• Proceedings of the Korean Society of Sericultural Science Conference
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• 한국잠사학회 2005년도 제48회 추계 학술연구 발표회
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• pp.25-25
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• 2005

• Molecular & Cellular Toxicology
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• 제1권1호
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• pp.7-12
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• 2005

Proteomics has recently received intense scientific interest after the completion of the Human Genome Project, because this genome-based high technology allows to search new drug targets or diagnostic markers. Many proteome projects including Human plasma proteome projects (HPPP), Human liver proteome projects (HLPP), Human brain proteome projects (HBPP), and Mouse and Rat Proteome Project (MRPP) have been carried out and proteomic analytical techniques have been developed in second dimensional electrophoresis (2-DE) and LC/MS system. This powerful method has been applied in toxicology producing a new term "Toxicoproteomics". In this review, recent proteome projects, proteomic technologies, and toxicoproteomics will be discussed.

• BMB Reports
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• 제37권1호
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• pp.28-34
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• 2004

The discovery of biochemical and cellular functions of unannotated gene products begins with a database search of proteins with structure/sequence homologues based on known genes. Very recently, a number of frontier groups in structural biology proposed a new paradigm to predict biological functions of an unknown protein on the basis of its three-dimensional structure on a genomic scale. Structural proteomics (genomics), a research area for structure-based functional discovery, aims to complete the protein-folding universe of all gene products in a cell. It would lead us to a complete understanding of a living organism from protein structure. Two major complementary experimental techniques, X-ray crystallography and NMR spectroscopy, combined with recently developed high throughput methods have played a central role in structural proteomics research; however, an integration of these methodologies together with comparative modeling and electron microscopy would speed up the goal for completing a full dictionary of protein folding space in the near future.

• Journal of Microbiology and Biotechnology
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• 제16권3호
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• pp.331-348
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• 2006

• Proceedings of the Korean Society of Crop Science Conference
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• 한국작물학회 2007년도 6th OSONG INTERNATIONAL BIO-SYMPOSIUM
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• pp.232.1-232.1
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• 2007

• BMB Reports
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• 제47권3호
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• pp.149-157
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• 2014

The recent dramatic improvements in high-resolution mass spectrometry (MS) have revolutionized the speed and scope of proteomic studies. Conventional MS-based proteomics methodologies allow global protein profiling based on expression levels. Although these techniques are promising, there are numerous biological activities yet to be unveiled, such as the dynamic regulation of enzyme activity. Chemical proteomics is an emerging field that extends these types proteomic profiling. In particular, activity-based protein profiling (ABPP) utilizes small-molecule probes to monitor enzyme activity directly in living intact subjects. In this mini-review, we summarize the unique roles of smallmolecule probes in proteomics studies and highlight some recent examples in which this principle has been applied.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 한국식물생명공학회 2003년도 식물바이오벤처 페스티발
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• pp.92-92
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• 2003

• Proceedings of the Zoological Society Korea Conference
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• 한국동물학회 2001년도 한국생물과학협회 학술발표대회
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• pp.85.2-86
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• 2001

No Abstract, See Full Text

• 대한방사선방어학회:학술대회논문집
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• 대한방사선방어학회 2009년도 춘계 학술발표
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• pp.166-167
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• 2009

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• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 한국식물생명공학회 2006년도 한국육종학회 공동심포지엄 및 학술대회
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• pp.7.1-7.1
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• 2006