• 한국축산식품학회지
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• 제44권1호
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• pp.216-224
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• 2024

The reduction of nitric oxide (NO) bioavailability in the endothelium induces endothelial dysfunction, contributing to the development of hypertension. Although Lactobacillus consumption decreases blood pressure, intracellular signaling pathways related to hypertension have not been well elucidated. Thus, this study examined the effect of spray-dried Lactiplantibacillus plantarum K79 (LpK79) on NO production, intracellular signaling pathways, and inflammatory responses related to vascular function and hypertension. NO production was assessed in human umbilical vein endothelial cells (HUVECs) treated with LpK79. Endothelial NO synthase (eNOS) and intracellular signaling molecules were determined using Western blot analysis. LpK79 dose-dependently increased NO production and activated eNOS via the phosphoinositide 3-kinase/Akt signaling pathway HUVECs. Moreover, LpK79 mitigated the activation of crucial factors pivotal for vascular contraction in smooth muscle cells, such as phospholipase Cγ, myosin phosphatase target subunit 1, and Rho-associated kinase 2. When HUVECs were treated with LpL79 in the presence of Escherichia coli lipopolysaccharide (LPS), LpK79 effectively suppressed mRNA and protein expression of pro-inflammatory mediators induced by E. coli LPS. These results suggest that LpK79 provided a beneficial effect on the regulation of vascular endothelial function.

• Preventive Nutrition and Food Science
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• 제13권4호
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• pp.362-365
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• 2008

Agaricus bisporus, also known as white button mushroom, is one of the most popular mushrooms consumed in Korea. This mushroom contains high concentrations of flavanoids and exhibits antioxidant activity. In this study, we examined the effects of Agaricus bisporus ethanol extract (ABE) on lipopolysaccharide (LPS)-induced inflammation in RAW 264.7 cells. Nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) protein levels were assessed in cells treated with $100\;{\mu}M$ LPS in the presence or absence of ABE. 0.5 mg/mL of ABE suppressed NO production significantly. Moreover, ABE inhibited levels of iNOS protein. Taken together, these results suggest that ABE exerts anti-inflammatory activity in LPS-induced inflammation in RAW 264.7 cells.

• 산업공학
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• 제16권1호
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• pp.70-84
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• 2003

Recently, object-oriented techniques have been used more and more for developments of an information system. But, established object-oriented methodologies are hard to express a business process of various abstract degrees in the analysis level and independent components of the system. They have difficulties in developing a large-scale information system of manufacturing industry such as PDM and CIM. This paper proposes an information system development methodology that imports the object-oriented IDEF0 (OOIDEF0) function model in analysis level. This methodology is made up of requirements gathering, system analysis, system design, and implementation. In requirements gathering level, organization diagram and interview technique are used for input data of OOIDEF0 function model. The OOIDEF0 function model, the interface model and function descriptions are made out in analysis level. Information objects and implementation objects are designed on the basis of the OOIDEF0 function model in design level. The database is built and programming is accomplished in implementation level. In order to prove the consistency and efficiency of the proposed methodology, the PDM system for ship production is modeled and prototyped.

• 한국CDE학회논문집
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• 제16권6호
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• pp.397-406
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• 2011

Since tolerance allocation in a mobile phone camera manufacturing process greatly affects production cost and reliability of optical performance, a systematic design methodology for allocating optimal tolerances is required. In this study, we proposed the tolerance optimization procedure for determining tolerances that minimize production cost while satisfying the reliability constraints on important optical performance indices. We employed Latin hypercube sampling for evaluating the reliabilities of optical performance and a function-based sequential approximate optimization technique that can reduce computational burden and well handle numerical noise in the tolerance optimization process. Using the suggested tolerance optimization approach, the optimal production cost was decreased by 30.3 % compared to the initial cost while satisfying the two constraints on the reliabilities of optical performance.

• 농업과학연구
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• 제37권3호
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• pp.509-514
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• 2010

The purpose of this study is to analyze the technical efficiency and its determinants for Korean Apiculture farming by using from door to door and e-mail inquiry data. The analysis was implemented through the Cobb-Douglas stochastic frontier production function (SFPF) model including the technical inefficiency effect model for cross-sectional data. To measure the SFPF model, honey production was used for a dependent variable, and for input variables labor cost, preventive cost, material cost, feeding cost, depreciation cost were used. Farmer's age, farmer's career, farming scale, full-time or half-time firm and movement or fixed firm variables were used to measure the inefficiency effect model. The average technical efficiency on apiculture farming in Korea is estimated to be 0.8112. It means that there were technical inefficiency of about 18.88% in Korea apiculture farming. In this study there are some suggestions which could increase the technical efficiency of Korean apiculture farming.

• Journal of Information Display
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• 제5권4호
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• pp.23-26
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• 2004

A limitation of oxide cathode is the high current density, caused by low electrical conductivity of an emitter layer. This limitation can be overcome by increasing the conductivity, and uniform dispersion of Ni powder and pore agent could be achieved by using the screen-printing method. This new cathode has shown not only high current density reliability but also improved performance characteristics and as such given the name "Multi-Function cathode". It is expected to be a good replacement of the impregnated cathode.

• 한국태양에너지학회 논문집
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• 제28권5호
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• pp.1-7
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• 2008

Flashed steam system is one of the important geothermal power production methods. In this paper, optimum operations and performances of single and double flash systems are presented. It is shown that double flash system can produce about 26.5% more power than single flash system. Temperature of geothermal water($T_R$) is the most important parameter in the geothermal system. Optimum single and double flash temperatures and net power produced with these optimum conditions are expressed as a function of $T_R$ in this study. Thus net power output from geothermal resources can be estimated with the results of this work. Condenser Temperature($T_{con}$) is also important and the net power production can be shown as a function of ($T_R-T_{con}$. Volume flow rate per unit power is also to be considered as the condenser temperature decreases.

• 농업과학연구
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• 제31권2호
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• pp.135-148
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• 2004

Rice is not only main food but also key farm income source of Korean farmers. In spite of the above facts, rice productivity was decreased on account of drought in every 2 or 3 years interval owing to the vulnerability of irrigation facilities throughout Korea in the past decades. As an context of the first five year economic development plan, all weather farming programme including 4 big river basin comprehensive development projects and large and medium sized irrigation water development projects were carried out successfully. Therefore the area of irrigated paddy were increased from 58% in 1970 to 76.2% in 1999. In the past decades, the Government had invested heavy financial funds to develop irrigation water but as an factor share analysis, the contribution rates of irrigation water and investment for farmland base development project have not been identified yet in national agricultural economic level. It is very scarce to find out the papers concerned to macro-economic factor share analysis or contribution rates of water and investment cost to rice production value in Korea considering the production function of the quantity of irrigation water and investment cost as independent variables. Accordingly this paper covered and aimed at identifying (1) derivation of rice production function with the time serial data from 1965 to 1999 and the contribution rates of irrigation water and total investment cost for farmland base development project. The analytical model of the contribution rates was adapted the famous Cobb-Douglass production function. According to the model analysis, the contribution rate of irrigation water to rice production in Korea was shown 37.8% which was equivalent to 0.28 of the production elasticity of water. The contribution rate of farmland base development project cost was revealed 22% and direct production cost of rice was contributed 60% in the growth of rice production and farm mechanization costs contributed to 18% of it respectively. The two contribution rates comparing with the direct production cost were small but without irrigation water and farmland base development, application of high-pay off inputs and farm mechanization might be impossible. Considering the food security and to cope with the frequent drought, rice farming and investment for the irrigation water development should be continued even in WTO system.

• 서비스연구
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• 제6권1호
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• pp.83-95
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• 2016

본 논문은 한국은행 경제통계시스템에서 제공한 서비스업생산지수와 서비스업도소매지수를 가지고 상호간의 연관성을 분석하였다. 분석을 위한 통계분석 기간은 2000년 1월부터 2015년 9월까지 15년 9개월간의 월별자료 189개를 사용하였고, 분석도구로는 E-Views 6을 이용하여 VAR 모형을 통한 그랜저 인과관계분석(Granger Causality test)과 충격반응분석(Impulse Response Function) 및 분산분해(Variance Decomposition)를 실시하였다. 주요 분석결과는 다음과 같다. 첫째, 그랜저 인과관계 분석결과(Granger Causality test) 상승률과 변동성에 있어서 서비스업생산지수와 서비스업도소매지수 상호간에 예측력이 있음을 알 수 있었다. 둘째, 충격반응함수(Impulse Response Function)분석결과 서비스업생산지수와 서비스업도도소매지수에 사이에 충격이 존재하여 일정시차까지 영향을 미치다가 사라짐을 알 수 있었다. 이는 다른 산업뿐만 아니라 서비스업산업에 있어서도 생산량은 어느 정도 도소매업체의 판매량을 예측할 수 있다는 것으로 해석할 수 있다. 마지막으로 분산분해(Variance Decomposition) 분석결과 서비스업도소매지수는 일정시차동안 73.65%~65.59%의 서비스업생산지수에 의하여 영향을 받는 것으로 나타났다. 하지만 서비스업생산지수는 일정시차동안 0.97%~1.92%의 서비스업도소매지수에 영향을 받는 것으로 나타나 영향력이 미미함을 알 수 있었다. 본 연구는 다양한 지수를 대상으로한 상호간의 가격발견을 통한 상호연관성을 분석한 기존의 연구방법을 확장하여 서비스업생산지수와 서비스업도소매지수와의 가격발견 기능을 파악하는데 기여하였다고 사료된다. 이와 같은 연구결과는 물가지수를 관리하고 있는 정부에게 물가정책을 수립하는데 의미를 부여하고, 각종 지수를 관리하고 있는 한국은행 및 통계청에게 의미 있는 시사점을 제공할 것으로 판단된다. 본 연구에 대한 한계점으로는 물가지수를 이용한 선행연구가 많지 않아서 좀 더 체계적인 분석이 부족하다는 점과 구조변화 시점을 구분하여 분석하지 못했다는 점이다. 따라서 다양한 물가지수를 활용한 후속연구와 구조변화를 전후를 대상으로 한 추가연구가 필요하다고 사료된다.

• 한국습지학회지
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• 제20권2호
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• pp.190-200
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• 2018

본 연구는 공업용수 공급사업에 따른 경제적 가치를 확인하기 위하여 생산함수 접근법에 기반한 한계생산가치를 추정하였다. 이를 위해 Cobb-Douglas, Translog, Sector 더미변수를 포함한 Trasnslog 생산함수를 기준으로 11개 산업유형별로 구분된 4가지 자료세트(Case)를 이용하여 분석하였다. 분석결과, 전 산업 평균 한계생산가치는 각각 3,217~5,357원/ton, 2,994~4,569원/ton, 3,620~5,342원/ton로 나타났으며, 산업유형별 결과는 가구 및 기타제조 산업에서 가장 크게 추정되었고, 섬유 가죽산업에서 가장 낮은 한계생산가치를 보였다. 전체적으로 Cobb-Douglas 함수에 의한 결과가 높게 나타났으며, 자료세트에 따른 변동성 또한 Cobb-Douglas 함수에서 크게 나타났다. 생활용수에 비해 공업용수의 경제적 가치에 관한 연구는 그동안 미흡하였으나, 향후 활발한 연구를 통해 다학제간 합의가 필요할 것으로 판단된다.