• 대한물리치료과학회지
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• 제9권2호
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• pp.37-48
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• 2002

The purpose of this study is to improve the effect of Lumbar extensor exercise program and develop the Lumbar extensor exercise program which will be suitable to the patients characteristics. In this study the experimental group was made up of 38 subjects. They are the patients with low back pain using the Lumbar extension exercise program in C hospital. The lumbar extension exercise program was given two times a week for 8 weeks. The results were estimated by Lumbar extensor strength by diagnosis agent. The results were measured three times, one time pre-treatment and two times post-treatment at 4weeks and 8weeks by lumbar extensor curve angle(0, 12, 24, 36, 48, 60, 72). The results were compared at pre-test 4weeks and 8weeks. The muscle strength measured at both 4weeks and 8weeks with the greater strength was shown at 4weeks. The muscle strength of patients with M.strain, Laminectomy and HNP was increased at all angles except for patients with stenosis. The results of this study indicated that diagnosis influenced the muscle strength in Lumbar extensor exercise program.

• 열처리공학회지
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• 제20권4호
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• pp.181-186
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• 2007

Effect of heat treatment conditions on formability and property of warm hydroformed parts for Al 6061 extruded tubes was investigated in this study. For the investigation, as-extruded, fully annealed and T6-treated Al 6061 seamless tubes were prepared. To evaluate the warm hydroformability, uni-axial tensile test and free bulge test were performed at various pre- and post-heat treatment conditions. And the tensile test specimens were obtained from hexagonal prototype hydroformed parts at $250^{\circ}C$. As a result, hydroformability of fully annealed tube is 25% higher than that of extruded tube. The tensile strength and strain of hydroformed part reach to 330 MPa and 12%, respectively, when the part was T6 treated after warm hydroforming. However, the hydroformability of T6 pre-treated tube is relatively low due to the decreased elongation, 8%.

• 한국정밀공학회지
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• 제27권2호
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• pp.153-159
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• 2010

Recently, it has been reported that mechanical stimulation takes a role in improving cell growth. Also, became generally known that skeletal system as bone or cartilage tissues take influence of compression loading. In this study, we fabricated a custom-made bioreactor and analyzed that conditions of compressive loading would influence cell growth. To compare the effect of intermittent compressive loading on cell-encapsulated agarose scaffold, we cultured preosteoblast cell (MC3T3-E1 cells) statically and dynamically. And dynamic culture conditions were produced by changing parameters such as the iteration time and interval delay time. Also, cellencapsulated agarose scaffold were subjected to 10 % dynamic compressive strain at 1㎐ frequency for 7 days. After cell culture, cell proliferation was assessed with PI stain assay for fluorescence images and flow cytometry (FACS).

• 열처리공학회지
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• 제13권2호
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• pp.91-97
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• 2000

The structure and mechanical properties of TiN and TiCN thin films deposited on STD61 steel substrates by the RF-sputtering methods has been studied by using XPS, XRD, micro-hardness tester, scratch tester, and wear-resistance tester. XPS results showed that the TiCN thin film formed with chemical bonding state. The TiN thin films grew with (111) orientation having the lowest strain energy by compressive stress, whereas the TiCN thin films grew with both (111) and (200) orientation, but (200) orientation having the lowest surface energy becomes dominant as carbon contents increase. The pre-etching treatment of substrate did not affect on the preferred orientation of thin films, but it played an important role in improving mechanical properties of thin films such as the hardness, adhesion and wear- resistance. Especially, the TiCN thin films showed the superior wear resistances due to high hardness and low friction coefficient compared with TiN thin films.

• 지질공학
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• 제12권4호
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• pp.459-469
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• 2002

재성형된 해성점토 시료를 연직·수평방향으로 채취하여 표준압밀시험(SCT)과 일정변형률속도 압밀시험(CRSC)을 실시하여 연약 해성점토지반에 대한 압밀정수들의 구성관계를 확인하였다. 또한, 불교란 교란 화강암질 풍화토의 표준·일정변형률속도 압밀시험을 통하여 화강암질 풍화토에 대한 압밀 정수들의 특성과 적용성을 고찰하였다. 그 결과 해성점토 시료의 연직·수평방향과 표준·일정변형률속도압밀시험 방법에 따라 선행압밀응력, 압축지수, 과잉간극수압, 간극수압비 등이 달리 산정됨을 알 수 있었다. 또한, 불교란·교란 화강암질 풍화토 시료에서도 해성점토와 유사하게 과압밑·정규압밀 구간에서 압밀정수들의 변화를 확인하였다.

• Steel and Composite Structures
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• 제30권4호
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• pp.351-364
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• 2019

Earthquake and fire are both severe disasters for building structures. Since earthquake-induced damage will weaken the structure and reduce its fire endurance, it is important to investigate the behavior of structure subjected to post-earthquake fire. In this paper, steel-concrete composite beam-to-column joints were tested under fire with pre-damage caused by cyclic loads. Beforehand, three control specimens with no pre-damage were tested to capture the static, cyclic and fire-resistant performance of intact joints. Experimental data including strain, deflection and temperature recorded at several points are presented and analyzed to quantify the influence of cyclic damage on fire resistance. It is indicated that the fire endurance of damaged joints decreased with the increase of damage level, mainly due to faster heating-up rate after cyclic damage. However, cracks induced by cyclic loading in concrete are found to mitigate the concrete spalling at elevated temperatures. Moreover, the relationship between fire resistance and damage degree is revealed from experimental results, which can be applied in fire safety design and is worthwhile for further research.

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 2004년도 Annual Meeting BioExibition International Symposium
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• pp.60-61
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• 2004

Metabolic engineering is now a well established discipline, used extensively to determine and execute rational strategies of strain development to improve the performance of micro-organisms employed in industrial fermentations. The basic principle of this approach is that performance of the microbial catalyst should be adequately characterised metabolically so as to clearlyidentify the metabolic network constraints, thereby identifying the most probable targets for genetic engineering and the extent to which improvements can be realistically achieved. In order to harness correctly this potential, it is clear that the physiological analysis of each strain studied needs to be undertaken under conditions as close as possible to the physico-chemical environment in which the strain evolves within the full-scale process. Furthermore, this analysis needs to be undertaken throughoutthe entire fermentation so as to take into account the changing environment in an essentially dynamic situation in which metabolic stress is accentuated by the microbial activity itself, leading to increasingly important stress response at a metabolic level. All too often these industrial fermentation constraints are overlooked, leading to identification of targets whose validity within the industrial context is at best limited. Thus the conceptual error is linked to experimental design rather than inadequate methodology. New tools are becoming available which open up new possibilities in metabolic engineering and the characterisation of complex metabolic networks. Traditionally metabolic analysis was targeted towards pre-identified genes and their corresponding enzymatic activities within pre-selected metabolic pathways. Those pathways not included at the onset were intrinsically removed from the network giving a fundamentally localised vision of pathway functionality. New tools from genome research extend this reductive approach so as to include the global characteristics of a given biological model which can now be seen as an integrated functional unit rather than a specific sub-group of biochemical reactions, thereby facilitating the resolution of complexnetworks whose exact composition cannot be estimated at the onset. This global overview of whole cell physiology enables new targets to be identified which would classically not have been suspected previously. Of course, as with all powerful analytical tools, post-genomic technology must be used carefully so as to avoid expensive errors. This is not always the case and the data obtained need to be examined carefully to avoid embarking on the study of artefacts due to poor understanding of cell biology. These basic developments and the underlying concepts will be illustrated with examples from the author's laboratory concerning the industrial production of commodity chemicals using a number of industrially important bacteria. The different levels of possibleinvestigation and the extent to which the data can be extrapolated will be highlighted together with the extent to which realistic yield targets can be attained. Genetic engineering strategies and the performance of the resulting strains will be examined within the context of the prevailing experimental conditions encountered in the industrial fermentor. Examples used will include the production of amino acids, vitamins and polysaccharides. In each case metabolic constraints can be identified and the extent to which performance can be enhanced predicted

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.250-254
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• 2002

Intergranular corrosion of austenitic stainless steels is a conventional and momentous problem during welding and high temperature use. One of the major reasons for such intergranular corrosion is so-called sensitization, i.e., chromium depletion due to chromium carbide precipitation at grain boundaries. Conventional methods for preventing sensitization of austenitic stainless steels include reduction of carbon content in the material, stabilization of carbon atoms as non-chromium carbides by the addition of titanium, niobium or zirconium, local solution-heat-treatment by laser beam, etc. These methods, however, are not without drawbacks. Recent grain boundary structure studies have demonstrated that grain boundary phenomena strongly depend on the crystallographic nature and atomic structure of the grain boundary, and that grain boundaries with coincidence site lattices are immune to intergranular corrosion. The concept of "grain boundary design and control", which involves a desirable grain boundary character distribution, has been developed as grain boundary engineering. The feasibility of grain boundary engineering has been demonstrated mainly by thermomechanical treatments. In the present study, a thermomechanical treatment was tried to improve the resistance to the sensitization by grain boundary engineering. A type 304 austenitic stainless steel was pre-strained and heat-treated, and then sensitized, varying the parameters (pre-strain, temperature, time, etc.) during the thermomechanical treatment. The grain boundary character distribution was examined by orientation imaging microscopy. The intergranular corrosion resistance was evaluated by electrochemical potentiokinetic reactivation and ferric sulfate-sulfuric acid tests. The sensitivity to intergranular corrosion was reduced by the thermomechanical treatment and indicated a minimum at a small roll-reduction. The frequency of coincidence-site-lattice boundaries indicated a maximum at a small strain. The ferric sulfate-sulfuric acid test showed much smaller corrosion rate in the thermomechanically-treated specimen than in the base material. An excellent intergranular corrosion resistance was obtained by a small strain annealing at a relatively low temperature for long time. The optimum parameters created a uniform distribution of a high frequency of coincidence site lattice boundaries in the specimen where corrosive random boundaries were isolated. The results suggest that the thermomechanical treatment can introduce low energy segments in the grain boundary network by annealing twins and can arrest the percolation of intergranular corrosion from the surface.

• 한국지반공학회논문집
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• 제28권8호
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• pp.5-19
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• 2012

준설매립지반 설계시 압밀 소요시간 단축을 위해 연직배수공법와 선행재하공법등의 연약지반 개량공법을 주로 적용한다. 준설매립지반의 자중에 의한 압밀이 완료되기까지는 많은 시간이 소요되므로 공사비 절감, 공기단축의 이유로 연약지반 개량공법은 일반적으로 자중압밀 도중 적용된다. 본 논문에서는 준설매립지반에서 연직방향으로 자중압밀이 진행되는 도중 연직배수재 타설에 의해 방사방향의 흐름이 추가로 발생하는 경우의 압밀거동 예측을 위하여 자중압밀을 고려한 2차원 축대칭 비선형 유한변형 압밀 지배방정식과 이를 적용하기 위한 수치모델(Axi-Selcon)을 개발하였다. Axi-Selcon의 검증과 자중압밀 도중 연직배수재가 타설된 준설매립지반을 모사하기 위해 일련의 실내시험을 수행하였다. 이를 위해 연직배수재가 타설된 준설매립지반을 모사하는 대형자중압밀 시험기를 고안하였다. 모델의 추가적인 검증을 위하여 기존에 제안된 간편 해석법을 적용한 결과와 Axi-Selcon의 해석결과와 비교하였다. 마지막으로, Axi-Selcon을 적용하여 가상의 대심도 준설매립지반의 거동을 예측하였다. 이와 같은 일련의 모델 검증과정을 통해 본 논문에서 개발된 Axi-Selcon은 자중압밀 도중 연직배수재 타설과 선행재하공법이 적용될 경우에 대한 초연약 준설매립지반의 압밀 거동을 적절히 예측할 수 있음을 보였다.

• 한국해양환경ㆍ에너지학회지
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• 제7권3호
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• pp.146-151
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• 2004

포접력을 지닌 2-hydroxypropyl-β-cyclodextrin(β-HPCD)을 비롯한 cyclodextrin계 화합물은 소수성 유기물질의 용해도를 증가시킴으로써 미생물에 의한 분해를 촉진시키나 그 외의 자세한 기작은 알려져 있지 않다. 본 실험에서는 β-HPCD 유무에 따라 고분자 PAHs 분해력을 지닌 Novosphingobium pentaromtivorans US6-1 균주의 pyrene라 benzo[a]pyrene(B[a]P)의 분해정도, 이때의 biomass 변화 및 dioxygenase활성을 측정함으로써 PAHs 생분해과정에서 β-HPCD의 역할을 규명하고자 하였다. 실험구는 균주와 PAHs, β-HPCD의 존재 유무에 따라 8개 조건으로 준비하였으며 각 실험구의 배양기간에 따른 PAHs 분해도와 생체량의 변화를 측정하였다. Pyrene의 경우 β-HPCD가 존재함에 따라 분해도가 증진되는 것이 확인되었으며, 특히 B[a]P의 분해에는 β-HPCD가 필수요소로 작용하였다. 생체량의 변화는 PAHs의 존재 유무에 영향을 받지 않았고 β-HPCD의 존재 유무에 따라 차이를 나타내었다. 또한 US6-1 균주는 β-HPCD가 포함된 MM2 무기영양배지에서 전배양 할 때에 ZoBell 배지에서 전배양하는 경우에 비해 catechol-1,2-dioxygenase 효소활성이 높은 것으로 나타났으나 그 값은 빈영양상태에서 배양한 세포의 효소환성과 큰 차이를 보이지는 않았다. 이상의 결과로 볼 때 β-HPCD는 PAHs의 이용성을 높여주는 동시에 탄소원으로 이용되어 균주의 생체량 증가에 기여함으로써 PAMs의 분해력을 증진시키지만 dioxygenase 효소활성에는 영향을 미치지 않는 것으로 사료된다.