• Imaging Science in Dentistry
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• 제43권4호
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• pp.273-281
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• 2013

Purpose: This study was performed to evaluate the general anatomy and morphology of the nasopalatine canal using cone-beam computed tomography (CBCT) and to determine the human anatomic variability of the nasopalatine canal in relation to age and gender. Materials and Methods: The study included 100 subjects aged between 20 and 86 years who were divided into the following 3 groups: 1) 20-34 years old; 2) 35-49 years old; 3) ${\geq}50$ years old. The subjects were equally distributed between the genders. CBCT was performed using a standard exposure and patient positioning protocol. The data of the CBCT images were sliced in three dimensions. Image planes on the three axes (X, Y, and Z) were sequentially analyzed for the location, morphology and dimensions of the nasopalatine canal by two independent observers. The correlation of age and gender with all the variables was evaluated. Results: The present study did not reveal statistically significant differences in the number of openings at the nasal fossa; diameter of the nasal fossa openings; diameter of the incisive fossa; shape, curvature, and angulation of the canal as viewed in the sagittal sections; antero-posterior dimensions and length of the canal in the sagittal sections; or the level of division of the canal in the coronal plane by age. However, males and females showed significant differences in the length of the canal in the sagittal sections and level of the division of the canal in the coronal plane. Conclusion: The present study highlighted important variability observed in the anatomy and morphology of the nasopalatine canal.

• Clinical and Experimental Pediatrics
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• 제55권12호
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• pp.481-486
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• 2012

Purpose: Precocious puberty is defined as breast development before the age of 8 years in girls. The present study aimed to reveal the diagnosis of Korean girls referred for precocious puberty and to compare the constitutional and endocrinological features among diagnosis groups. Methods: The present study used a retrospective chart review of 988 Korean girls who had visited a pediatric endocrinology clinic from 2006 to 2010 for the evaluation of precocious puberty. Study groups comprised fast puberty, true precocious puberty (PP), pseudo PP, premature thelarche, and control. We determined the height standard deviation score (HSDS), weight standard deviation score (WSDS), and body mass index standard deviation score (BMISDS) of each group using the published 2007 Korean growth charts. Hormone tests were performed at our outpatient clinic. Results: The PP groups comprised fast puberty (67%), premature thelarche (17%), true PP (15%), and pseudo PP (1%). Advanced bone age and levels of estradiol, basal luteinizing hormone (LH), and peak LH after gonadotropin-releasing hormone stimulation testing were significantly high in the fast puberty and true PP groups compared with the control group. HSDS, WSDS, and BMISDS were significantly higher in the true PP group than in the control group (P<0.05). Conclusion: The frequent causes of PP were found to be fast puberty, true PP, and premature thelarche. Furthermore, BMISDS were significantly elevated in the true PP group. Therefore, we emphasize the need for regular follow-up of girls who are heavier or taller than others in the same age group.

• Journal of Animal Science and Technology
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• 제64권3호
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• pp.500-514
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• 2022

The blood-epididymis barrier (BEB) forms a unique microenvironment that is crucial for the maturation, protection, transport, and storage of spermatozoa in the epididymis. To characterize the function of tight junctions (TJs), which are constitutive components of the BEB, we determined the expression and localization of TJ proteins such as zonula occludens (ZO)-1, 2, and 3, occludin, and claudin3 (Cldn3) during postnatal development in the goat epididymis. To assess the expression patterns of TJ proteins in immature (3 months of age) and mature (14 months of age) goat epididymides, two different experimental methods were used including immunofluorescence labeling and western blotting. We show that, ZO-1, 2, and 3, and occludin, were strictly expressed and localized to the TJs of the goat epididymis, whereas Cldn3 was present in basolateral membranes as well as TJs. All TJ proteins examined were more highly expressed in the immature epididymis compared to levels in mature tissue. In conclusion, our study indicates that at least five TJ proteins, namely ZO-1, ZO-2, ZO-3, occludin, and Cldn3, are present in TJs, and the expression strength and pattern of TJ proteins tend to be age dependent in the goat epididymis. Together, these data suggest that the distinct expression patterns of TJ proteins are essential for regulating components of the luminal contents in the epididymal epithelium and for forming adequate luminal conditions that are necessary for the maturation, protection, transport, and storage of spermatozoa in the goat epididymis.

• 대한후두음성언어의학회지
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• 제12권1호
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• pp.55-60
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• 2001

Background and Objectives : Syllable Maximum Repetition Rate(MRR) is ability to repeat rapidly the articulators and is assessed for oromechanism function as one of the MPT. MRR is measured by rate(counts/sec), also simultaneously considered accuracy and consistency. The objective of the present was to examine stimuli effects and age and sex differences for MRR. Materials and Method : This study was participated 60 normal males and females(1 : 1) who were divided into two groups young(<40 years old) and old($\geq$40 years old). Stimuli were $/{P^=}a/,/{t^=}a/,/{k^=}a/,/{P^h}a/,/{t^h}a/,/{k^h}a/,/{P^=}{at^=}{ak^=}a/$ for, manner(tense and aspirated) of articulation, $/{p^h}{at^h}{ak^h}a/,/{t^h}{ap^h}{ak^h}a/$ for the effect of the order of syllable, glide /u-i/ for coordination of lip and tongue, interrupted vowel /i/ for laryngeal function. Results : There were little differences in two age groups and sex and manner of articulation for MRR tasks. The fastest average MRR of the single syllable included in this study was $/{t^=}a/$. significant differences existed between MRR for ${p^h}{at^h}{ak^h}a/ and /{t^h}{ap^h}{ak^h}a/$, which suggested that MRR was affected by the order of the syllables. MRR for interrupted vowel /i/ was about 2 counts/sec slower than average rate of 1 syllables. Conclusion : From these results, the order of the syllables was a crucial variable in MRR. rather than age or sex. There were no difference age, sex and manner of rate. The interrupted vowel repetition rate was slightly slow used and can provide basic information to assess the speech mechanism and can be useful to develop effective stimuli to differentiate the disordered group from normal.

• 가정과삶의질연구
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• 제34권4호
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• pp.1-19
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• 2016

The present study aimed at investigating the relations between the amount of child care experienced in the first three years of life and socioemotional development of children at age 4 indicated by problem behaviors and peer competence. Using the longitudinal data of the Panel Study of Korean Children(PSKC), the information of 1,699 children were analyzed. The results indicated that any child care experience, hours in child care, full-time child care and early entry to child care were significantly related to children's externalizing behavior problem and play disruption at age 4. Some significant relations were detected between child care experience and better peer competence as well. Interestingly, the patterns of relations were different for boys and girls. Being in child care, a greater amount of child care and early entry to child care tended to be related to externalizing problem behaviors of boys and whereas they were more related to peer competence of girls indicated by play interaction, play disruption and play disconnection. Child care hours at age 3 were relative stronger predictors of children's development compared to those at age 1 or at age 2. The findings imply that the amount of child care during the first 3 years of life does not have strong harmful effects on preschoolers' socioemotional development and that there are differences in the effects of child care on boys and girls.

• 한국시조학회지:시조학논총
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• 제21집
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• pp.23-46
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• 2004

본고에서는 조선후기 사설시조에 나타난 여가활동의 양상을 분석하여 우리민족의 여가문화의 한 단면을 살펴보고자 하였다. 조선조 사설시조에 나타난 여가활동은 기분전환과 유홍지향, 건강관리와 신체회복, 자기계발과 생활변화 등의 양상으로 주제화되어 작품에 나타나고 있다. 기분전환과 유흥지향의 시조는 소년시절의 여가활동을 주로 표출하고 있으며, 건강관리와 신체회복의 시조는 노년시절의 여가활동을 주로 표출하고 있다. 그리고 자기계발과 사회적응의 시조에는 소년시절과 노년시절의 여가활동이 함께 나타나는 현상을 보여주고 있다. 이처럼 사설시조에 나타난 여가의 양상은 크게 소년시절의 여가활동과 노년시절의 여가활동으로 나누어질 수 있다. 그런데 소년시절의 여가활동은 건전한 여가와 위험한 여가가 함께 어우러져 있으나, 노년시절의 여가활동은 건전한 여가가 대부분이라 할 수 있다. 사설시조에 나타난 가장 완전한 여가활동으로는 개인의 기분전환, 신체회복, 자기계발, 창조정신 등의 내용이 함께 어울러져있어야 한다고 할 수 있다. 주5일 근무제가 시행되는 2004년, 현재를 살아가는 우리들은 옛 시조에 나타난 여유와 느림의 미학에 바탕을 둔 선조들의 여가활동을 음미해봄으로써 심신이 건강한 맛과 멋의 여가활동을 함께 즐겨야 할 것이다.

• Journal of Korean Neurosurgical Society
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• 제59권6호
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• pp.590-596
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• 2016

Objective : Rheumatoid arthritis (RA) is a systemic disease that can affect the cervical spine, especially the atlantoaxial region. The present study evaluated the risk factors for atlantoaxial subluxation (AAS) development and progression in patients who have undergone surgical treatment. Methods : We retrospectively analyzed the data of 62 patients with RA and surgically treated AAS between 2002 and 2015. Additionally, we identified 62 patients as controls using propensity score matching of sex and age among 12667 RA patients from a rheumatology registry between 2007 and 2015. We extracted patient data, including sex, age at diagnosis, age at surgery, disease duration, radiographic hand joint changes, and history of methotrexate use, and laboratory data, including presence of rheumatoid factor and the C-reactive protein (CRP) level. Results : The mean patient age at diagnosis was 38.0 years. The mean time interval between RA diagnosis and AAS surgery was $13.6{\pm}7.0$ years. The risk factors for surgically treated AAS development were the serum CRP level (p=0.005) and radiographic hand joint erosion (p=0.009). The risk factors for AAS progression were a short time interval between RA diagnosis and radiographic hand joint erosion (p<0.001) and young age at RA diagnosis (p=0.04). Conclusion : The CRP level at RA diagnosis and a short time interval between RA diagnosis and radiographic hand joint erosion might be risk factors for surgically treated AAS development in RA patients. Additionally, a short time interval between RA diagnosis and radiographic hand joint erosion and young age at RA diagnosis might be risk factors for AAS progression.

• 디지털융복합연구
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• 제12권6호
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• pp.579-586
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• 2014

본 연구에서는 장애인고용패널조사(Panel Survey of Employment for the Disable) 4차 자료를 이용하여, 40세 이상의 장애인 3,396명을 대상으로 경제적 노후준비가 삶의 질에 미치는 영향을 파악하는데 목적이 있었다. 연구결과 첫째, 노후준비를 하고 있는 장애인이 삶의 만족도가 노후준비를 하지 않고 있는 장애인의 삶의 만족도보다 높았다. 둘째, 노후준비를 하고 있는 장애인은 국가운영 공적연금으로 노후준비를 하고 있는 비율이 가장 높았으며, 경제적 노후준비는 충분하지 않다고 인지하는 것으로 나타났다. 마지막으로, 장애인의 노후준비에 따른 삶의 만족도 영향요인을 파악하기 위해 위계적 회귀분석을 실시한 결과, 노후준비가 충분할수록 삶의 만족도가 높은 것으로 나타났다.

• 천문학회보
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• 제37권1호
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• pp.31.2-31.2
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• 2012

We present the Yonsei Evolutionary Population Synthesis (YEPS) models for spectroscopic and photometric evolutions of simple and composite stellar populations. The models are based on the most up-to-date Yonsei-Yale stellar evolutionary tracks and BaSel 3.1 flux libraries, and provide integrated spectroscopic quantities of Lick/IDS system including high-order Balmer absorption-lines. Special care has been taken to incorporate the systematic variation of horizontal branch (HB) morphology as functions of metallicity, age, alpha-element mixture, and helium abundance of simple stellar populations. Our models for normal-helium stellar populations indicate that the realistic modeling of HB and alpha-element brings about 5 Gyr and 0.1 dex differences in age and metallicity estimations, respectively, compared to those without these effects. The HB effect does not depend on the specific choice of stellar libraries and alpha-element enhancements, and this effect is non-negligible even in the metal sensitive absorption indices, such as Mg2 and Mg b. Comparison of the models to observations reveals that the HB and alpha-element effects are critical in understanding otherwise inexplicable phenomena found in globular cluster systems in the Milky Way and nearby galaxies, including the observed bimodality of the line strengths of globular clusters in massive galaxies. In addition, we found that helium-enhanced stellar populations, which are the major sources of extreme HB stars, bring about increased FUV, NUV fluxes, and thus the model colors of those filters become extremely blue. Age dating based on the YEPS model with normal-helium stellar populations reveals that the evidence for 'downsizing' of elliptical galaxies is found not only in the local field but also in Coma cluster, and that the mean age of elliptical galaxies in Coma cluster is about 1.4 Gyr younger than the mean age of those in the local field. We also find that our models with helium-enhanced subpopulations can naturally reproduce the strong UV-upturns observed in giant elliptical galaxies assuming an age similar to that of old GCs in the Milky Way.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6245-6250
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• 2012

Background: With increase in life expectancy, adoption of newer lifestyles and screening using prostate specific antigen (PSA), the incidence of prostate cancer is on rise. Globally prostate cancer is the second most frequently diagnosed cancer and sixth leading cause of cancer death in men. The present communication makes an attempt to analyze the time trends in incidence for different age groups of the Indian population reported in different Indian registries using relative difference and regression approaches. Materials and Methods: The data published in Cancer Incidence in Five Continents for various Indian registries for different periods and/or publications by the individual registries served as the source materials. Trends were estimated by computing the mean annual percentage change (MAPC) in the incidence rates using the relative difference between two time periods (latest and oldest) and also by estimation of annual percentage change (EAPC) by the Poisson regression model. Results: Age adjusted incidence rates (AAR) of prostate cancer for the period 2005-2008 ranged from 0.8 (Manipur state excluding Imphal west) to 10.9 (Delhi) per $10^5$ person-years. Age specific incidence rates (ASIR) increased in all PBCRs especially after 55 years showing a peak incidence at +65 years clearly indicating that prostate cancer is a cancer of the elderly. MAPC in crude incidence rate(CR) ranged from 0.14 (Ahmedabad) to 8.6 (Chennai). Chennai also recorded the highest MAPC of 5.66 in ASIR in the age group of 65+. Estimated annual percentage change (EAPC) in the AAR ranged from 0.8 to 5.8 among the three registries. Increase in trend was seen in the 55-64 year age group cohort in many registries and in the 35-44 age group in Metropolitan cities such as Delhi and Mumbai. Conclusions: Several Indian registries have revealed an increasing trend in the incidence of prostate cancer and the mean annual percentage change has ranged from 0.14-8.6.