on Improving Comparability of Ocean Chemical Data (해양 화학 자료 상호비교성 향상을 위한 노력)

  • RHO, TAEKEUN
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.3
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    • pp.201-219
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    • 2021
  • Recently, in order to understand the role of the ocean in global problems such as climate change, various researchers have made efforts to integrate and systematically manage the data collected from the world's oceans over the past half century. In Korea, public institutions, research institutes, and universities are carrying out efforts to continuously monitor changes in the marine environment in the waters surrounding Korea. The various types of marine chemical data produced in this way have been independently managed according to the purpose of each institution. Recently, efforts are being made to integrate various data led by the state. In this study, the data quality management method used to systematically manage the data of various types produced by various institutions abroad was explained. In this study, by applying this method, the format of data produced by various domestic institutions is unified, primary quality control of data according to oceanographic characteristics, secondary quality control using reliable data and comparison or standard materials, etc. It aims to provide basic information for carrying out these processes, and ultimately contribute to integrating data collected for various purposes in Korea into a data set that can be compared with each other regardless of the proficiency of producers.

Development of a Flood Runoff and Inundation Analysis System Associated With 2-D Rainfall Data Generated Using Radar I. Quality Control and CAPPI Composite Calculation (레이더 정량강우와 연계한 홍수유출 및 범람해석 시스템 확립 I. 품질검사와 합성 CAPPI 산출)

  • Choi, Kyu-Hyun;Han, Kun-Yeun;Kim, Kyung-Eak;Lee, Chang-Hee
    • Journal of Korea Water Resources Association
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    • v.39 no.4 s.165
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    • pp.321-334
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    • 2006
  • The need for economical and accurate presentations of equivalent radar reflectivity( $Z_e$) data in an orthogonal coordinate system has existed for some time. So, in this study, a fast and efficient procedure has been developed which allows the systematic interpolation of digital reflectivity data from radar space into Cartesian space. At first, QC(Quality Control) of radar data has been executed for extracting uncontaminated Constant Altitude Plan Position Indicator(CAPPI) data. The algorithm is designed so that only one ordered pass through the original Plan Position Indicator(PPI) scan data is necessary to complete the interpolation process. The model can calculate various resolution and altitude reflectivity data for many kinds of hydrological usage.

Sample Development for Quality Control of Formaldehyde and Proficiency Analytical Testing (정도관리용 포름알데히드 시료개발 및 분석능력평가)

  • Park, Hae Dong;Jang, Miyeon;Park, Seunghyun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.30 no.1
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    • pp.58-66
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    • 2020
  • Objectives: The objective of this study was to develop formaldehyde samples for quality control (QC) and to test the applicability of proficiency analytical testing in Korea. Methods: We made formaldehyde samples with certified standard solutions (formaldehyde in water or acetonitrile) and 2,4-dinitrophenylhydrazine (2,4-DNPH)-coated silicagel tubes. Four levels of formaldehyde concentration were tested for storage stability at room temperature and at 4℃ over three months. Analytical proficiency testing was performed with four or 36 institutes. Results: Formaldehyde sample tubes were easily made through the injection of standard solutions and the average efficiencies of recovery were 95-101%. The coefficients of variation (CV) of the formaldehyde samples were 1.39-2.55%. The recovery efficiencies fell between 90% and 110% at the concentration range of 1-10 ㎍/sample over three months storage at refrigerated and room temperature. The CVs were less than 5% in the proficiency analytical testing. By adjusted proficient ranges, 64% of the results of the second proficiency analytical testing were acceptable. Conclusions: The formaldehyde samples made by injection on 2,4-DNPH-coated silicagel tubes were stable and applicable for quality control.

Application of Quality Statistical Techniques Based on the Review and the Interpretation of Medical Decision Metrics (의학적 의사결정 지표의 고찰 및 해석에 기초한 품질통계기법의 적용)

  • Choi, Sungwoon
    • Journal of the Korea Safety Management & Science
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    • v.15 no.2
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    • pp.243-253
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    • 2013
  • This research paper introduces the application and implementation of medical decision metrics that classifies medical decision-making into four different metrics using statistical diagnostic tools, such as confusion matrix, normal distribution, Bayesian prediction and Receiver Operating Curve(ROC). In this study, the metrics are developed based on cross-section study, cohort study and case-control study done by systematic literature review and reformulated the structure of type I error, type II error, confidence level and power of detection. The study proposed implementation strategies for 10 quality improvement activities via 14 medical decision metrics which consider specificity and sensitivity in terms of ${\alpha}$ and ${\beta}$. Examples of ROC implication are depicted in this paper with a useful guidelines to implement a continuous quality improvement, not only in a variable acceptance sampling in Quality Control(QC) but also in a supplier grading score chart in Supplier Chain Management(SCM) quality. This research paper is the first to apply and implement medical decision-making tools as quality improvement activities. These proposed models will help quality practitioners to enhance the process and product quality level.

템플릿에 기반한 객체 지향 탄성파 자료 처리 시스템

  • 김남윤;이두성;최재경
    • 한국지구물리탐사학회:학술대회논문집
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    • 2004.06a
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    • pp.88-93
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    • 2004
  • 본 논문에서는 현장에서 획득한 2차원 탄성파 탐사 자료를 처리하는 시스템을 제안한다. 일반적으로 탐사 자료는 매우 방대하여 효율적인 자료 처리 및 관리 시스템은 필수적이라고 할 수 있다. 본 논문에서는 모듈의 처리 과정에서 QC(Quality of Control)를 쉽게 하기 위해 윈도우 기반 GUI 환경을 제공할 뿐만 아니라, 모듈의 처리 흐름과 파라미터를 저장할 수 있는 템플릿 개념을 소개한다. 또한 객체 지향 개념을 도입하여 모듈들의 삽입, 삭제가 용이한 장점을 가지고 있다. 개발 환경은 MFC를 바탕으로 Windows 운영체제에서 개발되었다. 본 논문에서 개발된 시스템은 탄성파를 이용한 지반 조사에 효율적으로 사용될 수 있다고 사료된다.

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Present Status of the Quality Assurance and Control (QA/QC) for Korean Macrozoobenthic Biological Data and Suggestions for its Improvement (해양저서동물의 정량적 자료에 대한 정도관리 현실과 개선안)

  • CHOI, JIN-WOO;KHIM, JONG SEONG;SONG, SUNG JOON;RYU, JONGSEONG;KWON, BONG-OH
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.3
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    • pp.263-276
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    • 2021
  • Marine benthic organisms have been used as the indicators for the environment assessment and recently considered as a very important component in the biodiversity and ecosystem restoration. In Korean waters, the quantitative data on marine benthos was used as one of major components for the marine pollution assessment for 50 years since 1970s. The species identification which is an important factor for the quantitative biological data was mainly performed by the marine benthic ecologists. This leads to the deterioration of the data quality on marine benthos from the misidentication of major taxonomic groups due to the lack of taxonomic expertise in Korea. This taxonomic problem has not been solved until now and remains in most data from national research projects on the marine ecosystems in Korean waters. Here we introduce the quality assurance and control (QA/QC) system for the marine biological data in UK, that is, NMBAQC (Northeast Atlantic Marine Biological Analytic and Quality Control) Scheme which has been performed by private companies to solve similar species identification problems in UK. This scheme asks for all marine laboratories which want to participate to any national monitoring programs in UK to keep their identification potency at high level by the internal quality assurance systems and provides a series of taxonomic workshops and literature to increase their capability. They also performs the external quality control for the marine laboratories by performing the Ring Test using standard specimens on various faunal groups. In the case of Korea, there are few taxonomic expertise in two existing national institutions and so they can't solve the taxonomic problems in marine benthic fauna data. We would like to provide a few necessary suggestions to solve the taxonomic problems in Korean marine biological data in short-terms and long-terms: (1) the identification of all dominant species in marine biological data should be confirmed by taxonomic expertise, (2) all the national research programs should include taxonomic experts, and (3) establishing a private company, like the Korea marine organism identification association (KMOIA), which can perform the QA/QC system on the marine organisms and support all Korean marine laboratories by providing taxonomic literature and species identification workshops to enhance their potency. The last suggestion needs more efforts and time for the establishment of that taxonomic company by gathering the detailed contents and related opinions from diverse stakeholders in Korea.

Mountain Meteorology Data for Forest Disaster Prevention and Forest Management (산림재해 방지와 산림관리를 위한 산악기상정보)

  • Keunchang, Jang;Sunghyun, Min;Inhye, Kim;Junghwa, Chun;Myoungsoo, Won
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.24 no.4
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    • pp.346-352
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    • 2022
  • Mountain meteorology in South Korea that is covered mountains with complex terrain is important for understanding and managing the forest disaster and forest ecosystems. In particular, recent changes in dryness and/or rainfall intensity due to climate change may cause an increase in the possibility of forest disasters. Therefore, accurate monitoring of mountain meteorology is needed for efficient forest management. Korea Forest Service (KFS) is establishing the Automatic Mountain Meteorology Observation Stations (AMOS) in the mountain regions since 2012. 464 AMOSs are observing various meteorological variables such as air temperature, relative humidity, wind speed and direction, precipitation, soil temperature, and air pressure for every minute, which is conducted the quality control (QC) to retain data reliability. QC process includes the physical limit test, step test, internal consistency test, persistence test, climate range test, and median filter test. All of AMOS observations are open to use, which can be found from the Korean Mountain Meteorology Information System (KoMIS, http://mtweather.nifos.go.kr/) of the National Institute of Forest Science and the Public Data Portal (https://public.go.kr/). AMOS observations with guaranteed quality can be used in various forest fields including the public safety, forest recreation, forest leisure activities, etc., and can contribute to the advancement of forest science and technology. In this paper, a series of processes are introduced to collect and use the AMOS dataset in the mountain region in South Korea.