• The Journal of Korean Physical Therapy
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• 제22권4호
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• pp.1-6
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• 2010

Purpose: This study was designed to evaluate the clinical utility of the Four square step test (FSST) for predicting falls in stroke patients, to compare the ability of the FSST test to discriminate between subgroups of fallers, and to determine if the test has any predictive value in identifying stroke patients who will fall. Methods: Stroke patients (N=37) who could walk at least 50 m with minimal assistance were recruited consecutively when attending a physical therapy session during their rehabilitation. Dynamic standing balance was measured using the FSST. The main outcome measures were FSST time and fall number. Numbers of falls were compared with FSST scores. Differences between the groups in FSST scores were examined using a t-test and 1-way analysis of variance. Post hoc analysis using the Tukey B procedure was used to identify specific group differences. Alpha was set at 0.05. Results: A total of 15 participants (40.5%) reported falls 6 had recurrent falls (2 falls) and 9 fell once. The mean FSST time differed significantly between groups with zero and multiple falls. A cutoff score of greater than 17 seconds on the FSST was associated with a sensitivity of 83% and a specificity of 84% for the identification of subjects with multiple risk factors for falls. Conclusion: The FSST is a feasible and valid clinical test of dynamic standing balance and can predict falls in post-stroke patients.

• Computers and Concrete
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• 제19권5호
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• pp.467-475
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• 2017

The purpose of this study is to establish a prediction model for the electrical resistivity ($E_r$) of self-consolidating concrete by using waste LCD (liquid crystal display) glass as part of the fine aggregate and then, to analyze the results obtained from a series of laboratory tests. A hyperbolic function is used to perform nonlinear multivariate regression analysis of the electrical resistivity prediction model, with parameters such as water-binder ratio (w/b), curing age (t) and waste glass content (G). Furthermore, the relationship of compressive strength and electrical resistivity of waste LCD glass concrete is also found by a logarithm function, while compressive strength is evaluated by the electrical resistivity of non-destructive testing (NDT). According to relative regression analysis, the electrical resistivity and compressive strength prediction models are developed, and the results show that a good agreement is obtained using the proposed prediction models. From the comparison between the predicted analysis values and test results, the MAPE value of electrical resistivity is 17.0-18.2% and less than 20%, the MAPE value of compressive strength evaluated by $E_r$ is 5.9-10.6% and nearly less than 10%. Therefore, the prediction models established in this study have good predictive ability for electrical resistivity and compressive strength of waste LCD glass concrete. However, further study is needed in regard to applying the proposed prediction models to other ranges of mixture parameters.

• 통합자연과학논문집
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• 제8권2호
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• pp.89-98
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• 2015

Chemoattractant receptor homologous molecule expressed on Th2 cells (CRTh2) is a G-protein coupled receptor targeted for inflammatory diseases such as asthma, allergic rhinitis and atopic dermatitis. In this study, pharmacophore modeling and comparative molecular field analysis (CoMFA) were performed on the series of 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl) acetic acids derivatives. Five highly active compounds were used for generation of pharmacophore models using GASP module. The best pharmacophore model was selected and used as template for the alignment of compounds which was used for CoMFA analysis. The best predictions obtained for CoMFA was $q^2=0.545$, $r^2=0.756$. The predictive ability of the model was investigated using 15 test set compounds. Contour maps suggested that presence of bulky substituents at $5^{th}$ position of benzene ring connected to suphur atoms attached to imidazol ring will increase the activity of the compounds. The results obtained from this study will be useful to design more potent CRTh2 antagonists.

• 통합자연과학논문집
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• 제11권2호
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• pp.107-112
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• 2018

p38 MAP kinase belongs to the Mitogen-activated protein (MAP) kinase family; a serine/threonine kinase. It plays an important role in intracellular signal transduction pathways. It is associated with the development and progression of various cancer types making it a crucial drug target. Present study involves the HQSAR analysis of recently reported imidazo[1,2-b]pyridazine derivatives as p38 MAP kinase antagonists. The model was generated with Atom (A), bond (B), chirality (Ch), and hydrogen (H) parameters and with different set of atom counts to improve the model. An acceptable HQSAR model ($q^2=0.522$, SDEP=0.479, NOC=5, $r^2=0.703$, SEE=0.378, BHL=97) was developed which exhibits good predictive ability. A contribution map for the most active compound (compound 17) illustrated that hydrogen and nitrogen atoms in the ring A and ring B, as well as nitrogen atom in ring C and the hydrogen atom in the ring D provided positive activity in inhibitory effect while, the least active compound (compound 05) possessed negative contribution to inhibitory effect. Hence, analysis of produced HQSAR model can provide insights in the designing potent and selective p38 MAP kinase antagonists.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2008년도 International Symposium on Remote Sensing
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• pp.151-154
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• 2008

Information on the area and spatial distribution of crop fields is needed for biomass production, arrangement of water resources, trace gas emission estimates, and food security. The present study aims to monitor crops status during the growing season by estimating its aboveground biomass and leaf area index (LAI) from field reflectance taken with a hand-held radiometer. Field reflectance values were collected over specific spectral bandwidths using a handheld radiometer(LI-1800). A methodology is described to use spectral reflectance as indicators of the vegetative status in crop cultures. Two vegetation indices were derived from these spectral measurements. In this paper, first we analyze each spectral reflectance characteristics of vegetation in the order of growth stage. Vegetation indices (NDVI, GNDVI) were calculated from crop reflectance. And assess the nature of relationships between LAI and VI, as measured by the in situ NDVI and GNDVI. Among the two VI, NDVI showed predictive ability across a wider range of LAI than did GNDVI. Specific objectives were to determine the relative accuracy of these two vegetation indices for predicting LAI. The results of this study indicated that the NDVI and GNDVI could potentially be applied to monitor crop agriculture on a timely and frequent basis.

• 자원ㆍ환경경제연구
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• 제14권1호
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• pp.201-220
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• 2005

최근 들어, 우리는 유례 없는 국제 유가의 급등현상을 목격하고 있다. 이러한 시점에서, 의문점은 유가에 대한 예측 가능성과 이의 정확도에 관한 것이다. 본 연구에서는 전문가 예측시스템과 비교하여 선물가격의 상대적인 예측력에 관하여 통계적으로 분석하고자 한다. 이를 위해, 미국 텍사스 중질유(WTI)의 현물가격과 선물가격을 활용하여, 예측 정확도에 관한 단순한 형태의 통계적 분석과 함께 분석수단별 예측오차 차이의 유의성에 관한 체계적 분석을 시도하였다. 통계적 검정결과에 따르면, WTI 선물시장을 활용한 예측은 미국 에너지정보기구(EIA)의 예측과 비교하여 뒤지지 않는 것으로 판명되었다. 결과적으로, 석유 생산자와 소비자 모두가 WTI 선물시장을 유가 예측의 유용한 수단으로 활용할 수 있고, 이로써 효율적인 자원배분 측면에서도 유익할 것으로 판단된다.

• 한국치위생학회지
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• 제9권3호
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• pp.536-544
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• 2009

Purpose : This study aimed to examine the relationship between intragroup peer evaluation and self-directed learning readiness(SDLR) in an Introduction to Education class that used a team based learning(TBL). Moreover, it identified the specific components of the SDLR that predicted the peer evaluation results. Method : The research subject pool comprised of 87 $1^{st}$ students in D Health College. Each team was composed of 6~8 members, each of whom evaluated all other members on his or her team SDLR was measured by using SDLR-K-96. Results : SDLR and peer assessment scores had a positive relationship, confirming that SDLR was an important variable that could predict the peer evaluation scores. Among the SDLR factors, 'openness to challenge' and 'self-confidence as a learner' was shown to have the predictive power for the peer assessment. Conclusion : The colleges should provide dental hygiene students with learning opportunities on ability to do self-directed learning through diverse learning methods such as team based learning.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.372-372
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• 2000

In this paper, we propose Neuro Fuzzy Polynomial Networks(NFPN) based on Polynomial Neural Network(PNN) and Neuro-Fuzzy(NF) for model identification of complex and nonlinear systems. The proposed NFPN is generated from the mutually combined structure of both NF and PNN. The one and the other are considered as the premise part and consequence part of NFPN structure respectively. As the premise part of NFPN, NF uses both the simplified fuzzy inference as fuzzy inference method and error back-propagation algorithm as learning rule. The parameters such as parameters of membership functions, learning rates and momentum coefficients are adjusted using genetic algorithms. As the consequence part of NFPN, PNN is based on Group Method of Data Handling(GMDH) method and its structure is similar to Neural Networks. But the structure of PNN is not fixed like in conventional Neural Networks and self-organizing networks that can be generated. NFPN is available effectively for multi-input variables and high-order polynomial according to the combination of NF with PNN. Accordingly it is possible to consider the nonlinearity characteristics of process and to get better output performance with superb predictive ability. In order to evaluate the performance of proposed models, we use the nonlinear function. The results show that the proposed FPNN can produce the model with higher accuracy and more robustness than any other method presented previously.

• Toxicological Research
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• 제22권4호
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• pp.423-429
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• 2006

Recent reports on the photocarcinogenicity and photogerotoxicity of many compounds led to an increasing awareness for the need of a standard approach to test for photogenotoxicity. The comet assay has been recently validated as a sensitive and specific test system for the quantification of DNA damage. Thus, the objectives of this study are to investigate the utility of photo-comet assay for detecting photo-mutagens, and to evaluate its ability to predict rodent photo-carcinogenicity. Photo-comet assays were performed using L5178Y $Tk^{+/-}$ mouse lymphoma cells on five test substances (8-methoxypsoralen, chlorpromazine, lomefloxacin, anthracene and retinoic acid) that demonstrated positive results in photocarcinogenicity tests. For the best discrimination between the test substance-mediated DNA damage and the undesirable DNA damage caused by direct UV absorption, a UV dose-response of the cells in the absence of the test substances was firstly fnalized. Out of 5 test substances, positive comet results were obtained for chlorpromazine, lomefloxacin, anthracene and retinoic acid while 8-methoxypsoralen found negative. An investigation into the predictive value of this photo-comet assay for determining the photocarcinogenicity showed that photo-comet assay has relatively high sensitivity. Therefore, the photo-comet assay with mammalian cells seems to be a good and sensitive predictor of the photocarcinogenic potential of new substances.

• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2006년도 PAN PACIFIC CONFERENCE vol.2
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• pp.365-372
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• 2006

In this paper, the possibility of statistical modeling from the pulp and peroxide bleaching condition variables to predict optical properties of a bleached chemimechanical pulp used in a newsprint paper machine at Mazandaran Wood and Paper Industries Company (MWPI) was studied. Due to the variations in the opacity and the brightness of the bleached pulp at MWPI and to tackle this problem, it was decided to study the possibility of modeling the bleaching process. To achieve this purpose, Multi-variate Regression Analysis was used for model building and it was found that there is a relationship between independent variables and pulp brightness as well as pulp opacity, consequently, two models were constructed. Then, model validation was carried out using new data set in the bleaching plant at MWPI to test model predictive ability and its performance.