• BMB Reports
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• v.49 no.10
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• pp.529-535
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• 2016

The NLRP3 inflammasome is activated by a variety of external or host-derived stimuli and its activation initiates an inflammatory response through caspase-1 activation, resulting in inflammatory cytokine IL-1β maturation and secretion. The NLRP3 inflammasome activation is a kind of innate immune response, most likely mediated by myeloid cells acting as a host defense mechanism. However, if this activation is not properly regulated, excessive inflammation induced by overactivated NLRP3 inflammasome can be detrimental to the host, causing tissue damage and organ dysfunction, eventually causing several diseases. Previous studies have suggested that mitochondrial damage may be a cause of NLRP3 inflammasome activation and autophagy, which is a conserved self-degradation process that negatively regulates NLRP3 inflammasome activation. Recently, mitochondria-selective autophagy, termed mitophagy, has emerged as a central player for maintaining mitochondrial homeostasis through the elimination of damaged mitochondria, leading to the prevention of hyperinflammation triggered by NLRP3 inflammasome activation. In this review, we will first focus on the molecular mechanisms of NLRP3 inflammasome activation and NLRP3 inflammasome-related diseases. We will then discuss autophagy, especially mitophagy, as a negative regulator of NLPP3 inflammasome activation by examining recent advances in research.

• Journal of Community Nutrition
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• v.2 no.1
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• pp.52-61
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• 2000

Dietary guidelines are a distillation of dietary advice from health professionals to the general public. They are based upon current scientific knowledge about the relationships between diet and disease, nutrients available in the food supply of a country, and the profile of morbidity and mortality in that country. With two different sets of dietary guidelines used for more than an decade in Korea. the necessity of revising dietary guidelines has been raised continuously from academia and research. Funded by a grant from the Health Technology Planing and Evaluation Board. Dietary guidelines for each age group were drafted as a research project and the one for the Korean elderly is as follows: Dietary Guidelines for the korean elderly(draft) - Have a variety of easily digestible foods on time; at least 3 meals a day and some snakes. - Be physically active to maintain appetite and/or ideal body weight. ; maintain a balance between activity and what you eat. -Increase consumption of bean-and dairy-and dairy-products. - Consume enough amounts of fresh dark-green and yellow vegetables and fresh fruits. - Consume adequate amounts of assorted kind of animal foods including fish, meat and poultry. - If you drink alcoholic beverages, limit your intake and, drink enough water and other averages; alcohol may interact with your medication and affect your appetite. Aforementioned draft and related contents are expected to be utilized as a neat base in formulating(or revising) dietary guidelines for Korean by the Government in near future.

• Magazine of the Korean Society of Agricultural Engineers
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• v.24 no.4
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• pp.99-108
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• 1982

This thesis aims to estimate the rainfall runoff from paddy field in a small watershed during irrigation period. When the data observed at the proposed site are not available, the Monthly Runoff Equation of Korean Rivers which was derived from data observed under the following assumptions is used to study the water balance. a. Monthly base flow was assumed as 10. 2mm even if these is no mouthly rainmfall. b. Monthly comsumption of rainfall was ranged from 100 to 2OOmm without relation to the rainfall depth. However, the small watershed which consists mainly of paddy fields encounters severe droughts and accordingly the baseflow is negligible. Under the circumstances the author has developed the following equation called "Flood Irrigation Method for Rainfall Runoff "taking account of the evapotranspiration, precipitation, seepage, less of transportation, etc. R= __ A 7000(1 +F) -5n(n+1)+ (n+1)(Pr-S-Et)] where: R: runoff (ha-m) A: catchment area (ha) F: coefficient of loss (o.o-0. 20) Pr: rainfall (mm) S: seepage Er: evapotranspiration (mm) To verify the above equation, the annual runoff ratio for 28 years was estimated using the Monthly Runoff Equation of Korean Rivers the Flood Irrigation Method and the Complex Hydrograph Method based on meteorological data observed in the Dae Eyeog project area, and comparison was made with data observed in the Han River basin. Consequently, the auther has concluded that the Flood Irrigation Method is more consi- stent with the Complex Hydrograph Method and data observed than the Monthly Runoff Equation of Korean Rivers.

• Nuclear Engineering and Technology
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• v.33 no.2
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• pp.209-224
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• 2001

The SSC-K system analysis code is under development at the Korea Atomic Energy Research Institute (KAERI) as a part of the KALIMER project. The SSC-K code is being used as the principal tool for analyzing a variety of off-normal conditions or accidents of the preliminary KALIMER design. The SSC-K code features a multiple-channel core representation coupled with a point kinetics model with reactivity feedback. It provides a detailed, one-dimensional thermal-hydraulic simulation of the primary and secondary sodium coolant circuits, as well as the balance-of-plant steam/water circuit. Recently a two-dimensional hot pool model was incorporated into SSC-K for analysis of thermal stratification phenomena in the hot pool. In addition, SSC-K contains detailed models for the passive decay heat removal system and a generalized plant control system. The SSC-K code has also been applied to the computational engine for an interactive simulation of the KALIMER plant. This paper presents an overview of the recent activities concerned with SSC-K code model development This paper focuses on both descriptions of the newly adopted thermal hydraulic and neutronic models, and applications to KALIMER analyses for typical anticipated transients without scram.

• Journal of the Korean Institute of Rural Architecture
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• v.22 no.2
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• pp.35-42
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• 2020

The new urbanization is one of prestige growth engines to lead the next generation of China economy, it promotes new sustainable urban development models guided by various planning polices to improve urban livability and sustainability in accommodation with economy, social, and environmental consideration. The expanding urban periphery to rural area should leverages existing assets, infrastructure, local context and plans as a showcase of environmental and economic balance in a responsibly high-density, green community designed to human development and ecological settlement. The Beijing Chaoyang District and Tianjin Binhai area are a strategic advancement in the policy of building one of the most powerful economic regions, the Bohai Rim. Recently released 'Jingjinji development plan' supports various urbanization policies and encourages sustainable developments including 2 significant city center projects which are under way in global attention. The study compared on the characters of development policies and the cutting-edge smart design strategies by which they are applied, the master plan of the Beijing Chaoyang District expansion plan and Tianjin Yujiapu CBD project embrace innovative sustainable technologies.

• KIEE International Transactions on Power Engineering
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• v.4A no.4
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• pp.221-226
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• 2004

As power systems grow more complex and power demands increase, the fault current tends to gradually increase. In the near future, the fault current will exceed a circuit breaker rating for some substations, which is an especially important issue in the Seoul metropolitan area because of its highly meshed configuration. Currently, the Korean power system is regulated by changing the 154kV system configuration from a loop connection to a radial system, by splitting the bus where load balance can be achieved, and by upgrading the circuit breaker rating. A development project applying a 154kV Superconducting Fault Current Limiter (SFCL) to 154kV transmission systems is proceeding with implementation slated for after 2010. In this paper, SFCL is applied to reduce the fault current in power systems according to two different application schemes and their technical and economic impacts are evaluated. The results indicate that both application schemes can regulate the fault current under the rating of circuit breaker, however, applying SFCL to the bus-tie location is much more appropriate from an economic view point.

• Journal of the Korean Home Economics Association
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• v.36 no.3
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• pp.207-224
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• 1998

This study is approach to the Home-Based Work. More specifically, to examine about the families who try to combined home life and income-generation work under the same roof. Families were looking at Home-Based Work as one solution to the work-family crunch. Many research papers have suggested that Home-Based Work provides an effective way to balance the demands of paid employment and family responsibilities. Therefore, this proposed research reviewed the Home-Based Work as they contributed to individual and family satisfactions. The Prupose of this paper is to address issues related to Home-Based Work from the perspective of theory and application in family resource management, also to suggest a conceptual model for family work activities is advanced. This paper is examined concepts related to Home-Based Work employment that could be used to frame and describe the empirical study are specified. This paper was informed by analyses of data from project NE-167. "At-Home Income Generation: Impact on Management, Productivity, and Stability in Rural/Urban Families". The results from this paper will be helpful in enhancing the stability and satisfaction of families who worked in Home-Based Work.ased Work.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.199-200
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• 2006

PM recent developments focus on increasing this technology's competitiveness when compared to wrought materials. Warm compaction allows the replacement of a double press double sinter process with a single warm press and sintering step, thus allowing cost and time savings. Moreover there are added benefits to consider such as reducing work in process and lessening part's logistics cost. This paper presents a successful industrial trial to replace a double press-double sinter process with a warm die compaction and sintering process. The part chosen was a high performance gear containing 0,9% wt. carbon. Sintering was conducted in a belt furnace at $1120^{\circ}C$ in a nitrogen rich atmosphere with rapid cooling process in order to obtain a quasi fully martensitic structure with a minimum of 700HV0,1 and 450HV10 after annealing. The balance between properties and cost is favoured by the use of a singular lubricant developed in a Eureka frame project together with POMETON S.A. and die warm compaction. Warm compaction is only needed to be effective on the gear teeth, in order to achieve the required properties. Therefore only the die is actually heated. This simplified system avoids flow rate problems typically involved when using more elaborate warm compaction equipments.

• Asia pacific journal of information systems
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• v.20 no.1
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• pp.101-125
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• 2010

This paper uses the status inconsistency theory to identify factors related to team members' (dis)satisfaction with the composition of virtual IT project teams in order to predict their turnover intentions. Our approach is based on the premise that virtual teams, although increasingly popular among global organizations, create an environment replete with cultural and functional diversity. Yet, a paradox exists: increasing diversity in virtual teams maximizes the creation and use of organizational knowledge while simultaneously increasing dissatisfaction and turnover. This is a critical issue in the formation and management of virtual teams. Therefore, we investigate how team members' perceptions of differences among themselves (i.e. foreignness) impact the stability of team membership, leading to what we describe as a 'liability of foreignness.' Findings indicate that a member's perception of foreignness has a detrimental effect on satisfaction with his or her team members while satisfaction is likely to decrease turnover intention. This may be an implication that managers need to maintain a balance in order to discourage member turnover and the loss of key players.

• Proceedings of the KIEE Conference
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• summer
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• pp.421-423
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• 2004

As power system grows more complex and power demands increase, the fault current tends to gradually increase. In the near future, the fault current will exceed a circuit breaker rating for some substations, which is an especially important issue in the Seoul metropolitan area because of its highly meshed configuration. Currently, the Korean power system is regulated by changing the 154kV system configuration from a loop connection to a radial system, by splitting the bus where load balance can be achieved, and by upgrading the circuit breaker rating. A development project applying 154kV Superconducting Fault Current Limiter(SFCL) to 154kV transmission systems is proceeding with implementation slated for after 2010. In this paper, the expected price of SFCL in order to assure the economic feasibility is evaluated comparing with upgrading cost of ciui.1 breakers. The results show that the SFCL should be developed under seven times of price of circuit breaker to be competitive against upgrading circuit breakers.