• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.5
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• pp.530-539
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• 2013

This study reviews the latest articles about oriental and traditional medicine treatment of male sexual dysfunction. We searched the article from 2000 to 2012 using 5 data bases. There were no restrictions on the type of publication, but articles not available in full text were excluded. The methological quality of RCT study was assessed according to Jadad scores and Cochrane's assessment of risk of bias. 18 articles were included in this study. 5 articles published in Korea, the rest were foreign articles. 9 articles were randomized controlled trial(RCT), Case-control studies were 3, case reports were 3, One group pre-post test were 3. In RCT studies, Jadad scores were generally low, and risk of selection bias and performance bias were generally high, risk of detection bias was unclear. Oriental and traditional medicine treatment is as effective as western medicine treatment for male sexual dysfunction, more rigorous oriental medicine treatment studies should be warranted.

• Journal of the Korean Society for information Management
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• v.32 no.4
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• pp.205-221
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• 2015

The impact of a journal is commonly used as the impact of an individual paper within that journal. It is problematic to interpret a journal's impact as a single paper's impact of the journal, so there are several researches to measure a single paper's impact with its own citation counts. This study applied 8 impact indicators to Korean Citation Index database and examined discipline bias of each indicator. Analyzed indicators are simple citation counts, PageRank, f-value, CCI, c-index, single publication h-index, single publication hs-index, and cl-index. PageRank has the least discipline bias at highly ranked papers and journal bias in a discipline. On the contrary, simple citation counts showed strongly biased results toward a certain discipline or a journal. KCI database provides only simple citation counts. It needs to show PageRank (global indicator) to discover influential papers in diverse areas. Furthermore it needs to consider to provide the best of local indicators. Local indicators can be calculated only with papers in users' search results because they uses citation counts of citing papers and the number of references. They are more efficient than global indicators which explore the whole database. KCI should also consider to provide Cl-index (local indicator).

• Journal of Digital Convergence
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• v.16 no.11
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• pp.419-432
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• 2018

The purpose of this study is to develop a hospice intervention program and present basic study data using a method of Meta analysis. Fifteen theses from 2002 to 2017 were collected from the on-line database at Korean Education and Research Information Service and other journals related hospice. Main keywords were 'hospice' and intervention'. The selected 15 theses were analyzed with publication bias, outcome of effect size, non-overlap percentage(U3), 95% confidence intervals and homogeneity. The result of the study is summarized as follows; Publication bias was stable and the effect size of hospice program was significant at. 99. The effective and significant regulation effects were publication years with 2003 to 2007(ES=1.24), publication types with journals(ES=1.33), majors with nursing sciences(ES=1.02), ages with 29 to 30(ES=1.09), later session(ES=1.06) and aroma(ES=1.12). Accordingly, this thesis has its meaning in that it used a Meta-analysis to analyze domestic theses of hospice intervention programs for the first time in Korea. This thesis will prodide specific guidance to researchers trying to develop and utilize hospice intervention programs resulting in helpful usages in professional hospice institutions with implementations of programs.

• Journal of Korean Academy of Nursing
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• v.43 no.5
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• pp.658-668
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• 2013

Purpose: The purpose of this study was to investigate the effects of psychosocial interventions on pain in cancer patients. Methods: Eight studies published between 1980 and 2012 in Korean and ten studies published between 2002 and 2012 in English met the inclusion criteria with a total of 1539 participants. Methodological quality assessed by Cochrane's Risk of Bias for randomized studies and Risk of Bias Assessment tool for non randomized studies. The data were analyzed by the RevMan 5.2 program of Cochrane library. Results: Overall, study quality was moderate to high. Effect sizes were heterogeneous and subgroup analysis was done. Cognitive behavioral therapy (CBT) were effective for pain (ES= -0.35; 95% CI= -0.56, -0.13). Pain education studies measured with NRS and VAS were effective for pain (ES= -0.77; 95% CI= -1.01, -0.52). Publication bias was not detected. Conclusion: This study support the use of psychosocial interventions administered to cancer patients for their pain management. However, more well-designed studies are needed.

• The Journal of the Korea Contents Association
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• v.14 no.3
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• pp.203-214
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• 2014

In this study, a meta-analysis was conducted to investigate the effect of community-based rehabilitation on patients with brain injury by ICF factor in previous studies and examine the application of recent community-based rehabilitation program. Total 15 articles that satisfied the selection criteria were divided by ICF factors to obtain the effect size. Homogeneity and publication bias were tested for those selected papers. As a result, the overall effect size of community-based rehabilitation was 0.22; the effect size by physical function and structure among the ICF factors came to be 0.21; and the effect size of activity and participation was 0.20, indicating a small effect size. The studies involved in a meta-analysis were considered as the absence of heterogeneity and publication bias, which indicates that the results of this study are subjectively reliable. These results well explained the level of change on ICF factors, especially physical function and structure, activity and participation, in other words, the intervention effect of community-based rehabilitation on patients with brain injury.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2361-2368
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• 2015

Objective: To evaluate the diagnostic accuracy of contrast-enhanced ultrasonography (CEUS) in differentiating between benign and malignant enlarged lymph nodes using meta-analysis. Materials and Methods: Pubmed, Embase, SCI and Cochrane databases were searched for studies (up to September 1, 2014) reporting the diagnostic performance of CEUS in discriminating between benign and malignant lymph nodes. Inclusion criteria were: prospective study; histopathology as the reference standard; and sufficient data to construct $2{\times}2$ contingency tables. Methodological quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). Patient clinical characteristics, sensitivity and specificity were extracted. The summary receiver operating characteristic curve was used to examine the accuracy of CEUS. A meta-analysis was performed to evaluate the clinical utility in identification of benign and malignant lymph nodes. Sensitivity analysis was performed after omitting outliers identified in a bivariate boxplot and publication bias was assessed with Egger testing. Results: The pooled sensitivity, specificity and AUROC were 0.92 (95%CI, 0.85-0.96), 0.91 (95%CI, 0.82-0.95) and 0.97 (95%CI, 0.95-0.98), respectively. After omitting 3 outlier studies, heterogeneity decreased. Sensitivity analysis demonstrated no disproportionate influences of individual studies. Publication bias was not significant. Conclusions: CEUS is a promising diagnostic modality in differentiating between benign and malignant lymph nodes and can potentially reduce unnecessary fine-needle aspiration biopsies of benign nodes.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2687-2693
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• 2012

Objective: Passive smoking has been considered as a risk factor of many cancers. To examine whether it might also pose a risk for cervical cancer, we performed a meta-analysis based on published case-control studies. Methods: We searched the PubMed database and references of included studies up to February 10th, 2012 for relevant studies. After two authors independently assessed the methodological quality and extracted data, a meta-analysis was conducted using CMA v2 software. Publication bias was evaluated by funnel plot, using Egger's and Begg's tests. Results: Finally 11 eligible studies yielded, involving 3,230 cases and 2,982 controls. The results showed that women who never smoke but exposed to smoking experience a 73% increase in risk of cervical cancer compared with non-exposed women (OR = 1.73, 95% CI = 1.35 - 2.21, p<0.001). Subgroup and sensitivity analyses indicated this result to be robust. Moderate publication bias was detected by visualing funnel plot, Egger's and Begg's tests. Conclusion: Based on currently available evidence, the findings of this meta-analysis suggests that passive smoking significantly and independently increases the risk of cervical cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7203-7206
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• 2013

Recent studies suggested that the ovarian cancers with negative excision repair cross-complementation group 1 enzyme (ERCC1) expression have a better response to platinum-based chemotherapy than those with positive ERCC1 expression. The objective of this study was to evaluate whether ERCC1 expression is associated with response to platinum-based chemotherapy in ovarian cancers. MEDLINE, PubMed, Web of Science and CNKI databases were used for searching studies relating to ERCC1 protein expression and response to platinum-based chemotherapy in ovarian cancers. Statistical analysis was based on the method for a fixed effects meta-analysis. Pooled odds ratios (ORs) with 95% confidence intervals for ERCC1 protein expression and response to platinum-based chemotherapy were generated. Publication bias was investigated with Begg's test. Five studies involving 306 patients with ovarian cancer were included. Compared to patients with positive ERCC1 expression, those with negative ERCC1 expression had a better response to platinum-based chemotherapy. The pooled OR was 5.264 (95% CI: 2.928-9.464, P < 0.001) and publication bias was not found (P = 0.904). The result was similar in both in Asians and Caucasians (P < 0.001 and P = 0.028, respectively). ERCC1 protein expression status is significantly associated with response to platinum-based chemotherapy in ovarian cancers.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5625-5633
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• 2015

Background: ${\beta}$-catenin plays a crucial role in the progression of breast cancer (BC) and a prognostic role of in BC patients has been widely reported. However, controversy still remains. Materials and Methods: Identical search strategies were used to search relevant literature in electronic databases updated to July 1, 2014. Individual hazard ratios (HRs) and 95% confidence intervals (CIs) were extracted and pooled HRs with 95%CIs were used to evaluate the strength of association between positive ${\beta}$-catenin expression in different subcellular locations and survival results of BC patients. Subgroup and meta-regression analyses were performed to explore heterogeneity. Funnel plots of Begg's and Egger's linear regression test were used to investigate publication bias. Heterogeneity and sensitivity were also assessed. All the work was completed using STATA. Results: A total of 2,204 patients from 12 evaluative studies were finally included. Pooled HRs and 95%CIs suggested that ${\beta}$-catenin expression in cytoplasm/nucleus had an unfavorable impact on both overall survival (OS) (HR: 1.93, 95%CI: 1.40-2.65) and disease free survival (DFS)/ recurrent free survival (RFS) (HR: 1.60, 95%CI: 1.20-2.13) in BC patients. However, here was no significant association between ${\beta}$-catenin expression in the membranes with OS (HR: 0.65, 95%CI: 0.42-1.02) or DFS/RFS (HR: 0.66, 95%CI: 0.38-1.13). Publication bias was absent in all of the four outcomes. Sensitivity analysis revealed that the results of this meta-analysis were robust. Conclusions: Positive ${\beta}$-catenin expression in cytoplasm/nucleus rather than in membrane is a significant prognostic factor in patients with BC who have been surgically treated.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5939-5944
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• 2015

Background: There is still a great deal of controversy with regard to the prognostic role of chemotherapy-induced amenorrhea (CIA) in breast cancer patients. To confirm whether CIA can serve as a useful factor in predicting clinical effects of systemic adjuvant chemotherapy, we performed this meta-analysis. Materials and Methods: Relevant studies were identified using PubMed, and Embase databases. Eligible study results were pooled and summary hazard ratios (HRs) with corresponding confidence intervals (CIs) were calculated. Subgroup analyses and an assessment of publication bias were also conducted. Results: A total of 8,333 patients from 11 published studies were identified through searching the databases. The pooled HRs for disease-free survival (DFS) suggested that CIA was associated with a significant reduction in the risk of recurrence, especially in patients with hormone receptor-positive lesions (overall HR=0.65, 95%CI 0.53-0.80, $I^2=41.3%$). When the five studies reporting the HR for overall survival (OS) were pooled (n=4193), a favorable trend was found (HR=0.69, 95%CI 0.52-0.91, $I^2=51.6%$). No publication bias was observed in this study. Conclusions: This meta-analysis suggests that CIA predicts a better outcome in premenopausal hormone receptor-positive breast cancer patients.