• Nuclear Engineering and Technology
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• 제42권2호
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• pp.163-174
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• 2010

As pointed out in the OECD BEMUSE Program, when a high computation time is taken to obtain the relevant output values of a complex physical model (or code), the number of statistical samples that must be evaluated through it is a critical factor for the sampling-based uncertainty analysis. Two alternative methods have been utilized to avoid the problem associated with the size of these statistical samples: one is based on Wilks' formula, which is based on simple random sampling, and the other is based on the conventional nonlinear regression approach. While both approaches provide a useful means for drawing conclusions on the resultant uncertainty with a limited number of code runs, there are also some unique corresponding limitations. For example, a conclusion based on the Wilks' formula can be highly affected by the sampled values themselves, while the conventional regression approach requires an a priori estimate on the functional forms of a regression model. The main objective of this paper is to assess the feasibility of the ACE-RSM approach as a complementary method to the Wilks' formula and the conventional regression-based uncertainty analysis. This feasibility was assessed through a practical application of the ACE-RSM approach to the LOFT L2-5 LBLOCA PCT uncertainty analysis, which was implemented as a part of the OECD BEMUSE Phase III program.

• Journal of Radiation Protection and Research
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• 제34권2호
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• pp.69-75
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• 2009

교육적 목적으로 감마선 검출기 계통의 특성에 대한 정보를 세밀하게 얻기 위하여, Delphi코드를 이용하여 전 에너지 흡수 피크 스펙트럼을 편리하게 분석할 수 있는 그래픽 사용자 인터페이스 방식의 컴퓨터 프로그램을 개발하였다. 피크는 4개의 비선형 모양함수를 사용하여 최소제곱법으로 적합하였다. 이들 4개의 비선형함수 속에 들어있는 12개의 계수값들을 사용자 인터페이스 화면에서 결정하는 과정을 상세히 서술하였다. 개발된 프로그램을 HPGe 검출기에서 측정된 1 $\mu$Ci 밀봉 점선원 $^{137)Cs$ 661KeV 감마선의 피크분석에 적용하여 계수값 탐색의 예를 예시하였다.

• 정보과학회 논문지
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• 제41권12호
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• pp.1018-1025
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• 2014

반환 지향 프로그래밍 공격(ROP)은 프로그램에 존재하는 반환 명령어로 끝나는 코드 조각들을 조합하여 가젯을 만들고, 연속적으로 실행하여 스택의 내용을 조작함으로써 프로그램의 제어권을 가져오는 공격이다. 이에 대한 기존 방어기법은 높은 실행 오버헤드와 바이너리 증가 오버헤드를 갖거나, 적용 범위의 제한이 있는 문제점이 있다. 본 논문에서는 기존 기법의 문제점을 갖지 않으면서 성능 및 바이너리 크기 증가 측면에서 효율적인 방어 기법인 zero-sum defender를 제안한다. 반환 지향 프로그래밍 공격은 정상적인 프로그램의 흐름과 다르게, 함수 호출 명령어가 실행되지 않고 여러 반환 명령어가 실행되는 실행 특성을 가진다. 제안 기법은 이러한 특성을 이용하여 프로그램 실행 흐름이 반환 지향 프로그래밍 공격에 의해 오용되는지 모니터링하여 방어 기능을 수행한다. 실제 공격 모델에 대한 실험을 통해 방어 기법의 효용성을 확인하였고, 벤치마크 실험을 통해 약 2%의 성능 오버헤드와 약 1%의 바이너리 크기 증가만으로 방어가 이루어짐을 확인하였다.

• 한국의학물리학회지:의학물리
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• 제24권4호
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• pp.259-264
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• 2013

방사선치료의 선량계산을 위해 Geant4 기반의 전산모사를 실행할 때 필요한 응용 프로그램을 개발 하였다. DICOM의 헤더 부분을 분석하여 각종 파라메터를 구하였다. 특히 배포 판에서의 문제점을 모두 해결하기 위해 클래스를 새로 정의하였다. 따라서 국내에 설치된 대부분의 DICOM 파일을 변환 할 수 있게 되었다. 픽셀 데이터의 변환 값을 확인하는 프로그램을 개발하여 정확성을 비교 하였다.

• 한국시뮬레이션학회논문지
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• 제7권2호
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• pp.17-32
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• 1998

The flow fields in Gas Bubble Driven Circulation Systems were numerically analyzed. In various gas flow rate and bubble size, the flow characteristics were predicted. Eulerian-Eulerian approach was used for the formulation of both the continuous and dispersed phases. The modification of the general purpose computer program PHOENICS code was employed to predict the mean flow fields, turbulent characteristics, gas dispersion, volume fraction. The predicted shows very satisfactory agreement with experimental results for all regions of ladle. The results are of interest in the design and operation of wide variety of material processing.

• 한국압력기기공학회 논문집
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• 제9권1호
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• pp.62-69
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• 2013

A probabilistic assessment code, PRO-LOCA ver. 3.7 which was developed in an international co-operative research program, PARTRIDGE was evaluated by conducting sensitivity analysis. The effect of some variables such as simulation methods (adaptive sampling, iteration numbers, weld residual stress model), crack features(Poisson's arrival rate, maximum numbers of cracks, initial flaw size, fabrication flaws), operating and loading conditions(temperature, primary bending stress, earthquake strength and frequency), and inspection model(inspection intervals, detectable leak rate) on the failure probabilities of a surge line nozzle was investigated. The results of sensitivity analysis shows the remaining problems of the PRO-LOCA code such as the instability of adaptive sampling and unexpected trend of failure probabilities at an early stage.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 1998년도 유체기계 연구개발 발표회 논문집
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• pp.27-32
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• 1998

This paper presents the development of a two-dimensional model for investigating the fluid flow in water jet and calculating the velocity and pressure distributions. The mathematical formulation as a standard k-$\epsilon$ model was solved employing a general thermofluid-mechanics computer program, PHOENICS code, which is based on the Semi-Implicit Method Pressure Linked Equations(SIMPLE) algorithm. The developed code was applied to water jet design to determine the nozzle size, and investigated the effect of the change of nozzle location. Calculated results showed that the flow pattern is not changed as the change of nozzle location.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2003년도 춘계학술발표회
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• pp.167-172
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• 2003

Place that have cutout inner bottom and girder and floor etc. in hull construction absence is used much, and this is strength in case must be situated, but establish in region that high stress interacts sometimes fatally in region that there is no big problem usually by purpose of weight reduction, a person and change of freight piping etc.. Because cutout's existence gnaws in this place, and, elastic buckling strength by load causes large effect in ultimate strength. Therefore, perforated plate elastic buckling strength and ultimate strength is one of important design criteria which must examine when decide structural elements size at early structure design step of ship. Therefore, and, reasonable elastic buckling strength about perforated plate need design ultimate strength. Calculated ultimate strength change several aspect ratioes and cutout's dimension. and thickness in this investigation. Used program applied ANSYS F.E.M code transformation finite element law that is mediocrity finite element analysis code.

• 대한기계학회논문집B
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• 제38권1호
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• pp.71-79
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• 2014

본 연구에서는 가압경수로 주요 기기의 고정밀 열수력 해석을 위한 CUPID(Component Unstructured Program for Interfacial Dynamics) 코드의 압력장 해석을 위한 이중공액구배법(Bi-Conjugate Gradient) 알고리즘의 병렬화를 SMP(Symmetric Multi Processing) 시스템에서 고찰한다. 비압축성 후향계단 유동문제의 병렬해석을 다양한 격자 조밀도를 가지는 격자들에 대하여 세 가지 대표적인 병렬 기법(MPI, OpenMP, 하이브리드)을 적용하여 병렬성능 비교를 수행하였다. 병렬처리 성능은 해석 문제의 크기뿐만 아니라 캐쉬 메모리 크기에도 영향을 받으므로, 전체 계산량이 매우 적거나 개별 쓰레드에 사용되는 메모리가 캐쉬 메모리보다 매우 큰 경우에는 병렬화에 의한 성능 향상이 낮음을 확인하였다. 또한, 문제 크기에 상관없이 MPI 기법이 OpenMP보다 성능이 우수했으며, 상대적으로 적은 쓰레드를 사용한 경우엔 하이브리드 기법이 가장 우수한 성능을 보였다.

• Interdisciplinary Bio Central
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• 제4권1호
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• pp.2.1-2.7
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• 2012

Introduction: Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from ${\varepsilon}$-N-acetyl lysine amino acids of histone proteins. Their action is opposite to that of histone acetyltransferase that adds acetyl groups to these lysines. Only few HDAC inhibitors are approved and used as anti-cancer therapeutics. Thus, discovery of new and potential HDAC inhibitors are necessary in the effective treatment of cancer. Materials and Methods: This study proposed a method using support vector machine (SVM) to classify HDAC8 inhibitors and non-inhibitors in early-phase virtual compound filtering and screening. The 100 experimentally known HDAC8 inhibitors including 52 inhibitors and 48 non-inhibitors were used in this study. A set of molecular descriptors was calculated for all compounds in the dataset using ADRIANA. Code of Molecular Networks. Different kernel functions available from SVM Tools of free support vector machine software and training and test sets of varying size were used in model generation and validation. Results and Conclusion: The best model obtained using kernel functions has shown 75% of accuracy on test set prediction. The other models have also displayed good prediction over the test set compounds. The results of this study can be used as simple and effective filters in the drug discovery process.