• Archives of Plastic Surgery
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• 제48권1호
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• pp.10-14
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• 2021

Soft tissue filler injections are widely used due to their immediate effects, predictable results, and high stability. However, as the use of soft tissue filler injections has increased, various complications have been reported. We report a life-threatening complication in a patient who developed sepsis and necrotizing fasciitis. A 45-year-old woman presented with right leg pain and discharge from the labia majora. The patient had received a soft tissue filler injection of unknown composition 1 year earlier and had recently undergone incision and drainage for an inflammatory cystic nodule. Antibiotic treatment was administered for cellulitis, but the infection progressed to necrotizing fasciitis and sepsis. Fasciotomy and intensive care unit treatment improved the systemic infection, but the soft tissue filler injection site did not respond to treatment for 1 month. Thus, the injection site was covered with a pedicled vertical rectus abdominis musculocutaneous flap after wide excision. The area of skin necrosis on the leg was covered with split-thickness skin grafts. Infections occurring after soft tissue filler injections are related to biofilms, and treatment is sometimes difficult. Therefore, although soft tissue filler injections have a favorable safety profile, it is important to be aware of the risk of life-threatening complications.

• 한국정밀공학회지
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• 제14권11호
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• pp.58-68
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• 1997

The residual stresses in injection-molded plastic parts can be divided into two, i.e., the flow-induced residual stress produced in flowing stage and the thermally-induced residual stress produced in cooling stage. Especially, the main source for the defect in the final parts, such as warpage, is known to be the thermally-induced stresses. For the freely quenched samples the structures of residual stresses and bire-fringence have been investigated by many researchers extensively. However, the boundary condition for free quenching was found to be improper to study actual injection molding process. In the present study a datailed structure of the residual stresses and birefringence produced under constrained quenching has been investigated experimentally. In constrained quenched samples a similar pattern but much less stress values than that for the freely quenched samples has been found in the case of the thickness of 1.0 mm. Howvere, in the case of the thickness of 4.0mm, totally different stress profile has been found experimentally. Suprisingly uniform birefringence throughout whole thickness has been found for all the cases of constrained quenching. Finally, to explain the mechanism to produce the final residual stresses and bire-fringence some preliminary numerical results including free volume theory have been introduced briefly.

• Korea-Australia Rheology Journal
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• 제14권3호
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• pp.107-114
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• 2002

Residual stress distribution in injection molded short fiber composites is determined by using the layer-removal method. Polystyrene is mixed with carbon fibers of 3% volume fraction (4.5% weight fraction) in an extruder and the tensile specimen is injection-molded. The layer-removal process, in which removing successive thin uniform layers of the material from the surface of the specimen by a milling machine, is employed and the resulting curvature is acquired by means of an image processing. The isotropic elastic analysis proposed by Treuting and Read which assumes a constant Yaung’s modulus in the thickness direction is one of the most frequently used methods to determine residual stresses. However, injection molded short fiber composites experience complex fiber orientation during molding and variation of Yaung’s modulus distribution occurs in the specimen. In this study, variation of Yaung’s modulus with respect to the thickness direction is considered for calculation of the residual stresses as proposed by White and the result is compared with that by assuming constant modulus. Residual stress distribution obtained from this study shows a typical stress profile of injection-molded products as reported in many literatures. Young’s modulus distribution is predicted by using numerical methods instead of experimental results. For the numerical analysis of injection molding process, a hybrid FEM/FDM method is used in order to predict velocity, temperature field, fiber orientation, and resulting mechanical properties of the specimen at the end of molding.

• Elastomers and Composites
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• 제48권4호
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• pp.300-305
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• 2013

사출성형에서 성형수축은 피할 수 없는 현상이다. 따라서 성형수축을 줄이기 위한 연구가 필요할 뿐만 아니라 성형수축의 특성을 명확히 파악하는 것이 필요하다. 본 연구에서는 유리섬유로 보강된 폴리카보네이트를 이용하여 2.5차원형상인 환상형상의 시편에서 보이는 성형수축 현상을 조사하였다. 환상시편은 외경의 크기와 두께를 달리하여 설계하였다. 성형조건은 수지온도, 보압시간 및 보압크기를 변수로 설정하였다. 여러 성형조건으로 성형된 시편에서 내경과 외경의 크기가 변하는 양상에 대해서 분석하였다. 성형된 시편의 외경과 내경의 치수는 금형의 치수보다 작게 나타났다. 시편의 외경이 클수록, 그리고 시편의 두께가 두꺼울수록 수출율은 작게 나타났다. 또한 게이트의 위치에 따라 수축의 크기가 방향성을 보였다. 따라서 성형된 시편은 원형이 아니라 타원형으로 나타났고 게이트 방향으로 내경과 외경이 가장 큰 수축을 보였다. 수축된 제품의 형상조절을 위해서는 게이트 설계와 같은 금형설계가 중요하다고 판단된다.

• Molecules and Cells
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• 제39권10호
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• pp.728-733
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• 2016

Mesenchymal stem cells (MSCs) effectively reduce airway inflammation and regenerate the alveolus in cigarette- and elastase-induced chronic obstructive pulmonary disease (COPD) animal models. The effects of stem cells are thought to be paracrine and immune-modulatory because very few stem cells remain in the lung one day after their systemic injection, which has been demonstrated previously. In this report, we analyzed the gene expression profiles to compare mouse lungs with chronic exposure to cigarette smoke with non-exposed lungs. Gene expression profiling was also conducted in a mouse lung tissue with chronic exposure to cigarette smoke following the systemic injection of human cord blood-derived mesenchymal stem cells (hCB-MSCs). Globally, 834 genes were differentially expressed after systemic injection of hCB-MSCs. Seven and 21 genes, respectively, were up-and downregulated on days 1, 4, and 14 after HCB-MSC injection. The Hbb and Hba, genes with oxygen transport and antioxidant functions, were increased on days 1 and 14. A serine protease inhibitor was also increased at a similar time point after injection of hCB-MSCs. Gene Ontology analysis indicated that the levels of genes related to immune responses, metabolic processes, and blood vessel development were altered, indicating host responses after hCB-MSC injection. These gene expression changes suggest that MSCs induce a regeneration mechanism against COPD induced by cigarette smoke. These analyses provide basic data for understanding the regeneration mechanisms promoted by hCB-MSCs in cigarette smoke-induced COPD.

• 한국분무공학회지
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• 제21권3호
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• pp.155-161
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• 2016

Injected fuel pressure waves of a common rail injector with various current profiles supplied to the injecor were measured using Bosch method. In order to drive the common rail injector, the current in the solenoid should be controlled using what is known as a peak and hold pattern, which consists of a high current level with a short time duration (peak) in the first step and a low current level with a long time duration (hold) in the subsequent step. The current profile can be shaped by swithcing an injector driving power source with the peak and hold waves. The capture, compare and PWM (CCP) pin in the microprocessor was used to generate the combined peak and hold waves. The PWM square wave generated from the CCP pin has a duty ratio of 100% for the peak current and 10% or 30% for the hold pattern. Five patterns of the current profile were generated by combining the peak and hold wave. The common rail pressure is controlled at 75, 100, and 130 MPa. As the fuel rail pressure increases, the variations of the measured fuel injection pressure wave according to the current profiles decrease.

• 대한기계학회논문집
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• 제19권12호
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• pp.3360-3371
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• 1995

Hydrodynamic characteristics of a stratified flow at a Y-junction were examined analytically. Gas is supplied through the main horizontal channel and liquid is introduced into the gas stream from the Y-shaped bottom branch. Analysis was performed with irrational flow and inviscid fluid assumptions. The Stokes' inverse transformation technique was adopted to convert the real x-y plane into the x-.psi. plane. The potential flow equation was solved numerically in the transformed (x-.psi.) plane and the interface profile, pressure distribution and the streamlines were obtained. The effects of the inlet conditions, injection angle and the gravity on the flow characteristics were also examined. To check the validity of the present method, the previous resultant the two-dimensional obtuse wedge flow was compared. The inverse transformation technique turned out to be also very useful to predict the hydrodynamic characteristics of a stratified flow with the pressure variation at a Y-shaped mixing junction.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2002년도 춘계학술대회 논문집
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• pp.22-27
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• 2002

The existing compressor steel seal used in automotive air-conditioner has the problem of oil leakage and the deterioration in shielding performance, due to the abrasion and the corrosion of the material. A new type of polymer resin seal is studied in the research. The polymer resin seal has the characteristics of high anti-abrasiveness and anti-corrosiveness, which can overcome the deflects of the steel seal. In addition, the seal needs lower manufacturing cost and is appropriate to mass production, because it is made by the injection molding method requiring no mechanical processing. The profile generation program for seal mold has been developed using the gradient method, and the molding characteristics of the seal have analyzed through the flow analysis and the warpage analysis. The program has been verified by comparing the analysis results with the measured data of the test product. The research might be said to provide the basic method to produce the polymer resin seals with various types and dimensions.

• 한국공작기계학회논문집
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• 제11권5호
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• pp.81-87
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• 2002

The existing compressor steel seal used in automotive air-conditioner has the problem of oil leakage and deterioration in shielding performance, due to the abrasion and corrosion of the material. A new type of polymer resin seal studied in this research has the characteristics of high anti-abrasiveness and anti-corrosiveness, which can oversome the defects of the steel seal. In addition, the seal needs lower manufacturing cost and is appropriate to mass production, because it is made by the injection molding method requiring no mechanical processing. The profile generation program for seal mold has been developed using the gradient method, and the molding characteristics of the seal have analyzed through the flow analysis and the warpage analysis. The program has been verified by comparing the analysis results with the measured data of the test product. The research might be said to provide the basic method to produce the polymer resin seals with various types and dimensions.

• 동력기계공학회지
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• 제12권6호
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• pp.78-82
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• 2008

Plastic gears are more and more widely used in many industrial machine elements. Plastic gear has higher properties such as light weight, wear resistance, and vibration absorbing ability than metallic gears. But, in case of using an inaccurate plastic gear, its tooth breakage happen and fatigue life is shortened due to increase of applying load and temperature rising on the tooth flank. Inaccuracy of plastic gears such as pitch circle roundness and tooth profile generates vibration and noise. In this study, an internal plastic gears which is molded by a new injection mold structure are developed. The new mold structure is called the HR3P(hot runner type 3plate mold) that has an improved runner system in order to have good filling balance. As a result from this study, an internal gear with very accurate roundness was developed by using design of experiment.