• 제목/요약/키워드: pre-feasibility evaluation

검색결과 45건 처리시간 0.025초

Evaluation of Computer-Assisted Quantitative Volumetric Analysis for Pre-Operative Resectability Assessment of Huge Hepatocellular Carcinoma

  • Tang, Jian-Hua;Yan, Fu-Hua;Zhou, Mei-Ling;Xu, Peng-Ju;Zhou, Jian;Fan, Jia
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제14권5호
    • /
    • pp.3045-3050
    • /
    • 2013
  • Purpose: Hepatic resection is arguably the preferred treatment for huge hepatocellular carcinoma (H-HCC). Estimating the remnant liver volume is therefore essential. This study aimed to evaluate the feasibility of using computer-assisted volumetric analysis for this purpose. Methods: The study involved 40 patients with H-HCC. Laboratory examinations were conducted, and a contrast CT-scan revealed that 30 cases out of the participating 40 had single-lesion tumors. The remaining 10 had less than three satellite tumors. With the consensus of the team, two physicians conducted computer-assisted 3D segmentation of the liver, tumor, and vessels in each case. Volume was automatically computed from each segmented/labeled anatomical field. To estimate the resection volume, virtual lobectomy was applied to the main tumor. A margin greater than 1 cm was applied to the satellite tumors. Resectability was predicted by computing a ratio of functional liver resection (R) as (Vresected-Vtumor)/(Vtotal-Vtumor) x 100%, applying a threshold of 50% and 60% for cirrhotic and non-cirrhotic cases, respectively. This estimation was then compared with surgical findings. Results: Out of the 22 patients who had undergone hepatectomies, only one had an R that exceeded the threshold. Among the remaining 18 patients with non-resectable H-HCC, 12 had Rs that exceeded the specified ratio and the remaining 6 had Rs that were < 50%. Four of the patients who had Rs less than 50% underwent incomplete surgery due to operative findings of more extensive satellite tumors, vascular invasion, or metastasis. The other two cases did not undergo surgery because of the high risk involved in removing the tumor. Overall, the ratio of functional liver resection for estimating resectability correlated well with the other surgical findings. Conclusion: Efficient pre-operative resectability assessment of H-HCC using computer-assisted volumetric analysis is feasible.

중소기업의 기술력평가를 통한 신용등급 상향의 타당성 연구 (Feasibility Study of Credit Rating Upgrading through Technology Evaluation of SMEs)

  • 김재천;손석현
    • 기술혁신연구
    • /
    • 제26권2호
    • /
    • pp.129-149
    • /
    • 2018
  • 기술금융은 금융당국이 금융산업 선진화, 중소기업발전을 위해 강력한 정책적 의지를 가지고 도입하여 시행하고 있는 분야이다. 이러한 배경으로 은행의 자체적인 기술평가가 2016년 9월부터 시행되었다. 기술우수기업은 기술평가과정에서 산출된 높은 기술등급으로 기존 신용등급이 상향되게 되며, 결과적으로 높아진 신용등급만큼 금융거래시 혜택을 받게 된다. 분석대상은 KEB하나은행이 2016년 9월부터 2017년 하반기까지 수행한 기술평가 대상 2,719개 업체를 분석하였다. 2016년 하반기 수행된 406개 업체에 대한 기술력평가 예비 연구에서 기존 신용등급과 산출된 기술등급을 결합한 결과, J58'출판업'의 기술신용등급은 신용등급대비 1.05등급 상향되어 상향정도가 가장 높았으며, C10'식료품 제조업'이 두 번째로 상향정도가 높았다. 이로써 기술력평가를 통한 수혜업종을 가려낼 수 있었으며, 업종별 기술 평가의 유용성을 확인할 수 있었다. 이에, 전체 수행기간동안 평가된 2,719개 업체에 대하여 기술력, 업력, 성장유망업종별 분석을 수행하였다. 분석결과 기술력 T-4이상 등급 업체들의 신용등급 상향정도가 가장 높았으며 5년 기준 업력에 따른 기술력평가의 유효성은 미미한 것으로 파악되었다. 정책지원의 효율성차원에서 지정된 성장유망업종에 해당하는 업체들을 대상으로 분석한 결과 일반기업대비 신용등급의 상향정도가 높아 성장유망업종 지원의 유용성을 확인할 수 있었다. 향후, 은행의 업체 발굴 또는 당국의 정책수립시에 T-4이상의 기술력 우수기업, 성장유망 업종에 집중하면 자금지원 효과를 극대화할 수 있을 것으로 판단된다.

RETScreen를 활용한 풍력발전사업의 투자 적절성 평가 사례 연구 (A Study on the Feasibility Evaluation of Overseas Wind Power Projects with RETScreen Software)

  • 이주수;최봉석;이화수;전의찬
    • 한국기후변화학회지
    • /
    • 제4권2호
    • /
    • pp.105-114
    • /
    • 2013
  • 우리나라의 해외투자는 현지 자본시장에 투자하는 방법에서, 현지에 회사를 설립하여 운용하는 해외직접투자로 바뀌고 있다. 해외직접투자는 다양한 동기에서 이루어지며, 신 재생에너지 사업에 대한 해외직접투자 또한 다양한 각도에서 검토되고 있다. 국내 기업은 해외의 신 재생에너지 사업에 대한 진출을 통하여 장비의 수출, 건설공사 수주, 프로젝트 관리기술의 습득 및 시장선점의 효과를 누릴 수 있다. 또한, 투자수익을 향유할 수도 있다. 이러한 이유에서 신 재생에너지 사업 중 시장규모가 가장 큰 풍력발전을 대상으로 중국, 미국, 독일, 영국 등 해외 4개 국가의 풍력발전사업에 투자한다고 가정하여 각 국가의 전력단가, 인플레이션율, 법인세율, 부채조달이자율 등이 수익률에 미치는 영향을 비교분석하였다. 분석 결과, 전력판매단가가 가장 높은 독일의 경우가 수익률이 가장 높았으며, 개별적인 요인 중 각 국가의 전력판매단가와 부채이자율이 수익률에 중요한 영향을 미치는 것으로 나타났다. 이러한 분석방법이 향후 풍력발전사업에 대한 해외 직접투자시 적절한 투자의 사결정을 하는데 도움이 될 것으로 판단된다.

가상 건설 시스템 비전과 구축 방향 (A vision and strategy for developing virtual construction system)

  • 최철호;진상윤;김재준;신현목;이광명;윤수원
    • 한국전산구조공학회:학술대회논문집
    • /
    • 한국전산구조공학회 2007년도 정기 학술대회 논문집
    • /
    • pp.62-67
    • /
    • 2007
  • The research team for the virtual construction development was established with the support of Korea Ministry of Construction and Transportation, and KICTEP (Korea Institute of Construction and Transportation Technology Evaluation and Planning). Its aims are to develop system that is to improve productivity & quality, to create a higher value-added business, and to cultivate international competitiveness in the construction industry. The virtual construction system is a design, engineering, and construction management information system that allows the project participants to effectively share the information throughout the construction life cycle with the support of 3D and design information. To achieve this, the research team focuses on developing several systems. First, the team focuses on developing for the pre-planning, the structural engineering, MEP, and the 3D based estimation system. Second, they focus on developing a simulation system for the construction process planning and feasibility study with help of the virtual reality technologies. Third, they focus on developing the CPLM (Construction Project Life-cycle Management) system for managing construction project data, and the decision support system that makes the collaboration among the project participants based on 3D technologies and information. We also focus on developing the SDAI (Standard Data Access Interface), the localized guideline for 3D design, and a training program. In addition, we focus on developing the undeveloped area of the commercial system and building an environment that can support the communication and collaboration in the construction life-cycle rather than developing the existing and commercialized system.

  • PDF

Percutaneous Ultrasound-Guided Fine-Needle Aspiration Cytology and Core-Needle Biopsy for Laryngeal and Hypopharyngeal Masses

  • Dongbin Ahn;Gil Joon Lee;Jin Ho Sohn;Jeong Eun Lee
    • Korean Journal of Radiology
    • /
    • 제22권4호
    • /
    • pp.596-603
    • /
    • 2021
  • Objective: To evaluate the feasibility and diagnostic performance of ultrasound (US)-guided fine-needle aspiration cytology and core-needle biopsy (US-FNAC/CNB) for the diagnosis of laryngo-hypopharyngeal masses. Materials and Methods: This was a single-center prospective case series. From January 2018 to June 2019, we initially enrolled 40 patients with highly suspicious laryngo-hypopharyngeal masses on laryngoscopic examinations. Of these, 28 patients with the mass involving or abutting the pre-epiglottic, paraglottic, pyriform sinus, and/or subglottic regions were finally included. These patients underwent US examinations with/without subsequent US-FNAC/CNB under local anesthesia for evaluation of the laryngo-hypopharyngeal mass. Results: Of the 28 patients who underwent US examinations, a laryngo-hypopharyngeal mass was identified in 26 patients (92.9%). US-FNAC/CNB was performed successfully in 25 of these patients (96.2%), while the procedure failed to target the mass in 1 patient (3.8%). The performance of US caused minor subclinical hematoma in 2 patients (7.7%), but no major complications occurred. US-FNAC/CNB yielded conclusive results in 24 (96.0%) out of the 25 patients with a successful procedure, including 23 patients with squamous cell carcinoma (SCC) and 1 patient with a benign mass. In one patient with atypical cells in US-FNAC, additional direct laryngoscopic biopsy (DLB) was required to confirm SCC. Among the 26 patients who received US-FNAC/CNB, the time from first visit to pathological diagnosis was 7.8 days. For 24 patients finally diagnosed with SCC, the time from first visit to the initiation of treatment was 25.2 days. The mean costs associated with US-FNAC/CNB was $272 under the Korean National Health Insurance Service System. Conclusion: US-FNAC/CNB for a laryngo-hypopharyngeal mass is technically feasible in selected patients, providing good diagnostic performance. This technique could be used as a first-line diagnostic modality by adopting appropriate indications to avoid general anesthesia and DLB-related complications.

MCJ를 이용한 공항서비스 품질지수 평가에 관한 연구 (A Study on the Evaluation of Service Quality Index for International Airport Using MCJ)

  • 이승창;이강석
    • 대한교통학회지
    • /
    • 제23권1호
    • /
    • pp.45-54
    • /
    • 2005
  • 본 연구의 목적은 국제공항의 주요 서비스 항목별 중요도(importance), 이용자의 지각수준(perceived level), 다양한 평가방법(complex index)등을 활용한 주관적 및 객관적 측정 척도를 개발하고자 하며 공항서비스 질에 대한 기준 설정, 주요개선 사항의 발견 및 조치평가 등을 체계적으로 할 수 있는 내부관리용 옴니버스 모니터링 시스템 (OMS : Omnibus Monitoring System)의 개발이다. 이는 국제공항의 주요 서비스 평가를 위한 계량적 분석 도구의 개발과 2차 계량 지료(quantitative Secondary data)활용, 공항이용자에 대한 설문으로 지각된 자료(perceived data)분석, 자료수집-입력-분석 과정의 시스템화, 결과물의 그래픽화에 따른 데이터이미지화, 서비스인카운터(service encounter)계획 및 통제 기능 부여, 국제적 기준을 최저로 경쟁력을 확보하려는 것이다. 또한, 지표의 개발을 위해서 기존의 외국문헌 및 국제공항의 실사에 기초한 사전조사 계획의 수립과 실행이 중요하기에 준비된 사전조사의 결과를 토대로 출국자, 입국자, 상주근문자 등의 주관적 측정정도를 개발하고 보완적인 수단으로써 객관적 지표의 연구가 동시에 이루어졌다. 이러한 절차로 개발된 평가척도의 신뢰성 및 타당성을 실증적, 통계적으로 확보하고, 공항 서비스 척도의 효율적인 운영을 위한 소프트웨어 시스템을 개발함으로써 정규, 비정규적인 공항서비스의 모니터링이 가능하도록 연구가 진행되었다.

Effects of Remote Ischemic Pre-Conditioning to Prevent Contrast-Induced Nephropathy after Intravenous Contrast Medium Injection: A Randomized Controlled Trial

  • Dihia Belabbas;Caroline Koch;Segolene Chaudru;Mathieu Lederlin;Bruno Laviolle;Estelle Le Pabic;Dominique Boulmier;Jean-Francois Heautot;Guillaume Mahe
    • Korean Journal of Radiology
    • /
    • 제21권11호
    • /
    • pp.1230-1238
    • /
    • 2020
  • Objective: We aimed to assess the effects of remote ischemic pre-conditioning (RIPC) on the incidence of contrast-induced nephropathy (CIN) after an intravenous (IV) or intra-arterial injection of contrast medium (CM) in patient and control groups. Materials and Methods: This prospective, randomized, single-blinded, controlled trial included 26 patients who were hospitalized for the evaluation of the feasibility of transcatheter aortic valve implantation and underwent investigations including contrast-enhanced computed tomography (CT), with Mehran risk scores greater than or equal to six. All the patients underwent four cycles of five minute-blood pressure cuff inflation followed by five minutes of total deflation. In the RIPC group (n = 13), the cuff was inflated to 50 mm Hg above the patient's systolic blood pressure (SBP); in the control group (n = 13), it was inflated to 10 mm Hg below the patient's SBP. The primary endpoint was the occurrence of CIN. Additionally, variation in the serum levels of cystatin C was assessed. Results: One case of CIN was observed in the control group, whereas no cases were detected in the RIPC group (p = 0.48, analysis of 25 patients). Mean creatinine values at the baseline, 24 hours after injection of CM, and 48 hours after injection of CM were 88 ± 32 μmol/L, 91 ± 28 μmol/L and 82 ± 29 μmol/L, respectively (p = 0.73) in the RIPC group, whereas in the control group, they were 100 ± 36 μmol/L, 110 ± 36 μmol/L, and 105 ± 34 μmol/L, respectively (p = 0.78). Cystatin C values (median [Q1, Q3]) at the baseline, 24 hours after injection of CM, and 48 hours after injection of CM were 1.10 [1.08, 1.18] mg/L, 1.17 [0.97, 1.35] mg/L, and 1.12 [0.99, 1.24] mg/L, respectively (p = 0.88) in the RIPC group, whereas they were 1.11 [0.97, 1.28] mg/L, 1.13 [1.08, 1.25] mg/L, and 1.16 [1.03, 1.31] mg/L, respectively (p = 0.93), in the control group. Conclusion: The risk of CIN after an IV injection of CM is very low in patients with Mehran risk score greater than or equal to six and even in the patients who are unable to receive preventive hyperhydration. Hence, the Mehran risk score may not be an appropriate method for the estimation of the risk of CIN after IV CM injection.

Development and Evaluation of a Patient-Reported Outcome (PRO) Scale for Breast Cancer

  • Zhang, Jun;Yao, Yu-Feng;Zha, Xiao-Ming;Pan, Li-Qun;Bian, Wei-He;Tang, Jin Hai
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제16권18호
    • /
    • pp.8573-8578
    • /
    • 2016
  • Background: This study was guided by principles of the theoretical system of evidence-based medicine. In particular, when searching for evidence of breast cancer, a measuring scale is an instrument for evaluating curative effects in accordance with the laws and characteristics of medicine and exploring the establishment of a system for medically assessing curative effects. At present, there exist few tools for evaluating curative effects. Patient-reported outcomes (PROs) refer to outcomes directly reported by patients (without input or explanations from doctors or other intermediaries) with respect to all aspects of their health. Data obtained from PROs provide evidence of treatment effects. Materials and Methods: In accordance with the tenets of theoretical medicine and ancient medical theory regarding breast cancer, principles for developing a PRO scale were established, and a theoretical model was developed and a literature review was performed, items from this pool were combined and split, and an initial scale was constructed. After a pilot survey and additional modifications, a pre-questionnaire scale was formed and used in a field investigation. After the application of statistical methods, the item pool was used to create a formal scale. The reliability, validity and feasibility of this formal scale were then assessed. Results: In a clinical investigation, 479 responses were recovered, with an acceptance rate of 95%. a combination of various methods was employed, and the items that were selected by all methods or more than half of the methods were employed in the questionnaire. In these cases, the screening methods were combined with certain features of the item, A total of four domains and 38 items were reserved. The reliability analysis indicated that the PRO scale was relatively reliable. Conclusions: Scientific assessment proved that the proposed scale exhibited good reliability and validity. This scale was readily accepted and could be used to assess the curative effects of medical therapy. However, given the limited scope of this investigation, the capacity for adapting this scale to incorporate other theories could not be determined.

신속한 이탈리안라이그라스 사일리지의 품질평가를 위한 소형 근적외선분광기(NIRS)의 현장 적용성 평가 (Evaluation of Field Application of Portable Near Infrared Reflectance Spectrometer (NIRS) for Quality Evaluation of Italian Ryegrass Silages)

  • 박형수;이상훈;김종근;최기춘;서성;김원호;이효원;임영철
    • 한국초지조사료학회지
    • /
    • 제31권4호
    • /
    • pp.415-422
    • /
    • 2011
  • 본 연구는 최근 조사료의 신속한 품질평가 방법으로 근적외선 분광법의 이용성이 확대되고 있는 시점에 근적외선 분광기의 현장 적용성을 평가하기 위하여 수행되었다. 실험실용 근적외선분광기와 소형 근적외선분광기의 조사료 품질평가의 예측 정확성을 평가하기 위하여 전남지역에서 이탈리안 라이그라스 사일리지 67점을 수집하여 각각의 근적외선 분광기를 이용하여 스펙트럼을 측정한 후 사료가치의 실험실 분석값과 다변량회귀분석을 통하여 검량식을 유도하여 예측 정확성을 평가하였다. 이탈리안 라이그라스 사일리지의 수분함량에 대한 예측정확성은 실험실용 근적외선분광기와 소형근적외선분광기에서 각각 SEC = 2.50% ($R^2$=0.96), SEC = 2.83% ($R^2$=0.95)로 매우 신뢰성이 우수한 결과를 나타내었으나 사일리지의 발효품질의 주요 평가항목인 pH와 젖산함량은 실험실용 근적외선분광기의 결과가 SEC = 0.21% ($R^2$=0.82), SEC = 0.24% ($R^2$=0.83)로 소형 근적외선분광기 보다 우수한 결과를 나타내었다. 또한 ADF, NDF 및 조단백질 함량은 실험실용 근적외선분광기의 예측 정확성이 각각 SEC = 0.59% ($R^2$=0.96), SEC = 0.74% ($R^2$=0.97), SEC = 0.67% ($R^2$=0.82)로 높게 나타났다.

가정간호 서비스 질 평가를 위한 도구개발연구 (A basic research for evaluation of a Home Care Nursing Delivery System)

  • 김모임;조원정;김의숙;김성규;장순복;유호신
    • 가정∙방문간호학회지
    • /
    • 제6권
    • /
    • pp.33-45
    • /
    • 1999
  • The purpose of this study was to develop a basic framework and criteria for evaluation of quality care provided to patients with the attributes of disease in the home care nursing field, and to provide measurement tools for home health care in the future. The study design was a developmental study for evaluation of hospital-based HCN(home care nursing) in Korea. The study process was as follows: a home care nursing study team of College of Nursing. Yonsei University reviewed the nursing records of 47 patients who were enrolled at Yonsei University Medical Center Home Care Center in March, 1995. Twenty-five patients were insured at that time, were selected from 47 patients receiving home care service for study feasibility with six disease groups; Caesarean Section (C/S), simple nephrectomy, Liver cirrhosis(LC), chronic obstructive pulmonary disease(COPD), Lung cancer or cerebrovascular accident(CVA). In this study, the following items were selected : First step : Preliminary study 1. Criteria and items were selected on the basis of related literature on each disease area. 2. Items were identified by home care nurses. 3. A physician in charge reviewed the criteria and content of selected items. 4. Items were revised through preliminary study offered to both HCN patients and discharged patients from the home care center. Second step : Pretest 1. To verify the content of the items, a pretest was conducted with 18 patients of which there were three patients in each of the six selected disease groups. Third step : Test of reliability and validity of tools 1. Using the collected data from 25 patients with either cis, Simple nephrectomy, LC, COPD, Lung cancer, or CVA. the final items were revised through a panel discussion among experts in medical care who were researchers, doctors, or nurses. 2. Reliability and validity of the completed tool were verified with both inpatients and HCN patients in each of field for researches. The study results are as follows: 1. Standard for discharge with HCN referral The referral standard for home care, which included criteria for discharge with HCN referral and criteria leaving the hospital were established. These were developed through content analysis from the results of an open-ended questionnaire to related doctors concerning characteristic for discharge with HCN referral for each of the disease groups. The final criteria was decided by discussion among the researchers. 2. Instrument for measurement of health statusPatient health status was measured pre and post home care by direct observation and interview with an open-ended questionnaire which consisted of 61 items based on Gorden's nursing diagnosis classification. These included seven items on health knowledge and health management, eight items on nutrition and metabolism, three items on elimination, five items on activity and exercise, seven items on perception and cognition, three items on sleep and rest, three items on self-perception, three items on role and interpersonal relations, five items on sexuality and reproduction, five items on coping and stress, four items on value and religion, three items on family. and three items on facilities and environment. 3. Instrument for measurement of self-care The instrument for self-care measurement was classified with scales according to the attributes of the disease. Each scale measured understanding level and practice level by a Yes or No scale. Understanding level was measured by interview but practice level was measured by both observation and interview. Items for self-care measurement included 14 for patients with a CVA, five for women who had a cis, ten for patients with lung cancer, 12 for patients with COPD, five for patients with a simple nephrectomy, and 11 for patients with LC. 4. Record for follow-up management This included (1) OPD visit sheet, (2) ER visit form, (3) complications problem form, (4) readmission sheet. and (5) visit note for others medical centers which included visit date, reason for visit, patient name, caregivers, sex, age, time and cost required for visit, and traffic expenses, that is, there were open-end items that investigated OPD visits, emergency room visits, the problem and solution of complications, readmissions and visits to other medical institution to measure health problems and expenditures during the follow up period. 5. Instrument to measure patients satisfaction The satisfaction measurement instrument by Reisseer(1975) was referred to for the development of a tool to measure patient home care satisfaction. The instrument was an open-ended questionnaire which consisted of 11 domains; treatment, nursing care, information, time consumption, accessibility, rapidity, treatment skill, service relevance, attitude, satisfaction factors, dissatisfaction factors, overall satisfaction about nursing care, and others. In conclusion, Five evaluation instruments were developed for home care nursing. These were (1)standard for discharge with HCN referral. (2)instrument for measurement of health status, (3)instrument for measurement of self-care. (4)record for follow-up management, and (5)instrument to measure patient satisfaction. Also, the five instruments can be used to evaluate the effectiveness of the service to assure quality. Further research is needed to increase the reliability and validity of instrument through a community-based HCN evaluation.

  • PDF