• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2000.04a
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• pp.120-129
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• 2000

As structure-soil interaction analysis for the seismic analysis of structures requires a nonlinear analysis of a structure-soil system considering the inelastic characteristics of soil layers nonlinear analyses of the foundation-soil system with the horizontal excitation were performed considering the nonlinear soil conditions for the nonlinear seismic analysis of structures. Stiff soil profile of SD and soft soil profile of SE specified in UBC were considered for the soil layers of a foundation and Ramberg-Osgood model was assumed for the nonlinear characteristics of soil layers. Studies on the changes of dynamci stiffnesses and damping rations of surface and embedded foundations depending on foundation size soil layer depth and piles were performed to investigate the effects of the nonlinear soil layer on the horizontal and rotational dynamic stiffnesses and damping ratios of the foundation-soil system According to the study results nonlinear prperties of a soil laryer decreeased horizontal and rotational linear stiffnesses and increased damping ratios largely Effects of foundation size soil layer depth and piles were also significant suggesting the necessity of nonlinear seismic analyses of structures.

• Proceedings of the KIEE Conference
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• 2004.11c
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• pp.114-116
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• 2004

The temperature profile control issue in the resistive welder for the electronic parts is discussed. The average current of the welder tip depends on the phase(on-time) of the AC power and the tip temperature maintains or increases/decreases depending on the integral of the current square and heat loss, The basic PID control algorithm with thermo-couple feedback is difficult to track the temperature profile for various parts and optimal gain changes much. So constant gain PID algorithm is not enough to cover various electronic parts welding and a Fuzzy-PID automatic gain tuning algorithm is devised and added to conventional PID algorithm and this hybrid control architecture is implemented and the experimental results are shown.

• Journal of Biosystems Engineering
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• v.21 no.3
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• pp.293-305
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• 1996

Effects on the tractor vibrations of tread, wheelbase and axle load distribution were analyzed by using mathematical models of tractor and random road surface. A 4 degrees of freedom tractor model was developed to predict the bounce, pitch and roll motions of tractor. The front axle which is constrained to roll with respect to tractor body was also included in the model. A random road profile was generated and used as an excitation input to the tractor. Output vibrations of the model were predicted and analyzed by a computer simulation method. In general, longer tread tends to reduce rolling and longer wheelbase does bouncing and pitching motions. Tractor vibrations were minimum when the ratio of front to rear axle loads was in the range of 30:70-35:65. Sensitivity analysis showed that rolling and pitching motions most sensitively varied with changes in tread and wheelbase while bouncing motion did with the location of mass center.

• BMB Reports
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• v.39 no.4
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• pp.457-463
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• 2006

Insulin resistance is commonly observed in patients prior to the development of type 2 diabetes and may predict the onset of the disease. We tested the hypothesis that impairment in insulin stimulated glucose-disposal in insulin resistant patients would be reflected in the gene expression profile of skeletal muscle. We performed gene expression profiling on skeletal muscle of insulin resistant and insulin sensitive subjects using microarrays. Microarray analysis of 19,000 genes in skeletal muscle did not display a significant difference between insulin resistant and insulin sensitive muscle. This was confirmed with real-time PCR. Our results suggest that insulin resistance is not reflected by changes in the gene expression profile in skeletal muscle.

• Toxicological Research
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• v.25 no.2
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• pp.59-69
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• 2009

Metabolomics which deals with the biological metabolite profile produced in the body and its relation to disease state is a relatively recent research area for drug discovery and biological sciences including toxicology and pharmacology. Metabolomics, based on analytical method and multivariate analysis, has been considered a promising technology because of its advantage over other toxicogenomic and toxicoproteomic approaches. The application of metabolomics includes the development of biomarkers associated with the pathogenesis of various diseases, alternative toxicity tests, high-throughput screening (HTS), and risk assessment, allowing the simultaneous acquisition of multiple biochemical parameters in biological samples. The metabolic profile of urine, in particular, often shows changes in response to exposure to xenobiotics or disease-induced stress, because of the biological system's attempt to maintain homeostasis. In this review, we focus on the most recent advances and applications of metabolomics in toxicological research.

• Magazine of the Korean Society of Agricultural Engineers
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• v.29 no.3
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• pp.153-162
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• 1987

A numerical procedure for the analysis of slender arch buckling problems for uniform dead weight is presented in this paper. Such loading changes in the arch profile. The problem is nonlinear. The numerical procedure is limited to an inextensible analysis and to elastic behavior. Based upon a numerical integration technique developed by Newmark for straight beams, a large deflection bending analysis is combined with small deflection buckling routines to formulate the numerical procedure. The numerical procedure is composed of a combination of the numerical integration and successive approximations procedure. The results obtained in this study are as follows : 1.The critical loads obtained in this study coincide with the results by Austin so that the algorithm developed in this study is verified. 2.The numerical results are converged with good precision when the half arch is divided into 10 segments in both Prime and Quadratic section. 3.The critical loads are decreased as the ratios of rise versus span are increased. 4.The critical loads are increased as the moments of inertia at the ends are increased. 5.The critical loads of Prime section are larger than that of Quadratic section under the same profile conditions.

• Korean Journal of Materials Research
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• v.13 no.5
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• pp.285-291
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• 2003

The nanosized silver and gold particles are prepared by ERC method in which metal vapors with high temperature is rapidly quenched by coolants such as liquid nitrogen or liquid argon. In order to monitor the crystal structural changes on the internal and the surface of the nanosized noble metal particles, lattice parameter, internal strain and Debye-Waller factor are investigated, and the calculation of X-ray diffraction scattering intensity is performed. The lattice parameters of silver and gold particles agree with those of bulk materials, and crystal internal strain of the metal particles is not changed by rapid cooling. The Debye-Waller factor of gold particles is increased with decreasing particle size because of the surface softening phenomenon of nanosized particles, but the crystal structural change on the surface of the particles is not detected from the comparison the calculated X-ray diffraction profile with the experimental profile on gold particles with the particle size of 4 nm.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.4
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• pp.629-636
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• 1987

An experiment is carried out to study the surface-tension driven flow characteristics in a cylindrical liquid column heated from above (which is the low gravity floating zone simulated on earth) with varing the aspect ratio and diameter of the liquid column. Hexadecane, octadecane, silicon oil(10cs), FC-40 and water are used as the test liquids. The free surface shape varies sinusoidally for Ma>M $a_{cr}$ and its frequency is found to be the same as that of temperature oscillation. It is verified that the surface temperature profile changes from linear to S-shaped profile for Ma>M $a_{cr}$ . The frequency of temperature oscillation decreases with increasing liquid volume, while its level increases. M $a_{cr}$ decreases with increasing aspect ratio, and also decreases with increasing Prandtl number in the range of 25

• The Journal of Internal Korean Medicine
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• v.34 no.4
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• pp.456-465
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• 2013

Objectives : A case of cervical dystonia improved after Korean medical treatments by using measurements of Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), and Cervical Dystonia Impact Profile (CDIP-58) to evaluate the changes of symptoms. Methods : Korean medical treatments for relieving symptoms of cervical dystonia including acupuncture, herb medication, cupping therapy, and physical therapy were performed. To evaluate the effect of the treatments, TWSTRS and CDIP-58 were used. Results : TWSTRS decreased from 55 to 24.5 and CDIP-58 also decreased from 79.3 to 36.2. Conclusions : This report suggests that Korean medical treatments can be effectively used for patients with cervical dystonia. Further clinical studies are needed to verify the findings.

• Korean Journal of Computational Design and Engineering
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• v.5 no.2
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• pp.175-183
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• 2000

Proposed in this paper is a model-bated AFA (automatic feedrate-adjustment) method for maintaining smooth cutting-loads (i.e., cutting-force) during 2D-profile milling. Before the cutting-force model was established, some assumptions were verified through a series of preliminary cutting experiments (The results found that the curving-force was independent of the cutting speed and the cutting action at the cutter bosom). From the data obtained during the main cutting experiments, a “chip-load/cutting-force model”representing the cutting-force as a function of the chip-load (i.e., effective cutting-depth) and a feedrate is proposed. Based on the model. an AFA scheme for maintaining smooth cutting-force by adjusting the feedrate (i.e., F-code) according to the changes in chip-load was proposed. To check the validity of the proposed AFA scheme. another set of cutting experiments was conducted by using feedrate-adjusted NC-data while monitoring the actual machining processes using an accelerometer. The experimental results showed that the proposed AFA-scheme was quite effective.