• Archives of Plastic Surgery
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• v.42 no.2
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• pp.150-158
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• 2015

Background Fat is widely used in soft tissue augmentation. Nevertheless, it has an unpredictably high resorption rate. Clinically, external expansion with negative pressure is used to increase fat graft survival. In this study, fat graft recipient sites were preconditioned by external application of negative pressure in order to test for improvements in vascularity and fat graft survival. Methods Negative pressure was applied randomly to either the left or right dorsal ear of 20 New Zealand male white rabbits at a pressure of -125 mm Hg. The negative pressure was removed one week after the skin perfusion was measured. The skin flap at each ear was elevated, and 1 g of fat was grafted above the dorsal perichondrium. After one week, the fat weight, microvessel density, mature vessel density of the skin and fat, and amount of glycerol released were measured. Three months after the grafting, the same measurements were performed, with the exception of glycerol release. Results The fat survival rate of the experimental group ($75.4%{\pm}3.9%$) was higher than that of the control group ($53.1%{\pm}4.3%$) (P<0.001). Skin perfusion was higher in the experimental group. The glycerol release in the experimental group was significantly higher than in the control. The microvessel density of the skin and fat was significantly higher in the experimental group. Three months after the grafting, the skin and fat mature vessel density was significantly higher in the experimental groups. Conclusions Negative pressure prior to fat grafting increased the vascularity of the recipient site, and, accordingly, enhanced fat graft survival.

• Journal of Pharmaceutical Investigation
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• v.22 no.3
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• pp.35-47
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• 1992

Hydrogel coated ring shaped ocular inserts (containing the antibiotic, tylosin tartrate) were used in an evaluation of the effectiveness of polymeric ocular drug release devices for treating infectious bovine keratoconjunctivitis. The in vivo experiments represent the first experiments using hydrogel ocular inserts containing an antibiotic for treating infectious bovine keratoconjunctivitis. In the infection tests, ten calves. were challenged with $2.4{\times}10^8{\sim}1.6{\times}10^9$ Moraxella bovis (a bacterium) colonies per eye following two ten minute ultraviolet radiation eye preconditioning exposures. Ninety five percent of the eyes (19 of 20 eyes) were successfully infected by this method. All infected eyes were monitored for the presence of the bacteria quantitiatively, and clinical observations were made for 14 days. The test was performed by three consecutive steps: 1) inoculation with 2 ultraviolet (UV) radiations, 2) growth of bacterial colonies and 3) treatment with medicated ring-shaped devices. The first. bacteriological measurements after 2 UV exposures were performed at day 3 of the tests. At day 7 after inoculation of both eyes of a calf with M. bovis, a medicated or a non-medicated ring-shaped device was inserted into each eye of a calf. The eye receiving the non-medicated ring was taken as a control for comparison with the eye that received a medicated ring. During the next 7 day period following a medicated ring insertion, the number of bacteria in the treated eyes dropped dramatically to negligible levels (0 to 30 colony forming units/swab), while the control eyes which received a non-medicated ring still exhibited a relatively high number of bacteria ($10^3\;to\;10^6$ colony forming units/swab). The number of bacteria was significantly reduced by the antibiotic released from the medicated ocular insert.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.20 no.2
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• pp.79-91
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• 2017

This study was conducted to find out the physical properties and soil shearing strength reinforcement effect of herbaceous plants for the slope revegetation works. Two native plants(Pennisetum alopecuroides and Miscanthus sinensis) were used for this experiment, because they have excellent seed germination rates without preconditioning, and grow naturally around rivers. To identify the physical properties, the partial dry weight of plants were investigated. To identify the soil shearing strength reinforcement effect, the respective soil shearing strengths of the control soils, Pennisetum alopecuroides, Miscanthus sinensis samples were measured. Also, we did a correlation analysis to examine the relation of shearing strength to plant features. The results are summarized as follows: 1. The average dry weight of Pennisetum alopecuroides samples consists of 52.36% above ground and 47.64% at root. And in dry weight, 78.24% of it's root distributes within 10 cm in soil depth. Meanwhile the average dry weight of Miscanthus sinensis samples consists of 52.91% above ground and 47.09% at root. And in dry weight, 82.95% of it's root distributes within 10 cm in soil depth. 2. The results of correlation analysis showed that for both Pennisetum alopecuroides and Miscanthus sinensis, it could not be said that there was any correlation between shearing strength and plant characteristics, and statistically they were not meaningful. 3. In the shearing strength test with control soils, Pennisetum alopecuroides, Miscanthus sinensis as subjects, the differences in shearing strength measurement results were modest, and the order was shown as control soils < Pennisetum alopecuroides < Miscanthus sinensis, so the soil shearing strength reinforcement effect by the Pennisetum alopecuroides and the Miscanthus sinensis on loamy sand at river banks surface was confirmed.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.37 no.1
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• pp.17-27
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• 2009

Two-phase RoeM and AUSMPW+ schemes are preconditioned for the simulation of all Mach number flows, which are generally of interest for many gas-liquid two-phase application problems, because of large speed of sound in liquid region and low speed of sound in mixture or gas region. Conventional characteristic based schemes lose their accuracy or robustness in low Mach number flows, because their numerical dissipation terms are scaled by speed of sound, which is too large compared with local velocity magnitude in a low Mach region. All speed versions of RoeM and AUSMPW+ reflect the eigenvalues of the preconditioned governing system, which have the same order of magnitude even in low Mach number region. From the asymptotic analysis, it is observed that the discretized system by the developed schemes is consistent with the continuum system in the incompressible limit. The numerical results show the accurate and robust behavior of the proposed shcemes for all speed two-phase flows.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.12
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• pp.974-981
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• 2017

Globally, owing to the rapid expansion of radio stations overseas, the frequency coordination system is managed as a preconditioning system. As a result, it is predicted that many types of radio stations will be established for domestic purposes, such as 5G, low-power IoT devices with long distance, based on licenses and non-license in the future. Many problems such as unnecessary launching of radio resources and spectrum-sharing technology exist, and it is necessary to consider the introduction of the abovementioned system and other plan system. In this paper, we explore the outline of radio station licensing and introduce the contents of the survey on another industry licensing. The plans were studied by discussing problems that may occur in future, through comparative analysis of radio stations and other industry licensing. Moreover, the differences were compared and analyzed using graphs. Finally, we discussed the problems convergence products such as drone may offer in the future.

• Journal of the korean academy of Pediatric Dentistry
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• v.25 no.4
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• pp.761-771
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• 1998

In this study, attempt has been made to evaluate the effect of $CO_2$ laser irradiation on enamel surface structure and the bond strength of sealant material. Conventional acid etching was used as a control technic for comparison. The results obtained from this experiment were as follows; 1. The highest mean shear bond strength value was observed in samples of Group I (acid-etching) with the statistical significance(p<.05) between all the other groups. 2. The shear bond strength in Group IV was the lowest among laser etching groups. but there were no significant difference between them(p>.05). 3. Scanning electron microscopic observation showed that the rough and irregular surface was created by $CO_2$ laser treatment with the formation of numerous pores, micro-cracks, and small bubble-like inclusion. Increasing the energy density induced localized surface melt with a thin smooth glaze-like appearance. 4. In acid-etched control specimen cohesive failure predominated, whereas adhesive failure was the main mode in laser-treated group. Based upon the above-mentioned results, it can be assumed that the $CO_2$ laser is not an adequate substitute for the acid-etch technique in enamel preconditioning. More studies are required to explore the effective condition of laser irradiation which could attain the better bond strength of restorative materials.

• The Journal of Information Systems
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• v.26 no.4
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• pp.1-15
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• 2017

Purpose Through the provision of real time performance information about who is contributing and who is not in Electronic Brainstorming, prior studies evidenced a significant performance gain. However, it has been observed that the quantity-based performance feedback alone does not have enough restrictiveness to guide the performance behavior throughout the idea generation session. We included the notion of goal setting into the process performance feedback mechanism in an effort to regulate performance behavior and to better understand why individuals in Electronic Brainstorming are not obtaining enough stimulation benefits in the group interaction process. Design/methodology/approach We had developed real-time visual process performance feedback and modified to include goal setting. This mechanism visually displays individuals' performances two-dimensionally (quality for each idea vertically and quantity of ideas horizontally along with their goals). As individuals' contributions accumulate, the mechanism reveals performance histories by connecting the sequence of ideas in a time-series format, telling stories of individuals' performances. Then, we compared the performance outcome from this study with the outcomes from two prior studies (i.e., Jung et al., 2010 and Jung, 2014). Findings The results showed that the inclusion of goal setting into the process performance feedback solved the issue in the previous study. That was the lower than expected magnitude of performance enhancement of process performance feedback when compared to that of quantity-based feedback. It appears that goals as a motivational technique provide standards for systematic self-evaluation, serving as a cue to regulate performance behavior by strengthening the linkage between effort and performance. Thus, goals seem to set up a self-fulfilling prophecy, preconditioning better performance. However, the outcome still showed that its performance magnitude is unsatisfactory because the outcome of this study turned out to be close to the outcome of just quantity-based performance feedback in Jung et al.'s (2010) study.

• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.868-869
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• 2005

• Archives of Plastic Surgery
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• v.44 no.5
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• pp.384-389
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• 2017

Background The aim of this study was to investigate the effects of remote ischemic conditioning on ischemia-reperfusion injury in rat muscle flaps histopathologically and biochemically. Methods Thirty albino rats were divided into 5 groups. No procedure was performed in the rats in group 1, and only blood samples were taken. A gracilis muscle flap was elevated in all the other groups. Microclamps were applied to the vascular pedicle for 4 hours in order to achieve tissue ischemia. In group 2, no additional procedure was performed. In groups 3, 4, and 5, the right hind limb was used and 3 cycles of ischemia-reperfusion for 5 minutes each (total, 30 minutes) was applied with a latex tourniquet (remote ischemic conditioning). In group 3, this procedure was performed before flap elevation (remote ischemic preconditoning). In group 4, the procedure was performed 4 hours after flap ischemia (remote ischemic postconditioning). In group 5, the procedure was performed after the flap was elevated, during the muscle flap ischemia episode (remote ischemic perconditioning). Results The histopathological damage score in all remote conditioning ischemia groups was lower than in the ischemic-reperfusion group. The lowest histopathological damage score was observed in group 5 (remote ischemic perconditioning). Conclusions The nitric oxide levels were higher in the blood samples obtained from the remote ischemic perconditioning group. This study showed the effectiveness of remote ischemic conditioning procedures and compared their usefulness for preventing ischemiareperfusion injury in muscle flaps.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.10
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• pp.4329-4333
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• 2015

Background: To investigate the change of frequency and immuno-inhibitory function of myeloid-derived suppressor cells (MDSCs) after treatment of cisplatin (DDP) in A375 human melanoma model. Materials and Methods: BALB/c nude mice were inoculated with A375 cells to establish the human melanoma model and randomly divided into control group given normal saline (NS) and experimental group treated with DDP (5 mg/kg). The percentages of MDSCs in the tumor tissue and peripheral blood after DDP treatment were detected by flow cytometry. The proliferation and interferon-${\gamma}$ (IFN-${\gamma}$) secretion of T cells co-cultured with MDSCs were analyzed through carboxyfluorescein succinimidyl ester (CFSE) labeling assay and enzyme-linked immunospot (ELISPOT) assay, respectively. Results: In A375 human melanoma model, DDP treatment could significantly decrease the percentage of MDSCs in the tumor tissue, but exerted no effect on the level of MDSCs in peripheral blood. Moreover, DDP treatment could attenuate the immuno-inhibitory function of MDSCs. T cells co-cultured with DDP-treated MDSCs could dramatically elevate the proliferation and production of INF-${\gamma}$. Conclusions: DDP can decrease the frequency and attenuate immuno-inhibitory function of MDSCs in A375 melanoma model, suggesting a potential strategy to augment the efficacy of combined immunotherapy.