• Journal of Digital Convergence
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• v.12 no.4
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• pp.349-356
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• 2014

This research is aimed to prove if harmful effects of smoking, as the main reason for recently elevated blood vessel disease, could be reduced by aerobic exercise, and identify the positive effects of the aerobic exercise on smokers' blood vessel health(blood pressure, pulse pressure, and blood vessel elasticity. Experiments were performed on 40 male smokers aged between 40 and 55, which was equally divided into two groups of Aerobic Exercise Group (AEG) and Non Exercise Group (NEG). After measuring each group's blood pressure, pulse pressure, and blood vessel elasticity, AEG practiced aerobic exercise program for 50 minutes for each trial, three times a week, sustaining 12 weeks while NEG continued daily-life patterns without any special treatment. In 12 weeks, blood pressure, pulse pressure, and blood vessel elasticity of both groups were measured as the same way. As a result, the difference of systolic blood pressure between the two groups was not significant, while that of diastolic blood pressure was meaningful. The difference of pulse pressure between the two groups was meaningful, and that of blood vessel elasticity was also meaningful in all measuring points including left hand, right hand, left foot and right foot. As a consequent, it was found that aerobic exercise had positive effects on middle aged male smokers' blood vessel health.

• Wind and Structures
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• v.30 no.1
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• pp.37-54
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• 2020

To investigate the motion-induced aeroelastic effects (or aerodynamic feedback effects) on a square cylinder in uniform flow, a series of wind tunnel tests involving the pressure measurement of a rigid model (RM) and simultaneous measurement of the pressure and vibration of an aeroelastic model (AM) have been systematically carried out. More specifically, the aerodynamic feedback effects on the structural responses, on the mean and root-mean-square wind pressures, on the power spectra and coherence functions of wind pressures at selected locations, and on the aerodynamic forces were investigated. The results indicated the vibration in the lock-in range made the shedding vortex more coherent and better organized, and hence presented unfavorable wind-induced effects on the structure. Whereas the vibration in the non-lock-in range generally showed insignificant effects on the flow structures surrounding the square cylinder.

• Biomolecules & Therapeutics
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• v.4 no.2
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• pp.205-207
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• 1996

Clonidine, an antihypertensive drug, stimulates postsynaptic alpha-2 adrenergic receptors in the central nervous system and lowers arterial pressure through the effects on both cardiac output and peripheral resistance. However, many patients experience that sedation and xerostomia occur upon oral administration of clonidine. These side effects are due to high plasma peak concentration and can be avoided when clonidine is given transdermally. In this study, we tested the antihypertensive effects of trandermal administration of clonidine patch on spontaneously hypertensive rat (SHR) which is a model animal for human essential hypertension. Forty eight SHR (male) were divided into six groups according to the dose levels, respectively. After transdermal administration of clonidine patch of each dose, systolic blood pressure and heart rate were measured. Clonidine patch produced maximal antihypertensive and bradycardiac effects 48 hrs after administration and antihypertensive effects showed dose-dependency. We suggest that antihypertensive effects of clonidine patch are similar to those of orally given clonidine and clonidine patch can be used instead of clonidine tablet.

• Magazine of the Korean Society of Agricultural Engineers
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• v.15 no.2
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• pp.2980-3001
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• 1973

Nozzle is a part of sprayer and is consists of several elements; swirl plate, vortexchamber, cap and body. The travelling distance of sprayed particles is important in the wide reach nozzle. The factors to influence the travelling distance of the sprayed particles may be the helical angle of swirl plate, the distance of vortex hamber, the slope and the size of cap hole. The study was conducted to examine the effects of these factors on the travelling distance. The results of this study are summarized as follows; 1) There was higher positive correlation(+0.96) between the maximum travelling distance for which amount of sprayed particles was 5cc/cm min. and centro-position of the travelling distance. 2) There was a higher positive correlation(+0.85) between total discharge of sprayed particles and the centro-position of the travelling distance. 3) Main effects and interaction effects of helical angle, pressure, vortex chamber distance and cap slope were significantly affected the travelling distance of sprayed particles. 4) Main effects of helical angle, pressure and cap slope were especially highly significant to influence the travelling disance. 5) Helical angle, pressure, vortex chamber distance and cap slope influenced spraying forward velocity of dise hole, among which cap slope and pressure of nozzle was the most important factors. 6) Effect of change of helical angle on the travelling distance of sprayed particles, was generally a quadratic, the least value of the distance being showed about $45^{\circ}$ and the largest at about $15^{\circ}\;and\;55^{\circ}$, the decreasing rate of the change between $15^{\circ};and\;25^{\circ}$ was very small. 7) Effect of change of pressure on the travelling distance sprayed particles was generally a linear, the increasing rate of the charge was about 1.68, which was the most effective compared to the change of the other factors. 8) Effect of change of vortex chamber distance on the spraying distance was also generally a linear, the increasing rate being about 0.16, which was the least effective. 9) Effect of change of cap slope on the travelling distance was also generally a linear, the increasing rate was about 0.61 and its effect was about medium.

• Journal of Pharmacopuncture
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• v.18 no.2
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• pp.33-41
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• 2015

Objectives: The present study evaluated the effects of sa-am acupuncture (SAA) simpo-jeongkyeok (SPJK) treatment on the blood pressure (BP), pulse rate (PR), and body temperature (BT) of patients with hwa byung (HB). Methods: This patient assessor blind, randomized, placebo controlled trial included 50 volunteers, divided randomly into two groups. The treatment group underwent SPJK (PC9, LR1, PC3, KI10) while the control (sham) group received minimal needle insertion at non acupoints. The BP in both arms, PR, and BT at several acupoints were measured before and after treatment at the $1^{st}$, $2^{nd}$, $3^{rd}$, and $4^{th}$ visits and before treatment at the follow-up visit. We analyzed data by using the repeated measured analysis of variance (RM ANOVA), Mann-Whitney U, and wilcoxon signed rank tests; differences at P < 0.05 were considered significant. Results: No significant differences in the systolic blood pressure (SBP), diastolic blood pressure (DBP) and PR between the treatment and control group were observed at each visit. However, the decrease in the SBP for the treatment group before and after each visit was significantly higher than it was in the control group. The SBP in both arms in the treatment group was decreased between visits 1 and 2, 1 and 3, 1 and 4, and 1 and follow-up. The DBP in both arms and in the right arm between visits 1 and 3 in the treatment group showed decreases. A minimal BT increase for treatment at CV06 and CV12 and a minimal BT decrease for treatment at CV17 and (Ex) Yintang were found. Patients in the treatment group who visited more frequently experienced a greater decrease in the PR, but that effect was not maintained. Conclusion: The results suggest that SAA SPJK treatment has instant positive effects on the BP, PR, and BT in patients with HB, but the effects on the BP and PR are not maintained.

• Nuclear Engineering and Technology
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• v.53 no.8
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• pp.2616-2628
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• 2021

The results of effective irradiation swelling in a wide range of burnup levels are numerically obtained for an inert matrix fuel, which are verified with DART model. The fission gas swelling of fuel particles is calculated with a mechanistic model, which depends on the external hydrostatic pressure. Additionally, irradiation and thermal creep effects are included in the inert matrix. The effects of matrix creep strains, external hydrostatic pressure and temperature on the effective irradiation swelling are investigated. The research results indicate that (1) the above effects are coupled with each other; (2) the matrix creep effects at high temperatures should be involved; and (3) ranged from 0 to 300 MPa, a remarkable dependence of external hydrostatic pressure can be found. Furthermore, an explicit multi-variable mathematic model is established for the effective irradiation swelling, as a function of particle volume fraction, temperature, external hydrostatic pressure and fuel particle fission density, which can well reproduce the finite element results. The mathematic model for the current volume fraction of fuel particles can help establish other effective performance models.

• Journal of Preventive Medicine and Public Health
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• v.32 no.3
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• pp.415-420
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• 1999

Objectives: We investigated the effects of changes in obesity and life style factors, such as cigarette smoking, alcohol drinking, and exercise, on the changes in blood pressure and serum cholesterol among Korean men. Methods: This study included 7,205 healthy male employees in the steel manufacturing industry. Each subject underwent health examination in 1994 and was re-examined in 1997. The study subjects were classified into four categories, according to changes in body mass index (BMI) (loss; stable; mild gain: severe gain), cigarette smoking (quitter; nor-smoker; smoker continued; smoker started), alcohol drinking (quitter; non-drinker; drinker continued; drinker started) and exercise (more exercise; continuous regular exercise; continuous irregular or no exercise; less exercise), respectively. We evaluated the relationship between the categories of change in those independent variables and the changes in blood pressure and serum cholesterol, adjusted for BMI in 1994 and age by analysis of variance. Results: The change in systolic blood pressure was positively associated with the changes in BMI (p<0.001) and drinking (p=0,001), but negatively with smoking (p=0,004), compared to the first category of each independent variables. The systolic blood pressure was significantly less increased in the continuous smoking group than quitter or hon-smoker. The changes in diastolic blood pressure and serum cholesterol appeared to have statistically significant linear relationships only with the change in BMI. The change in exercise showed a marginal significance with diastolic blood pressure (p=0.088). Conclusions: These prospective data emphasize the importance of obesity as a determinant of the changes in blood pressure and serum cholesterol. In addition, the changes in smoking and drinking habits can affect systolic blood pressure.

• Fibers and Polymers
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• v.6 no.4
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• pp.322-331
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• 2005

Graduated compression stockings (GCS) have been widely used for the prophylaxis and treatment of venous diseases. Their gradient pressure function largely related to their fabric structure and material properties. By combing fabric physical testing and wear trials, this study investigated the GCSs fabric structure and material properties at different locations along the stocking hoses, and quantitatively analyzed the effects of fabrics on skin pressure longitudinal and transverse distributions. We concluded that, Structural characteristics and material properties of stocking fabrics were not uniform along the hoses, but a gradual variation from ankle to thigh regions, which significantly influenced the corresponding skin pressure gradient distributions; Tensile (WT, EM) and shearing properties (G) generated most significant differences among ankle, knee and thigh regions along the stocking hose, which significantly influenced the skin pressure lognitudinal gradient distribution. More material indices generating significant gradual changes occurred in the fabric wale direction along stocking hose, meaning that materials properties in wale direction would exert more important impact on the skin pressure gradient performances. And, the greater tensibility and smoother surface of fabric in wale direction would contribute to put stocking on and off, and facilitate wearers' leg extension-flexion movements. The indices of WT and EM of stocking fabrics in series A have strong linear correlations with skin pressure lognitudinal distribution, which largely related to their better performances in gradual changes of material properties. Skin pressure applied by fabric with same material properties produced pronounced differences among four different directions around certain cross-sections of human leg, especially at the ankle region; and, the skin pressure magnitudes at ankle region were more easily influenced by the materials properties, which were considered to be largely related to the anatomic structure of human leg.

• The Korean Journal of Physiology
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• v.4 no.1
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• pp.47-54
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• 1970

The effects of excess salt ingestion or/and a prolonged electrical stimulation of the hypothalamus on the arterial blood pressure were studied in cats. The average mean arterial pressure determined in 12 control animals were $112.2{\pm}2.6\;mmHg$. In 15 animals in which 2% NaCl solution (2g/Kg of body wegight/day) was given for 20 days, average mean arterial pressure elevated to $147.7{\pm}6.1\;mmHg$. It was also found in four of them that salt-induced high blood pressure started to decline when salt solution was replaced by tap water. On the other hand, No change in average mean arterial pressure was observed in 10 animals, whose hypothalamus had been electrically stimulated for 28 days. In 11 animals in which the hypothalamus was stimulated with simultaneous excess salt ingestion for 20 days, there was a marked elevation in average mean arterial pressure which, however, does not significantly differ from that observed in excess salt ingested group. From the results obtained from the present experiment, it is concluded that 1) the hypertension is induced by an excess salt ingestion in cats, 2) the mean arterial pressure of cats is not affected at least by an increment of sympathetic tone for 4 weeks resulting from the electrical stimulation of posterior area of the hypothalamus, 3) in sodium·induced high blood pressure cats, four weeks of increment in sympathetic tone by the hypothalamic stimulation does not further elevate mean arterial pressure.

• Korean Journal of Applied Biomechanics
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• v.28 no.1
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• pp.45-54
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• 2018

Objective: The purpose of this study was to investigate the effect of foot strengthening exercise program and functional insoles on joint angle and plantar pressure in elderly women. Thirteen elderly women who were enrolled in a university senior citizens academy of a metropolitan city in 2017 were divided into two groups: exercise group with functional insole (n=7) and exercise group without functional insole (n=6). Method: Three-dimensional motion analysis and Pedar-X were performed to compute the joint angle and the foot plantar pressure, respectively. Two-way repeated measure ANOVA was conducted to compare dependent variables within and between groups. The significance level was set at ${\alpha}=.05$. Results: The range of motion (ROM) of the ankle, knee, and hip joints in the exercise group with functional insole increased significantly more than the exercise group without functional insole. In both the experimental group and the comparison group, the maximum foot plantar pressure and the mean foot plantar pressure were decreased, but the comparison group without functional insole showed more decrease. Since the experimental group demonstrated greater pressure than the comparison group in the contact area (forefoot, midfoot), it was distributed over a greater area. Conclusion: The results of this study suggest that participation in foot strengthening exercises and using a functional insole has more positive effects than foot strengthening exercises alone on the joint angle and plantar pressure in elderly women. Increased foot plantar pressure led to an increased contact area (forefoot, midfoot) for distribution of the foot plantar pressure, but the effect of reducing the maximum and average plantar pressures was incomplete. However, wearing functional insoles along with exercise, could help in improving the stability of the joints, by increasing the range of motion, and could help the elderly in movement of the muscles more effectively, leading to an improvement in gait function.