• Title/Summary/Keyword: preparations

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Determination of Taurine in Preparations by Amino Acid Autoanalyzer (아미노산 분석기에 의한 제제중 Taurine의 분리 정량에 관한 연구)

  • 박만기;한달수
    • YAKHAK HOEJI
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    • v.28 no.1
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    • pp.21-23
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    • 1984
  • High performance amino acid analyzing method has been developed for the routine analysis of taurine in preparations. Ion-exchange resin #2619 Hitachi Custom Ion-Exchange Resin, $2.6(I.D.){\times}150$(length)mm was used as column, buffer I, pH 3.3 as mobile phase. The retention time of taurine was 7 minutes. Calibration curve by peak height for standard taurine was linear from 2.5ppm to 25ppm. The reproducibility showed relative standard deviation $\pm$1.9% when analyzed 10 times for standard solution. The samples could be continuously analyzed without regenerating the resin between samples. Five samples were applied to column every 12 min. and then the resin was regenerated for 30 min. during one analyzing cycle time, 90 min. The automatic amino acid analyzer has made it possible to assay multiple samples in a relatively short period of time using the analytical magnetic program card. The high sensitivity and specificity of the analytical column of the automatic amino acid analyzer permits the routine analysis of taurine in preparations.

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The Study of Stability of Oral Pharmaceutical Liquid Preparation II

  • Kang, Min-Kyung;Park, So-Min;Choi, So-Young;Kim, Kil-Soo
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.226.1-226.1
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    • 2003
  • The available period of oral pharmaceutical liquid preparations was decided according to the study of the stability of unopened preparations. But if one reuses the drug after opening the sealed cap, the major components of the drug could change in quality. In addition, there isn`t any accurate information about the available period of opened oral pharmaceutical liquid preparations. In this study, a long term test, an accelerated test and a microbial limit test are run with C (pseudoephedrine and triprolidine), D (ibuprofen) that are marketed and used frequently. (omitted)

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Herbal topical anesthetics in dentistry: an exploratory review

  • Sunnypriyatham, Tirupathi;Dharmarajan, Gopalakrishnan;Sanjeevani, Deshkar
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.22 no.6
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    • pp.419-426
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    • 2022
  • Topical anesthetics are routinely used in dental practice for various purposes. They are usually available at higher dosages and have serious potential adverse reactions, such as seizures, anaphylaxis, and acquired methemoglobinemia. To date, the scope of application of herbal plants and their extracts, which have medicinal properties, has been elaborated in the field of dentistry. The growing interest in herbal medication can be attributed to the increased safety profile of herbal agents, in contrast to synthetic preparations that have a higher risk of systemic complications. Herbal preparations can induce topical anesthesia with minimal side effects. Recently, many studies have reported the use of topical herbal preparations. The current review aimed to evaluate data from various articles comparing the capacity of herbal topical anesthetic formulations and conventional synthetic anesthetics in reducing pain perception when used as local anesthesia before dental procedures.

Spectrofluorimetric determination of Trimethoprim in pharmaceutical preparations

  • Amneen Mohammed Alsayegh;Abbas N. Alshirifi
    • Analytical Science and Technology
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    • v.36 no.5
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    • pp.250-257
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    • 2023
  • The development of a spectrofluorimetric method for the determination of trimethoprim according to the reaction between O-phthalaldehyde (OPA) in highly alkaline media, and 2-mercaptoethanol (2ME) and this reaction gives fluorescent product measured at (458) nm when excited at (342) nm. The optimization of the analytical parameters that influence intensity was investigated. The intensity of fluorescence of the formed product was linearly related to the concentration of trimethoprim in the (100-1200) ng mL-1 range. The limit of detection and limit of quantification were estimated to be (22.54) ng mL-1 and (75.15) ng mL-1 respectively. The utility of the proposed methods was successfully verified by analysis of trimethoprim in pure and real pharmaceutical preparations with high accuracy, the recovery percentages Re%, were found to be (100.5) % and (99.76) % for pure drug and pharmaceutical preparations respectively.

Determinants of Pastors' Economic Preparations for Old Age (목회자의 경제적 노후 준비 결정요인)

  • Song, Chang-Kook
    • Korean Journal of Social Welfare
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    • v.61 no.3
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    • pp.29-54
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    • 2009
  • This study is intended to figure out determinants affecting the economic preparations for old age of pastors from major four protestant associations having a church ministerial pension system: the General Assembly of Presbyterian Church in Korea (GAPCK), the Presbyterian Church of Korea (PCK), the Presbyterian Church in the Republic of Korea (PROK), and the Korean Methodist Church (KMC). Thereby, it conducted a survey to 452 pastors from the four religious associations in Korea. The followings sum up the results of this research. First, it was shown that the conventional idea that there is no need for pastors to prepare for their old age or their preparations for old age imply disbelief had been diminished. Second, there were few pastors who had made economic preparations for their old age privately. Third, associations adopting a compulsory church ministerial pension system were PCK, PROK, and KMC indicating a high occupation of more than 75% whereas GAPCK with an optional system showed a very low percentage of 11.5%. Fourth, with regard to the national pension system, the associations except for PROK (61.8%) had more non-enrolled pastors (53.3%), and they responded economic difficulty as the biggest reason for the unenrollment. Fourth, determinants affecting their economic preparations for old age were academic career, total income, church independency, church reserving, and national pension enrollment. Fifth, among the pastors from the four associations, the ones of PROK prepared for their old age best in consideration of GAPCK. According to the results of this paper, the most critical determinant affecting pastors' economic preparations for old age was total income. Pastors with higher income can make church ministerial pension, national pension, and private preparations while the ones with lower income cannot afford for public as well as private preparations; that is, there exists a polarization phenomenon in pastors' economic preparations for old age. Therefore, it is necessary to make devices to narrow the income gap between pastors in religious associations. Second, even in the associations having a compulsory church ministerial pension system, many pastors were not insured, so it is needed to reform or improve the pension system. Third, it is also required to better the national pension system and change the recognition on it.

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Drugs Most Frequently Used in OPD of Yeungnam University Hospital: March to August, 1985 (영남대학교 의과대학 부속병원 외래환자에 대한 약물처방 동향의 분석)

  • Lee, Kwang-Youn;Kim, Won-Joon;Kim, Sung-Hoon
    • Journal of Yeungnam Medical Science
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    • v.2 no.1
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    • pp.95-102
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    • 1985
  • This report offers descriptive data about the drugs utilized in out patient department (OPD) of Yeungnam University Hospital (YUH) in the period of march to august in 1985. The data in this report were produced by the computerized totalization of the number of mentions of individual drugs included in the prescriptions. The 100 drug entries that were most frequently recorded are listed in rank order. The listing is arbiturarily restricted to the drugs that were prescribed as single preparations, the drugs of basis of compound preparations and the drugs of adjuvent or corrective of compound preparations that have significant therapeutic effects either by generic names. And in addition, the listing also involves the compound preparations used in relatively large frequency, and the individual components of which have the unique pharmacological actions each other by proprietary names. And all routes of administrations were allowed. The 10 drugs most frequently named are diazepam, aluminum compounds, acetaminophen, isoniazid, metoclopramide, $polaramine^{(R)}$, carboxymethylcystem, ephedrine, codeine and caroverine in order. The 521,855 drug mentions listed as above are described by the chief therapeutic usage that each is intended to apply generally. The drugs which account the largest proportion of total mentions were those acting on the central nervous system (20.57%), including tranquilhzers and sedative hypnotics (11.71%), analgesic antipyretics (5.55%), antidepressants (2.15%) etc. Gastrointestinal drugs and smooth muscle preparations (18.64%) included antacids and anti-ulcer drugs (9.24%), antiemetics (3.57%), spasmolytics (3.14%) and others. Respiratory drugs (16.11%) included expectorants and cough preparations (10.99%) and bronchodilators (5.12%). Chemotherapeutic agents (15.12%) included the antiTbc drugs (7.09%) most frequently, and the penicillins (3.33%) accounted the largest proportion among the antibiotics. Cardiovascular drugs (5.64%) included cardiac drugs and coronary vasodilator (4.12%) and antihypertensives and vasodilators (1.06%). And anti-inflammatory drugs (4.33%), vitamins of single preparations (3.76%), hormones and their antagonists (3.29%), common cold preparations (3.12%), diuretics (2.81%), drugs supporting liver function (2.02%), drugs affecting autonomic nervous system(1.89%) including anti-glaucomas, atropine and cerebral vasodilators, antihistamine drugs (1.02%) and disinfectants (0.74%) were following in order. The data in this report were compared to those reported by H. Koch, et al. in United States (US), 1981 as "Drugs Most Frequently Used in Office Practice:National Ambulatory Medical Case Survey, 1981." Cardiovascular drugs prescribed in YUH were much less in proportion than in US (10.56%), but gastrointestinal drugs accounted the larger proportion than in US (3.72%). Expectorants and cough preparations in YUH also accounted the larger proportion than in US (2.74%). In conclusion, in the period of march to august, 1985, OPD of YUH prescribed the CNS drugs including diazepam most frequently, and gastrointestinal, repiratory and chemotherapeutic drugs in next orders. It is supposed that the eating habits of Koreans and a unique atmospheric condition in Taegu as a basin were some important factors that affected the proportions of drugs acting on gastrointestinal and respiratory tracts.

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Biphasic Mechanical Responses of Rat Thoracic Aorta to Irradiation with $250{\sim}500\;nm$ Light (돼지 관상동맥 및 흰쥐 흉부대동맥에서 자외선 및 가시광선 조사시 파장에 따른 기계적 반응과 Cyclic GMP의 농도변화)

  • Kook, Hyun
    • The Korean Journal of Pharmacology
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    • v.31 no.3
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    • pp.285-290
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    • 1995
  • This study was undertaken to define the varying responses of vascular smooth muscle to different wavelengths of ultraviolet radiation and to relate them to the changes in cyclic GMP contents. The ring preparations of rat thoracic aorta with intact or removed endothelium were irradiated with the ultraviolet or visible light (UVR) of wavelengths in step of 10 nm between 250 and 500 nm from xenon lamp of a spectrofluorometer, and the changes in vascular tension were recorded. For cyclic GMP assay, the preparations, pretreated with phenylephrine as in the tension experinents, were frozen after irradiation and homogenated in trichloroacetic acid. The supernatant was extracted with ether and the cyclic GMP contents were measured with radioimmunoassay. In the endothelium-intact preparations, biphasic responses, vasoconstriction (UVR-contraction) followed by vasodilatation (UVR-dilatation), were observed. The maximal UVR-contraction was observed at 320 nm, while the maximal vasodilatation was elicited at 420 nm. In the endothelium-removed rings, however, only vasodilatation was observed, with the maximal vasodilatation taking place at 370 nm. The cyclic GMP contents were not affected by the Irradiation with 320 nm for 30 sec or 1 min in the endothelium-intact preparations, while it was significantly increased by 380 and 420 nm. In the endothelium-removed preparations, UVR of 370 nm markedly increased the cyclic GMP contents. The present study indicates that the increase in cyclic GMP is closely related to vasodilatation induced by UVR of 420 nm in the endothelium-intact or 370 nm in the denuded preparations, whereas it is not involved in the vasoconstriction induced by UVR of 320 nm in the intact rings, and the mechanism leading to UVR-contraction remains to be clarified. These observations suggest that nitric oxide-cyclic GMP system is closely related to the UVR-dilatation in rat aortic preparation, while it is not involved in the UVR contraction.

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Increase of Growth on Cool Season Turfgrass by Foliar Application of Preparations of Turfgrass Fertilizer during Fall Season (잔디 비료 제형의 엽면 살포가 가을철 한지형 잔디의 생장 증대)

  • Koo, Jun Hwak;Heo, Hyug Jae;Kim, Yang Sun;Yun, Jeong Ho;Chang, Seog Won;Lee, Seong Jun;Chang, Taehyun
    • Weed & Turfgrass Science
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    • v.3 no.1
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    • pp.41-49
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    • 2014
  • Four preparations of liquid turfgrass fertilizers were tested cool season turfgrasses during fall season. The preparations of PS-A, PS-B, PH-C and PH-D for commercial products were contained with essential nutrient elements, seaweed extract, amino acids, and humus substance. Growth and quality of creeping bentgrass (Agrostis palustris Huds cv. Penn-A1) and Kentucky bluegrass (Poa pratensis L.) mixture (Midnight 33%, Moonlight 33%, Prosperity 33%) were evaluated by normalized difference vegetation index (NDVI), root length and fresh weight, shoot density, turf color, and chlorophyll content. Three foliar sprays of 4 preparations with an interval of 7 days were made in the fall of 2013 in the sod production field at Hapchun, Korea. No significant difference among 3 preparations was found in NDVI of creeping bentgrass. However, PS-A was significantly increased NDVI of Kentucky bluegrass. Two to three applications of PS-A significantly increased chlorophyll content and turf color. Three foliar sprays of PS-A and PS-B were significantly increased the shoot density of Kentucky bluegrass on 20 days after final application. These results may indicate that the use of some preparation is beneficial in producing higher quality turfgrass sod with better color and chlorophyll content during fall season.

Influence of the Elderly Feeling of Self-Efficacy on Preparation after Retirement -Focused on the Mediating Effect of Social Capital- (노인의 자기 효능감이 노후준비에 미치는 영향 -사회적 자본의 매개 효과를 중심으로-)

  • Shin, Kun-Young;Ko, Jea-Ug
    • The Journal of the Korea Contents Association
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    • v.17 no.9
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    • pp.255-267
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    • 2017
  • The purpose of this research is to secure the foundational data for analyzing the mediating role of social capital from the influences of the feeling of self-efficacy of the elderly on the preparations for the old age. The subjects of this study were 518 questionnaires collected from March 20 to April 1, 2016 for the elderly over 60 years old who were living in S city. Regarding the data, the SPSS 20.0 and the AMOS 20.0 were used. And, the results of this research were the following: First, if we take a look at the influences of the feeling of self-efficacy on social capital, the feeling of self-efficacy has the positive influences. And, second, the influences of the feeling of self-efficacy on the preparations for the old age, also, are positive. Third, the influences of the social capital on the preparations for the old age, too, are positive. As such, we can find out that both the direct and indirect effects were shown. Lastly, we can find out that the feeling of self-efficacy has the partial mediating effects on the social capital and the preparations for the old age. Consequently, although the feeling of self-efficacy is insufficient with regard to the economic preparations, we can positively find out that it was able to effectively derive the satisfaction in life by utilizing the social capital. In preparation for the super-aged society, the improvements and the expansions of the social programs and the services resulting from them are needed through the establishment of a foundation regarding the life-periodical, social participation, the establishment of a socially-shared system that can be continued, and the policy of strengthening the social capital.

Determination of Ephedrine Hydrochloride and its Analogs by GC-FPD (GC-FPD를 이용한 염산에페드린 및 그 관련물질의 정량)

  • 박만기;조영현;이용문;노일협
    • YAKHAK HOEJI
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    • v.30 no.5
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    • pp.214-219
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    • 1986
  • A gas chromatographic procedure is described for the quantitative analysis of ephedrine hydrochloride, pseudoephediiiie hydrochloride and norephedrine hydrochloride in pharmaceutical preparations. The procedure was based upon the determination of thioureas formed from amines and phenylisothiocyanate. The recoveries of ephedrine, pseudoephedrine and norephedrine from pharmaceutical preparations were 100.7(S.E. 0.9), 99.5(0.8), 99.1(0.8) and 99.1%(O.9), respectively. The high accuracy and precision of this assay were inherent in the flame photometric detectors normally used in gas chromatography.

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