• 한방안이비인후피부과학회지
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• 제19권1호
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• pp.135-144
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• 2006

Objective : The purpose of this study was to know the clinical effects of hydrotherapy based Ultrasonic spa using SoPung-Tang on pulse wave velocity in patients with sequelae of CVA. Methods : PWV(Pulse wave velocity), Bio Chemistry, Hematology, Blood Pressure were investigated in 20 patients(Experimental group 13, Control group 7) who have been in Semyung Oriental medicine hospital from December 2005 to February 2006. Results : 1. In experimental group, Rt PWV diminished 4.8%, Lt PWV 5.1%. 2. In control group, Rt PWV diminished 3.3%, Lt PWV 1.8%. Conclusion : Hydrotherapy based Ultrasonic spa using SoPung-Tang showed useful effects in patients with sequelae of CVA.

• Journal of Acupuncture Research
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• 제28권2호
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• pp.97-105
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• 2011

Objectives : The aim of this experiment is to know the effect of mountain cultivated ginseng pharmacopuncture on heart rate variability(HRV), pulse wave velocity(PWV) in middle aged women. Methods : We investigated on 20 healthy Middle Aged women volunteers. First, we measured their heart rate variability(HRV), pulse wave velocity(PWV) and then mountain cultivated ginseng pharmacopuncture 20cc were injected on them. After 30 minutes, we measured heart rate variability(HRV), pulse wave velocity(PWV) again. As a result, method of one-group pretest-posttes design were used for evaluation. Results : 1. In HRV, MeanHRV is significantly decreased from 69.15 to 63.34 after injection. 2. MeanRR is significantly increased from 877.20 to 962.10 after injection. SDNN is significantly increased from 32.56 to 41.34 after injection. 3. PNN50 is significantly decreased after injection. RNSSD, SDSD, TP, VLF is significantly increased after injection. 4. Stress resistance ability is significantly increased from 37.55 to 44.60 after injection. 5. In PWV, E-R, E-L, H-R, H-L is significantly decreased after injection. Conclusions : Effect of mountain cultivated ginseng pharmacopuncture on heart rate variability(HRV) increased adaptability of autonomic nervous system and on pulse wave velocity(PWV) decreased arterial stiffness.

• 대한임상검사과학회지
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• 제47권1호
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• pp.28-34
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• 2015

Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring arterial stiffness. Increased arterial stiffness measured by PWV stands for progressive arteriosclerosis and is caused by atherosclerotic risk factors. This study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to the leading risk factors for arteriosclerosis or atherosclerosis. Subjects were 114, 69 males and 45 females who are in 60's and had baPWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbA1c, total cholesterol, BSBP (brachial artery systolic blood pressure), BDBP (brachial artery diastolic blood pressure), CSBP (central artery systolic blood pressure), CDBP (central artery diastolic blood pressure), augmentation index (AIx) and diabetes mellitus. Correlation analysis between baPWV and atherosclerotic risk factor showed significant relationship in age, HbA1c, LDL cholesterol, BSBP, BDBP, CSBP, CDBP and augmentation index. baPWV was independently related to age and BSBP in multiple linear regression analysis. The group with increased arterial stiffness was independently related to BDBP in multiple logistic regression analysis. This study might be meaningful in evaluating the relationship between arterial stiffness and atherosclerotic risk factor in a new way, and be helped to make various studies for cardiovascular disease.

• 동의생리병리학회지
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• 제26권5호
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• pp.745-752
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• 2012

This study aims to show the change of Heart Rate Variability(HRV) and Pulse wave velocity(PWV) on menstruation in women at college. Heart Rate Variability(HRV) and Pulse wave velocity(PWV) of 122 women at college were measured at their menstruation and ordinary period. SDNN, RMSSD, SDSD, HRV Index(%), stress resistance and cardiac activity were significantly higher at their menstruation than ordinary period, but Total Power and pNN50(%) were opposite. The automatic nervous system balance and physical stress were decreased in groups without dysmenorrhea than with one. PWV(E-R) and PWV(E-L) were much higher at menstruation than ordinary period. PTT(F-R) and PTT(F-L) were decreased in groups without dysmenorrhea than with severe one. We demonstrated that menstruation can effect on Heart Rate Variability and Pulse wave velocity and dysmenorrhea can cause the imbalance of autonomic nervous system.

• 대한한의진단학회지
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• 제15권3호
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• pp.245-260
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• 2011

Objectives: The aim of this experiment is to know the effect of Mountain Cultivated Ginseng Pharmacopuncture on Heart Rate Variability (HRV), Pulse wave velocity (PWV) in Middle Aged Women. Methods: We investigated on 40 women of breast cancer patients. First, we measured their Heart Rate Variability(HRV), Pulse wave velocity (PWV) and then Mountain Cultivated Ginseng Pharmacopuncture $20m{\ell}$ were injected on them. After 30 minutes, we measured Heart Rate Variability(HRV), Pulse wave velocity(PWV) again. As a result, method of non-equivalent control group non-synchronized design were used for evaluation. Results: In HRV, Mean HRV is significantly decreased from 69.15 to 63.34 after injection. Mean RR is significantly increased from 877.20 to 962.10 after injection. SDNN is significantly increased from 32.56 to 41.34 after injection. PNN50 is significantly decreased after injection. RNSSD, SDSD, TP, VLF is significantly increased after injection. Stress Resistance ability is significantly increased from 37.55 to 44.60 after injection. And In PWV, E-R, E-L, H-R, H-L is significantly decreased after injection. Conclusions: Effect of Mountain Cultivated Ginseng Pharmacopuncture on Heart Rate Variability (HRV) increased adaptability of autonomic nervous system and on Pulse wave velocity (PWV) decreased arterial stiffness.

• 한국자기학회지
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• 제23권4호
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• pp.130-134
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• 2013

자성센싱 홀소자가 구비된 집게형 맥진기와 대중적인 생체신호를 측정하는 심전도를 이용하여 맥파전달속도(PWV)를 조사하였다. 동시 측정된 심전도파의 피크치와 요골동맥파의 시작점의 시간차 그리고 심장과 손목간의 거리차를 가지고 맥파전달속도를 계산하였다. 임상데이터로부터 분석된 PWV값은 5~7 m/s의 범위 안에 평균 6 m/s이었다. 맥파전달속도 분석을 통한 혈관탄성도를 예측함으로써, 미래의 한양방 협진용 건강관리 의료기기에서 제시하는 주요 지수로 응용할 수 있는 가능성을 확인하였다.

• 센서학회지
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• 제20권5호
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• pp.343-350
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• 2011

The compliance and stiffness of artery are closely related with disease of arteries. Pulse wave velocity(PWV) in the blood vessel is a basic and common parameter in the hemodynamics of blood pressure and blood flow wave traveling in arteries because the PWV is affected directly by the conditions of blood vessels. However, there is no standardized method to measure the PWV and it is difficult to measure. The conventional PWV measurement has being done by manual calculation of the pulse wave transmission time between coronary arterial proximal and distal points on a strip chart on which the pulse wave and ECG signal are recorded. In this study, a pressure sensor consisting of strain gauges is used to measure the blood pressure of arteries in invasive method and regular ECG electrodes are used to record the ECG signal. The R-peak point of ECG is extracted by using a reference level and time windowing technique and the ascending starting point of blood pressure is determined by using differentiation of the blood pressure signal and time windowing technique. The algorithm proposed in this study, which can measure PWV automatically, shows robust and good results in the extraction of feature points and calculation of PWV.

• 대한한방내과학회지
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• 제30권3호
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• pp.525-533
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• 2009

Objectives : There are lots of reports that cardiovascular disease, including hypertension, cerebro-vascular accident, and coronary heart disease, is related to atherosclerotic changes. Increased serum levels of lipids could play a role in these changes. This study aimed to investigate the relationship between PWV and risk factors of cardiovascular disease, including serum lipid values. Methods : This study included 261 subjects ($49.32{\pm}11.79$ years, 112 male) who underwent PWV and serum lipid evaluation. We investigated the correlation between serum lipid values, blood pressure, body mass index (EMI) and PWV. Pearson's correlation and partial correlation analysis were applied to examine the relationship between PWV and risk factors of cardiovascular disease. Results : Serum triglyceride, total cholesterol, systolic blood pressure, and diastolic blood pressure were significantly correlated with PWV. Partial correlation coefficient adjusted by age yielded significant correlation between serum triglyceride, systolic blood pressure, diastolic blood pressure and PWV. Conclusion : In this study, it seems that there are significant relationships between PWV, triglyceride and blood pressure. We could suggest that PWV might have some relationships with Dam-eum and blood stasis in oriental theory.

• Transactions on Electrical and Electronic Materials
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• 제9권5호
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• pp.213-219
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• 2008

Pulse waves continuously change with respect to the characteristics and status of the cardiovascular system and in relation to the blood pressure (BP) and the pulse wave velocity (PWV). Monitoring the vascular condition by analyzing the variations in pulse waveforms has been used to diagnose vascular disorders and in drug treatment of arteriosclerosis and peripheral circulatory obstruction. In this paper, we investigated the vascular characteristic index with regard to the BP and classified by pulse wave signals. The pressure pulse wave and photoplethysmography (PPG) were measured simultaneously while subjects exercised, producing changes in the BP, to analyze the variation in the vascular characteristic index. We investigated the correlation between the BP and vascular characteristic index with regard to the classification methods of the pulse wave. The reflection index (RI) and vascular stiffness index were correlated with the diastolic BP, but no correlation was found between these parameters and the systolic BP. These results suggest the possibility of estimating BP through simple measurements of pulse waves.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.777-785
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• 2007

In this paper, Finger-Toe Index (FTI) is proposed as an analytic parameter for the characterization of arterial vessel. Different from the currently being employed pulse wave velocity (PWV) information of the volume pulse wave measured from 4 arterial channels, the proposed FTI uses the ratio of the shorter of the two up-stroke time of PPG from fingers ($UT_{finger}$) and that of PPG (Photoplethysmography) from toes ($UT_{toe}$). To verify the usefulness of the proposed method, Finger-Toe Indexes were derived from the volume pulse waves acquired from 50 people under examination aged from 12 to 81 years old, and they were then compared with blood pressure ankle-brachial index (ABI). It was successfully demonstrated that the arterial stiffness can be estimated with respect to age and FTI is more strongly correlated with the pulse transit time than ABI. From the regression analysis, we also found that FTI has significant correlation PWV for a quantitative index of arterial stiffness and provides more accurate information than ABI for the characterization of arterial vessel.