• Proceedings of the Korean Society of Applied Pharmacology
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• 2001.11a
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• pp.41-76
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• 2001

Rheumatoid arthritis is an incurable chronic inflammatory and destructive arthopathy that affects 1% of the population world-wide. It has substantial personal, social and economic costs. The long-term prognosis is poor: 80 percent of affected patients will become disabled within 20 years after onset of disease. Medical costs of rheumatoid arthritis average ∼$ 6000 (US) per patient (1), Current antirheumatic drugs have limited efficacy and many side effects and more importantly they do not improve the long-term prognosis of rheumatoid arthritis (2). After a decade of few notable advances in therapy, several biological response modifiers that target pathophysiological processes in the disease have now emerged in the clinic. These new drugs are termed biological agents, and although information about their use in the clinic is still limited to short term treatment, they appear to have the ability to modify disease progress. In addition, COX-2 selective agents have now been approved that have comparable efficacy with standard NSAIDs, but fewer gastrointestinal side effects (3). Thus today many more therapeutic options are suddenly open to patients that even five years ago had little hope of relief from chronic pain and inflammation.

• Korean Journal of Remote Sensing
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• v.2 no.1
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• pp.35-47
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• 1986

The progress in computer technology has significantly improved the capabilities of the microcomputer image processing systems and brought down their hardware costs. This on-going trend of technological development seems to bring further substantive improvements in microcomputer image processing and decreasing hardware costs. The technical development in microcomputer image processing system including VLSI technology, semiconductor memory, disk and tape storage, and image display subsystems have been reviewed and their future trend have been projected. The impact of this technology to the development of image processing has been assessed in the time period of immediate future (2-3 years) and near future (5 years).

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.899-904
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• 2007

Improvement projects has been progressed for railway electrification and double track line in the conventional line as well as high speed line for the high speed and large transportation capability of railway. Especially, many variable operation plans are possible such as interaction between high speed line and conventional line and operation of tilting train due to the electrification of the conventional line. Railway electrification is more energy efficient and environmentally-friendly, but it has some problems such as an enormous initial construction and maintenance costs and electrical accidents. Therefore, the more intensive research will be progressed about railway electrification effectiveness for the continuous electrification project. So, we analyzed railway electrification effectiveness about the energy side using annual operation data of electric car and diesel car. The energy side was divided into energy costs and national energy consumption for analyzing electrification effectiveness about entire line and specific line. We verified advantage of energy costs and national energy consumption in this paper and this result will contribute to the progress of the continuous electrification project and the more efficient operation ways in electrification line

• The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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• v.19 no.2
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• pp.67-81
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• 1990

The objective of this is to develop a practical software package to calculate annual energy consumption of HVAC (Heating Ventilating, and Air Conditioning) System in a building. It can quickly estimate loads and energy consumption, and have a function of economic analysis through the estimation of operating cost. Techniques of save energy consumption used in a building are necessary from the stage of design process to operation. The single most significant task is on HVAC Systems. Their installation costs, and related operating costs have enormous influence upon initial and maintenance costs. HVAC designers and engineers now have a wide variety of software choices available, but only a few of them have been developed in this country and no source program has been disclosed. Neither load culculation nor estimation of energy consumption is systematically made by the domestic HVAC design firms. Even though computer improved over the years with a trend of large scale load calculation and system selection through simulaion, the utilization of software nowadays does not make good progress due to lack of working environment. Therefore, it is necessary to develop a practical software package with which load calculation can be made with ease and kind manner. This study concerns the development of a software package which makes it possible to design HVAC system and save energy consumption in operation. The algorithm used in this program is a Modified Bin Method widely known as a simplified energy analysis means.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2022.11a
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• pp.215-216
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• 2022

Profit, the performance of an apartment development project, is directly affected by the sales ratio, unit sale price, financial costs, land costs and construction costs. However, these factors fluctuate in response to changes in the environment, including various stake holders, and the profits fluctuate as a result. In order to ensure that profits are managed within target levels, these factors must be able to be predicted, controlled and monitored and managed up to the start, sale, and end stages of the project. The purpose of this study is to develop a profit risk management model for apartment development projects. The results of this study will contribute to the establishment of academic basis for the dynamic management of project profits that fluctuate with time and environment. And in practice, it will help project developers manage their business revenue to the proper level. In addition, the risks that occur from time to time can be identified quantitatively and visually, and it is expected that it will be easier to derive consensus points for smooth business progress by reducing conflicts of interest among stakeholders.

• Proceedings of the KSR Conference
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• 2001.05a
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• pp.66-71
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• 2001

Most payments in domestic construction are issued in lumpsum unit price contracts according to the completed construction rate. This method generates problems in losing time and increased costs for the owner and contactor. In overseas projects, payments are issued in accordance to completed milestones. The milestones themselves base on the original schedule and allow effective schedule management on the tasks. In domestic construction, however, introduction of milestone payments requires enhanced management capability of owners and contractors. Hence, this study investigating how to activate schedule management devices to analyze progress payments in domestic construction.

• East Asian Economic Review
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• v.18 no.3
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• pp.215-251
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• 2014

This study explores the main causes that have led Japan to conclude an FTA with ASEAN. This paper appraises Japan-ASEAN relations and shows that closer relations between Japan and ASEAN have provided momentum for the launch of Japan's FTAs with ASEAN. Consequently, this paper explores the origins and progress of Japan-ASEAN FTA, as well as the strategies and initiatives embraced by Japan in its FTA negotiations with ASEAN. By examining the domestic, regional, and global factors that led to the launch of the Japan-ASEAN FTA, this paper concludes that the strategies adopted were primarily aimed at its main rival, China. The rivalry has resulted in both positive and negative consequences for East Asian Regional economic environment. The negative consequences include the creation of a "spaghetti bowl", which increases costs for Japanese firms operating abroad, and "slows down the progress of the creation of an effective single regional institution".

• Proceedings of the KIEE Conference
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• 2004.05a
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• pp.89-91
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• 2004

Recently Neural Network techniques have widely used in adaptive and learning control schemes for production systems. However, generally it costs a lot of time for learning in the case applied in control system. Furthermore, the physical meaning of neural networks constructed as a result is not obvious. And in practice since it is difficult to the PID gains suitably lots of researches have been reported with respect to turning schemes of PID gains. A Neural Network-based PID control scheme is proposed, which extracts skills of human experts as PID gains. This controller is designed by using three-layered neural networks. The effectiveness of the proposed Neural Network-based PID control scheme is investigated through an application for a production control system. This control method can enable a plant to operate smoothy and obviously as the plant condition varies with any unexpected accident. This paper goal is convergence speed progress about applied gain of PID controller using the neural networks.

• International Journal of Computer Science & Network Security
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• v.24 no.3
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• pp.29-37
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• 2024

Resorting to electronic arbitration to resolve disputes in international trade contracts is the most important reflection of technological progress on the reality of international commercial arbitration. Electronic is a modern image of traditional arbitration, and this type of arbitration provides many advantages that are not provided by any legal system for resolving disputes, including speed, effectiveness and lower costs. What will this development produce? Through technical progress in the means of communication, it has become conceivable that international trade dealers agree to arbitration via electronic means of communication, followed by the completion of the arbitration process via the Internet, leading to the issuance of the electronic arbitration award in an electronic manner as well.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.524-524
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• 2006

For decades, the pursuit of volume commercialization of low-power reflective displays with a paper-like look has been an unfulfilled dream. While steady technical progress was made throughout the late 1990s, there were still no volume products incorporating electronic paper displays (EPD) on the market. Now, microencapsulated electrophoretic display technology, also called electronic ink, has moved into volume production with a frontplane laminate (FPL) display component called E Ink Imaging Film™. This film is coated roll to roll on a flexible plastic substrate and integrated into a display module. Today, all-plastic segmented displays are being shipped as well as displays with electronic ink FPL being driven by glass TFT backplanes. A roadmap to active matrix flexible electrophoretic displays is being enabled by rapid technical progress on flexible TFT backplanes by a variety companies. Each of the approaches to these backplanes and flexible active matrix displays has different advantages for the various market segments being pursued including large format flexible displays for e-news and other reader applications, rollable displays for compact readers, and high resolution small format displays up to 400 ppi that can have fully integrated drive electronics to reduce size and drive down costs. Backplane approaches include Si on plastic, organic transistors on plastic, and Si transistors on flexible stainless steel substrate. Progress is also being made on next generation inks, including more reflective inks with higher contrast ratios. A full color 6 inch, 170 pixel per inch (PPI) active matrix display using a newer generation ink has been developed and this will be described and demonstrated. Large format segmented flexible displays will also be described.