• Journal of Periodontal and Implant Science
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• v.51 no.1
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• pp.63-74
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• 2021

Purpose: This study investigated the effects of hyaluronic acid (HA) on peri-implant clinical variables and crevicular concentrations of the proinflammatory biomarkers interleukin (IL)-1β and tumor necrosis factor (TNF)-α in patients with peri-implantitis. Methods: A randomized controlled trial was conducted in peri-implantitis patients. Patients were randomized to receive a 0.8% HA gel (test group), an excipient-based gel (control group 1), or no gel (control group 2). Clinical periodontal variables and marginal bone loss after 0, 45, and 90 days of treatment were assessed. IL-1β and TNF-α levels in crevicular fluid were measured by enzyme-linked immunosorbent assays at baseline and after 45 days of treatment. Clustering analysis was performed, considering the possibility of multiple implants in a single patient. Results: Sixty-one patients with 100 dental implants were assigned to the test group, control group 1, or control group 2. Probing pocket depth (PPD) was significantly lower in the test group than in both control groups at 45 days (control 1: 95% CI, -1.66, -0.40 mm; control 2: 95% CI, -1.07, -0.01 mm) and 90 days (control 1: 95% CI, -1.72, -0.54 mm; control 2: 95% CI, -1.13, -0.15 mm). There was a trend towards less bleeding on probing in the test group than in control group 2 at 90 days (P=0.07). Implants with a PPD ≥5 mm showed higher levels of IL-1β in the control group 2 at 45 days than in the test group (P=0.04). Conclusions: This study demonstrates for the first time that the topical application of a HA gel in the peri-implant pocket and around implants with peri-implantitis may reduce inflammation and crevicular fluid IL-1β levels.

• Journal of Korean society of Dental Hygiene
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• v.12 no.4
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• pp.695-705
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• 2012

Objectives : The purpose of this study is to evaluate the appearance of having relationship between the exposure to lead and cadmium and the dental caries targeting adults in the Republic of Korea. Methods : The study was designed as a cross-sectional study, using the data of the Fourth Korea National Health and Nutrition Examination Survey. The subjects as 1,966 people, who were confirmed the appearance of dental caries among 1,991 people of having been offered the heavy-metal concentration in blood. Statistical analysis was conducted using SPSS 19.0, according to complex sampling design. Results : As a result of multi-variate analysis on factors of dental caries, in Model I without correction, the gender, age, educational level, appearance of lifelong smoking, daily toothbrushing frequency, appearance of using dental floss, and subjective oral health status were recognized as important factors. In Model II with correction of gender and age, the educational level, daily toothbrushing frequency, and subjective oral health status were recognized as statistically significant factors. In Model III with correction of all factors, the gender, age, educational level, appearance of using dental floss, and subjective oral health status were functioning as statistically significant factors. As a result of statistically analyzing relationship between the exposure to lead and cadmium and the dental caries targeting adults, it was analyzed that there is no significant correlation. However, in case of lead, the tendency of being grown the cross ratio of dental caries could be examined in model I, which didn't correct disturbance factor, model II, which corrected gender and age, and model III, which corrected all variables of disturbance factor. Conclusions : The exposure to lead and cadmium was indicated to have no relationship with adults' dental caries. However, a continuous research of relationship was considered to be necessary by using Korea National Health and Nutrition Examination Survey, which is surveyed in the future.

• Journal of Preventive Medicine and Public Health
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• v.39 no.2
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• pp.135-140
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• 2006

Objectives : Polymorphisms of genes from glutathione Stransferases (GSTs) and N-acetyltransferase 2 (NAT2) have been associated with increased susceptibility to various cancers. Previous results showed that East Asians such as Koreans, Japanese and Chinese have a much higher frequency of the GSTM1 and GSTT1 null genotypes and NAT2 rapid acetylator type. Therefore, we investigated the association between the polymorphic types of GSTs (GSTM1, GSTT1, GSTP1) and NAT2 and the incidence of gastric cancer which is one of the most prevalent cancers among the East Asians. Methods : It was performed in a case-control study consisting of 238 healthy subjects and 108 cancer patients (54 distal and 54 proximal carcinomas). We also evaluated the association between GSTs and NAT2 and the risk factors for gastric cancer such as alcohol consumption, smoking, H. pylori infection, family history of gastric cancer, and tumor location. Results : In our study, the percentage of cases whose hometown was rural was higher than those of controls (odds ratio (OR) =2.88; 95% CI=1.72-4.76), and the frequency of the lower socio-economic status increased significantly in patients (OR=2.53; 95% CI=1.59-4.02). There was no significant difference in the GST polymorphic types between the cases and controls. However, NAT2 rapid or intermediate acetylator types were frequently detected in the cases with family history of gastric cancer (OR=1.92; 95% CI=1.79-26.0). Conclusions : These results suggest that the hometown and socio-economic status are important environmental factors for gastric carcinogenesis, and NAT2 polymorphic types could be associated with familial gastric carcinoma.

• Journal of Korean society of Dental Hygiene
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• v.11 no.6
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• pp.893-900
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• 2011

Objectives : The study was to examine satisfaction with their major study influences their perception of occupational consciousness among dental hygiene freshmen. Methods : The total of dental hygiene freshmen were conveniently recruited from four schools located in Gyeongsangnam-do, Ulsan and Busan city. A questionnaire was used to collect information about general characteristics and the perception of occupational consciousness and major study satisfaction. The statistical analysis was done by using the SPSS 18.0 program. Results : Dental hygiene freshmen who showed a positive their major satisfactory showed higher perception of occupational. The social recognition and position of job-consciousness was lowest at the score 2.55, harmony with a colleague is close to efficiency in duty of job-consciousness was highest at the score 3.54. Conclusions : We need a modifying and complement of the career guidance programs for dental hygiene freshmen.

• The Journal of the Korean dental association
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• v.51 no.9
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• pp.511-517
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• 2013

To assess the association between oral health and general health, this study examined the relationship between chewing difficulty and twelve chronic health conditions such as hypertension, hyperlipidemia, diabetes, cerebro- and cardiovascular disease, musculoskeletal disease, respiratory disease, eye/nose/throat disease, stomach/intestinal ulcer, renal dysfunction, thyroid disease, depression, and cancer in Korea. The study population was 3,066 elders aged 65 years old and more from the fourth Korean National Health and Nutrition Examination Survey. Chewing difficulty was measured on a 5-point Likert scale. Chronic conditions were assessed by self-reported questionnaire. Confounders were age, gender, education, income, smoking, drinking, and obesity. Chi-square test, general linear model, and multiple logistic regression model were done with complex sampling design. Musculoskeletal disease (adjusted odds ratio=1.33), respiratory disease (adjusted odds ratio=1.52), and cancer (adjusted odds ratio=1.58) were independently associated with chewing difficulty. Multiple chronic conditions with more than 4 chronic disease showed significant association with chewing difficulty (adjusted odds ratio=1.37).

• The Journal of the Korean dental association
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• v.9 no.4
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• pp.151-157
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• 1971

Freshly extracted permant teeth were examined by electron microscope according to the Filmy replica method. Preparatory method with hydrochloric acid or proteolytic enzyme treatment was used in order to injure the structural composition of enamel surface to compare between the natural carious defects and the etched samples used in this study. The natural carious defects were chalky white or brown discolored portions at the smooth enamel surface without having visible loss of enamel substances. The findings were as follows: 1. The first caries attact initiated from the mineralized portion of rod sheath which is located at the top of enamel rod. 2. The caries developed downward along the rod sheath interprismatic substances and enamel rods subsequently. However, the caries involvement of interprismatic substances and enamel rods occured almost at the same time. 3. The rod sheath attached to the remineralized smooth emael surface was located at the top of enamel rod.

• The Journal of the Korean dental association
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• v.49 no.8
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• pp.451-460
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• 2011

Dental caries has been widely prevalent with presence of cavitation on teeth. For the last several decades, the prevalence of dental caries in developed countries has rapidly decreased so there has been needed a new and detailed diagnostic guideline to differentiate the severity of dental caries, especially for early status of caries. The cariology specifically requires the development of an integrated definition of dental caries and uniform systems for measuring the caries process in the fields of clinical diagnosis and treatment, epidemiological researches, and dental education and so forth. The international Caries Detection and Assessment System (ICDAS) optically measures the enamel surface changes and potential histological depth of carious lesions by relying on surface characteristics of teeth. ICDAS is a visual classification system that was developed to diagnose the subtle changes of enamel surface, predict the progress direction of early caries, allow standardized data collection in relation to caries in different settings, and to enable better comparison of oral health between countries worldwide and research studies.

• The Journal of the Korean dental association
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• v.50 no.9
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• pp.552-557
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• 2012

Bamboo salt is a special processed salt by Korean traditional recipe. Recent study results showed that bamboo salt or bamboo salt with some other materials like herbal extracts have the anti-microbial activity, inhibition effects of dental plaque and gingival inflammation. Bamboo salt also showed anti-cariogenic effects; remineralization and acid resistance. Compare to fluoride toothpaste, bomboo salt toothpaste with fluoride showed the more effective remineralization on inner part of the early dental caries lesion. It increased the surface hardness and decreased lesion depth of early dental caries lesion. Thus, it is suggested thai bamboo salt could be used as a anti-microbial, anti-plaque, anti-inflammatory and anti-cariogenic material for oral disease prevention. Especially, bamboo salt dentifrice with fluoride can be recommanded as a useful remineralizing agent.

• The Journal of the Korean dental association
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• v.55 no.2
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• pp.172-179
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• 2017

Since early model of powered toothbrush (Broxadent) was introduced in the 1960s, the design of powered toothbrush has changed significantly. Today powered toothbrushes can be categorized as mechanical and sonic. The main patterns of movements in the modern powered toothbrushes are oscillation, reciprocation, and rotational. Powered brushes especially helpful for people who have disabilities or dexterity issue. These brushes are also highly recommended for patients who require a larger handle because these are easier to grasp. By systematic review of Cochrane group in 2014, powered toothbrushes reduced dental plaque and gingivitis more than manual toothbrushing in the short and long term. Now we can recommend powered toothbrushes to people who need to enhance self-control dental plaque removal efficacy.

• The Journal of the Korean dental association
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• v.55 no.2
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• pp.166-171
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• 2017

Periodontitis is the major concern of oral disease to human, and begins in the interdental area. The aim of this study is to discuss the clinical application method and the meaning of interdental brush. It is very difficult to change oral health behaviors, because patients believe that it is enough that the reason of tooth brushing is to remove food debris, not dental biofilm. Moreover, there are several barriers for using interdental brush. For the better oral health and maintenance of dental prosthesis, it is very important to motivate the use of the interdental brush well, and teach the desirable design of the interdental brush and the clinical meaning to patients.