• Archives of Pharmacal Research
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• 제24권6호
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• pp.564-567
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• 2001

The fecal ${\beta}-glucuronidase$ activity of patients with colon cancer and healthy controls were measured to determine the relationship between the fluctuation of intestinal bacterial ${\beta}-glucuronidase$ and colon cancer. The fecal ${\beta}-glucuronidase$ activity of patients with colon cancer was 1.7 times higher than that of the healthy controls. However, when these fecal specimens were sonicated, the enzyme activity of patients with colon cancer was 12.1 times higher than that of the healthy controls. The fecal ${\beta}-glucuronidase$ activity of human Intestinal bacteria was drastically induced by its substrate or the bile secreted after a subcutaneous injection of 1,2-dimethylhydrazine (DMH) and benzo[a]pyrene into rats. DMH-and benzo[a]pyrene-treated biles induced ${\beta}-glucuronidase$ activity in the human intestinal microflora by approximately 1.5- and 2.3-fold, respectively. They also induced ${\beta}-glucuronidase$ in E. coli HGU-3, which is a ${\beta}-glucuronidase$-producing bacterium from the human intestine. D-saccharic acid 1,4-lactone similarly inhibited fecal ${\beta}-glucuronidase$ in several patients with colon cancer in addition to the healthy controls. This suggests that potent ${\beta}-glucuronidase$ activity is a prime factor in the etiology of colon cancer.

• The Journal of Asian Finance, Economics and Business
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• 제8권12호
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• pp.485-496
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• 2021

This study explores the direct relationship between challenge and hindrance demands affecting autonomous extrinsic motivation and sales performance. In addition, we examine the mediating role of autonomous extrinsic motivation in the relationship between challenge demands, hindrance demands, and sales performance. This study explores the direct relationship between challenge and hindrance demands affecting autonomous extrinsic motivation and sales performance. In addition, we examine the mediating role of autonomous extrinsic motivation in the relationship between challenge demands, hindrance demands, and sales performance. This study proceeded in two phases comprising preliminary and prime research. First, preliminary quantitative research was conducted through face-to-face interviews with 125 observations to analyze the reliability of the scale and exploratory factor analysis to evaluate the measurements. The data collected from 431 real estate market employees shows that both challenge and hindrance demands positively and negatively affect sales performance through autonomous extrinsic motivation. Furthermore, challenge demands and hindrance demands affect positive and negative sales performance through autonomous extrinsic motivation, respectively. This study suggests that business organizations should design job demands to ensure that challenging work is suitable for employees' job positions. Thus, they will contribute to motivation and help employees achieve job performance.

• Safety and Health at Work
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• 제12권4호
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• pp.452-461
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• 2021

Background: The prevailing global work scenario and deteriorating health facilities in economies indulge the risk perspective in the labor market model. This is the reason that the risk factor is cautiously attributed to wages and labor market efficiencies specifically in developing and emerging economies. In this respect, Occupational Injuries of Workers (OIW) is considered essential to demonstrate the risk and Occupational Health and Safety (OHS) setups given the constraints of the labor. Intuitively, the prime objective of this study is to make an assessment of the labor market considering the OIW through the indicators of industry division, employment status, occupational distribution, adopted treatment, gender and regionality. Methods: The assessment strategy of the study has been categorized into trend analysis and Index Value Calculation (IVC) segments employing the data from 2001 to 2018. Results: The pattern of the selected indicators of the OIW has been observed in the available data while the IVC estimations are considered through time and reference categories. The findings of both exercises revealed absolute and relative heterogeneities at both industry and occupational levels. Conclusion: The consistency for gender and regional distribution of both assessments points out the need for effective policy initiatives. The study suggests separate analyses of industry and occupations for a better understanding of the OHS setups and up-gradation in Pakistan.

• Restorative Dentistry and Endodontics
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• 제46권3호
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• pp.32.1-32.10
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• 2021

Objectives: This study aimed to evaluate the effect of the application method of universal adhesives on the shear bond strength (SBS) of repaired composites, applied with different thicknesses. Materials and Methods: The 84 specimens (Filtek Z350 XT) were prepared, stored in distilled water for a week and thermocycled (5,000 cycles, 5℃ to 55℃). They were roughened using 400-grit sandpapers and etched with phosphoric acid. Then, specimens were equally divided into 2 groups; Single Bond Universal (SU) and Prime&Bond Universal (PB). Each group was subdivided into 3 subgroups according to application methods (n = 14); UC: 1 coat + uncuring, 1C: 1 coat + curing, 3C: 3 coats + curing. After storage of the repaired composite for 24 hours, specimens were subjected to the SBS test and the data were statistically analyzed by 2-way analysis of variance and independent t-tests. Specimens were examined with a stereomicroscope to analyze fracture mode and a scanning electron microscope to observe the interface. Results: Adhesive material was a significant factor (p = 0.001). Bond strengths with SU were higher than PB. The highest strength was obtained from the 1C group with SU. Bonding in multiple layers increased adhesive thicknesses, but there was no significant difference in SBS values (p = 0.255). Failure mode was predominantly cohesive in old composites. Conclusions: The application of an adequate bonding system plays an important role in repairing composite resin. SU showed higher SBS than PB and the additional layers increased the adhesive thickness without affecting SBS.

• 가족자원경영과 정책
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• 제16권1호
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• pp.85-101
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• 2012

This study aims to identify the propensity to consume and housing characteristics according to life cycle as the main independent variable. It also tries to understand the consumption power and housing style of each cycle and analyze whether there are differences between each life cycle, ultimately aiming to match the propensity to consume and housing style with each cycle. For empirical analysis, on and off-line surveys of 488 people were collected and analyzed by cross analysis, factor analysis and analysis of variance. The prime research findings are as follows: First of all, factor analysis on propensity to consume showed four main sub-factors as rational consumption, conspicuous consumption, trend consumption, and status consumption. Secondly, current and preferred housing styles ranked from modern, natural, casual, classic and romantic, which proved that people are currently housed in preferred housing styles. Thirdly, in case of housing-related characteristics of life cycles, the size of the house increased as the levels progressed, and then decreased at level 6 when the children grew into adulthood. The majority of the population was paying a monthly rent, a few were leasing, and a very few owned their housing. 58% were living in apartments, but in levels 1-2, more were living in row houses and high-rise residential buildings, while in level 6 it was detached houses. Fourthly, the propensity to consume according to life cycle tended to shift from conspicuous and trend-based consumption to rational consumption as the cycles progressed. Fifthly, the preferred housing styles were modern and natural styles, regardless of life cycle. These study results can be applied to product development and marketing activities based on their accurate analysis of customers' needs, which can thus bring further customer satisfaction.

• 대한기계학회논문집
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• 제14권1호
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• pp.112-118
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• 1990

본 연구에서는 ASTM-E24.01.06에서 제안하고 있는 실험방법을 응용하여 균열 정지 파괴인성값을 측정하였다.즉 쐐기와 분리형 부싱(wedge and split bushing)으 로 압축하중을 가함으로 균열선 웨지하중 시편[crack line wedge loaded specimen(CL- WL시편)]에 인장력을 발생시켜서 균열정지 응력확대계수( $K_{1a}$)를 결정하였다. 그리고 균열개시 응력확대계수가 균열정지 응력확대계수에 미치는 영향들을 여러가지 재료들에 대하여 체계적으로 검토하였다.다.

• 한국환경과학회지
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• 제19권8호
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• pp.1057-1066
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• 2010

An ecological learning center is defined as a place which can establish the correct relationship between human and environment. Human can learn ecosystem and importance of environment throughout observation of nature and participation in program of ecological learning center. The most important aspects of ecological learning center planning are to reflect on user's demand and preservation of ecosystem. The prime goals of this study is to analyze user's characteristics in the Young Wheol Mulmurigol Ecological Learning Center. The second goal of this study is to find out the satisfaction model based on user's perceived performance of each program and facility in the center. For this study, questionnaire survey with 204 individuals was completed. The data from the questionnaire were analyzed statistical method by SPSS. There are several significant results from the study as following First, this ecological learning center as a newly operating facility is used not for educational purpose but for resting and relaxation purpose. It is due to that the most of users in this center are package tourists with historic scenes. Second, user's perceived performance evaluated by 23 attributions of programs and facilities, and these attributions could be classified by 5 factors such as environment friendly design, educational function, preservation of environment, provision of various bio-top and provision of resting area. Third, the user satisfaction model indicates that user satisfaction is depended on various factors such as preservation of environment, provision of various bio-top, provision of resting area. Among these factor affecting the satisfaction, provision of various bio-top is the most influence on user satisfaction.

• 한국자동차공학회논문집
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• 제16권1호
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• pp.8-13
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• 2008

Emissions from automobiles have long been considered a prime source of pollutants involved in smog formation and ozone production. Especially VOCs are associated with serious environmental problems such as photo-chemical smog as well as human health effects. Since motor vehicles are a major source of VOCs, estimating of emission from mobile source is the most important factor to control VOCs. VOCs are emitted from various pollution like motor vehicles, mobile and stationary source that has characteristics of toxicity, cancer-causing, bio-accumulation, durability in air and diffusion can exert a bad influence upon human health and environment. However we don't have any standard or regulation about VOCs emissions. This study is summarized as VOCs emission characteristics from in-use light-duty diesel and LPG fueled vehicles. The vehicle exhaust-gas test mode is CVS cycle and nier-10 cycles that developed on EPA and National Institute of Environmental Research. TO-14 method (Toxic Organic) was chosen for VOCs analysis from EPA in USA. This study results will be useful when make a emission factor and rule making of emission standard about domestic VOCs emission for the improve to air condition.

• 한국산업보건학회지
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• 제27권2호
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• pp.123-129
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• 2017

Objectives: The purpose of this study is to enhance the application of analytical method of polar solvents(alcohols) by GCOTC (gas chromatography open tubular column) through the system suitability test(SST) to estimate the whole chromatographic system performance(integral part). Methods: To perform the SST, carried out repeatability(n=6) as analytical method of polar solvents by GCOTC, got the retention time($t_R$), standard deviation(${\sigma}_{n-1}$) of $t_R$, baseline width($w_b=4{\sigma}_{n-1}$) and calculated dead time($t_m$) by $v_m=d^2{\pi}L(f/4)$ and $v_m=t_m$ x flow rate. Results: In this experiment, obtained the basic data, there were $t_m=2$ min, methanol($t_R=3.569$, ${\sigma}_{n-1}=0.01$, $w_b=0.04$), ethanol ($t_R=3.892$, ${\sigma}_{n-1}=0.004$, $w_b=0.016$), isopropanol($t_R=4.209$, ${\sigma}_{n-1}=0.004$, $w_b=0.016$). By using these data, calculated the corrected retention time($t_R{^{\prime}}$), capacity factor(k), separation factor(${\alpha}$), number of theoretical plate(n) and resolution($R_s$) for SST and got the good results. Conclusions: Through the SST, could reconfirm the whole chromatographic performance system(integral part) for analytical method of polar solvents by GCOTC. Therefore, this analytical method expect to be widely applied at the related areas.

• 한국콘텐츠학회논문지
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• 제17권1호
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• pp.183-192
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• 2017

본 연구는 흡연자와 비흡연자 모두를 위해 담배 연기로 인한 피해를 최소화하고 사용자에게 편안함을 줄 수 있는 흡연 부스를 디자인하기 위함이다. 연구방법으로 첫째, 흡연부스에 대한 의식조사, 둘째 제품 디자인에 대한 선호도조사, 셋째 감성어휘에 의한 흡연부스 감성평가 조사를 하였다. 흡연부스에 대한 의식조사결과, 대부분 모든 사람들이 터미널, 역에 흡연부스가 필요하다고 하였다. 디자인 선호도에 조사결과로 첫째, 외부 흡연자를 위한 디자인부스는 딱딱하고 투박한 이미지 보다는 멀리서도 알기 쉽고 거부감이 들지 않는 형태의 디자인으로 제작되어져야 한다. 둘째, 원색 계열의 색상보다는 화이트와 파스텔 톤의 난색계열 및 밝은 색상을 적용하여 디자인한다. 셋째, 흡연부스이므로 내부 순환 필터 문제가 잘 관리 될 수 있도록 한다. 감성어휘에 의한 감성평가결과 자극물에 대하여 4가지 차원으로 구분하여 인지하고 있었다. 각 인자의 함축 언어로 1인자에 대한 대표 이미지 언어는 '기능적 감정' 2인자의 대표 이미지 언어는 '심리적감정' 3인자의 대표 이미지 언어는 '색상감정' 4인자의 대표 이미지 언어는 '형태감정'으로 정의하였다. 흡연자와 비 흡연자 양쪽 모두를 위해 담배연기로 인한 피해를 최소화 시킬 수 있어야 하며 혼자만의 휴식을 취할 수 있는 사용자 중심의 서비스 디자인이 필요하다.