• Title/Summary/Keyword: precise stage

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Early-stage Diagnosis of Bladder Carcinoma by a Clinical Pharmacist's Effective Anti-coagulation Service in a Patient with Anticoagulation Therapy: a Clinical Case Report (항응고제 투여 환자에서 약사의 효과적인 ACS를 통한 방광암 조기발견 사례)

  • An, Sung-Shim;Bang, Joon-Seok;La, Hyen-Oh
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.1
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    • pp.85-87
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    • 2010
  • Recently, the prevalence of bladder cancer is increasing in the Korean society. As the risk factors of bladder carcinoma are variable, the early-stage diagnosis is regarded the best preventive practice. Hematuria is a specific sign of the malignancy as well as a kind of various medication-related adverse reactions. Some anti-coagulation therapy can cause bleedings including hematuria to the patients with cardiovascular diseases such as paroxysmal atrial fibrillation (PAF). Therefore, to the clinical pharmacists working in the anti-coagulation services (ACS), a closer monitoring of patients can give an opportunity to find certain ailments unexpectedly. In this case, a patient with PAF had episodes of sporadic hematuria in the course of warfarin therapy even though with its low levels of INR. An ACS pharmacist found a discrepancy between the bleeding symptoms and INR values, and recommended properly the patient to refer urologist. Fortunately, an early-stage of bladder carcinoma was found then followed by an excision performed to the lesion. Therefore, alert-minded and precise monitoring done by ACS pharmacist could optimize the therapeutic outcomes as well as increase the quality of life of the patient.

Implementation of Deep Learning-based Label Inspection System Applicable to Edge Computing Environments (엣지 컴퓨팅 환경에서 적용 가능한 딥러닝 기반 라벨 검사 시스템 구현)

  • Bae, Ju-Won;Han, Byung-Gil
    • IEMEK Journal of Embedded Systems and Applications
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    • v.17 no.2
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    • pp.77-83
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    • 2022
  • In this paper, the two-stage object detection approach is proposed to implement a deep learning-based label inspection system on edge computing environments. Since the label printed on the products during the production process contains important information related to the product, it is significantly to check the label information is correct. The proposed system uses the lightweight deep learning model that able to employ in the low-performance edge computing devices, and the two-stage object detection approach is applied to compensate for the low accuracy relatively. The proposed Two-Stage object detection approach consists of two object detection networks, Label Area Detection Network and Character Detection Network. Label Area Detection Network finds the label area in the product image, and Character Detection Network detects the words in the label area. Using this approach, we can detect characters precise even with a lightweight deep learning models. The SF-YOLO model applied in the proposed system is the YOLO-based lightweight object detection network designed for edge computing devices. This model showed up to 2 times faster processing time and a considerable improvement in accuracy, compared to other YOLO-based lightweight models such as YOLOv3-tiny and YOLOv4-tiny. Also since the amount of computation is low, it can be easily applied in edge computing environments.

MOVEMENT CONTROL OF HIGH-RISE BUILDINGS DURING CONSTRUCTION

  • Taehun Ha;Sungho Lee;Bohwan Oh
    • International conference on construction engineering and project management
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    • 2011.02a
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    • pp.46-51
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    • 2011
  • High-rise buildings are widely being constructed in the Middle-East, South-East, and East Asia. These buildings are usually willing to stand for the landmark of the region and, therefore, exhibit some extraordinary features such as super-tall height, elevation set-backs, overhangs, or free-form exterior surface, all of which makes the construction difficult, complex, and even unsafe at some construction stages. In addition to the elaborately planned construction sequence, prediction and monitoring of building's movement during construction and after completion are required for precise and safe construction. This is often called the Building Movement Control during construction. This study describes Building Movement Control of the KLCC Tower, a 58-story office building currently being built right next to the famous PETRONAS Twin Towers. The main items of the Building Movement Control for the KLCC Tower are axial shortening and verticality. Preliminary prediction of these items are already carried out by the structural design team but more accurate prediction based on construction stage analysis and combined with time-dependent material testing, field monitoring, and site survey is done by the main contractor. As of September 2010, the Tower is under construction at level 30, where the plan abruptly changes from rectangle to triangle. Findings and troubleshooting until the current construction stage are explained in detail and implementations are suggested for future applications.

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Induced Mutant Animal Models for Studying the Genetics of Hypertension and Atherosclerosis

  • Oh, Goo-Taeg
    • Toxicological Research
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    • v.17
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    • pp.289-292
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    • 2001
  • Gene targeting allows precise, predetermined changes to be made in a chosen gene in the mouse genome. To date, targeting has been used most often for generation of animals completely lacking the product of a gene of interest. Models of essential hypertension have been produced by mutated genes relating renin angiotensin system. The most significant contribution to understanding the genetic etiology of essential hypertension is probably the demonstration that discrete alterations in the expression of a variety of different genes can individually cause changes in the blood pressures of mice, even when the mice have all their compensatory mechanisms intact. These effects are readily detected in animals having moderate decreases in gene function due to heterozygosity for gene disruptions or modest increases due to gene duplication. As a species the mouse is highly resistant to atherosclerosis. However. through induced mutations it has been possible to develop lines oj mice that are deficient in apolipoprotein E, a ligand important in lipoprotein clearance, develop atherosclerotic lesions resembling those observed in humans. The atherosclerotic lesions in apoE-deficient mice have been well characterized, and they resemble human lesions in their sites of predilection and progression to the fibroproliferative stage. Other promising models are mice that are deficient in the low-density lipoprotein receptor. Considerable work still remains to be done in dissecting out in a rigorous manner the effects of alterations in single genes on the induction or progression of atherosclerosis and on the control of blood pressures. Perhaps even more exciting is the opportunity now becoming available to breed animals in which the effects oj precise differences in more than one gene can be studied in combination.

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Dynamic-Elastic Deformation Analysis for Precise Design of High Speed Press Machine (동적 탄성 변형 해석을 통한 고속프레스 정밀도 분석)

  • Kim, Heung-Kyu;Jung, Chul Jae;Cho, Chongdu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.1
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    • pp.79-88
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    • 2014
  • Enhancing the working speed and positional accuracy of high-speed press machines is essential for improving the parts accuracy and productivity. However it is known that the positional accuracy decreases and the risk of parts failure increases as the working speed of press machine increases. Therefore predicting such problems during the stage of press structure design is necessary for precise design of high-speed press machines. In the present investigation, the dynamic-elastic deformation of press drive module parts with eccentric masses was examined by finite element analysis and experiment. Then the positional accuracy and parts failure of high-speed press machines was evaluated.

Selection of Main Factors by Experimental Analysis for Profile Blast Machining Based on Microparticle Blasting Equipment with a Two-Axis Sequence Control Stage (2축 시퀀스 제어 스테이지와 미세입자 분사장치에 의한 형상 분사가공시 실험계획법에 의한 주요인자 검출)

  • Hwang, Chul-Woong;Lee, Sea-Han;Wang, Duck Hyun
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.19 no.11
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    • pp.64-69
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    • 2020
  • To determine the effective factors for microparticle blasting with precise sequence position control in the x-axis and y-axis directions, we conducted a statistical experimental analysis of blasted square shapes by considering five condition factors. The control input and output were operated simultaneously by rotation-linear motion conversion and fine particles were blasted onto the aluminum specimen by precise position control driving using multiple execution codes. The micro-driving device used for processing was capable of microparticle blasting and of controlling the system through contact with a limit sensor at high speed and a two-degree-of-freedom driving mechanism. Our experiments were conducted on 1,050 specimens of pure aluminum (containing <1% of other elements). The effects of several factors (e.g., particle and nozzle diameters, blasting pressure, and federate and blasting cycle numbers) on the surface roughness and blasted surface's depth were verified through a statistical experimental analysis by applying the dispersion analysis method. This statistical analysis revealed that the nozzle diameter, the blasting pressure, and the blasting cycle number were the dominant factors.

Precise dynamic finite element elastic-plastic seismic analysis considering welds for nuclear power plants

  • Kim, Jong-Sung;Jang, Hyun-Su
    • Nuclear Engineering and Technology
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    • v.54 no.7
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    • pp.2550-2563
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    • 2022
  • This study performed a precise dynamic finite element time history elastic-plastic seismic analysis considering the welds, which have been not considered in design stage, on the nuclear components subjected to severe seismic loadings such as beyond-design basis earthquakes for sustainable nuclear power plants. First, the dynamic finite element elastic-plastic seismic analysis was performed for a general design practice that does not take into account the welds of the pressurizer surge line system, one of safety class I components in nuclear power plants, and then the reference values for the accumulated equivalent plastic strain, equivalent plastic strain, and von Mises effective stress were set. Second, the dynamic finite element elastic-plastic seismic analyses were performed for the case of considering only the mechanical strength over-mismatch of the welds as well as for the case of considering both the strength over-mismatch and welding residual strain. Third, the effects of the strength over-mismatch and welding residual strain were analyzed by comparing the finite element analysis results with the reference values. As a result of the comparison, it was found that not considering the strength over-mismatch may lead to conservative assessment results, whereas not considering the welding residual strain may be non-conservative.

Calibration Technology for Precise Alignment of Large Flat Panel Displays (대형 평판 디스플레이의 정밀 정렬을 위한 캘리브레이션 기술)

  • Hong, Jun-Ho;Shin, Dongwon
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.21 no.3
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    • pp.100-109
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    • 2022
  • In this study, calibration technology that increases the alignment accuracy in large flexible flat panels was studied. For precise of calibration, a systematization of the calibration algorithm was established, and a calibration correction technique was studied to revise calibration errors. A coordinate systems of camera and UVW stage was established to get the global position of the mark, and equations for translational and rotational calibration were systematically derived based on geometrical analysis. Correction process for the calibration data was carried, and alignment experiments were performed sequentially in cases of the presence or absence of calibration-correction. Alignment results of both calibration correction and non-calibration correction showed accuracy performance less than 1㎛. On the other hand, the standard deviation in calibration-correction is smaller than non-calibration correction. Therefore, calibration correction showed improvement of the alignment repeatability.

The Variation of Yield-Related Traits of the QTL Pyramiding Lines for Climate-resilience and Nutrition Uptake in Rice

  • Joong Hyoun Chin
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.14-14
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    • 2022
  • Greenhouse gas emissions are one of the critical factors that drive change in rice cropping systems. Within this changing system, less water irrigation and chemical fertilizer are seriously considered, as well combining precision farming technologies with irrigation control. Water and phosphorus (P) fertilizer are two of the most critical inputs in rice cultivation. Due to the lack of water availability in the system, P fertilizer is not available, especially in acidic soil conditions. Moreover, the various types of abiotic stresses, such as drought, high temperature, salinity, submergence, and limited fertilizer result in significant yield loss in the system. Even in the late stage of growth, the waves caused by diseases and insects make the field more unfruitful. Therefore, agronomists and breeders need to identify the secondary phenotypes to estimate the yield loss of when stress appears. The prediction will be clearer if we have a set of markers tagging the causal variation and the associated precise phenotype indices. Although there have been various studies for abiotic stress tolerance, we still lack functional molecular markers and phenotype indices. This is due to the underlying challenges caused by environmental factors in highly unpredictable regional and yearly environmental conditions in the field system. Pupl (phosphorus uptake 1) is still known as the first QTL associated with phosphorus uptake and have been validated in different field crops. Interestingly, some pyramiding lines of Pupl and other QTLs for other stress tolerances showed preferable phenotypes in the yield. Precise physiological studies with the help of genomics are on-going and some results will be discussed.

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A Study on the Improvement of Maintaining Temperature of Aviation Dangerous Goods (항공 운송 위험물의 정온 유지 개선방안)

  • Se-Cheol Shin;Hyung-Hwan An
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.6_3
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    • pp.1215-1221
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    • 2023
  • According to the study and experiments performed on the Improvement of Maintaining Temperature of Aviation Dangerous Goods, a conclusion was drawn that clear technical guidelines should be established from the design and assembly stage of temperature-controlled packaging, taking into account actual transportation environment. In particular, profiles consisting of only two types of summer and winter are difficult to adjust flexibly in transportation process with severe weather and temperature changes such as spring and fall. To this end, there is a need to establish a compromise profile configuration for summer and winter. It was also found that the condition of the refrigerant, temperature control, and the speed of the packaging operation have a significant impact on maintaining constant temperature. Therefore, all packing operations need to be completed within a short period of time in the environment close to the target temperature. The current packing instructions provided by packaging manufacturers do not provide precise instructions on post-conditioning, but the experiments in this study confirmed that post-conditioning is very important for maintaining the target temperature, so it is necessary to provide precise legal packing technical instructions.