• Clinical and Experimental Pediatrics
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• 제54권5호
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• pp.201-206
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• 2011

Purpose: Westernized eating habits have been associated with earlyage menstruation, which increases the incidence of dysmenorrhea and premenstrual syndrome among adolescent girls. We therefore surveyed changes in menarche timing and the general menstrual characteristics of adolescent girls in Seoul, Korea. Methods: We surveyed 538 teenage girls who visited our hospital between July and November 2007. Items explored included age at menarche, general menstrual characteristics, occurrence of premenstrual syndrome and treatment thereof, and an association between present dysmenorrhea and a family history of the condition. Results: Average age at menarche was 12.6 years, with 29% (n=156) subjects beginning menstruation at age 12 years. The prevalence of dysmenorrhea was 82% (n=435). The main symptoms were abdominal (53.2%) and lower back pain (34.2%), and 15.2% of girls who experienced such symptoms required medication. Present dysmenorrhea, and a family history thereof, were statistically correlated (P<0.05). In addition, 58.8% (n=316) of teenage girls had symptoms of premenstrual syndrome. The most frequent psychological symptoms were fatigue (36.4%) and nervousness (38.7%), whereas the most common physical symptom was menstrual cramps (46.5%). Most subjects (87.6%) tolerated the symptoms of premenstrual syndrome without medication; 11.4% took medicines including painkillers; but only 0.1% of subjects visited a doctor. Conclusion: The average age at menarche in Korean girls was 12.6 years, thus younger than in the past. Most teenage girls experienced dysmenorrhea and premenstrual syndrome, but few consulted a doctor. Organized treatment plans are required to manage menstrual problems in teenage girls.

• Asian-Australasian Journal of Animal Sciences
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• 제14권11호
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• pp.1585-1591
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• 2001

The present study was conducted to evaluate the effect of early feed restriction on growth, fat accumulation and meat composition in unsexed broiler chickens. Five hundred 7-day old unsexed broiler chickens were distributed into ten treatment groups with 5 pens of 10 broilers each group. One group was fed ad libitum as the control group and other nine groups were fed 25% ad libitum for 3, 6 or 9 days, 50% ad libitum for 3, 6 or 9 days, and 75% ad libitum for 3, 6 or 9 days, respectively. Thereafter, they were fed ad libitum to 56 days of age. The present results showed that broilers showed compensatory growth when they were restrict-refed. Feed conversion ratio was significantly lower in broilers fed 25% ad libitum for 9 days (p<0.05). Triglyceride concentration of serum was significantly lower in restricted unsexed broilers (p <0.01), whereas cholesterol concentration was not significantly different. Abdominal fat was significantly lower in broilers fed 25% ad libitum for 9 days, 50% ad libitum for 3 days and 75% ad libitum for 6 or 9 days (p<0.05). Moisture and protein contents of meats were not significantly affected. Ash content of meat was significantly higher in restricted broilers. Fat content of meat was lower in broilers fed 25% ad libitum for 9 days, 75% ad libitum for 3 to 9 days. In conclusion, broilers showed compensatory growth when they were restrict-refed at an early age. In order to achieve the success of early feed restriction (namely reduce fat accumulation and improve feed conversion ratio with comparable body weight at market age), unsexed broilers should be fed at level of 25 ad libi=tum for 9 days starting at 7 days of age.

• Journal of the Korean Home Economics Association
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• 제43권12호
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• pp.153-163
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• 2005

The purposes of this study were to investigate the differences of appearance behavior and ego integrity of elderly women according to demographic variables, and health, and to examine how the ego integrity of elderly women was influenced by appearance behavior, health, and demographic variables. The subjects were 117 elderly women(aged 60 to 70) in Jinju, Korea who were interviewed face-to face with a survey questionnaire. The results of the study were as follows. There were significant differences in appearance adornment and ego integrity (wise living and attitude toward life) according to age. After controlling for age, there were significant differences in appearance interest, makeup, and ego integrity according to education. There was a significant difference in ego integrity (attitude toward life) according to the presence of a spouse or mate. There were significant differences in appearance interest, makeup, and ego integrity according to health. Health and education had a significant effect on satisfaction with the present living. Health, age(-), and appearance behavior had a significant effect on wise living. Health, age(-), and education had a significant effect on attitude toward life. Education and health had a significant effect on appearance behavior. The present findings indicate that health state and appearance behavior, such as appearance interest and makeup, had a significant effect on the ego integrity of elderly women. On the whole, the ego integrity of elderly women was positively correlated with the level of health state, education, and appearance behavior.

• Economic and Environmental Geology
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• 제4권1호
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• pp.1-9
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• 1971

The "Younger Granites" in Korea were being believed to be late Cretaceous in age and named "Bulkuksa granites" by all previous works until the writer had discovered Jurassic granite in 1963. The present paper is to prove its validity by age dating on these granites which was carried out by Professor Y. Ueda, Tohoku University, Japan. The age of 37 granites samples from various localities ranges from 68 my to 181 my. Of these 10 samples belonged to early Jurassic, 6 samples to mid-Jurassic, 4 samples to late Jurassic, 5 samples to early Cretaceous, and 12 samples to late Cretaceous in age. It is of the writer's opinion that the granites intruded in from early Jurassic to early Cretaceous age belong to Daebo granites and are syntectonic plutons associated with Daebo orogeny, and only those of late Cretaceous age belong to Bulkuksa granites that were associated with Bulkuksa disturbance. Daebo granites are aligned along NE-SW Sinian direction in the middle parts of Korea and crop out in the cores of folded mountains which were formed by Daebo Orogeny, such as Charyong, Noryong, Sobaek, and Dukyu Ranges. On the contrary Bulkuksa granites are restricted in Kyongsang basin and adjacent few localities in distribution and show no alignment. Granites supposedly associated with other disturbances of post-precambrian Have not been found so far in S. Korea. Age dating of granites has revealed that Daebo orogeny might be continuous from Songrim distur bance of late Triassic age. From this viewpoint, it could be assumed that Daedong system of Jurassic age were deposited in separate intermontain basins while Daebo orogeny was active, so that Daedong system in separate localities in Korea could not been correlated in their lithology as well as stratig raphy.

• Journal of Animal Science and Technology
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• 제54권6호
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• pp.443-448
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• 2012

This study was conducted to investigate changes of blood metabolites and enzyme activities at different slaughter ages of Hanwoo cattle. Blood samples were taken from six hundred thirty two steers (24~33 months of age) and one hundred twenty eight bulls (17~24 months of age) by venipuncture from caudal vein immediately prior to slaughter. Glucose concentrations were linearly increased (P<0.001) with increases of the slaughter age in steers, and blood urea nitrogen (BUN) concentrations were linearly decreased (P<0.001) with increases of the slaughter age in steers. Likewise, glucose and albumin concentrations in bulls were linearly decreased (P=0.009 and P<0.001, respectively) with increases of the slaughter age. BUN, cholesterol, triglycerides, and total cholesterol concentrations were linearly increased (P<0.001, 0.018 and 0.002, respectively), and creatinine concentrations were quadratically increased (P=0.009) with increases of the slaughter age. Activity of gamma glutamyltransferase (${\gamma}$-GT) and aspartate aminotransferase (AST) was linearly increased (P<0.001) with increases of the slaughter age in both steers and bulls, whereas alanine aminotransferase (ALT) was not affected by increasing slaughter age. In addition, the concentrations of ${\gamma}$-GT and AST were higher (P<0.05) for bulls than those of steers at 24 months of age. Increased levels of ${\gamma}$-GT and AST indicate impaired liver function; it may be associated with increases of concentrate level which is a concomitant of the extended fattening periods in Hanwoo feeding. In conclusion, the results in the present study may be one of the useful information for diagnosis of the metabolic disorder in Hanwoo cattle.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3951-3955
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• 2015

Background: Colorectal cancer mortality has started to decrease in several developed countries in Asia. The current study aimed to present the long-term trends in colorectal cancer mortality in Korea using joinpoint analysis and age-period-cohort modeling. Materials and Methods: The number of colorectal cancer deaths and the population for each 5-year age group were obtained from Statistics Korea for the period 1984-2013 for adults 30 years and older. Joinpoint regression analysis was conducted to determine changes in trends in age-standardized mortality rates, and age-period-cohort analysis was performed to describe trends in colorectal cancer mortality using the intrinsic estimator method. Results: In men, the age-standardized mortality rate for colorectal cancer increased from 1984 to 2003, and the mortality rates stabilized thereafter, whereas the mortality rate of colorectal cancer in women has decreased since 2004. The age-specific mortality rate of colorectal cancer increased in both men and women over time, whereas decreases in the age-specific mortality rate in younger cohorts were observed. In the age-period-cohort analysis, old age and recent period were associated with higher mortality for both men and women. The birth cohort born after 1919 showed reduced colorectal cancer mortality in both men and women. Conclusions: Our study showed a recent decreasing trend in colorectal cancer mortality in women and a stable trend in men after 2003-2004. These changes in colorectal cancer mortality may be attributed to birth cohort effects.

• Korean Journal of Veterinary Research
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• 제14권1호
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• pp.1-7
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• 1974

Little work has been done on the changes in the blood picture occurring at different ages in cattle. In our country Kim (1963) and Jeong (1965) recorded the blood picture of mature Korean native cattle and, recently, Mun et al. (1974) has recorded the blood picture of Holstein cows. And a comprehensive survey of the blood picture of Korean native cattle has not been made. The object of the present investigation was to make good this deficiency, and to suggest standards for the blood picture of Korean native cattle at frequent intervals from birth to maturity. The cattle were kept under average farming conditions in this country. Observations were made at the following ages: at birth; 1, 2 and 4 days; 1, 2 and 4 weeks; 2,4,6 and 9 months; 1, 2 and 3 years of age. Blood samples were drawn from the jugular vein. Erythrocyte enumerations, concentration of hemoglobin in blood and hematocrit values were made in usual manner. Erythrocyte counts increased from $8{\times}10^6/mm^3$ during the first week to a level of $10{\times}10^6/mm^3$ at 2 months of age, showing steady state untill 6 months of age; it then fell to adult level ($8{\times}10^6/mm^3$) at 9 months of age. Concentration of hemoglobin in blood and hematocrit values were closely related to the changes of erythrocyte counts. The values increased from 10 g/100 ml and 31~35 ml/100 ml during the early life to 11 g/100 ml and 38 ml/100 ml at 2 months of age, showing steady state untill 6 months of age; these then fell to adult level (10 g/100 ml and 31~34 ml/100 ml) at 9 months of age for concentration of hemoglobin in blood and hematocrit values, respectively. Mean corpuscular volume and mean corpuscular hemoglobin showed a common pattern. The values were $42{\sim}43{\mu}m^3$ and 12.4 pg during the early life and fell a little to 6~9 months of age; these then increased to reach adult levels of $43{\mu}m^3$ and 12.6 pg for mean corpuscular volume and mean corpuscular hemoglobin, respectively. Mean corpuscular hemoglobin concentration was little affected with age.

• Journal of Community Nutrition
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• 제1권2호
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• pp.81-87
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• 1999

Body mass index(BMI) is recognized as one of the most useful indexes for adiposity in children and adults. This study was conducted to provide information on BMI distribution by age and sex in Korean children, and to identify sociodemographic factors that affected BMI among children. The study was conducted on 2376 children(boys 1184, girls 1192) living in a middle-size city in Korea. Subjects were selected from the primary schoolchildren in grades 1-6 using the two-stage sampling method. Their mean age was 9.4 years. The percentile of BMI tended to increase as age increased in both sexes. The 85th percentile for boys, aged 6-12 years, was 19.8kg/㎡, and the 95th percentile was 22.5kg/㎡. The 85th percentile for girls, aged 6-12 years, was 18.9kg/㎡, and the 95th percentile was 21.5kg/㎡. Multiple regression analysis was carried out to predict BMI from percent ideal body weight (PIBW), age and sex. After adjusting PIBW and age, BMI for boys was 0.062kg/㎡ lower than that for girls. One year of age increased BIM by 0.55kg/㎡. The prevalence rate of overweight and obesity based on PIBW was 15.8% and 15.0% for boys, and 14.0% and 11.0% for girls, respectively. Demographic factors such as sex, age, and parents' obesity influenced children's BMI. After adjusting for sex, age and parents' BMI, the presence of another children in family, and mother's employment status showed a strong effect on children's BMI. The results suggest an age-sex specific BMI distribution of Korean children. The present study also provides direct evidence of a correlation between early life environmental factors, such as presence of siblings or mother's employment, and BMI level in Korean children.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권4호
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• pp.392-402
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• 2021

Purpose: The present study assessed the role of an amino acid-based formula (AAF) in the growth of infants with cow's milk protein allergy (CMPA). Methods: Non-breastfed, term infants aged 0-6 months with symptoms suggestive of CMPA were recruited from 10 pediatric centers in China. After enrollment, infants were started on AAF for two weeks, followed by an open food challenge (OFC) with cow's milk-based formula (CMF). Infants with confirmed CMPA remained on AAF until 9 months of age, in conjunction with a cow's milk protein-free complementary diet. Body weight, length, and head circumference were measured at enrollment and 9 months of age. Measurements were converted to weight-for-age, length-for-age, and head circumference-for-age Z scores (WAZ, LAZ, HCAZ), based on the World Health Organization growth reference. Results: Of 254 infants (median age 16.1 weeks, 50.9% male), 218 (85.8%) were diagnosed with non-IgE-mediated CMPA, 33 (13.0%) tolerated CMF, and 3 (1.2%) did not complete the OFC. The mean WAZ decreased from 0.119 to -0.029 between birth and enrollment (p=0.067), with significant catch-up growth to 0.178 at 9 months of age (p=0.012) while being fed the AAF. There were no significant changes in LAZ (0.400 vs. 0.552; p=0.214) or HCAZ (-0.356 vs. -0.284; p=0.705) from the time of enrollment to age 9 months, suggesting normal linear and head growth velocity. Conclusion: The amino acid-based study formula, in conjunction with a cow's milk proteinfree complementary diet, supported normal growth till 9 months of age in a cohort of Chinese infants with challenge-confirmed non-IgE-mediated CMPA.

• Development and Reproduction
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• 제24권4호
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• pp.287-296
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• 2020

The absence of functional estrogen receptor α (Esr1) results in an overgrowth of the epididymal fat, as observed in estrogen receptor α knockout (ERαKO) mouse. The present research was aimed to evaluate expression of various molecules associated with adipocyte differentiation and maturation in the epididymal fat of ERαKO mouse at several postnatal ages by using quantitative real-time polymerase chain reaction. The highest transcript levels of all molecules were detected at 12 months of postnatal age, except leptin which the mRNA level was increased at 5 months of age and was unchanged until 12 months of age. The expression levels of CCAAT enhancer binding protein (Cebp) alpha, androgen receptor, and lipoprotein lipase were decreased at 5 months of age but increased at about 8 months of age. The mRNA levels of Cebp gamma and sterol regulatory element binding transcription factor 1 remained steady until 8 months of age. Continuous increases of transcript levels during postnatal period were found in Cebp beta, estrogen receptor (ER) beta, fatty acid binding protein 4, and delta like non-canonical Notch ligand 1. The increases of peroxisome proliferator-activated receptor gamma and adiponectin mRNA levels were detected as early as 8 months of age. The levels of fatty acid synthase and resistin transcript at 5 and 8 months of age were lower than that at 2 months of age. These findings show the aberrant expression patterns of genes related to adipocyte differentiation and maturation in the postnatal epididymal fat pad by the disruption of ER alpha function.