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Practice of industrial strain improvement (제 1차 한.중 생명공학 심포지움)

  • Lei, Zhao-zu
    • The Microorganisms and Industry
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    • v.19 no.2
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    • pp.34-41
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    • 1993
  • Industrial strain improvement is concerned with developing or modifying microorganisms used in production of commercially important fermentation products. The aim is to reduce the production cost by improving productivity of a strain and manipulating specific characteristics such as the ability to utilize cheaper raw materials or resist bacteriophages. The traditional empirical approach to strain improvement is mutation combined with selection and breeding techniques. It is still used by us to improve the productivity of organisms in amino acids, organic acids and enzymes production. The breeding of high L-lysine-producing strain Au112 is one of the outstanding examples of this approach. It is a homoserine auxotroph with AEC, TA double metabolic analogue resistant markers. The yield reaches 100 g/l. Besides, the citric acid-producing organism Aspergillus niger, Co827, its productivity reaches the advanced level in the world, is also the result of a series mutations especially with $^60Co{\gamma}$-radiation. The thermostable .alpha.-amylase producing strain A 4041 is the third example. By combining physical and chemical mutations, the strain A 4041 becomes an asporogenous, catabolite derepressed mutant with rifamycin resistant and methionine, arginine auxotroph markers. The .alpha.-amylase activity reaches 200 units/ml. The fourth successful example of mutation in strain improvement is the glucoamylase-producing strain Aspergillus niger SP56, its enzyme activity is 20,000 units/ml, 4 times of that of the parental strain UV-11. Recently, recombinant DNA approach provides a worthwhile alternative strategy to industrial strain improvement. This technique had been used by us to increase the thermostable .alpha.-amylase production and on some genetic researches.

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A Study on the Characteristics of the Cultured Oyster Marketing in Sacheon Bay (사천만 양식 굴의 유통 특성 연구)

  • Bong-Yong Park;Jong-Ho Kang
    • The Journal of Fisheries Business Administration
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    • v.53 no.4
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    • pp.069-078
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    • 2022
  • This study studied the characteristics of cultured oyster marketing in Sacheon Bay. The results of this study are summarized as follows. First, the GULDAE aquaculture is a unique production method of Sacheon Bay. Second, oysters in Sacheon Bay were low in production, but the price was more than 70% higher than in other producing areas. Third, profit is 12.5% higher and rate of return was 179.8%. Fourth, there were more out-of-market sales than other than other producing areas, and it is a bidding method. Fifth, the marketing cost was higher than the longline hanging aquaculture; however, the advantage of price offseted this point. Although the Sacheon Bay Oyster aquaculture is small, it was confirmed that it was a producing area with high profitability and a unique marketing form from other regions. Although the Sacheon Bay Oyster culture is small, it has been confirmed that it is a producing area with high profitability and shows a unique distribution form.

FODDER PRODUCTION AT SAVAR DAIRY FARM: AN ECONOMIC ANALYSIS

  • Rahman, S.M.A.;Begum, J.;Alam, J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.9 no.4
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    • pp.411-420
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    • 1996
  • Asia Triple HIn this study an attempt was made to determine the cost of producing fodders at Savar Dairy Farm (SDF). For this purpose, all seasonal fodders, such as Maize, Jowar, Cowpea and Oat and all perennial fodders, such as Para and Napier were studied. The highest acreage of land was allocated to high-land Para (33.8%) and the lowest acreage (2.7%) was devoted to Cowpea. Jowar attained the highest yield (74.2 tons) per hectare and Maize attained the lowest yield (25.8 tons/h). The highest cost per hectare was attributed to Jowar (TK. 20944.18) while the lowest cost was attributed to low-land para (TK. 10349.86). The cost of production of fodder per kilogram was the highest (TK. 0.66) for Maize and the lowest for Oat (TK. 0.24). The cost of production of low-land Para was much lower than that of high land Para. The per kilogram cost of silage production was the highest (TK. 0.71) for Maize and the lowest (TK. 0.31) was for Napier. The gross return analysis further showed that the highest net margin and B:C ratio were observed for Napier followed by Low-land Para, Jowar, Oat, Cowpea, High-land Para and Maize. Therefore, those fodders whose B:C ratios and yield/ha were higher should be allocated more area of land to stimulate increased returns to SDF in the future is suggested.

Study on a Scheme of Investment Considering Customer Interruption Cost in Power Distribution System (정전비용을 고려한 배전계통 설비의 투자 계획 수립 방안연구)

  • Chu, Cheol-Min;Kim, Jae-Chul;Lee, Tae-Hee;Moon, Jong-Fil
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2006.05a
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    • pp.365-369
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    • 2006
  • It is concentrated on a methodology to establish a scheme of investment on power distribution systems of components. This paper provides a methodology to estimate the scheme as using a customer interruption cost regarding reliability indices in power distribution systems. The proposed method basically uses the failure rate depending on time for explaining the deterioration of a component. Therefore, the theory of the sensitivity is used for deciding the precedence of the investment to consider an effect of each component's failure rate on the system reliability. After Estimating the sensitivity on component investment cost making incremental reliability level is produced by component's investment cost accumulated according to the precedence of the sensitivity. After that, the failure rate corresponding with reliability level on the curve of investment cost is used as producing the curve of customer interruption cost. Two curves have the crossing point that is proposed to acceptable reliability level for customer and utility. In this paper, the acceptable reliability level for customer with the utility is assessed to analyze customer interruption cost and sensitivity of reliability indices. In conclusion the result of investment based on this method is shown to the reliability level with two cost.

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An Exploratory Study of Material Flow Cost Accounting: A Case of Coal-Fired Thermal Power Plants in Vietnam

  • NGUYEN, To Tam
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.5
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    • pp.475-486
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    • 2022
  • The purpose of this paper is to examine the use of material flow cost accounting (MFCA) in Vietnam's coal-fired thermal power plants. This study is based on the contingency and system theories to explain the application of management tools and analyze steps of input, output, and process in manufacturing. Costs in producing process-based MFCA include material cost, energy cost, system cost, and waste management cost. The exploratory case study methodology is used to describe and answer two questions, namely "How coal flow cost is recognized?" and "Why waste in material consumption can be harmful to the environment?". By analyzing the Quang Ninh and Pha Lai coal-fired thermal power plants that are the typical plants, this paper identifies the flow of primary material in these plants as a basis for determining losses for the business. The material flow of coal-fired thermal power plants provides the basis for the use of the MFCA. The manufacturing of electrical items in these plants is divided into four stages, each with its own set of losses. As a result, some phases in the application of MFCA are suggested, as well as some other elements required for MFCA application in coal-fired thermal power plants.

Strength Estimation of GGBF Slag Concrete by Warm Water Method (온수법에 의한 고로슬래그 미분말 혼합 콘크리트의 강도추정)

  • 문한영;최연왕;김용직
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.05a
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    • pp.313-318
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    • 2001
  • The cost of producing ready mixed concrete(remicon) has increased due to the rising cost of raw materials for concrete and transportation caused by the upturn of oil price. In contrast, its orders have also decreased due to the recession of the construction industry. In addition, the cost of delivery has decreased owing to the excessive competition among manufacturing companies, so manufacturing companies began mixing ground granulated blast-furnace slag or fly ash to lower the cost. However, there is no way to determine whether the strength of the concrete using the admixture is satisfied or dissatisfied with design strength at the early age. The purpose of this study is dedicated to early strength estimation of concrete mixed with an admixture, ground granulated blast-furnace slag.

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Wear Limit of Tool by the Shift and Failure of a Machining Process (절삭공정의 변이와 고장에 의한 가공공구의 마모한계)

  • 이도경
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.18 no.35
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    • pp.9-16
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    • 1995
  • The degeneration of tool in material removal processing machinery can be characterized by wear, deflection, chattering and any failure in tool or in the material In be processed. In the previous studies, first three of them are analyzed as a preventive maintenance strategy in quality control area. The last of them, any failure, is analyzed as a preventive maintenance strategy in reliability area. In this research, we propose a simple integrated mathematical model which minimizes the cost of machinery failures and producing defects. We determine the optimal wear limit of tool by considering the percent defects. cost, the preventive maintenance cost, and the corrective maintenance cost.

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Effect of Dietary Inclusion of Black Soldier Fly Larvae Hermetia illucens Meal on Growth Performance of Starry Flounder Platichthys stellatus and Feed Value (강도다리(Platichthys stellatus) 배합사료 내 곤충분 첨가에 따른 성장 및 사료가치 비교)

  • Seong-Mok Jeong;Nam-Lee Kim;Sang-Woo Hur;Seunghan Lee;Jinho Bae;Kang-Woong Kim
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.4
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    • pp.373-379
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    • 2023
  • The dietary inclusion of black soldier fly larvae meal Hermetia illucens (BSL) for starry flounder Platichthys stellatus was examined in a four-month trial at a Pohang fish farm. Two diets were prepared: a fish meal-based commercial diet (CD) and an experimental diet containing 7% BSL in the CD (BCD). Fish (average weight, 125.2 g) were reared in a square concrete tank (7×7 m) in triplicates. Feed efficiency was significantly higher in fish fed BCD compared to that of the fish fed CD. The DHA/EPA ratio in dorsal muscle was not significantly affected by the fatty acid composition of the experimental diets. Based on the growth performance, the feed cost for producing 1 kg of starry flounder was 1,797 won for CD and 1,814 won for BCD. With government subsidies the feed cost for producing 1 kg of starry flounder was 1,481 won for CD and 1,309 won for BCD. The results indicate that BSL can be included at 7% without adverse effects on growth performance, fillet composition, or feed cost. However, further research is needed to determine the optimum percentage of BSL as a replacement of FM in starry flounder diets.

Production of Endoglucanase, Beta-glucosidase and Xylanase by Bacillus licheniformis Grown on Minimal Nutrient Medium Containing Agriculture Residues

  • Seo, J.;Park, T.S.;Kim, J.N.;Ha, Jong K.;Seo, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.7
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    • pp.946-950
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    • 2014
  • Bacillus licheniformis was grown in minimal nutrient medium containing 1% (w/v) of distillers dried grain with soluble (DDGS), palm kernel meal (PKM), wheat bran (WB) or copra meal (CM), and the enzyme activity of endoglucanase, ${\beta}$-glucosidase, xylanase and reducing sugars was measured to investigate a possibility of using cost-effective agricultural residues in producing cellulolytic and hemicellulolytic enzymes. The CM gave the highest endoglucanase activity of 0.68 units/mL among added substrates at 48 h. CM yielded the highest titres of 0.58 units/ml of ${\beta}$-glucosidase, compared to 0.33, 0.23, and 0.16 units/mL by PKM, WB, and DDGS, respectively, at 72 h. Xylanase production was the highest (0.34 units/mL) when CM was added. The supernatant from fermentation of CM had the highest reducing sugars than other additional substrates at all intervals (0.10, 0.12, 0.10, and 0.11 mg/mL respectively). It is concluded that Bacillus licheniformis is capable of producing multiple cellulo- and hemicellololytic enzymes for bioethanol production using cost-effective agricultural residues, especially CM, as a sole nutrient source.

Speaker Adapted Real-time Dialogue Speech Recognition Considering Korean Vocal Sound System (한국어 음운체계를 고려한 화자적응 실시간 단모음인식에 관한 연구)

  • Hwang, Seon-Min;Yun, Han-Kyung;Song, Bok-Hee
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.6 no.4
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    • pp.201-207
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    • 2013
  • Voice Recognition technique has been developed and it has been actively applied to various information devices such as smart phones and car navigation system. But the basic research technique related the speech recognition is based on research results in English. Since the lip sync producing generally requires tedious hand work of animators and it serious affects the animation producing cost and development period to get a high quality lip animation. In this research, a real time processed automatic lip sync algorithm for virtual characters in digital contents is studied by considering Korean vocal sound system. This suggested algorithm contributes to produce a natural lip animation with the lower producing cost and the shorter development period.