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Doherty Amplifier Using Load Modulation and Phase Compensation DGS Micro-Strip Line (부하 변조 및 위상 보상 DGS 마이크로스트립 선로를 이용한 도허티 증폭기)

  • Choi Heung-Jae;Lim Jong-Sik;Jeong Yong-Chae
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.16 no.8 s.99
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    • pp.815-824
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    • 2005
  • In this paper, we proposed a new DGS(Defected Ground Structure) Doherty amplifier for IMT-2000 band. Originally, active load-pull analysis of a Doherty amplifier assumes ideal harmonic termination condition. However, there have been no papers considering this ideal harmonic termination condition. We obtained excellent improvements of efficiency, gain, maximum output power as well as superior size reduction of a Doherly amplifier by satisfying the overlooked assumption of ideal harmonic termination through the adaptation of DGS at the output transmission line of carrier and peaking amplifier that is essential for Doherty operation. The amount of both the 2nd and the 3rd harmonic rejection of the proposed DGS Doherty amplifier over the conventional one are 44.92 dB and over 23.77 dB, respectively. The acquired improvement in Pl dB, gain, drain efficiency, and ACPR to WCDMA 1FA signal were 0.42 dB, 0.33 dB, $6.4\%$ and 5.4 dBc, respectively. Moreover, electrical length of $90{\circ}$ is reduced at each of the DGS carrier amplifier path and DGS peaking amplifier path, therefore the whole amplifier circuit size is considerably reduced.

AtMAP65-1 Binds to Tubulin Dimers to Promote Tubulin Assembly

  • Li, Hua;Yuan, Ming;Mao, Tonglin
    • BMB Reports
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    • v.40 no.2
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    • pp.218-225
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    • 2007
  • In Arabidopsis thaliana, the microtubule-associated protein AtMAP65-1 shows various functions on microtubule dynamics and organizations. However, it is still an open question about whether AtMAP65-1 binds to tubulin dimers and how it regulates microtubule dynamics. In present study, the tubulin-binding activity of AtMAP65-1 was investigated. Pull-down and co-sedimentation exp eriments demonstrated that AtMAP65-1 bound to tubulin dimers,at a molar ratio of 1 : 1. Cross-linking experiments showed that AtMAP65-1 bound to tubulin dimers by interacting with $\alpha$-tubulin of the tubulin heterodimer. Interfering the bundling effect of AtMAP65-1 by addition of salt and monitoring the tubulin assembly, the experiment results indicated that AtMAP65-1 promoted tubulin assembly by interacting with tubulin dimers. In addition, five truncated versions of AtMAP65-1, namely AtMAP65-1 $\Delta$N339 (amino acids 340-587); AtMAP65-1 $\Delta$N494 (amino acids 495-587); AtMAP65-1 340-494 (amino acids 340-494); AtMAP65-1 $\Delta$C495 (amino acids 1-494) and AtMAP65-1 $\Delta$C340 (amino acids 1-339), were tested for their binding activities and roles in tubulin polymerization in vitro. Four (AtMAP65-1 $\Delta$N339, $\Delta$N494, AtMAP65-1 340-494 and $\Delta$C495) from the five truncated proteins were able to co-sediment with microtubules, and three (AtMAP65-1 $\Delta$N339, $\Delta$N494 and AtMAP65-1 340-494) of them could bind to tubulin dimers in vitro. Among the three truncated proteins, AtMAP65-1 $\Delta$N339 showed the greatest activity to promote tubulin polymerization, AtMAP65-1 $\Delta$N494 exhibited almost the same activity as the full length protein in promoting tubulin assembly, and AtMAP65-1 340-494 had minor activity to promote tubulin assembly. On the contrast, AtMAP65-1 $\Delta$C495, which bound to microtubules but not to tubulin dimers, did not affect tubulin assembly. Our study suggested that AtMAP65-1 might promote tubulin assembly by binding to tubulin dimers in vivo.

Stratigraphy of the Kachi-1 Well, Kunsan Basin, Offshore Western Korea (한국 서해 대륙붕 군산분지 까치-1공의 층서)

  • Ryu, In-Chang;Kim, Tae-Hoon
    • Economic and Environmental Geology
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    • v.40 no.4
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    • pp.473-490
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    • 2007
  • Strata of the Kachi-1 well, Kunsan Basin, offshore western Korea, were analyzed by using integrated stratigraphy approach. As a result, five distinct unconformity-bounded units are recognized in the well: Triassic, Late Jurassic-Early Cretaceous, Early Cretaceous, Late Cretaceous, and Middle Miocene units. Each unit represents a tectono-stratigraphic unit that provides time-sliced information on basin-forming tectonics, sedimentation, and basin-modifying tectonics of the Kunsan Basin. In the late Late Jurassic, development of second- or third-order wrench faults along the Tan-Lu fault system probably initiated a series of small-scale strike-slip extensional basins. Continued sinistral movement of these wrench faults until the Late Cretaceous caused a mega-shear in the basin, forming a large-scale pull-apart basin. However, in the Early Tertiary, the Indian Plate began to collide with the Eurasian Plate, forming a mega-suture zone. This orogenic event, namely the Himalayan Orogeny, continued by late Eocene and was probably responsible for initiation of right-lateral motion of the Tan-Lu fault system. The right-lateral strike-slip movement of the Tan-Lu fault caused the tectonic inversion of the Kunsan Basin. Thus, the late Eocene to Oligocene was the main period of severe tectonic modification of the basin. After the Oligocene, the Kunsan Basin has maintained thermal subsidence up to the present with short periods of marine transgressions extending into the land part of the present basin.

Surgical Treatment of the Fracture of the Scapular Body (견갑골 체부 골절의 수술적 치료)

  • Rhyou, In-Hyeok;Suh, Bo-Gun;Chung, Chae-Ik;Kim, Kyung-Chul
    • Clinics in Shoulder and Elbow
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    • v.11 no.2
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    • pp.150-157
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    • 2008
  • Purpose: We wanted to evaluate the results of surgical treatment for fracture of the scapular body. Materials and methods: The subjects of this study were seven patients with fracture of the scapular body and all these patients were managed surgically. We considered the operative indications as being 100% translation of the lateral border, or $25^{\circ}$ of angular deformity of the glenoid, or 1cm medialization or the variant of the double disruption of the superior scapular suspensory complex. There were five males and two females, and their ages ranged between 40 and 58 years (mean age: 49) with average follow up of 11 months (6~24 months). Two patients sustained multiple fractures of the ribs and spines. The surgical results were evaluated according to the subjective satisfaction, the UCLA score and the Korean shoulder score. Results: The mean UCLA score was 29 (17~33) and the mean Korean shoulder score was 86 (63~94). The self assessment for subjective satisfaction was 7.7 (4~9). There were two complications; one case of screw pull-out without the loss of the fracture fixation and the other case with screw penetration of the glenoid cavity. Conclusion: Surgical treatment may be effective for the management of severely displaced fracture of the scapular body in order to prevent the impairment of the shoulder function caused by the altered glenohumeral and scapulothoracic kinematics.

Loop Suture Technique for Flexor Digitorum Profundus Tendon Repair in the Insertion Site (고리 봉합법을 이용한 심부 수지 굴건 종지부에서의 건봉합)

  • Lee, Kyu-Cheol;Lee, Dong-Chul;Kim, Jin-Soo;Ki, Sae-Hwi;Roh, Si-Young;Yang, Jae-Won
    • Archives of Plastic Surgery
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    • v.37 no.5
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    • pp.650-658
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    • 2010
  • Purpose: In the case of repair for far distal parts of FDP (Flexor digitorum profundus) division, the method of either pull-out suture or fixation of tendon to the distal phalanx is preferred. In this paper, the results of a modified loop suture technique used for the complete division of FDP from both zone 1a and distal parts of zone 1b in Moiemen classification are presented. Methods: From July 2006 to July 2009, the modified loop suture technique was used for the 10 cases of FDP in complete division from zone 1a and distal parts of zone 1b, especially where insertion sites were less than 1 cm apart from a tendon of a stump. In a suture technique, a loop is applied to each distal and proximal parts of tendon respectively. Core suture of 2-strand and epitendinous suture are done with PDS 4-0. Out of 10 patients, the study was done on 6 patients who were available for the followup. The average age of the patients was 49.1 years (in the range from 26 to 67). 5 males and 1 female patients were involved in this study. There were 3 cases with zone 1a and distal parts of zone 1b. The average distance to the distal tendon end was 0.6 cm. There were 5 cases underwent microsurgical repair where both artery and nerve divided. One case of only tendon displacement was presented. The dorsal protective splint was kept for 5 weeks on average. The results of the following tests were measured: active & passive range of motion, grip strength test, key pinch and pulp pinch test. Results: The follow-up period on average was 11 months, in the range from 2 to 20 months. There was no case of re-rupture, but tenolysis was performed in 1 cases. In all 6 cases, the average active range of motion of distal interphalangeal joint was 50.8 degree. The grip strength (ipsilateral/contralateral) was measured as 88.7% and the pulp pinch test was 79.2% as those of contralateral side. Flexion contracture was presented in 2 cases (15 degree on average) and there was no quadrigia effect found. Conclusion: Despite short length of tendon from the insertion site in FDS rupture in zone 1a and distal parts of zone 1b, sufficient functional recovery could be expected with the tendon to tendon repair using the modified loop suture technique.

Angiostrongylus cantonensis: Scanning Electron Microscopic Observations on The Cuticle of Moulting Larvae

  • Zeng, Xin;Wei, Jie;Wang, Juan;Wu, Feng;Fung, Feng;Wu, Xiaoying;Sun, Xi;Zheng, Huanqing;Lv, Zhiyue;Wu, Zhongdao
    • Parasites, Hosts and Diseases
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    • v.51 no.6
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    • pp.633-636
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    • 2013
  • Angiostrongylus cantonensis is a parasitic nematode that needs to develop in different hosts in different larval stages. Freshwater snails, such as Pomacea canaliculata, are the intermediate host, and rats are the definitive host. Periodic shedding of the cuticle (moulting) is an important biological process for the survival and development of the parasite in the intermediate and definitive hosts. However, there are few studies on the cuticle alterations between different stages of this parasite. In this study, we observed the ultrastructural appearance and changes of the cuticle of the 2nd/3rd stage larvae (L2/L3) and the 3rd/4th stage larvae (L3/L4) using a scanning electron microscope. We also first divided L2/L3 into late L2 and early L3. The late L2 lacked alae, but possessed a pull-chain-like fissure. Irregular alignment of spherical particles on the cuticle were noted compared to the L3. Alae appeared in the early L3. The old cuticle turned into a thin filmlike structure which adhered to the new cuticle, and spherical particles were seen regularly arranged on the surface of this structure. Regular rectangular cavities were found on the surface of L3/L4. The caudal structure of L3/L4 was much larger than that of L3, but caudal inflation, such as seen in L4, was not observed. These results are the first to reveal the ultrastructural changes of the cuticle of A. cantonensis before and after moulting of L2/L3 and L3/L4.

Functional Screening for Cell Death Suppressors and Development of Multiple Stress-Tolerant Plants

  • Moon, Hae-Jeong;Baek, Dong-Won;Lee, Ji-Young;Nam, Jae-Sung;Yun, Dae-Jin
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2003.04a
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    • pp.65-71
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    • 2003
  • Bax, a mammalian pro-apoptotic member of the Bcl-2 family, induces cell death when expressed in yeast. To investigate whether Bax expression can induce cell death in plant, we produced transgenic Arabidopsis plants that contained murine Bax cDNA under control of a glucocorticoid-inducible promoter. Transgenic plants treated with dexamethasone, a strong synthetic glucocorticoid, induced Bax accumulation and cell death, suggesting that some elements of cell death mechanism by Bax may be conserved among various organisms. Therefore, we developed novel yeast genetic system, and cloned several Plant Bax Inhibitors (PBIs). Here, we report the function of two PBIs in detail. PBI1 is ascorbate peroxidase (sAPX). Fluorescence method of dihydrorho-damine 123 oxidation revealed that expression of Bax in yeast cells generated reactive oxygen species (ROS), and which was greatly reduced by co-expression with sAPX. These results suggest that sAPX inhibits the generation of ROS by Bax, which in turn suppresses Baxinduced cell death in yeast. PBI2 encodes nucleoside diphosphate kinase (NDPK). ROS stress strongly induces the expression of the NDPK2 gene in Arabidopsis thaliana (AtNDPK2). Transgenic plants overexpressing AtNDPK2 have lower levels of ROS than wildtype plants. Mutants lacking AtNDPK2 had higher levels of ROS than wildtype. $H_2O_2$ treatment induced the phosphorylation of two endogenous proteins whose molecular weights suggested they are AtMPK3 and AtMPK6. In the absence of $H_2O_2$ treatment, phosphorylation of these proteins was slightly elevated in plants overexpressing AtNDPK2 but markedly decreased in the AtNDPK2 deletion mutant. Yeast two-hybrid and in vitro protein pull-down assays revealed that AtNDPK2 specifically interacts with AtMPK3 and AtMPK6. Furthermore, AtNDPK2 also enhances the MBP phosphorylation activity of AtMPK3 in vitro. Finally, constitutive overexpression of AtNDPK2 in Arabidopsis plants conferred an enhanced tolerance to multiple environmental stresses that elicit ROS accumulation in situ. Thus, AtNDPK2 appears to play a novel regulatory role in $H_2O_2$-mediated MAPK signaling in plants.

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Complications of Femoral Lengthening Using Monolateral External Fixator in Rabbits (토끼에서 단측성 외고정기구를 이용한 대퇴골 신연술의 합병증)

  • Song, Hae-Ryong;Hwang, Jae-Min;Koo, Ja-Min;Kim, Hyeon-Hui;Lee, Won-Ik;Kim, Gon-Sup;Lee, Hyo-Jong;Chang, Ki-Churl;Yeon, Seong-Chan
    • Korean Journal of Veterinary Research
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    • v.42 no.3
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    • pp.411-418
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    • 2002
  • Thirty rabbits underwent femoral lengthening using monolateral external fixator to evaluate results and complications of limb lengthening. Twenty rabbits survived until consolidation of callus formed at the lengthening site after finishing lengthening. Ten rabbits were sacrificed during femoral lengthening because of complications. Survived 20 rabbits were classified to two groups according the amount of lengthening: group I (10% lengthening of the femoral length); group II (20% lengthening). There was no significant difference of consolidation time between two groups (p=0.25). Varus angulation at the lengthening site occurred in 60% of two groups and the amount of varus angulation in group II was larger than that of group I. Degenerative change of articular cartilage at the medial condyle of the distal femur was found in 30% of group II. Of sacrificed ten rabbits, 5 had pin loosenings with pull an of pins from the femur, 2 had fermoral fractures around the pin-tract site, and 3 had severe osteomyelitis of the femur around the pin-tract site.

The Cenetic Implication of Hydrothermal Alteration of Epithermal Deposits from the Mugeuk Area (무극 지역 천열수 광상 열수변질대의 성인적 의미)

  • 박상준;최선규;이동은
    • Journal of the Mineralogical Society of Korea
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    • v.16 no.3
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    • pp.265-280
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    • 2003
  • The Mugeuk mineralized area that associated with the pull-apart type Cretaceous Eumseong basin is composed of several gold-silver vein deposits that are emplaced in late Cretaceous biotite granite. The gold-silver deposits in the area show various hydrothermal alteration zones as well as Au/Ag ratios and ore mineralogy. The Geumbong mine showing relatively high gold fineness is composed of multiple veins and show alteration pattern; vein \longrightarrow phyllic \longrightarrow subphyllic \longrightarrow propylitic \longrightarrow subpropylitic zone. In contrast, The Taegeuk mines show the low fineness values, in far southern part are characterized by increasing tendency of simple and/or stockwork veins. The deposit displays alteration pattern; vein \longrightarrow propylitic \longrightarrow subpropylitic zone. Variations of alteration zone with depth show that phyllic zone are dominant in deeper level and propylitic zone sporadically overlapped by argillic zone are dominant in shallow level. The differences of alteration pattern between the gold-silver deposits are reflect the evolution of the hydrothermal fluids; the ore-forming fluids of the Geumbong mine are at relatively high temperature and salinity and highly-evolved meteoric water, developing phyllic zone, the Taegeuk mine containing greater amounts of less-evolved meteoric waters shows relatively low temperature and salinity in ore-forming fluids, developing propylitic zone. The various physicochemical environment for gold-silver mineralization in the Mugeuk mineralized area is due to proximity from heat source area (Mugeuk mine) to marginal area (Taegeuk mine) in a geothermal field. Therefore, it is suggested that the criteria for project exploration in the area are to focus on the area proximal to heat source and phyllic zone.

The Development Scheme of Domestic Third Party Logistics for Revitalization of Electronic Trade (전자무역의 활성화를 위한 국내 제3자물류 발전방안)

  • Cha, Soon-Kwean;Jang, Heung-Hoon
    • Journal of Korea Port Economic Association
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    • v.24 no.2
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    • pp.155-174
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    • 2008
  • This paper proposed several activation strategies at both the government and company parts for the development of domestic third party logistics(TPL) to pull electronic trade era much earlier. In the government side, it must need to arrange and integrate complex regulation rules on the Logistics for more smooth access and use the TPL market. Also, it has to provide multiple support policies such as tax reduction, technical and financial service providing, and logistics information system to TPL. Finally, it should construct the government levels education system to train and forster a competent man who is well qualified as a electronic and logiscic expert. The TPL company must build up a total logistics information system concerned with an innovative operation system such as SCM, JIT etc. which can provide logistic services on demand to the electronic trade customers to maximize consumer satisfaction. In the shipper company level, it try to join a long-term strategic alliance with TPL to reduce logistic cost and increase logistic service to its electronic trade consumers.

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