• 미생물학회지
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• 제44권4호
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• pp.282-288
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• 2008

혈관이 좁아지거나 막혀서 생기는 허혈은 심장, 뇌, 다리와 같은 인체의 여러 장기에 영향을 미친다. 최근 혈관신생 분야에서 많은 진전이 있어 기존 치료법으로 치료가 되지 않는 허혈성 환자들의 치료 가능성에 대한 기대가 많아졌다. 혈관형성은 여러 개의 인자들과 세포들이 관여하는 복잡한 과정이기 때문에, 한 개의 인자보다는 여러 인자들을 병합하는 요법이 점점 많이 시도되고 있는데, 이런 병합요법의 한 예로 전사인자를 전달하는 전략을 생각할 수 있다. 이에 본 연구에서는 cardiac ankyrin repeat protein (CARP)의 유전자를 대상으로 그 혈관신생 능력을 혈관내피세포에서 조사하였다. 아데노바이러스 벡터 내에 human CARP의 cDNA를 클로닝하여 재조합 아데노바이러스를 제조하였으며, 이를 이용한 유전자 전달실험 결과, CARP 유전자 전달 군에서 유의하게 혈관내피세포의 중식과 모세관 구조 형성, 그리고 vascular endothelial growth factor의 발현 등을 증가시킴을 확인하였다. 본 연구 결과는 CARP가 혈관신생 연구의 새로운 목표 유전자로서 그 기능에 대한 많은 연구가 필요함을 뒷받침해준다.

• 한국콘텐츠학회논문지
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• 제22권4호
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• pp.352-364
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• 2022

환경 개선을 위한 행동의 종류와 요구되는 수준이 다양화되면서 효과적 환경 메시지 개발의 필요성도 늘어나고 있다. 본 연구는 요구 수준이 다른 유형의 행동에 적합한 메시지를 개발하기 위해 메시지 특성인 메시지 프레이밍과 가치지향성을 활용하여 2(메시지 프레이밍: 이익/손실) × 2(가치지향성: 개인/사회) × 2(예방 행동 요구 수준: 높음/낮음) 실험을 실시하였다. 분석 결과, 프레이밍과 행동 요구 수준은 메시지 태도와 행동의도에 주효과를 보였다. 손실 프레이밍보다 이익 프레이밍에서 호의적인 효과가 나타났고, 행동 요구 수준이 낮을 경우 높은 설득 효과가 나타났다. 상호작용 분석 결과, 개인지향 메시지에서는 이익 프레이밍의 행동 의도가 높았고, 사회지향 메시지에서는 프레이밍 간의 차이가 없었다. 또, 행동 요구 수준이 낮을 경우, 개인지향 메시지에서 이익 프레이밍의 메시지 태도가 손실 프레이밍보다 호의적으로 나타났다. 반면 행동 요구 수준이 높을 경우, 사회지향 메시지에서 이익 프레이밍의 메시지 태도가 손실 프레이밍보다 호의적으로 나타났다. 행동 요구 수준에 따른 상호작용 형태의 차이는 있었으나, 개인지향 이익 프레이밍 메시지가 가장 효과적으로 나타났다.

• 한국산림과학회지
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• 제63권1호
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• pp.12-20
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• 1984

본(本) 연구(硏究)는 국산낙엽송재(國産落葉松材)를 이용(利用)한 압체온도(壓締温度)와 시간(時間)에 따른 파티클보오드의 특성(特性)들을 조사(調査)하였다. 결론(結論)을 요약(要約)하면 다음과 같다. 1) 길이와 두께의 비율(比率)이 1:1~35인 비교적(比較的) 불리(不利)한 조건하(條件下)의 chip임에도 불구하고 chip의 표면(表面)이 비교적(比較的) 매끈하게 접착제(接着劑)의 도포(塗布)가 고르게 되고, 공시재(供試材)의 좋은 접착특성(接着特性)이 물리적(物理的) 성질(性質)에 좋은 영향(影響)을 주었다. 2) MOR, MOE, SHA에서 압체시간(壓締時間)이 10분(分)일 때 더욱 좋은 기계적(機械的) 특성(特性)을 보여주고 있다. 3) MOR, IBS, SHA에서 압체시간(壓締時間)이 20분(分)인 경우에 온도(温度)에 따른 그 유의성(有意性)이 인정(認定)되지 않았다. 이는 공시재(供試材)의 노화작용(老化作用)과 수지(樹脂)의 연화작용(軟化作用)이 상호작용(相互作用)하여 일어나는 현상(現狀)으로 보인다. 4) 박리저항(剝離抵抗)에서 압체시간(壓締時間)이 10분(分)일 때 온도(温度)에 따른 내부저항(內部低抗) 값이 증가(增加)되고 있는 것은 중층(中層)에 수지(樹脂)의 적정(適定) 경화온도(硬化温度)가 형성(形成)되는 시간(時間) 때문이다. 5) 흡수(吸水) 팽창(膨脹)에서 압체온도(壓締温度)와 압체시간(壓締時間)에 큰 영향(影響)을 주는데, 이는 열처리(熱處理) 효과(效果)에 따른 공시재(供試材)의 흡수성(吸水性), 이방성(異方性), 불균일성(不均一性) 등(等)이 감소(減)少되어 치수 안전성(安定性)을 유지(維持)시키는데 큰 역할(役割)을 하기 때문이다. 따라서 압체시간(壓締時間)과 압체온도(壓締温度)가 증가(增加)할수록 보다 좋은 치수 안전성(安定性)을 보여 준다.

• 유통과학연구
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• 제14권6호
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• pp.53-63
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• 2016

Purpose - This study examines the effects of the influence strategies on sales representative and headquarter trust, and investigates how sales representative trust plays a mediating role in the relationship between influence strategies and headquarter trust. For these purposes, a structural model which consists of several constructs was developed. In this model, influence strategies that consist of relational influence strategies (information exchange, recommend, promise) and mandatory influence strategies (legal plea, request, threat) were proposed to affect the sales representative trust and in turn, increase the headquarter trust. Thus, this study proposed that sale representative trust plays a core mediating role in the relationship between relational and mandatory influence strategies and headquarter trust in B2B food materials distribution context. Research design, data, and methodology - For these purposes, the authors collected the data from 208 B2B specialized complex agents. We used the 2,200 B2B specialized complex agents which trade with CJ, Ottogi, and Daesang firms and supply food materials to restaurant, school cafeteria, supermarket and traditional market as a sample frame. Once we identified 330 B2B specialized complex agent owners, CEOs, and/or Directors who had agreed to participate in this study, we dropped off a questionnaire at each B2B specialized complex agent and explained the purpose of this study. The survey was conducted from October 1, 2015 to December 15, 2015. A total of 230 questionnaires were collected. Of these collected questionnaires, 28 questionnaires excluded since they had not been fully completed. The data were analyzed using frequency test, reliability test, measurement model analysis, and structural equation modeling with SPSS and SmartPLS 2. Results - First, information exchange, recommendation, and promise of relational influence strategies had positive effects on sales representative trust. The threat of mandatory influence strategies had a negative effect on sales representative trust, but legal plea and request did not have a significant effect on sales representative trust. Second, information exchange and recommendation of relational influence strategies had positive effects on headquarter trust, but promise did not. Also, legal plea, request, and threat of mandatory influence strategies did not have a significant effect on headquarter trust. Third, this findings show that sales representative trust plays a partial mediator between information exchange and headquarter trust, and threat and headquarter trust, and a full mediator between promise and headquarter trust, and recommendation and headquarter trust. Conclusions - The aim of this study was to examine the effects how diverse dimensions of relational and mandatory influence strategies relate to sales representative trust and headquarter trust. To do so, we integrated the influence strategies and the trust transfer theory to hypothesize that various influence strategies increase sales representative and headquarter trust. The findings of this study suggest that headquarter firms should establish and enforce proper influence strategies guidelines to make clear what proper actions sales representatives should implement in relationship with B2B specialized complex agents. Also, relational and mandatory influence strategies must be regarded as a long-term and ongoing strategy that eventually build a long-term orientation with B2B specialized complex agents and guarantee a company's sustainable growth and success.

• 대한영양사협회학술지
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• 제11권2호
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• pp.179-189
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• 2005

The purpose of the study was to investigate the relationships between dietitian’s job satisfaction and perception of barriers to HACCP implementation and food safety/sanitation management performance in school food service. An e-mail survey was conducted to 144 dietitians in Gyeongbuk Province. A response rate was 57.6%(N=83) and data were analyzed using SPSS Windows(ver. 10.0). Dietitians were more satisfied with ‘supervision’ and 'co-workers' than 'pay' and 'promotion.' Dietitians perceived 'lack of teachers' support on student education' and ‘limited availability of facilities/equipment' as the biggest challenges in implementing a HACCP system. A total score of sanitation/safety management performance evaluated by school districts was 92 out of 100. By category, 'safety management' and 'personal hygiene' were rated the highest whereas 'facilities/equipment' and 'HACCP system' categories were rated the lowest. The food sanitation/safety management performance scores were not correlated to dietitian’s job satisfaction, but significantly correlated to dietitian’s perceptions of barriers to HACCP implementation. As dietitians perceived facilities/equipment-related barriers greater, the scores of 'facilities/equipment(p<.01),' 'production process(p<.05),' and 'total score(p<.01)' were significantly lower. The findings suggest that more investment on facilities/equipment are needed for food safety improvement and successful HACCP implementation in school food service. Proper facilities and equipment will make employees monitor CCPs and take corrective actions more easily.

• 대한영양사협회학술지
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• 제21권3호
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• pp.227-240
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• 2015

The purpose of this study was to assess the hygiene status of 145 child-care foodservices, which were newly registered in the Center for the Children's Foodservice Management (CCFSM) in Changwon, Gyeongnam. Sanitary inspection checklist (40 food safety items) of Korea Food and Drug Administration (KFDA) was used by the CCFSM in Changwon, Gyeongnam. Average score from the total safety items in 145 child-care foodservices was 21.41 points out of 40 points. Score gaps between the lower group (71 foodservices, 13.92 points) and higher group (74 foodservices, 28.61 points) showed a significant difference (P<0.001). The top five priorities of sanitary measures needing corrective actions for child-care foodservices were as follows: 'provide hand washing and sanitizing tools, and supply manuals on how to wash hands properly', 'supply record form for access/inspection', 'conduct education for cooks on standards in the selection of sanitizer for raw vegetables and proper methods to wash and sanitize raw vegetables', 'provide a refrigerator and a freezer with installed thermometers and temperature record monitoring logs', 'encourage separation of contamination operating zone and clean zone or conduct training for cooks on ways to prevent cross-contamination by performing work separately by the hour'. For the higher group, most were national/public facilities (83.3%), whereas in the lower group, private facilities (62.1%) were more common than national/public ones (37.9%). Therefore, a significant difference (P<0.001) was detected in the two groups. These private facilities should be supported.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1997년도 한국자동제어학술회의논문집; 한국전력공사 서울연수원; 17-18 Oct. 1997
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• pp.1516-1519
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• 1997

With disseminationof Distributed Control Systems(DCS), the huge amounts of process operation data could have been available and led to figure out process behaviors better on the statistical basis. Until now, the statistical modeling technology has been susally applied to process monitoring and fault diagnosis. however, it has been also thought that these process information, extracted from statistical analysis, might serve a great opportunity for process operation improvements and process improvements. This paper proposed a general methodolgy for process operation improvements including data analysis, backing up the result of analysis based on the methodology, and the mapping physical physical phenomena to the Principal Components(PC) which is the most distinguished feature in the methodology form traditional statistical analyses. The application of the proposed methodology to the Balst Furnace(BF) process has been presented for details. The BF process is one of the complicated processes, due to the highly nonlinear and correlated behaviors, and so the analysis for the process based on the mathematical modeling has been very difficult. So the statisitical analysis has come forward as a alternative way for the useful analysis. Using the proposed methodology, we could interpret the complicated process, the BF, better than any other mathematical methods and find the direction for process operation improvement. The direction of process operationimprovement, in the BF case, is to increase the fludization and the permeability, while decreasing the effect of tapping operation. These guide directions, with those physical meanings, could save fuel cost and process operator's pressure for proper actions, the better set point changes, in addition to the assistance with the better knowledge of the process. Open to set point change, the BF has a variety of steady state modes. In usual almost chemical processes are under the same situation with the BF in the point of multimode steady states. The proposed methodology focused on the application to the multimode steady state process such as the BF, consequently can be applied to any chemical processes set point changing whether operator intervened or not.

• 정보화정책
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• 제21권3호
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• pp.85-101
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• 2014

본 연구에서는 GKMC(정부지식행정시스템)가 그 이용자들이 필요한 지식을 공유하는 데 미치는 요인들을 분석하고 그 결과가 함의하고 있는 정책적 의미들을 읽어내고자 하였다. 이를 위해 먼저 선행연구검토를 통해 CMC품질수준, 공동체일체감, 구조적 사회자본, 관계적 사회자본, 인지적 사회자본 등 총 5개의 지식공유영향요인을 선정하고 분석모형구축, 가설설정, 회귀분석실시 등 일련의 과정을 통하여 위의 5개요인 모두가 GKMC를 통한 지식공유에 긍정적인 영향을 미치는 것으로 나타났다. 가장 큰 영향을 미치고 있는 요인은 공통체일체감이며, CMC품질수준, 사회자본 순이었다. 해당조직의 관리자들은 성공적인 지식공유를 위해 공동체적인 유대감을 형성시키고 사용자들이 GKMC를 편리하게 이용할 수 있도록 지속적으로 모니터링하여 불만을 제거함은 물론이고 발생 가능한 불만들을 예측, 적절한 조치를 취해야 하며, 사회자본들 간의 관계변화추이를 면밀히 살피면서 자유롭고 행복한 조직분위기를 만들어나가야 할 것이다.

• 대한방사선기술학회지:방사선기술과학
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• 제11권1호
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• pp.63-69
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• 1988

In case of occuring the atomic energy accidents the proper medical treatments should be necessary. As the aim of the basic data for protective actions, the present studies were carried out to evaluate the decontamination of radioiodine by the administration of the antithyroid drugs (KI, NaI) and isotonic saline. Some recommended methods of decorporating radioiodine were investigated using 450, NIH-GP mice, each injected intraperitoneally with $1{\mu}Ci$ of $NaI^{131}$ as the internal contamination and treated with 2mg/0.2ml-saline of NaI and 2.6mg/0.2ml-saline of KI as the antithyroid drugs. Accordingly, effects of antithyroid drugs for internal contamination were: 1. Administration of NaI and KI caused to rapidly excrete internal radioiodine as the antithyroid drugs and decrease in whole body retention was reduced than in the saline group. 2. After internal contamination NaI and KI were to be administered for radioprotective effects as quickly as possible. 3. Decrease in body-retention made temporary shifts with enough fluids (water), however, as far as radioprotective effects is concerned, saline was not more significant than in the other group (NaI and KI). 4. Regarding to thyroid protective effects NaI, KI and saline were significant in effectively order.

• 대한교통학회지
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• 제28권6호
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• pp.99-108
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• 2010

최근 들어 기후변화가 국제적으로 최우선 의제로 급부상 하면서 유엔의 최우선 아젠다로 추진하게 되었다. 이에 따라 우리나라에서는 '범지구적 기후변화대응 노력에 동참하고 녹색성장을 통한 저탄소사회 구현, -Low Carbon, Green Growth-' 이란 비전을 국가기본계획으로 발표하였으며, 일환으로 전국 자전거도로 네트워크 구축을 추진하고 있다. 자전거도로 및 인프라 구축을 추진하고 있으나, 길안내를 위한 자전거 도로표지는 고려하고 있지 않은 상황이다. 본 연구에서는 자전거를 위한 안내표지 설치 방안에 대해 연구하였다. 도로표지는 운전자가 이를 인식하고 그 내용을 파악하며 정지 등의 행동을 취하기까지의 거리에 대해 자전거 및 운전자의 자세특성을 고려한 안내표지의 규격 및 설치위치에 대해 이론적 고찰을 하였으며, 그 결과에 따른 실험적 검증을 실시하였다. 자전거 운전자의 전방 시야각에 따른 설치높이를 변경하여 높이에 대해 실험을 실시하였다.