• 한국임상수의학회지
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• 제39권4호
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• pp.162-167
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• 2022

To determine the prevalence of breed, age, and sex of canine primary glaucoma by comparing previous reports in Korea. We included the medical records of dogs diagnosed with primary glaucoma who visited the veterinary medical teaching hospital of Seoul National University (SNU) from January 2011 to December 2020 and investigated their breed, age, and sex. All the patients underwent a full ophthalmic examination. We analyzed the results using a binary logistic regression analysis based on the Jindo dog, which was close to the mean value of the primary glaucoma incidence rate. Of the 14,587 dogs treated at the veterinary medical teaching hospital of SNU, 107 (0.73%) were diagnosed with primary glaucoma. Glaucoma occurred in 14 breeds, including the American Cocker Spaniel, Shih Tzu, Maltese, Pomeranian, Jindo dog, Mixed Breed, Pekinese, Toy Poodle, Samoyed, Shiba Inu, Miniature Pinscher, Boston Terrier, Labrador retriever, and Yorkshire Terrier. The mean age of onset of primary glaucoma was 7.8 ± 2.3 years. Primary glaucoma was observed in 53 spayed females, 11 females, 38 castrated males, and five males. Regardless of neutralization, the ratio of females to males was 1.5:1. This study showed that primary glaucoma was significantly higher in American Cocker Spaniels and higher in Shih Tzus than other breeds in Korea; they had the highest incidence of primary glaucoma at 7 and 8 years of age, respectively. Therefore, the two breeds should be carefully monitored for the occurrence of primary glaucoma when they approach 7 years of age.

• Journal of Korean Neurosurgical Society
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• 제48권2호
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• pp.145-152
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• 2010

Objective : The aim of this report is to provide accurate nationwide epidemiologic data on primary central nervous system (CNS) tumors in Korea. Despite its importance, there are no accurate statistics on primary CNS tumors in Korea. We analyzed primary CNS tumors diagnosed in 2005 from the nationwide registry. Methods : Data on primary CNS tumors diagnosed in 2005 were collected from the Korean Central Cancer Registry and the Korean Brain Tumor Society. Crude and age-standardized rates were calculated in terms of gender, age, and histological type. Tumors of uncertain histology were investigated individually at the corresponding hospitals and had their diagnoses confirmed. Results : A total of 5,692 patients diagnosed with primary CNS tumors in 2005 were included in this study. CNS tumors occurred in females more often than in males (female to male, 1.43 : 1). The most common tumor was meningioma (31.2%). Glioblastoma accounted for 30.7% of all gliomas, and 19.3% of all malignant primary CNS tumors. In children under 19 years of age, both germ cell tumor and embryonal/primitive/medulloblastoma were the most common tumors. Conclusion : This article is the first nationwide primary CNS tumor epidemiology report in Korea. Data from this study should provide valuable information regarding the understanding of primary CNS tumors epidemiology in Korea.

• 정보관리학회지
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• 제22권4호통권58호
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• pp.173-195
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• 2005

본 연구는 언어적 난이도에 영향을 주는 요인들로 텍스트수준점수 측정공식을 구성하는 방법론이 초등학교 텍스트는 물론 중고등학교 텍스트까지 확장 ·적용될 수 있는지 확인하고 텍스트가 확장됨에 따라 나타나는 새로운 특성을 설명할 수 있는 요인들을 규명하고자 한다. 초중고 텍스트 통합공식, 중고등학교 텍스트 전용공식, 초등학교 텍스트 전용공식을 구성하여 각 공식들의 특징을 비교한 결과 텍스트의 범위를 넓게 잡아 통합 공식을 구성하는 것보다는 소규모 집단으로 분리한 후 전용공식을 구성하는 것이 해당 집단의 특성을 잘 반영하는 우수한 공식을 도출할 수 있는 것으로 확인되었다. 중고등학교 텍스트의 점수를 측정하려면 단락내문장수요인, 문장수 $\cdot$ 단락수요인을 사용하고 초등학교 텍스트의 점수를 측정하려면 이형어절수요인, 이형어절수$\cdot$새어절출현비율요인을 사용하는 것이 효율적이었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9335-9339
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• 2014

Background: To determine the frequency of primary circulating prostate cells (CPC) detection according to age and serum PSA levels in a cohort of men undergoing screening for prostate cancer and to determine the diagnostic yield in those men complying with the criteria for prostate biopsy. Materials and Methods: A prospective study was carried out to analyze all men evaluated in a hospital prostate cancer screening program. Primary CPCs were obtained by differential gel centrifugation and detected using standard immunocytochemistry using anti-PSA, positive samples undergoing a second process with anti-P504S. A malignant primary CPC was defined as PSA+ P504S+, and a test positive if 1 cell/4ml was detected. The frequency of primary CPC detection was compared with age and serum PSA levels. Men with a PSA >4.0ng/ml and/or abnormal rectal examination underwent 12 core prostate biopsy, and the results were registered as cancer/no-cancer and compared with the presence/absence of primary CPCs to calculate the diagnostic yield. Results: A total of 1,117 men participated; there was an association of primary CPC detection with increasing age and increasing serum PSA. Some 559 men underwent initial prostate biopsy of whom 207/559 (37.0%) were positive for primary CPCs and 183/559 (32.0%) had prostate cancer detected. The diagnostic yield of primary CPCs had a sensitivity of 88.5%, a specificity of 88.0%, and positive and negative predictive values of 78.3% and 94.9%, respectively. Conclusions: The use of primary CPCs for testing is recommended, since its high negative predictive value could be used to avoid prostate biopsy in men with an elevated PSA and/or abnormal DRE. Men positive for primary CPCs should undergo prostate biopsy. It is a test that could be implemented in the routine immunocytochemical laboratory.

• Journal of Chest Surgery
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• 제22권2호
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• pp.246-255
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• 1989

A total and consecutive 291 patients of isolated single mitral valve replacement using the Ionescu-Shiley bovine pericardial xenograft valve operated on between October 1978 and June 1983 were retrospectively studied for the durability of the substitute valves based on the structural degeneration of primary tissue failure which had been proved on their re-replacement surgery. The mean age at the initial surgery was 32.4*12.5 years, and the operative mortality rate was 5.2 %. The early survivors of 276 patients were followed up for a total 1148.3 patient-years[mean\ulcornerD, 4.16*2.57 years]at the follow-up end of June 1988. They experienced 4 major late complications: 1.045 % thromboembolism/patient-year [pt-yr]; 0.871 % bleeding/pt-yr; 0.610% endocarditis/pt-yr; and 3.309% overall valve failure/pt-yr or 1.655% primary tissue failure/pt-yr. The actuarial survival rates were 89.4*2.2% and 87.7*2.5% at 5 and 10 years after initial surgery respectively. The probabilities of freedom from thromboembolism were 95.1*1.6% and 93.2*2.0% at 5 and 10 years after surgery. Nineteen patients underwent re-replacement of the Ionescu-Shiley valve because of primary tissue failure, and there was no operative mortality. The incidence of primary tissue failure was highest for the patients less than 15 years of age occurring in 9 out of 27 patients [33.3 %] or 8.68 %/pt-yr, while it was 4.0 % or 0.96 %/pt-yr for the rest of patients older than this age. The probabilities of freedom from primary tissue failure were 96.7*1.4 % and 84.2*3.8% at 5 and 9 years after surgery. The freedom from tissue failure increased as the age limits of cumulative younger patients were increased while it decreased as the age limits of cumulative older patients were decreased. Although it is clear that the Ionescu-Shiley valve would degenerate prematurely in young patients, the definite age limit could not be identified when the risk of early failure was significantly high.

• Journal of Preventive Medicine and Public Health
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• 제56권3호
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• pp.248-254
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• 2023

Objectives: Measuring the quality of care is paramount to inform policies for healthcare services. Nevertheless, little is known about the quality of primary care and acute care provided in Korea. This study investigated trends in the quality of primary care and acute care. Methods: Case-fatality rates and avoidable hospitalization rates were used as performance indicators to assess the quality of primary care and acute care. Admission data for the period 2008 to 2020 were extracted from the National Health Insurance Claims Database. Case-fatality rates and avoidable hospitalization rates were standardized by age and sex to adjust for patients' characteristics over time, and significant changes in the rates were identified by joinpoint regression. Results: The average annual percent change in age-/sex-standardized case-fatality rates for acute myocardial infarction was -2.3% (95% confidence interval, -4.6 to 0.0). For hemorrhagic and ischemic stroke, the age-/sex-standardized case-fatality rates were 21.8% and 5.9%, respectively in 2020; these rates decreased since 2008 (27.1 and 8.7%, respectively). The average annual percent change in age-/sex-standardized avoidable hospitalization rates ranged from -9.4% to -3.0%, with statistically significant changes between 2008 and 2020. In 2020, the avoidable hospitalization rates decreased considerably compared with the 2019 rate because of the coronavirus disease 2019 pandemic. Conclusions: The avoidable hospitalization rates and case-fatality rates decreased overall during the past decade, but they were relatively high compared with other countries. Strengthening primary care is an essential requirement to improve patient health outcomes in the rapidly aging Korean population.

• 대한소아치과학회지
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• 제27권1호
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• pp.122-134
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• 2000

각화치은, 부착치은의 폭경, 치은열구의 깊이에 대해 성인에서는 많은 연구가 있었으나 아동에서의 연구는 드물었기 때문에, 유치열기, 혼합치열기 및 영구치열기의 모든 치아에 대하여 아동의 협측 각화치은 및 부착치은의 폭경과 치은열구 깊이에 대한 정상치를 구하고, 악골의 발육 및 치아의 맹출과의 관련성을 고찰하며, 점막치은 문제의 발현빈도를 조사하고자 하였다. 결론은 다음과 같다. 1. 유치열의 부착치은 폭경은 상악 유측절치 및 유견치에서 각각 3.50mm, 3.55mm로 최대값을, 하악 제1유구치에서 1.34mm로 최소값을 나타내었다. 영구치열의 경우에는 상악 측절치에서 3.00mm로 최대값을, 하악 제1소구치에서 0.55mm로 최소값을 나타내었다. 상하악 동명치아 비교시 상악 치아가 하악 치아보다 더 큰 값을 나타내었고, 남녀간 차이에는 특별한 규칙이 발견되지는 않았다. 2. 연령증가에 따른 부착치은 폭경의 변화 양상은 유치열의 경우 유견치, 제1유구치, 제2유구치에서 6세부터 증가하였다. 영구치의 경우 남자에서는 하악 중절치와 상악 제 1대구치의 측정값만이 연령에 따른 증가 추세를 나타냈으나(p<0.05), 여자에서는 상하악 중절치 측절치 및 상악 제1대구치에서 통계적으로 유의성 있는 각화치은 폭경의 증가 추세를 관찰할 수 있었다(p<0.05). 3. 치아교대기에서 부착치은 폭경의 차이는 남자 상악 중절치를 제외한 모든 경우에 유치에서의 측정값이 영구치에서의 측정값보다 큰 것으로 나타났다(p<0.05). 4. 6제부터 12세까지는 각화치은의 폭경과 치은열구의 깊이는 대부분 유치 초기값보다 그 계승영구치 최종값이 더 높은 값을 나타냈으나(p<0.05), 부착치은의 폭경에서는 유치 초기와 그 계승영구치 최종값사이에 통계적으로 유의성 있는 차이가 나타나지 않았다. 5. 점막치은 문제 발현 빈도는 남녀에 상관없이 유치열은 상하악 제 1유구치가, 영구치열은 상하악 모두 제 1소구치가 최고치를 나타냈으며 유치에서보다 그 대응 계승영구치에서 그 빈도가 더욱 높게 나타났다. 연령증가에 따라 점막치은 문제의 발현 빈도는 유치열, 영구치열에서 모두 감소하였으나, 하악 제1유구치, 하악 영구 견치, 제1, 제2소구치의 경우 연령의 증가와 상관없이 비슷하게 유지되거나 증가하는 경향을 보였다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1209-1214
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• 2016

Background: Cigarette smoking constitutes a major threat to the health and wellbeing of teenagers. While smoking has been on decline in the developed countries, the reverse is the case in developing countries. The aim of this study was to determine the age of initiation, determinants and prevalence of cigarette smoking among teenagers in Mushin Local Government Area of Lagos state, Nigeria. Materials and Methods: This was a descriptive cross-sectional study among 475 teenagers selected by multistage sampling. A pre-tested, structured, interviewer-administered questionnaire was used for data collection. The study was carried out in November, 2014. Results: Response rate was 84.6%. Mean age of the respondents was $16.4{\pm}1.65years$. Range and mean age of initiation of cigarette smoking were 7 to 17 years and $12.0{\pm}3.32years$ respectively. Teenagers who were above 15 years (OR:5.13, 95%CI: 0.87-30.26), males (OR:5.19, 95%CI: 1.57-17.18), married (OR:8.41, 95%CI: 1.04-63.35), had ${\leq}$primary school education(OR:4.31, 95%CI: 1.07-17.33), influenced by friends(OR:308.84, 95%CI:84.87-1123.81), and influenced by advertisements (OR:27.83, 95%CI: 3.92-197.64) were more likely to have initiated cigarette smoking. Furthermore, teenagers who were males (OR:12.77, 95%CI: 2.90-56.28), married (OR:19.24, 95%CI: 2.05-180.45), had ${\leq}$primary school education(OR:7.85, 95%CI: 2.37-26.01), influenced by friends(OR:28.56, 95%CI: 10.86-75.07), and influenced by advertisements (OR:5.95, 95%CI: 1.72-20.61) were more likely to be current cigarette smokers. In addition, 24.9% had initiated cigarette smoking while 14.7% were current smokers of cigarette. Conclusions: Mean age of initiation of cigarette smoking was $12.0{\pm}3.32years$. Determinants of cigarette smoking were age, gender, marital status, educational background, friends and advertisements. Life time prevalence of cigarette smoking was higher than prevalence of current cigarette smokers. Cigarette smoking reduction programs should take these factors into consideration.

• 대한소아치과학회지
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• 제8권1호
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• pp.65-75
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• 1981

The author have studied on the pulp responses to the electric pulp stimulator (Pyo-Cure)(R) in the primary molar age from 4 to 11 of the 186 children (male 100, female 86). The total numbers of teeth used in this study were 1096. The results were as follows ; 1. The difference in responses between the teeth of the male and female was not statistically significant. 2. The difference in responses between the teeth of the right and left sides was not statistically significant. 3. The difference in responses between the teeth of the upper and lower jaws was not statistically significant. 4. The responses of the teeth in the older age is higher than its of the early age. 5. Inspite of advanced root resorption of the primary molars, except severe root resorption, the responses of the teeth was higher according to increasing the age. 6. The responses of the teeth were decreased severely in the primary molars as it becomes exfoliation time.

• 대한간호학회지
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• 제3권3호
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• pp.73-77
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• 1973

A study on the nutritional status for school-children has been carried out 1,700 school- children of Song-do primary school located in Song-do beach, Busan, Korea, from November to-December, 1972. The evaluation of the nutritional status has been carried out through skin-fold thickness and hemoglobin. The summarized results were as follows. : 1. Skinfolds thickness 1) Subcellular skinfolds thickness . Among boys, that was 3.5mm in the age 6 and 5.4mm in the age 11 Among girls, that was 4.2mm in the age 6 and 7.6mm in the age 11. Girls were thicker than toys in the all age. 2) Upper-arm skinfolds thickness Among boys, that was 5.0mm in the age 6 and 6.8mm in the age 11. Among girls, that was 6.2mm in the age 6 and 8.7mm in the age 11. Girls were thicker than toys in the all age. 3)Abdominal skinfolds thickness. Among boys, that was 4.0mm in the age 6, and 6.4mm in the age 11. Among girls that was 4.0mm in the age 0, and 8.4mm in the age 11. Girls were thicker than boys in the all age. 2. Hemoglobin Proportional range of hemoglobin were observed as 12.2-12.8 gm/㎗.