• 대한약침학회지
• /
• 제18권2호
• /
• pp.19-25
• /
• 2015

Objectives: Capsaicin (CAP) is the chief pungent principle found in the hot red peppers and the chili peppers that have long been used as spices, food additives and drugs. This study investigated the anticancer potential of CAP through its ability to modify extracellular matrix components and proteases during mice lung carcinogenesis. Methods: Swiss albino mice were treated with benzo(a) pyrene (50 mg/kg body weight dissolved in olive oil) orally twice a week for four successive weeks to induce lung cancer at the end of $14^{th}$ week. CAP was administrated (10 mg/kg body weight dissolved in olive oil) intraperitoneally. Extracellular matrix components were assayed; Masson's trichome staining of lung tissues was performed. Western blot analyses of matrix metalloproteases 2 and 9 were also carried out. Results: In comparison with the control animals, animals in which benzo(a)pyrene had induced lung cancer showed significant increases in extracellular matrix components such as collagen (hydroxy proline), elastin, uronic acid and hexosamine and in glycosaminoglycans such as hyaluronate, chondroitin sulfate, keratan sulfate and dermatan sulfate. The above alterations in extracellular matrix components were effectively counteracted in benzo(a)pyrene along with CAP supplemented animals when compared to benzo(a) pyrene alone supplemented animals. The results of Masson's trichome staining for collagen and of, immunoblotting analyses of matrix metalloproteases 2 and 9 further supported the biochemical findings. Conclusion: The apparent potential of CAP in modulating extracellular matrix components and proteases suggests that CAP plays a chemomodulatory and anti-cancer role working against experimentally induced lung carcinogenesis.

• 대한지역사회영양학회지
• /
• 제22권1호
• /
• pp.53-62
• /
• 2017

Objectives: This study was conducted to identify factors that influence the consumption of temple food and to find systematic methods improving the popularization of temple food. Methods: A self-administered questionnaire was applied to 304 temple food restaurant visitors, including 232 local and 72 foreign individuals. The questionnaire was designed to investigate recognition, consumption, preference and popularization of temple food among restaurant visitors. Results: The study population consisted of 30.6% men, 69.4% women. 76.3% were Korean while 23.7% were foreigners. The responses on their impression on temple food contained the words, "vegetarian" (4.64), "plain and familiar" (4.19), and "good for dieting" (4.16). The most commont reason to favor temple food was its "mild taste" (63.0%) in the local group while foreigners preferred it because it is "good for health" (35.8%). The preferred kind of side dish of the local group was roasted dish (4.40), stir-fried dish (4.39), blanched vegetables (4.36), and food boiled with sauce (4.23); foreigner's high preference was for stir-fried (4.67), Jangachi (4.63), food boiled with sauce (4.56), and Buggak (4.55).. Most respondents thought that it is necessary to maintain the traditional form of temple food. While 43.5 percent of Koreans responded that "the five pungent vegetables" could be allowed, 62.8 percent of foreign respondents said it is permissible. Conclusions: A systematic approach to improve the temple food that reflects both foreign and local preference while maintaining its originality is necessary for its globalization. Furthermore, restaurants specialized in temple food should be expanded and promoted through effective marketing strategies that would make the cuisine easily accessible and spread throughout the world.

• 동의생리병리학회지
• /
• 제29권3호
• /
• pp.203-217
• /
• 2015

Scolpendra subspinipes (centipede) is pungent in flavor, activates the channels to stop pain, and, removes toxins and resolves masses. So it has been used as a folk remedy. We researched folk remedies which used centipede as a single medicine and results of its prior clinical and experimental study, and figured out that centipedes are effective on ulcerative disease, herpes zoster, clavus, insect bite, inflammatory disease, furunculus, pain disease by external therapy, and oral administration is effective on anti-cancer such as hepatoma and uterine cancer, cerebrovascular disease, inhibition of atherosclerosis, sedation of central nervous system, antipyretic action, and anti-inflammation, and centipede Herb-Acupuncture is effective on inflammatory disease and pain disease. Centipede preparation materials for external therapy were sesame oil, perilla oil, vinegar, salt, and, burnt alum. Fumigation of centipede treated paronychia, pertussis, and hemorrhoids. For the external therapy, the way of centipede powder mixing with other materials has been used. It is needed that we use dusted powder to make skin absorb its ingredients more easily, and we study intensely minor ingredients to make centipede components absorbed more effectively and do pharmacological action. Also, fumigation, a kind of another external therapy, is considered to be effective treatment of upper respiratory infection like pertussis, so it needs an in-depth study on centipede fumigation.

• 한국식품과학회지
• /
• 제23권3호
• /
• pp.296-300
• /
• 1991

품종과 재배 지역을 달리한 한국산 고추(Capsicum annuum L.)에서 매운 맛 성분, 붉은 색, 크기, 무게가 어떠한 가를 규명하였다. 품종에 따른 건고추의 길이는 $7.0{\sim}9.4\;cm$, 자실체의 무게는 $1.22{\sim}3.09g$, capsaicin 함량은 $11.5{\sim}45.0\;mg%$, dihydrocapsaicin 함량은 $8.5{\sim}35.1\;mg%$, 붉은 색은 $6,270{\sim}7,920$ conventional color unit으로 나타났다. 매운 맛 성분과 붉은 색은 7개 품종간에 유의적 차이를 보였으나 두 성분간에는 상관관계가 없는 것으로 나타났다. 고추 3개 품종의 매운 맛 성분과 붉은 색은 5개 지역간에 유의적 차이를 보였다. 태양건조와 열풍건조를 시킨 경우 매운 맛 성분의 함량에서는 차이가 없었으나 붉은 색에서는 차이를 나타내었다.

• 한국식품과학회지
• /
• 제32권2호
• /
• pp.271-276
• /
• 2000

전자선 조사기법을 이용하여 고추분말의 살균방법을 연구하면서 살균이 가능한 조사선량이 고춧가루의 품질에 관련된 이화학적 특성에 미치는 영향을 감마선 조사와 비교하였다. 전자선 및 감마선 조사된 시료의 pH와 가용성 고형분은 조사선량 간에 유의적인 차이는 나타나지 않았다. 시료의 충당과 환원당 함량은 살균선량에서 변화가 없었다. 고추분말의 수용성색소와 capsanthin 함량은 조사선량의 증가와 더불어 감소하는 경향이었다. 그러나 고추의 매운맛 성분인 capsaicin과 dihydrocapsaicin 함량은 방사선 조사에 비교적 안정하여 15 kGy까지도 거의 변화가 없었다. 이상의 결과에서 전자선은 감마선과 시료의 이화학적 특성에 미치는 영향이 유사하였다.

• Journal of Nutrition and Health
• /
• 제38권8호
• /
• pp.656-662
• /
• 2005

Ginger (Zingiber of oficinale Roscoe, Zingiberaceae) is one of the most frequently and heavily consumed dietary condiments throughout the world. Besides its extensive use as a spice, the rhizome of ginger has also been used in traditional oriental herbal medicine for the management of symptoms such as common cold, digestive disorders, rheumatism, neurologia, colic, and motion-sickness. The oleoresin from rhizomes of ginger contains [6] -gingerol (1- [4'-hydroxy-3'-methoxyphenyl]-5-hydroxy-3-decanone) and its homologs as pungent ingredients that have been found to possess many interesting pharmacological and physiological activities, such as anti-inflammatory, analgesic, antipyretic, antiheatotoxic, and cardiotonic effects. However, the effect of [6]-gingerol on cell proliferation in breast cancer cell are not currently well known. Therefore, in this study, we examined effect of [6]-gingerol on protein and mRNA expression associated with cell proliferation in MDA-MB-231 human breast. cancer cell lines. We cultured MDA-MB-231 cells in presence of 0, 2.5, 5 and $10{\mu}M$ of [6] -gingerol. [6]-Gingerol inhibited breast cancer cell growth in a dose-depenent manner as determined by MTT assay. ErbB2 and ErbB3 protein and mRNA expression were decreased dose-dependently in cells treated with [6]-gingerol (p<0.05). In addition, phosphorylated Akt levels and total hぉ levels were markedly decreased in cells treated with $2.5{\mu}M$ [6]-gingerol (p<0.05). In conclusion, we have shown that [6]-gingerol inhibits cell proliferation through ErbB2 and ErbB3, reduction in MDA-MB-231 human breast cancer cell lines.

• Nutrition Research and Practice
• /
• 제7권4호
• /
• pp.267-272
• /
• 2013

The anti-obesity effects of a hot water extract from wasabi (Wasabia japonica Matsum.) leaves (WLE), without its specific pungent constituents, such as allyl-isothiocyanate, were investigated in high fat-diet induced mice. C57J/BL mice were fed a high-fat diet (control group) or a high-fat diet supplemented with 5% WLE (WLE group). Physical parameters and blood profiles were determined. Gene expression associated with lipid metabolism in liver and white adipose tissue were analyzed. After 120 days of feeding, significantly lower body weight gain, liver weight and epididymal white adipose tissue weight was observed in the WLE group compared to the control group. In liver gene expression within the WLE group, PPAR${\alpha}$ was significantly enhanced and SREBP-1c was significantly suppressed. Subsequent downstream genes controlled by these regulators were significantly suppressed. In epididymal white adipose tissue of the WLE group, expression of leptin, PPAR${\gamma}$, and C/EBP${\alpha}$ were significantly suppressed and adiponectin was significantly enhanced. Acox, related to fatty acid oxidization in adipocytes, was also enhanced. Our results demonstrate that the WLE dietary supplement induces mild suppression of obesity in a high-fat diet induced mice, possibly due to suppression of lipid accumulation in liver and white adipose tissue.

• 한국식생활문화학회지
• /
• 제25권5호
• /
• pp.598-606
• /
• 2010

Kimchi is the most well-known Korean traditional food, but it is also the main leftover of school lunch and dinner menus. This study aimed to familiarize teenagers with kimchi through school meals and to increase their daily kimchi intake, ultimately by appealing to the young generation's taste. A questionnaire survey was conducted in the Ansan area to examine student's acceptability of kimchi and their attitudes toward kimchi. Approximately 65% of males and 67% of female students liked the moderately fermented and pungent taste of kimchi. Kimchi served in school meals was regarded as nutritional but cheap. Approximately 72% of male and 82% of female students responded that they liked menu items using kimchi. Approximately 48% of students responded that menu items using kimchi in schools are not diverse. Students preferred meat as an ingredient in kimchi. The preferred cooking methods were stir-frying and frying, whereas boiling was the least favorite. Based on the survey results, ten kimchi menu items had been developed. The suitability of the menu was evaluated by students and cooks. Six kimchi items, including Kimchi mixed with rice, chicken, soybean sprouts, Kimchi cheese rice, stewed beef ribs with kimchi, rice topped with kimchi curry, kimchi cheese meat roast, and kimchi udong were considered appropriate for school meals, whereas kimchi kangchong, kimchi topokki, kimchi stew with surimi, and frozen Pollack kimchi soup were not suitable as menu items. Kimchi topokki was not accepted by students, while kimchi kangchong was not accepted by cooks. Cooks judged the suitability of a menu item by the cooking process and cooking times, whereas students judged an item by its sensory preference. Approximately 63% of students responded that kimchi intake has increased by participating in the development of kimchi dishes.

• 생태와환경
• /
• 제56권4호
• /
• pp.303-319
• /
• 2023

Pitfall traps that use ethylene glycol as a preservative solution are commonly used in arthropod research. However, a recent surge in cases involving damage to these traps by roe deer or wild boars owing to the sweet taste of ethylene glycol has prompted the addition of quinone sulfate, a substance with a pungent taste, to deter such wildlife interference. This study aimed to assess the effects of quinone sulfate on arthropods collected from pitfall traps containing ethylene glycol. We strategically positioned 50 traps using ethylene glycol alone and 50 traps containing a small amount of quinone sulfate mixed with ethylene glycol in a grid pattern for systematic sampling at the Gwangneung Forest long-term ecological research (LTER) site. Traps were collected 10 days later. The results revealed a notable effect on ants when quinone sulfate was introduced. Specifically, it decreased the number of ants. In a species-specific analysis of ants, only Nylanderia flavipes showed a significant decline in response to quinone sulfate, whereas other ant species remained unaffected. Additionally, among the arthropod samples obtained in this survey, we identified species or morpho-species of spiders, beetles, and ants and assessed species diversity. Consequently, the utilization of quinone sulfate should be undertaken judiciously, taking into account the specific species composition and environmental characteristics of the monitoring site. Our study also highlighted the significant response of various arthropod groups to variations in leaf litter depth, underscoring the crucial role of the leaf litter layer in providing sustenance and shelter for ground-foraging arthropods. Furthermore, we have compiled comprehensive species lists of both spiders and ants in Gwangneung forest by amalgamating data from this investigation with findings from previous studies.

• 한국식품영양과학회지
• /
• 제38권1호
• /
• pp.105-110
• /
• 2009

마늘을 여러 가지 방법으로 열처리해 새로운 무취마늘 식품소재를 개발하기 위해 마늘을 삶기($100^{\circ}C$, 60 min), 찌기 ($100^{\circ}C$, 30 min), 굽기($120^{\circ}C$, 10 min), 고온고압처리($120^{\circ}C$, 20 min, 1.5 kgf/$cm^2$)하여 이화학적, 관능적 특성 및 항산화성을 평가하였다. 마늘의 색도 측정 결과 생마늘에 비해 가열처리된 마늘이 L값이 감소하였으며, a값과 b값은 유의적으로 증가하였다(p<0.05). 가열처리된 마늘의 기계적 경도, 씹힘성, 검성은 유의적으로 감소하였으며(p<0.05), 고온고압 처리한 경우에 크게 감소하였다. DPPH 라디칼 소거능 및 hydroxyl 라디칼 소거능에 대한 항산화 활성은 생마늘(대조구)에 비해 가열처리된 마늘에서 다소 감소하는 경향을 보였다. 그러나 가열방법에 따라서는 고온고압처리 마늘이 항산화 활성이 가장 우수하였다. 관능적 특성 중 강도평가에서 매운맛, 마늘 냄새에 대해서는 생마늘에 비해 가열처리된 마늘이 유의적으로 강도가 낮게 평가되었고(p<0.05), 특히 고온고압처리 마늘이 매운맛(1.6점), 자극적 냄새(1.5점)가 가장 적었다. 이상의 결과를 토대로 마늘 무취화를 위한 가열처리 방법으로는 고온고압처리가 가장 적합하다고 판단하였다. 그리고 가열처리로 인한 항산화성 감소를 보완하고자, 마늘을 고온고압처리 시 허브(녹차, 월계수, 계피, 솔잎)를 10% 첨가하여 DPPH radical 소거능으로 항산화성을 평가한 결과 녹차를 첨가했을 때 가장 우수한 항산화성을 보였다. 또한 경제적인 면을 고려하여 녹차의 첨가량을 1%로 줄이고 5% 숯을 첨가하여 DPPH radical 소거능을 측정했을 때 10% 첨가구에 비해 $IC_{50}$값이 감소하여 적은 양의 녹차로도 항산화작용이 나타나는 것을 알 수 있었다. 결과적으로 마늘의 무취화에 고온고압처리를 적용할 수 있으며, 녹차를 함께 첨가할 경우 항산화성 보완할 수 있음을 확인하였다.