• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권1호
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• pp.41-49
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• 2019

Recent studies on pediatric inflammatory bowel disease (IBD) have revealed that early-onset IBD has distinct phenotypic differences compared with adult-onset IBD. In particular, very early-onset IBD (VEO-IBD) differs in many aspects, including the disease type, location of the lesions, disease behavior, and genetically attributable risks. Several genetic defects that disturb intestinal epithelial barrier function or affect immune function have been noted in these patients from the young age groups. In incidence of pediatric IBD in Korea has been increasing since the early 2000s. Neonatal or infantile-onset IBD develops in less than 1% of pediatric patients. Children with "neonatal IBD" or "infantile-onset IBD" have higher rates of affected first-degree relatives, severe disease course, and a high rate of resistance to immunosuppressive treatment. The suspicion of a monogenic cause of VEO-IBD was first confirmed by the discovery of mutations in the genes encoding the interleukin 10 (IL-10) receptors that cause impaired IL-10 signaling. Patients with such mutations typically presented with perianal fistulae, shows a poor response to medical management, and require early surgical interventions in the first year of life. To date, 60 monogenic defects have been identified in children with IBD-like phenotypes. The majority of monogenic defects presents before 6 years of age, and many present before 1 year of age. Next generation sequencing could become an important diagnostic tool in children with suspected genetic defects especially in children with VEO-IBD with severe disease phenotypes. VEO-IBD is a phenotypically and genetically distinct disease entity from adult-onset or older pediatric IBD.

• 현장농수산연구지
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• 제13권1호
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• pp.103-114
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• 2011

본 연구는 설문조사를 통하여 한우 송아지의 이유월령이 거세한우의 출하체중 및 송아지 폐사에 미치는 영향을 조사하고자 수행되었다. 설문은 방문을 통하여 진행되었고, 조사된 총 농가수는 862농가로서, 가임암소사육규모별 조사 농가수는 10~19두 188호, 20~49 364호, 50~99두 227호, 100두 이상 83호로 나타났다. 이유시기는 3개월령 농가의 비율이 40.4%로 가장 높게 나타났으며, 각 사육규모별로도 3개월령이 가장 높은 비율을 차지하였다. 이유월령 3개월을 초과하는 각 사육규모별 농가의 비율은 10~19두 규모가 53.5%로서 가장 높게 나타났으며, 20~49두 규모 37.5%, 50~59두 규모 43.7%, 100두 이상 규모는 39.0%로 조사되었다. 조사 농가의 사육규모는 거세한우 출하개월령, 출하시 생체중 및 도체중에 영향을 미치지 않았다. 그러나 이유월령의 증가와 도체중은 유의적으로 음(-)의 상관관계를 가지고 있는 것으로 조사되었다. 따라서 도체중은 이유월령이 짧을수록 증가하는 것으로 나타났다. 조사 농가의 평균 한우 송아지 폐사율은 5.6%로 나타났으며, 사육규모는 한우 송아지의 폐사율에 영향을 미치지 않았다. 반면에 이유월령과 한우 송아지 폐사율 및 폐사 원인인 설사 비율은 유의적으로 양(+)의 상관관계를 가지고 있는 것으로 조사되었다. 따라서 한우 송아지 폐사율은 이유월령이 짧을수록 감소하는 것으로 나타났다. 본 설문조사의 결과, 이유시기의 단축은 거세한우의 도체중 증가와 송아지 폐사율 감소의 효과로 한우 번식우 농가의 수익성을 향상시킬 수 있음을 보여주고 있다.

• 대한물리치료과학회지
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• 제6권3호
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• pp.91-106
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• 1999

In the present day. there has been concern to improve the environment which included with no age limit and disability. But many buildings differentiate people with disabilities from people with non-disabilities and it is problem that infringe upon impartiality. Because people have a variety of age, disability, health-condition and so forth, they do not want to a target of special relation. As an alternative plan, it is necessary to introduce the universal design which is able to use for every body and all-round environment. Based on universal design, this paper reports what can be apply from building service from building and proposes basic of the spatial building service to improve the quality of life of people.

• Journal of Astronomy and Space Sciences
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• 제13권1호
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• pp.55-62
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• 1996

We present UBV CCD photomety of the metal-poor globular cluster M30. The data were obtained using the 40 inch telescope at Mt. Stromlo and Siding Spring Observatory (MSSSO). We used DAOPHOT CCD reduction package in order to obtain Color-Magnitude Diagram (CMD). We have derived some fundametal parameters of the globular cluster such as metal abundance ([Fe/H]), helium abundance (Y), and distance modulus (m-M) from the CMD. The derived parameters were [Fe/H]=-2.50, Y=0.28, and (m-M)=14.64. From the latter, the distance of 8.3kpc is obtained. Despite the photometric uncertainty near the main-sequence turnoff, we estimate the age of M30 to be 1.6${\pm}$3 Gyrs from the Revised Yale Isocyrones. If [O/Fe]=+0.4, this age will be reduced to 14.2${\pm}$3 Gyrs.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제17권2호
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• pp.159-162
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• 1995

Five patients underwent surgery to treat velopharyngeal incompetence with an inferiorly based pharyngeal flap, and were evaluated postoperatively with a nasoendoscopy. In all patients, velopharyngeal closure occurred during speech of fricative sounds and swallowing. During speech of closed vowel sounds, patients younger than 10 years of age, compared with patients more than 20 years of age, demonstrated a grater improvement in velopharyngeal closure postoperatively. The present study supported the concept that an early pharyngoplasty should be made to obtain improved speech and articulation.

• Safety and Health at Work
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• 제6권2호
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• pp.151-155
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• 2015

The study was designed to identify any trends of injury type as it relates to the age and trade of construction workers. The participants for this study included any individual who, while working on a heavy and highway construction project in the Midwestern United States, sustained an injury during the specified time frame of when the data were collected. During this period, 143 injury reports were collected. The four trade/occupation groups with the highest injury rates were laborers, carpenters, iron workers, and operators. Data pertaining to injuries sustained by body part in each age group showed that younger workers generally suffered from finger/hand/wrist injuries due to cuts/lacerations and contusion, whereas older workers had increased sprains/strains injuries to the ankle/foot/toes, knees/lower legs, and multiple body parts caused by falls from a higher level or overexertion. Understanding these trade-related tasks can help present a more accurate depiction of the incident and identify trends and intervention methods to meet the needs of the aging workforce in the industry.

• 아동학회지
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• 제9권1호
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• pp.63-80
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• 1988

The main purpose of this study was to investigate the relationships of children's creativity to field independence-dependence cognitive style and demographic variables at age 5. The subjects for the present study were 86 five-year-old boys and girls selected from two kindergartens in Seoul and their parents, who replied to the questionnaire about demographic variables. Children were tested in groups, with the Torrance tests of Creative Thinking-Figural, and individually with the Preschool Embedded Figures Test. The data were analyzed by one way ANOVA, t-test, and Pearson's product-moment correlations. Children's fluency and originality in creativity showed significant positive correlations with field dependent-independent cognitive style. There were no significant differences in creativity according to sex. There were significant differences in field dependent-independent cognitive style according to sex. The score of field independent cognitive style of boys were significantly higher than those of girls. Children's creativity showed low correlations with demographic variables.

• 아동학회지
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• 제11권1호
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• pp.45-57
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• 1990

The purpose of the present study was to investigate the age-related differences in recall and to assess effects of presentation modality, encoding condition and cue modality on recall in terms of encoding specificity principles and dual-coding theory. Eighty children in each of 3grades(first, third and fifth) were presented a 30-item set of pictures or words on cars for recall in a study-test procedure. The experiment was designed as a 3(age) x 2(presentation modality:picture or word) x 2(encoding condition:random or category) x 2(cue modality:picuture or word) factorial design. Statistical analyses were with four-way ANOVA and $Scheff\acute{e}$ test. It was concluded from these results that when the stimulus was presented by pictures, encoded by category and the cues were also presented by pictures, recall increased in all ages. These results were interpreted in terms of encoding specificity principles and dual-coding theory.

• Archives of Plastic Surgery
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• 제43권6호
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• pp.582-585
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• 2016

It is uncommon for a palatal fistula to be detected in individuals who have not undergone surgery, and only sporadic cases have been reported. It is even more difficult to find cases of acquired palatal fistula in patients with submucous or incomplete cleft palate. Herein, we present 2 rare cases of this phenomenon. Case 1 was a patient with submucous cleft palate who acquired a palatal fistula after suffering from oral candidiasis at the age of 5 months. Case 2 was a patient with incomplete cleft palate who spontaneously, without trauma or infection, presented with a palatal fistula at the age of 9 months.

• 천문학회지
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• 제38권2호
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• pp.145-148
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• 2005

We present a photometric study of galaxies in the central regions of six nearby galaxy clusters at redshift z=0.0231${\~}$0.0951. We have derived BVI photometry of the galaxies from the CCD images obtained at the Bohyunsan Optical Astronomical Observatory (BOAO) in Korea, and JHKs photometry of the bright galaxies from the 2MASS extended source catalog. Comparing the galaxy photometry results with the simple stellar population model of Bruzual & Charlot (2003) in the optical & NIR color-color diagrams, we have estimated the ages and metallicities of early type galaxies. We have found that the observed galaxies had recent star-formation mostly 5 ${\~}$ 7 Gyrs ago but the spread in age estimation is rather large. The average metallicities are [Fe/H]=0.l${\~}$0.5 dex. These results support the hypothesis that large early type galaxies in clusters are formed via hierarchical merging of smaller galaxies.