• Title/Summary/Keyword: principal point

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A Review of Korean Medicine Treatment for Postherpetic Neuralgia

  • Kim, Min Ju;Cha, Hyun Ji;Lee, Young Rok;Kim, Beom Seok;Sung, Ki Jung;Choi, Hyeon Kyu;Lee, Ye Ji;Jeon, Ju Hyun;Kim, Young Il
    • Journal of Acupuncture Research
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    • v.38 no.4
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    • pp.245-256
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    • 2021
  • The purpose of this study was to analyze the Korean medicine treatment methods for Postherpetic Neuralgia (PHN) in Korea. There were 5 online databases searched (OASIS, NDSL, RISS, KISS and KMBASE) for studies which were related to PHN. A total of 12 studies were selected. Various treatments such as acupuncture, herbal medicine, and moxibustion were reported treatments for PHN, some of which included Western medicine and Korean medicine treatment. Korean herbal medicine was the most frequently used treatment method, followed by manual acupuncture. Sipjeondaebotanggami was the most frequently used prescription. Poria Sclerotium was the most frequently used principal herb, followed by Angelicae Gigantis Radix, Zingiberis Rhizoma, and Ginseng Radix. GB44, LI4, LR3 were the common acupoints used for the treatment of PHN. CV12 was the most frequently used moxibustion point, and gabapentin was the most frequently used concomitant Western drug. Additional research on Korean medicine treatment of PHN is expected in the future.

Factors affecting the Length of Stay in Patients with Total Knee Arthroplasty (슬관절 전치환술 환자의 재원일수에 영향을 주는 요인)

  • Lee, Hye-Seung;Kim, Hwan-Hui
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.6
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    • pp.201-208
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    • 2020
  • The purpose of this study was to analyze the claim data of Health Insurance Review & Assessment Service to determine what factors affected the length of stay in patients aged 65 and older and undergoing total knee arthroplasty due to the principal diagnosis of gonarthrosis by the type of medical institutions. As a result of making an analysis, gender, age, medical security type, severity, residential area and the number of sickbeds were identified as the factors that influenced the length of stay in each type of medical institutions. At this point in time when an increase in the elderly population triggered by population aging and another subsequent increase in medical expenses put a heavy strain on household and national economy, it's necessary to consider how to shorten the length of stay and how to ensure the efficient management of sickbeds based on the findings of this study. In addition, this study is of significance in that it could be used as basic data on quality life-care for elderly patients by the introduction of a systematic management system geared toward lessening patient burden for medical expenses.

Metabolomic profiling of postmortem aged muscle in Japanese Brown beef cattle revealed an interbreed difference from Japanese Black beef

  • Susumu Muroya;Riko Nomura;Hirotaka Nagai;Koichi Ojima;Kazutsugu Matsukawa
    • Animal Bioscience
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    • v.36 no.3
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    • pp.506-520
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    • 2023
  • Objective: Japanese Brown (JBR) cattle, especially the Kochi (Tosa) pedigree (JBRT), is a local breed of moderately marbled beef. Despite the increasing demand, the interbreed differences in muscle metabolites from the highly marbled Japanese Black (JBL) beef remain poorly understood. We aimed to determine flavor-related metabolites and postmortem metabolisms characteristic to JBRT beef in comparison with JBL beef. Methods: Lean portions of the longissimus thoracis (loin) muscle from four JBRT cattle were collected at 0, 1, and 14 d postmortem. The muscle metabolomic profiles were analyzed using capillary electrophoresis time-of-flight mass spectrometry. The difference in post-mortem metabolisms and aged muscle metabolites were analyzed by statistical and bioinformatic analyses between JBRT (n = 12) and JBL cattle (n = 6). Results: A total of 240 metabolite annotations were obtained from the detected signals of the JBRT muscle samples. Principal component analysis separated the beef samples into three different aging point groups. According to metabolite set enrichment analysis, post-mortem metabolic changes were associated with the metabolism of pyrimidine, nicotinate and nicotinamide, purine, pyruvate, thiamine, amino sugar, and fatty acid; citric acid cycle; and pentose phosphate pathway as well as various amino acids and mitochondrial fatty acid metabolism. The aged JBRT beef showed higher ultimate pH and lower lactate content than aged JBL beef, suggesting the lower glycolytic activity in postmortem JBRT muscle. JBRT beef was distinguished from JBL beef by significantly different compounds, including choline, amino acids, uridine monophosphate, inosine 5'-monophosphate, fructose 1,6-diphosphate, and betaine, suggesting interbreed differences in the accumulation of nucleotide monophosphate, glutathione metabolism, and phospholipid metabolism. Conclusion: Glycolysis, purine metabolism, fatty acid catabolism, and protein degradation were the most common pathways in beef during postmortem aging. The differentially expressed metabolites and the relevant metabolisms in JBRT beef may contribute to the development of a characteristic flavor.

A Study on Determining Trade Terms for Logistics Efficiency in the Era of Logistics 4.0: Moderated Mediating Effect of Added Value of Traded Goods

  • Chang-Bong Kim;Kyeong-Wook Jeong;Hwa-Jung Hyun
    • Journal of Korea Trade
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    • v.27 no.4
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    • pp.1-18
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    • 2023
  • Purpose - The purpose of this paper is to study how flexibility and mutuality in determining trade terms impact logistics efficiency in the context of relational theory. Additionally, the effect of relational contracts on logistical efficiency relative to the value of the goods being traded is investigated. Design/methodology - According to the relational contract theory, we developed 17 factors utilizing a 7-point Likert scale to measure variables related to flexibility, mutuality, logistics efficiency, and the added value of goods. The survey occurred over four months, and was distributed directly, and via email, phone, and online Google surveys. A total of 403 surveys were collected out of 1,800 distributed, and 380 were analyzed. The principal respondents were import/export companies and members of the Korea International Trade Association and the Korea Small and Medium Business Export-Import Association. The collected data were analyzed using frequency analysis, exploratory factor analysis, and correlation analysis using SPSS ver. 26.0 statistical software, and hypothesis test results were derived using Process Macro ver. 3.5. Findings - This study provides evidence that negotiation flexibility for trade terms affects the efficiency of the logistics process, and the mutuality of such arrangements is shown to be associated with the flexibility and efficiency of logistics processes. Additionally, it has been established that companies whose trade goods possess a low degree of added value may experience increased efficiency in logistics operations if they agree to trade terms that are both flexible and mutually beneficial with their counterparts. Originality/value - This study suggests that in an environment of rapidly shifting global logistics and unpredictable related costs, trade companies may be able to improve logistics efficiency by establishing flexible, mutually beneficial trade terms when entering into contracts. Furthermore, it is suggested that companies dealing in low-value-added products may improve the logistical performance of approaching trade from a perspective of relational contracts.

A Study on Guarantor's Wrongful Dishonor and Main Issues under Counter Guarantee (구상보증거래에서 보증은행의 부당한 지급거절과 주요 쟁점에 관한 연구)

  • Chae, Jin-Ik
    • Korea Trade Review
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    • v.43 no.6
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    • pp.25-50
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    • 2018
  • It is an undeniable fact that the counter-guarantees are always exposed to wrongful or fraudulent demands for payment due to its institutional hallmarks and simplicity. Generally counter-guarantees are payable by presenting a written statement indicating that the local guarantor was in receipt of the beneficiary's statement that the principal was in breach of the underlying contract without any proof of any default. No proof of actual payment of guarantee is required. These matters may lead to numerous disputes or conflicts between the parties concerned. These problems raise may legal issues such as a guarantor(or a counter-guarantor)'s dishonor, the wrongful or fraudulent demands for payment, and the fraudulent conspiracy or the acquiescence of the local guarantor in the course of the procedural demand for payment. On the other hand, the guarantor's dishonor or an injunction are sometimes misused as dispute resolution method between parties involved. Therefore, this research analyzed the guarantor's wrongful dishonor and related issues such as an injunction, fraud exception, and others under the counter-guarantee regime focusing on the relevant cases. This paper also suggested practical implications and countermeasures from a business point of view.

The impact of different shapes of aggregate and crumb rubber on the deformation properties of asphalt concrete

  • Felix N. Okonta;Koketso Tshukutsoane;Babak Karimi
    • Geomechanics and Engineering
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    • v.36 no.1
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    • pp.39-50
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    • 2024
  • Bitumen and high-quality subangular aggregates, the two principal materials used for asphalt concrete construction, are finite and expensive materials. The general availability of crumb rubber and naturally occurring aggregates of different shapes, especially flat and elongated shapes, indicates that they are feasible alternative materials for expanding the volume of bitumen and utilizing a wider range of aggregate shapes for the development of asphalt concrete, with an associated environmental benefit. The study investigated the effect of adding up to 15% crumb rubber and aggregates sorted into different groups, i.e., rounded, elongated, flat, and their combinations, on the rheological and mechanical properties and durability of 50/70 of hot-mix asphalt pavement. The addition of crumb rubber decreased ductility and penetration but increased the softening point. For a 5.5% bitumen content, asphalt concrete briquettes consisting of 7% crumb rubber and three types of aggregate shapes, i.e., 100% rounded, a mix of 75% rounded and 25% elongated, and a mix of 75% rounded, 15% elongated and 10% flat, were associated with high Marshall stability and indirect tensile strength as well as low lateral deformation due to their high solidity and moderate angularity ratio. Also, the addition of 7% crumb rubber resulted in a significant improvement in the tensile strength ratio and rebound strain of briquettes consisting of 75% rounded and 25% elongated aggregates and those with 75% rounded, 15% elongated and 10% flat aggregates. In relation to the parameters investigated, the three groups of briquettes met some of the local (South Africa) requirements for the surface course and base course of low traffic volume roads.

Statistical Analysis of Water Flow and Water Quality Data in the Imjin River Basin for Total Pollutant Load Management (임진강 유역 오염물질 총량관리를 위한 유량-수질 자료의 통계분석)

  • Cho, Yong-Chul;Choi, Hyeon-Mi;Lee, Young Joon;Ryu, Ingu;Lee, Myung-Gu;Gu, Donghoi;Choi, Kyungwan;Yu, Soonju
    • Journal of Environmental Impact Assessment
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    • v.27 no.4
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    • pp.353-366
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    • 2018
  • The purpose of this study was assessment the quality of water by using the statistical analysis technique of the Water flow and water quality from January 2012 to December 2016 at the unit basin for total pollutant load management system (TPLMS) in the Imjin River. Water flow and water quality were monitored at an average of 8 day intervals, 11 parameters were used for correlation analysis, principal component analysis (PCA), factor analysis (FA), and cluster analysis (CA). The Hierarchical CA was classified into three according to the change of space, such as natural rivers, urban rivers, point with large influence of point pollution source, it was found that the type of contamination source the similarity of water quality affected the classification of cluster. Using one-way analysis of variance (ANOVA) and post-hoc Analysis, there were statistically significant differences between mean values among the clusters. Correlation analysis showed the correlation coefficient between $COD_{Mn}$ and TOC was 0.951 (p<0.01) and the correlation was statistically significantly higher. According to the result PCA and FA, 3 principal components can explaining 72% of the total variations in water quality characteristics and main factor was EC, $BOD_5$, $COD_{Mn}$, TN, TP and TOC indirect indicators of organic matter and nutrients were influenced. This study presented the regression equation obtained by applying the factor scores to the multiple linear regression analysis and concluded that the management Indirect indicators of organic matter and nutrients is important for water quality management in the Imjin River basin.

Extraction of Landmarks Using Building Attribute Data for Pedestrian Navigation Service (보행자 내비게이션 서비스를 위한 건물 속성정보를 이용한 랜드마크 추출)

  • Kim, Jinhyeong;Kim, Jiyoung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.37 no.1
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    • pp.203-215
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    • 2017
  • Recently, interest in Pedestrian Navigation Service (PNS) is being increased due to the diffusion of smart phone and the improvement of location determination technology and it is efficient to use landmarks in route guidance for pedestrians due to the characteristics of pedestrians' movement and success rate of path finding. Accordingly, researches on extracting landmarks have been progressed. However, preceding researches have a limit that they only considered the difference between buildings and did not consider visual attention of maps in display of PNS. This study improves this problem by defining building attributes as local variable and global variable. Local variables reflect the saliency of buildings by representing the difference between buildings and global variables reflects the visual attention by representing the inherent characteristics of buildings. Also, this study considers the connectivity of network and solves the overlapping problem of landmark candidate groups by network voronoi diagram. To extract landmarks, we defined building attribute data based on preceding researches. Next, we selected a choice point for pedestrians in pedestrian network data, and determined landmark candidate groups at each choice point. Building attribute data were calculated in the extracted landmark candidate groups and finally landmarks were extracted by principal component analysis. We applied the proposed method to a part of Gwanak-gu, Seoul and this study evaluated the extracted landmarks by making a comparison with labels and landmarks used by portal sites such as the NAVER and the DAUM. In conclusion, 132 landmarks (60.3%) among 219 landmarks of the NAVER and the DAUM were extracted by the proposed method and we confirmed that 228 landmarks which there are not labels or landmarks in the NAVER and the DAUM were helpful to determine a change of direction in path finding of local level.

Development of Dose Planning System for Brachytherapy with High Dose Rate Using Ir-192 Source (고선량률 강내조사선원을 이용한 근접조사선량계획전산화 개발)

  • Choi Tae Jin;Yei Ji Won;Kim Jin Hee;Kim OK;Lee Ho Joon;Han Hyun Soo
    • Radiation Oncology Journal
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    • v.20 no.3
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    • pp.283-293
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    • 2002
  • Purpose : A PC based brachytherapy planning system was developed to display dose distributions on simulation images by 2D isodose curve including the dose profiles, dose-volume histogram and 30 dose distributions. Materials and Methods : Brachytherapy dose planning software was developed especially for the Ir-192 source, which had been developed by KAERI as a substitute for the Co-60 source. The dose computation was achieved by searching for a pre-computed dose matrix which was tabulated as a function of radial and axial distance from a source. In the computation process, the effects of the tissue scattering correction factor and anisotropic dose distributions were included. The computed dose distributions were displayed in 2D film image including the profile dose, 3D isodose curves with wire frame forms and dosevolume histogram. Results : The brachytherapy dose plan was initiated by obtaining source positions on the principal plane of the source axis. The dose distributions in tissue were computed on a $200\times200\;(mm^2)$ plane on which the source axis was located at the center of the plane. The point doses along the longitudinal axis of the source were $4.5\~9.0\%$ smaller than those on the radial axis of the plane, due to the anisotropy created by the cylindrical shape of the source. When compared to manual calculation, the point doses showed $1\~5\%$ discrepancies from the benchmarking plan. The 2D dose distributions of different planes were matched to the same administered isodose level in order to analyze the shape of the optimized dose level. The accumulated dose-volume histogram, displayed as a function of the percentage volume of administered minimum dose level, was used to guide the volume analysis. Conclusion : This study evaluated the developed computerized dose planning system of brachytherapy. The dose distribution was displayed on the coronal, sagittal and axial planes with the dose histogram. The accumulated DVH and 3D dose distributions provided by the developed system may be useful tools for dose analysis in comparison with orthogonal dose planning.

Indicators for the Quantitative Assessment of Tree Vigor Condition and Its Theoretical Implications : A Case Study of Japanese Flowering-cherry Trees in Urban Park (도시공원에 식재된 왕벚나무 수종을 중심으로 한 수목활력도의 정량평가지표 개발 및 이론적 고찰에 관한 연구)

  • Song, Youngkeun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.17 no.4
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    • pp.57-67
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    • 2014
  • The vigor condition of trees is an important indicator for the management of urban forested area. But difficulties in how to assess the tree vigor condition still remain. Previous efforts were limited in the 1) measurement of single indicator rather than using multiple indices, 2) purpose-oriented measurement such as for air-pollution effect or specific pathological symptom, and 3) ordinal-scale evaluations by field crews 4) despite human errors based on his/her experiences or prior knowledge. Therefore, this study attempted to develop a quantitative and objective methodology for assessing tree vigor condition, by measuring multiple modules and building the profile inventory. Furthermore, the possibility and limitations were discussed in terms of schematic frames describing tree vigor condition. The vigor condition of 56 flowering cherry plants in urban park were assessed by in-situ measurements of following eight items; growth of crown(Gc), growth of shoots, individual tree volume(Vol), plant area index, woody area index, leaf area index, leaf chlorophyll content(Lc) and leaf water content(Lw). For validation, these measurements were compared with the ranks of holistic tree vigor condition, which were visually assessed using a 4-point grading scale based on the expert's knowledge. As a result, the measures of each evaluation item successfully highlighted a variety of aspects in tree vigor condition, including the states of both photosynthetic and non-photosynthetic parts. The variation in the results depending on evaluated parts was shown within an individual tree, even though the broad agreement among the results was found. The result of correlation analysis between the tested measurements and 4-point visual assessment, demonstrated that the state of water-stressed foliage of the season (Lw) or the development of plant materials since sapling phase (Vol) could be better viewed from the outer appearance of trees than other symptoms. But only based on the visual assessment, it may be difficult to detect the quality of photosynthesis (Lc) or the recent trend in growth of trees (Gc). To make this methodology simplified for the broad-scale application, the tested eight measurements could be integrated into two components by principal component analysis, which was labelled with 'the amount of plant materials' and 'vigor trend', respectively. In addition, the use of these quantitative and multi-scale indicators underlies the importance of assessing various aspects of tree vigor condition, taking into account the response(s) on different time and spatial scale of pressure(s) shown in each evaluated module. Future study should be advanced for various species at diverse developing stages and environment, and the application to wide areas at a periodic manner.