• Title/Summary/Keyword: processed agent

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The Synthesis of Diphenyl ethanolamidophosphate (DPEAP) and the Flame Retardancy of Cotton Fabric (Diphenyl ethanolamidophosphate의 합성과 면섬유에 대한 방염성)

  • Huh, Man Woo;Yoon, Jong Ho;Cho, Yong Suk;Kim, Young Suk;Lim, Hak Sang
    • Textile Coloration and Finishing
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    • v.8 no.2
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    • pp.25-34
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    • 1996
  • Diphenyl ethanolamidophosphate(DPEAD) was synthesized for the purpose of developing a new flame retardant for cotton fabric. As the intermediate material was used diphenyl chlorophosphate(DPCP) and it was synthesized by using phosphorus oxychloride and phenol as the starting materials. The final product DPEAP was obtained by the reaction of DPCP and ethanolamine. The flame retardancy of cotton fabrics treated by DPEAP through pad-dry-cure(PDC) process was examined at various conditions. The physical property change of the DPEAP treated cotton fabrics were investigated by examining the drape stiffness, the wrinkle recovery, and the tensile strength. The results are summarized as follows: (1) DPEAP has shown excellent flame retardancy on cotton fabrics in comparison to other flame retardants for cotton fabrics available commercially. (2) The optimal condition for PDC process found was that the curing temperature was 16$0^{\circ}C$, the DPEAP concentration was 10%, the catalyst $({NH_{4})_{2}HPO_{4}$ concentration was 7.0%, and the fixing agent hexamethylol melamine (HMM)/DPEAP weight ratio was 1/8. (3) The wrinkle recovery of the processed fabrics increased with increasing DPEAP concentration. (4) The drape stiffness of the cotton fabrics treated by DPEAP have shown essentially no change until increasing DPEAP concentration to 15 %, however DPEAP concentration exceeds 20% the drape stiffness increased drastically with increasing DPEAP concentration. When DPEAP concentration is kept constant the drape stiffness increased with increasing $({NH_{4})_{2}HPO_{4}$ concentration and HMM/DPEAP weight ratio. (5) The tensile strength of the processed fabrics was lower than that of untreated fabrics, but the tensile strength retention increased with increasing DPEAP concentration.

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Preparation and Characterization of PEG-impregnated Aloe Gel through DIS Processing of Aloe vera Leaf Slice (DIS 공정에 의한 Polyethylene Glycol 함침 알로에 베라 겔의 제조 및 특성화)

  • Kwon, Hye Mi;Hur, Won;Lee, Shin Young
    • KSBB Journal
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    • v.28 no.6
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    • pp.356-365
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    • 2013
  • The novel Aloe gels were prepared with dewatering and impregnation by soaking (DIS) processing of Aloe vera leaf slice at four different temperatures (25, 35, 45 and $55^{\circ}C$), using dehydration solution of 40% (w/v) polyethylene glycol (PEG4000). The PEG-impregnation to Aloe vera leaf slice during DIS was observed depending on immersion temperature, and the PEG-impregnated Aloe vera gel (PEG-i-AVG) obtained was characterized using $^1H$ NMR, FT-IR, GPC, XRD and TGA. The PEG-i-AVG had the higher levels of Aloe bioactives (glucomannan and O-acetyl contents) and better quality indices by $^1H$ NMR and FT-IR spectroscopy than those of native Aloe gel. Also, the obtained Aloe gel maintained the bimodal patterns in higher molecular weight region by GPC indicating no degradation of polysaccharide from native Aloe gel. The result observed by SEM confirmed a surface modification by forming the porous structure, and TGA result exhibited better thermal stability than that of native Aloe gel. XRD result revealed that the crystalline structure in Aloe gel was led by incorporation of PEG. Significant decrease of %insolubility and high enhancement of water solubility index were observed, respectively, and highly ordered conformation such as a helix structure was also indicated by Congo red reaction. We concluded that the modification effect for enhancing function of native Aloe gel was successfully obtained by DIS process using PEG as a dehydrating agent. These results suggested that this DIS process had a high potential for developing a new minimally processed product from Aloe vera leaf.

Effects of Antidiabetic Agent, Aloe QDM complex, on Intracellular Glucose Uptake (항당뇨 물질 Aloe QDM complex의 세포내 포도당 흡수촉진 효능)

  • Im, Sun-A;Kim, Ki-Hyang;Shin, Eunju;Do, Seon-Gil;Jo, Tae Hyung;Park, Young-In;Lee, Chong-Kil
    • Korean Journal of Pharmacognosy
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    • v.44 no.1
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    • pp.75-82
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    • 2013
  • Previous studies have shown that Aloe QDM complex, which is consisted of chromium (Cr), aloesin (ALS) and processed Aloe vera gel (PAG), exert antidiabetic activity in a high fat diet-induced mouse model of type 2 diabetes. In this study we examined the mechanism of the antidiabetic activity of the Aloe QDM complex. Rat myoblast cell line L6 cells were cultured in the presence of Cr, ALS, and PAG alone and in combinations, and then the capability of the cells to uptake glucose was examined using radiolabeled glucose. All of the 3 agents, Cr, ALS and PAG, exerted glucose uptake-enhancing activity in L6 cells. The most potent capability to uptake glucose was observed when L6 cells were cultured with the Aloe QDM complex. The activity of the Aloe QDM complex to enhance glucose uptake was prominent in conditions where existing insulin concentrations are low. We also examined the effects of the Aloe QDM complex on the plasma membrane expression of GLUT4 in L6 cells. The Aloe QDM complex increased the content of GLUT4 in the plasma membrane, while decreasing the content of GLUT4 in the light microsome. Taken together, these results show that the antidiabetic activity of the Aloe QDM complex is at least in part due to the stimulation of glucose uptake into the muscle cells, and this activity of the Aloe QDM complex is mediated through the enhancement of the translocation of GLUT4 into the plasma membrane.

Pectinase-Processed Ginseng Radix (GINST) Ameliorates Hyperglycemia and Hyperlipidemia in High Fat Diet-Fed ICR Mice

  • Yuan, Hai-Dan;Kim, Jung-Tae;Chung, Sung-Hyun
    • Biomolecules & Therapeutics
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    • v.20 no.2
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    • pp.220-225
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    • 2012
  • To develop a ginseng product possessing an efficacy for diabetes, ginseng radix ethanol extract was treated with pectinase and obtained the GINST. In the present study, we evaluate the beneficial effect of GINST on high fat diet (HFD)-induced hyperglycemia and hyperlipidemia and action mechanism(s) in ICR mice. The mice were randomly divided into five groups: regular diet group (RD), high fat diet group (HFD), HFD plus GINST at 75 mg/kg (GINST75), 150 mg/kg (GINST150), and 300 mg/kg (GINST300). Oral glucose tolerance test reveals that GINST improves the glucose tolerance after glucose challenge. Fasting plasma glucose and insulin levels were decreased by 4.3% and 4.2% in GINST75, 10.9% and 20.0% in GINST150, and 19.6% and 20.9% in GINST300 compared to those in HFD control group. Insulin resistance indices were also markedly decreased by 8.2% in GINST75, 28.7% in GINST150, and 36.4% in GINST300, compared to the HFD control group. Plasma triglyceride, total cholesterol and non-esterified fatty acid levels in the GINST300 group were decreased by 13.5%, 22.7% and 24.1%, respectively, compared to those in HFD control group. Enlarged adipocytes of HFD control group were markedly decreased in GINST-treated groups, and shrunken islets of HFD control mice were brought back to near normal shape in GINST300 group. Furthermore, GINST enhanced phosphorylation of AMP-activated protein kinase (AMPK) and glucose transporter 4 (GLUT4). In summary, GINST prevents HFD-induced hyperglycemia and hyperlipidemia through reducing insulin resistance via activating AMPK-GLUT4 pathways, and could be a potential therapeutic agent for type 2 diabetes.

Protective Effect of Processed Panax ginseng, Sun Ginseng on UVB-irradiated Human Skin Keratinocyte and Human Dermal Fibroblast

  • Lee, Hye-Jin;Lee, Joo-Yeop;Song, Kyu-Choon;Kim, Jin-Hee;Park, Jeong-Hill;Chun, Kwang-Hoon;Hwang, Gwi-Seo
    • Journal of Ginseng Research
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    • v.36 no.1
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    • pp.68-77
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    • 2012
  • In this study, we investigated the protective effects of processed Panax ginseng, sun ginseng (SG) against the UVB-irradiation on epidermal keratinocytes and dermal fibroblasts. Pretreatment of SG in HaCaT keratinocytes and human dermal fibroblasts reduced UVB-induced cell damage as seen by reduced lactate dehydrogenase release. We also found that SG restored the UVB-induced decrease in anti-apoptotic gene expression (bcl-2 and bcl-xL) in these cells, indicating that SG has an anti-apoptotic effect and thus can protect cells from cell death caused by strong UVB radiation. In addition, SG inhibited the excessive expression of c-jun and c-fos gene by the UVB in HeCaT cells and human dermal fibroblasts. We also demonstrated that SG may exert an anti-inflammatory activity by reducing the nitric oxide production and inducible nitric oxide synthase mRNA synthesis in HaCaT keratinocytes and human dermal fibroblasts. This was further supported by its inhibitory effects on the elevated cyclooxygenase-2 and tumor necrosis factor-${\alpha}$ transcription which was induced by UVB-irradiation in HaCaT cells. In addition, SG may have anti-aging property in terms of induction of procollagen gene expression and inhibition of the matrix metalloprotease-1 gene expression caused by UVB-exposure. These findings suggest that SG can be a potential agent that may protect against the dermal cell damage caused by UVB.

A5E promotes Cell growth Arrest and Apoptosis in Non Small Cell Lung Cancer

  • Bak, Ye Sol;Ham, Sun Young;O, Baatartsogt;Jung, Seung Hyun;Choi, Kang Duk;Han, Tae Young;Han, Il Young;Yoon, Do-Young
    • Journal of Applied Biological Chemistry
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    • v.57 no.2
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    • pp.113-122
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    • 2014
  • A5E is complex of several medicinal herb ethanol extracts. The aim of this study is investigating the anticancer effect for non-small cell lung cancer. The antitumor effects of A5E on NCI-H460 were examined by regulation of cell proliferation, apoptosis, cell cycle arrest, mitochondrial membrane potential (${\Delta}{\Psi}_m$), and apoptosis-related protein. Cell proliferation was measured by MTS assay. Apoptosis induced by A5E was confirmed by Annexin V-fluorescein isothiocyanate (FITC)/Propidium Iodide (PI) staining, and cell cycle arrest was measured by PI staining. NF-${\kappa}B$ translocation was detected by immunofluorescence and MMP (${\Delta}{\Psi}_m$) was measured by JC-1 staining. The expression of extrinsic pathway molecules such as FasL and FADD were elevated, and procaspase-8 was processed by A5E. In addition, intrinsic pathway related molecules were altered. The Bcl-2 and Bcl-xl levels decreased, Bax increased, and cytochrome C was released. In addition, the mitochondrial membrane potential collapsed, and caspase-3 and poly-(ADP-ribose) polymerase were processed by A5E. Moreover, A5E affected the cellular survival pathway involving phosphatidylinositol 3-kinase (PI3K)/Akt and NF-${\kappa}B$. PI3K and Akt were downregulated, also NF-${\kappa}B$ expression was decreased, and nuclear translocalization was inhibited by A5E. These results suggested that A5E delays proliferation, inhibit cell cycle progression and induce apoptosis in human lung cancer cell. We conclude that A5E is a potential anticancer agent for human lung carcinoma.

Study on the Defect Mechanism of Immersion Gold Layer (Immersion gold층의 결함 메카니즘 연구)

  • Lee, Dong-Jun;Choi, Jin-Won;Cho, Seung-Hyun
    • Journal of the Microelectronics and Packaging Society
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    • v.15 no.3
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    • pp.35-40
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    • 2008
  • Investigation on immersion gold layers was carried out using TEM analysis for the purpose of understanding the defect of immersion gold layer. The immersion gold layers prepared with three different types of baths were observed. The results showed that the defect structure of immersion gold layer is strongly dependent on the types of gold baths. Spherical defects of average 10 nm size were located along the grain boundaries for the specimen formed at KAu$(CN)_2$ bath containing no reducing agent. In the case of the specimen processed at KAu$(CN)_2$ bath containing a reducing agent, the spherical defects of 5-10 nm size were distributed randomly in grains as well as at grain boundaries. However, such defects disappeared almost completely when $Na_{3}Au(SO_3)_2$ bath was used to fabricate an immersion gold.

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Screening of Antibrowning Agents for Minimally Processed Vegetables (최소가공채소류에 적합한 갈변방지제의 선발)

  • Park, Woo-Po;Cho, Sung-Hwan;Lee, Dong-Sun
    • Korean Journal of Food Science and Technology
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    • v.30 no.2
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    • pp.278-282
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    • 1998
  • Peeled garlic, soybean sprouts, cut onion and cut green pepper were treated by dipping in solutions of different antibrowning agents, and then stored at $10^{\circ}C$. Surface color and polyphenol oxidase activity of produce were measured through the storage. Tested antibrowning agents include ascorbic acid, citric acid and allyl isothiocyanate. The commodities showed different responses to the antibrowning agent solutions; 1% citric acid for peeled garlic, 1% ascorbic acid for soybean sprouts, 2% citric acid for cut onion, and 1% ascorbic acid for cut green pepper showed better retardation in browning than the other treatments for respective product. For peeled garlic, surface browning was concomitant with increase in polyphenol oxidase activity during storage. On the other hand, there was no positive correlation between surface browning and polyphenol oxidase activity for the other stored products.

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Design and Implementation of Mobile Contents to provide Marine Leisure Information (해양레저정보를 제공하기 위한 모바일 콘텐츠의 설계 및 구현)

  • Jeong, Seong-Hoon
    • Journal of Advanced Navigation Technology
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    • v.13 no.1
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    • pp.11-18
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    • 2009
  • As a marine leisure industry has being developed and demands for leisure culture have rapidly increased, the needs for services offering marine safety and related information are growing. Accordingly, in the study I developed the contents providing server to support this with ENC agent who presents geographical information of digitalized Electronic Nautical Chart satisfying with the standard(S-57) by International Hydrographic Organization and a web searching agent who builds a database by collecting marine-related information in order to provide a variety of realtime information such as weather, fishing and news. In addition, I designed and embodied network based mobile contents which can be presented on a WIPI(Wireless Internet Platform for Interoperability) based portable handset by receiving an ENC and other processed information from server. With the results produced by such experiments, I measured a compressibility corresponding to a image compression format of electronic nautical chart transmitted and analyzed the correlation between increase in packets of requested information and the cost.

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A Study on the Omni-Channel Contact Center Agent Staffing Optimization Using Simulation (시뮬레이션을 활용한 옴니채널 컨택센터의 상담사 배치 최적화 연구)

  • Ryu, Ki-Dong;Jang, Seong-Yong;Kim, Woo-Je
    • Journal of the Korea Society for Simulation
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    • v.27 no.2
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    • pp.91-100
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    • 2018
  • Recently, the traditional call center, which has an important role as the customer's primary contact point, has been transformed into the omni-channel contact center which supports an additional variety of access channels in addition to phone calls in order to improve customer accessibility and convenience. The omni-channel contact center has agents on each channel which are vital in determining the response rate and waiting time for the customer. In traditional call centers, agents can be assigned to a call based on the characteristics of the call, however in omni-channel contact centers, the characteristics of issues vary and come in through multiple channels, each with their own characteristics, making it difficult to assign the appropriate agent for the issue. Customers must also be processed at the same time, adding an additional layer of complexity to the issue. This paper analyzes and simulates an omni-channel contact center that accommodates email, chat, voice calls and video consultation, and investigates how to optimize the allocation of agents.