• 제목/요약/키워드: q-methodology

검색결과 634건 처리시간 0.033초

지역아동센터 운영자의 인식을 통해 본 지역아동센터의 기능과 역할 (Functions and Roles of Community Child Center Recognized by Practitioners)

  • 임정기;박현선;정익중
    • 한국사회복지학
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    • 제67권2호
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    • pp.285-310
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    • 2015
  • 본 논문은 우리나라 방과후 돌봄 체계의 중추적 역할을 하고 있는 지역아동센터의 고유한 기능과 역할에 대해 실무자들의 다양한 인식유형을 검증하기 위한 목적을 가진다. 이를 위하여 지역아동센터 실무자를 대상으로 시설 환경, 서비스 내용, 인력, 대상, 전달체계 측면으로 나누어 관련된 인식을 조사하였다. 분석결과 지역아동센터의 기능과 역할에 대한 인식유형은 '전문인력 중심의 통합서비스 지향형', '시설환경 기반의 보호서비스 지향형', '학교연계 방과후서비스 지향형', '개별맞춤형 기초사례서비스 지향형'으로 나눌 수 있었다. 이러한 결과는 또한 지역아동센터 실무자들이 지역아동센터의 발전을 위해 인력의 중요성과 서비스 환경에 대한 지원, 서비스 내용의 차별성과 연속성, 전체 돌봄체계와의 공통성과 독자성을 찾아갈 수 있는 기능 모색으로 다시 나눠지고 있었다. 본 연구는 지역아동센터의 기능과 역할에 대해 그동안 실증적으로 검증되지 못했던 다양한 인식내용의 실체를 파악해 보았다는데 의의가 있다. 이러한 결과를 통해 향후 지역아동센터의 기능과 역할에 대한 당사자들의 관점을 반영하고, 운영의 방향성에 대한 실천적 논의를 이끌어 낼 수 있을 것이며, 지역아동센터 모델과 운영에 대한 정책결정과 집행과정에 있어서 지원에 대한 구체적 방향성과 기초자료를 제공할 수 있을 것이다.

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새로운 2-(4-chloro-5-(2-chloroallyloxy)-2-fluorophenyl)-3-thioalkoxy-2,3,4,5,6,7-hexahydroisoindol-1-one 유도체들의 제초활성에 관한 분자 홀로그램(H) QSAR (Holographic Quantitative Structure-Activity Relationship (HQSAR) Analyses for the Herbicidal Activities of New Novel 2-(4-chloro-5-(2-chloroallyloxy)-2-fluorophenyl)-3-thioalkoxy-2,3,4,5,6,7-hexahydroisoindol-1-one Derivatives)

  • 성낙도;송종환;강은규;정훈성
    • 농약과학회지
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    • 제9권3호
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    • pp.199-204
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    • 2005
  • 일련의 새로운 2-(4-chloro-5-(2-chloroallyloxy)-2-fluorophenyl)-3-thioalkoxy-2,3,4,5,6,7-hexahydroisoindol-1-one 유도체들의 hexahydroisoindol-1-one 고리상 C3 원자에 결합된 R-치환기 변화에 따른 논피(Echinochloa crus-galli)에 대한 제초 활성과의 관계를 분자 홀로그램(H) QSAR 방법으로 연구하였다. 제초활성에 관한 HQSAR 모델(I-2)은 양호한 예측성($r^2_{cv.}$ 또는 $q^2=0.714$)과 상관성($r^2_{ncv.}=0.922$)을 나타내었다. 모델(I-2)의 기여도로부터 논피에 대한 기질 분자의 제초활성은 hexahyoisoindol-1-one 고리의 C4-C6 위치와 3-tolylthio group의 ortho-위치 탄소원자 및 meta-methyl group이 활성에 기여하였다.

작물학 분야 프로테오믹스의 응용과 전망 (Application and perspectives of proteomics in crop science fields)

  • 우선희
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2004년도 춘계 학술대회지
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    • pp.12-27
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    • 2004
  • Thanks to spectacular advances in the techniques for identifying proteins separated by two-dimensional electrophoresis and in methods for large-scale analysis of proteome variations, proteomics is becoming an essential methodology in various fields of plant sciences. Plant proteomics would be most useful when combined with other functional genomics tools and approaches. A combination of microarray and proteomics analysis will indicate whether gene regulation is controlled at the level of transcription or translation and protein accumulation. In this review, we described the catalogues of the rice proteome which were constructed in our program, and functional characterization of some of these proteins was discussed. Mass-spectrometry is a most prevalent technique to identify rapidly a large of proteins in proteome analysis. However, the conventional Western blotting/sequencing technique us still used in many laboratories. As a first step to efficiently construct protein data-file in proteome analysis of major cereals, we have analyzed the N-terminal sequences of 100 rice embryo proteins and 70 wheat spike proteins separated by two-dimensional electrophoresis. Edman degradation revealed the N-terminal peptide sequences of only 31 rice proteins and 47 wheat proteins, suggesting that the rest of separated protein spots are N-terminally blocked. To efficiently determine the internal sequence of blocked proteins, we have developed a modified Cleveland peptide mapping method. Using this above method, the internal sequences of all blocked rice proteins (i. e., 69 proteins) were determined. Among these 100 rice proteins, thirty were proteins for which homologous sequence in the rice genome database could be identified. However, the rest of the proteins lacked homologous proteins. This appears to be consistent with the fact that about 30% of total rice cDNA have been deposited in the database. Also, the major proteins involved in the growth and development of rice can be identified using the proteome approach. Some of these proteins, including a calcium-binding protein that fumed out to be calreticulin, gibberellin-binding protein, which is ribulose-1,5-bisphosphate carboxylase/oxygenase activate in rice, and leginsulin-binding protein in soybean have functions in the signal transduction pathway. Proteomics is well suited not only to determine interaction between pairs of proteins, but also to identify multisubunit complexes. Currently, a protein-protein interaction database for plant proteins (http://genome .c .kanazawa-u.ac.jp/Y2H)could be a very useful tool for the plant research community. Recently, we are separated proteins from grain filling and seed maturation in rice to perform ESI-Q-TOF/MS and MALDI-TOF/MS. This experiment shows a possibility to easily and rapidly identify a number of 2-DE separated proteins of rice by ESI-Q-TOF/MS and MALDI-TOF/MS. Therefore, the Information thus obtained from the plant proteome would be helpful in predicting the function of the unknown proteins and would be useful in the plant molecular breeding. Also, information from our study could provide a venue to plant breeder and molecular biologist to design their research strategies precisely.

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새로운 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenyl-propionamide 유도체들의 제초활성에 관한 HQSAR 모델과 높은 활성 화합물의 예측 (Molecular Holographic QSAR Model on the Herbicidal Activities of New Novel 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpropionamide Derivatives and Prediction of Higher Activity Compounds)

  • 성낙도;김대황;정훈성
    • 농약과학회지
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    • 제9권4호
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    • pp.279-286
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    • 2005
  • 일련의 새로운 기질 분자로서 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpropionamide 유도체들의 구조 변화와 그에 따른 발아 전, 논피 (Echinochloa crus-galli)에 대한 제초활성과의 분자 홀로그래피적(H) QSAR 관계를 연구하였다. 그 결과로부터 높은 제초활성 화합물들이 유도된 HQSAR 모델에 의하여 예측되었다. 가장 양호한 HQSAR 모델은 분자조각 크기($7{\sim}10bin$) 조건에서 유도된 모델(VI-1)이었다. 제초활성에 관한 HQSAR 모델(VI-1)은 높은 예측성($r^2_{cv.}$ 또는 $q^2=0.646$)과 상관성($r^2_{ncv.}=0.917$)에 근거하여 양호한 통계값들을 나타내었다. 그리고 HQSAR 기여도로부터 가장 낮은 제초활성은 4-(6-chloro-2-benzoxazolyloxy)phenoxy 고리($pred.pI_{50}=-3.20$)에 의존적이었다. 특히, (X)-phenoxy-N-(R)-phenylpropionamide 유도체의 R=4-fluoro, X=isobutoxy 치환체인 4-isobutoxyphenoxy-N-(4-fluorophenyl)propionamide (P2)는 가장 높은 제초활성($pred.pI_{50}=9.12$)을 나타내는 화합물로 예측되었다.

유통 상장기업의 현금정책에 관한 연구 (A Study on the Cash Policies of Retail Firms)

  • 손삼호
    • 유통과학연구
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    • 제13권3호
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    • pp.69-77
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    • 2015
  • Purpose - The purpose of this study is to examine whether the cash policies of retail firms listed on Korean stock markets are consistent with the evidence provided in the study of Almeida et al. (2004). Liquidity management is an important issue for financially constrained firms relative to financially unconstrained firms. Because there are few sources of external funding, the optimal liquidity policies of financially constrained firms should reflect their own earnings or cash inflows to create opportunities for current and future real investments. According to this simple idea, we estimate the sensitivity of cash to cash flows and simply check whether the estimated sensitivity to cash flows of the cash retained by constrained retail firms is greater than that of the cash retained by unconstrained retail firms. Through this work, we aim to explain why the cash policies of the retail firms listed on the Korean stock markets differ from those of listed manufacturing enterprises. Research design, data, and methodology - To explain a firm's cash holdings, we use only three explanatory variables: earnings before interest and taxes (EBIT), Tobin's q, and size. All the variables are defined as the value of the numerator divided by aggregate assets. Thanks to this definition, it is possible to treat all the sample firms as a single large firm. The sample financial data for this study are collected from the retail enterprises listed on the KOSPI and KOSDAQ markets from 1991 to 2013. We can obtain these data from WISEfn, the financial information company. This study's methodology has its origin in Keynes's simple idea of precautionary liquidity demand: When a firm faces financial constraints, cash savings from earnings or cash inflows become important from the corporate finance perspective. Following this simple idea, Almeida et al. (2004) developed their theoretical model and found empirical evidence that the sensitivity of cash to cash flows varies systematically according to different types of financing frictions. To find more empirical evidence for this idea, we examined the cash flow sensitivity of the cash held by Korean retail firms. Results - Through several robustness tests, we empirically showed that financially constrained Korean retail firms display significant positive propensity to save cash from earnings before interest and taxes, while the estimated cash flow sensitivity of the cash held by unconstrained retail firms is not significant. Despite the relatively low earnings of retail firms, their sensitivity is three times greater than that of manufacturing enterprises. This implies that Korean retail firms have greater intentions of facilitating future investments rather than current investments. Conclusions - The characteristics of the cash policies of Korean retail firms differ from those of manufacturing firms. This contrast may be attributable to industry-oriented policy planning, regulations, and institutional differences. However, the industrial policymakers should observe signals of the long-term growth options of retail firms based on their high propensity to save from their cash inflows.

공내재하시험을 이용한 화강풍화토의 전단계수 산정 (A Study on the Shear Modulus of Weathered Granite Soil by Pressuremeter Tests)

  • 김종수;이규환;이장덕;이송
    • 한국지반공학회지:지반
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    • 제13권6호
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    • pp.95-106
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    • 1997
  • 공내재하시험은 고무 튜브를 보링공에 넣어 압축을 가함으로써 압력과 변형관계 곡선을 얻을 수 있는데 지반교란이 해석 결과에 큰 영향을 미친다. 공내재하시험의 지배방정식은 공동확장이론과 쌍곡선 형태의 흙모델을 기본으로 이론적으로 유도할 수 있으며 이렇게 유도된 식과 곡선 보정기법을 적용시키면 지반교란이 없는 상태의 응력-변형 곡선을 얻을 수 있다. 이러한 해석 방법은 재하단계에 적용할 수 있으며 국내의 화강풍화토의 공내재하시험 결과에 적용하여 초기전 단계수를 구하였다. 이렇게 구한 초기전단계수값을 표준관입시험 결과와 비교 분석하여 초기전 단계수값과 표준관입시험의 상관관계를 구하였다.

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새로운 기법(技法)을 적용(適用)한 자연도(自然度) 평가(評價) (Assessment of Naturalness by Application of new Technique)

  • 이영근;이돈구;이병두
    • 한국산림과학회지
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    • 제90권4호
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    • pp.488-494
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    • 2001
  • 본 연구는 독일과 오스트리아 산림 Biotope 조사방법에 기초하여 한국에 맞는 산림 Biotope조사 방법을 개발하여 경기도 광주 태화산에 적용하였다. 조사는 교목층의 종조성과 연령에 따라 임분형을 구분하고 임분별로 자연도, 다양도를 5등급으로, 희귀도 여부를 평가하였다. 마지막으로 위의 세 요소를 더하여 종합평가를 하였다. 자연도는 해발 300m 이상의 신갈나무임분과 계곡임분이 4등급으로 구분되었고, 상수림나무임분과 상수리나무 굴참나무 혼합임분은 3등급으로 구분되었다. 사면하부의 조림지는 연령에 따라 1, 2등급으로 구분되었다. 다양도는 자연도와 비슷하였다. 그러나 일본잎깔나무 조림지의 경우 자연도는 1등급이었지만 다양도는 3등급이었다. 계곡부군락, 습지군락, 임연군락이 희귀군락으로 구분되었다. 종합평가도는 자연도와 비슷하였다. 이 방법은 녹지자연도에 비해 발전된 방법이며 계속 발전시킨다면 한국의 산림내 생물다양성보전에 기여할 것으로 기대된다.

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금연학교 입원프로그램 전과 후의 흡연자의 흡연에 대한 인식변화 (Changes in Smokers' Perception about smoking before and after Participation in a Hospitalized Smoking Cessation Program)

  • 장성옥;신성례;김흥규;김상숙;주은애
    • 대한간호학회지
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    • 제35권6호
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    • pp.1163-1173
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    • 2005
  • Purpose: This study was done to analyze the changes in smokers' subjectivity about smoking before and after participation in a 5-day hospitalized smoking cessation program. Design: Q-methodology, which provides a scientific method on subjectivity, was applied. Findings: Nine types of subjectivity changes about smoking were identified; Type I, Nicotine $craving{\to}Confident$ of self control for smoking; Type II, Nicotine $craving{\to}Cognition$ of the link between habituation and smoking, Type III, Nicotine craving ~ Nicotine craving, Type IV, smoking as a social $behavior{\to}Cognition$ of the link between habituation and smoking, Type V, smoking as a social $behavior{\to}Motive$ to turn away from being addicted to smoking to being healthy, Type VI, Habitual $smoking{\to}Confident$ of self control for smoking, Type VII, Habitual $smoking{\to}Cognition$ of the link between habituation and smoking, Type VIII, Habitual $smoking{\to}Motive$ to turn away from being addicted to smoking to being healthy and Type IX, Denial of the negative effects of $smoking{\to}Confident$ of self control for smoking Conclusion: The types of changes in smokers' subjectivity before and after the smoking cessation program in this study suggest a better tailored intervention for individual smokers. The types of changes on smokers' subjectivity provide insight about which factors of the interventions for smoking cessation are especially valued for a particular group of smokers.

RESEARCH ON MODULARIZED DESIGN AND PERFORMANCE ASSESSMENT BASED ON MULTI-DRIVER OFF-ROAD VEHICLE DRIVING-LINE

  • Yi, J.J.;Yu, B.;Hu, D.Q.;Li, C.G.
    • International Journal of Automotive Technology
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    • 제8권3호
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    • pp.375-382
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    • 2007
  • The multi-driver off-road vehicle drive-line consists of many components, with close connections among them. In order to design and analyze the drive-line efficiently, a modular methodology should be taken. The aim of a modular approach to the modeling of complex systems is to support behavior analysis and simulation in an iterative and thus complex engineering process, by using encapsulated submodels of components and of their interfaces. Multi-driver off-road vehicles are comparatively complicated. The driving-line is an important core part to the vehicle, it has a significant contribution to the performance. Multi-driver off-road vehicles have complex driving-lines, so performance is heavily dependent on the driving-line. A typical off-road vehicle's driving-line system consists of a torque converter, transmission, transfer case and driving-axles, which transfers the power generated by the engine and distributes it effectively to the driving wheels according to the road condition. According to its main function, this paper proposes a modularized approach for design and evaluation of the vehicle's driving-line. It can be used to effectively estimate the performance of the driving-line during the concept design stage. Through an appropriate analysis and assessment method, an optimal design can be reached. This method has been applied to practical vehicle design, it can improve the design efficiency and is convenient to assess and validate the performance of a vehicle, especially of multi-driver off-road vehicles.

Optimization of uranium biosorption in solutions by Sargassum boveanum using RSM method

  • Hashemi, Nooshin;Dabbagh, Reza;Noroozi, Mostafa;Baradaran, Sama
    • Advances in environmental research
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    • 제9권1호
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    • pp.65-84
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    • 2020
  • The potential use of Sargassum boveanum algae for the removal of uranium from aqueous solution has been studied by varying three independent parameters (pH, initial uranium ion concentration, S. boveanum dosage) using a central composite design (CCD) under response surface methodology (RSM). Batch mode experiments were performed in 20 experimental runs to determine the maximum metal adsorption capacity. In CCD design, the quantitative relationship between different levels of these parameters and heavy metal uptake (q) were used to work out the optimized levels of these parameters. The analysis of variance (ANOVA) of the proposed quadratic model revealed that this model was highly significant (R2 = 0.9940). The best set required 2.81 as initial pH(on the base of design of experiments method), 1.01 g/L S. boveanum and 418.92 mg/L uranium ion concentration within 180 min of contact time to show an optimum uranium uptake of 255 mg/g biomass. The biosorption process was also evaluated by Langmuir, Freundlich, Temkin and Dubinin-Radushkevich isotherm models represented that the experimental data fitted to the Langmuir isotherm model of a suitable degree and showed the maximum uptake capacity of 500 mg/g. FTIR and scanning electron microscopy were used to characterize the biosorbent and implied that the functional groups (carboxyl, sulfate, carbonyl and amine) were responsible for the biosorption of uranium from aqueous solution. In conclusion, the present study showed that S. boveanum could be a promising biosorbent for the removal of uranium pollutants from aqueous solutions.