• Journal of the Korean Society of Systems Engineering
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• v.9 no.1
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• pp.55-63
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• 2013

Nuclear power plant site selection is a complex process and its successful completion is a critical milestone in the NPP development cycle. Proper siting of NPP will ensure public health and safety, environmental conservation, reduced project failure risks and a smooth NPP development process among other benefits. The objective of this paper is to demonstrate the application of systems engineering to the problem of NPP siting in Kenya. The siting process demonstrated in this paper includes stakeholder need analysis where stakeholders are identified and their needs concerning NPP site are elicited and converted into system functional requirements. A value model is then developed and potential sites iteratively subjected to three types of criteria i.e. exclusionary criteria, avoidance criteria and suitability criteria. This process is used to identify the candidate sites. An additive value model; multiple objectives Decision Analysis (MODA) is then used to calculate candidate solutions values. The site with the highest solution value score is selected. Sensitivity studies using different criterion weight sets (thereby reflecting different viewpoints) can be conducted to assess their effect on the selection of a preferred site and thereby lend additional credibility to the decision process.

• Proceedings of the Korea Contents Association Conference
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• 2005.05a
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• pp.268-272
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• 2005

The university community site can be used as a potential element to improve the recognition of the university through the satisfaction of the members of the university with using it as well as an important means for communication on the line among the members. In spite that the community site is used by the users in the twenties at university, it consists of the contents with only basic functions. Consequently it is necessary to find out the different traits of the users to make the university community site active. Therefore, this study aims at analyzing the reality of the university community site and finding out the characteristics of the university students characterized as N-generations

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.4 no.4
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• pp.353-363
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• 2006

In order to evaluate the potential radiological risks for the reuse of the site after decommissioning of nuclear facilities, a mathematical model was developed and materialized into the Microsoft $Excel{\circledR}$ spreadsheets frame. A set of input parameter values was proposed, which is useful in the preliminary risk screening step before the detailed evaluation with the site-specific data. It appeared that the screening levels calculated by the present model was agreed with the derived concentration guideline limits resulted from RESRAD Ver.6.2 and the German dose criteria for releasing a nuclear site from regulatory control.

• The Journal of Korean Academy of Prosthodontics
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• v.38 no.6
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• pp.814-820
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• 2000

Statement of Problem. Commonly used classification systems do not inform for dentists the dimension of the available bone at a potential implant site although regarding a variety of morphologic and pathophysiologic aspects using schematic graphs. However, for the implantologist the availability of bone substance is most important independent whether it concerns the jaw basis or the alveolus. Purpose of Study. The present article refers to a new evaluation form, to analyze the available bone with regard to optional immediate loading site by site. According to a new systematic implant planning concept will be presented in two case reports. Results. The feasibility of the classification for planning and documentation of immediately loaded implants is presented in two case reports. Conclusion. The factor of bone support for immediate functional stability is important in dental implantology. The new systematic implant planning helps to systematically estimate the dimension (ASCIi classification) of the alveolus site by site to evaluate the possibility of immediate loading. The Gottingen classification thus aids to determine the degree of stability that can be expected for the planned solution.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1085-1092
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• 2022

Travel distance is a parameter mainly used in the objective function of Construction Site Layout Planning (CSLP) automation models. To obtain travel distance, common approaches, such as linear distance, shortest-distance algorithm, visibility graph, and access road path, concentrate only on identifying the shortest path. However, humans do not necessarily follow one shortest path but can choose a safer and more comfortable path according to their situation within a reasonable range. Thus, paths generated by these approaches may be different from the actual paths of the workers, which may cause a decrease in the reliability of the optimized construction site layout. To solve this problem, this paper adopts reinforcement learning (RL) inspired by various concepts of cognitive science and behavioral psychology to generate a realistic path that mimics the decision-making and behavioral processes of wayfinding of workers on the construction site. To do so, in this paper, the collection of human wayfinding tendencies and the characteristics of the walking environment of construction sites are investigated and the importance of taking these into account in simulating the actual path of workers is emphasized. Furthermore, a simulation developed by mapping the identified tendencies to the reward design shows that the RL agent behaves like a real construction worker. Based on the research findings, some opportunities and challenges were proposed. This study contributes to simulating the potential path of workers based on deep RL, which can be utilized to calculate the travel distance of CSLP automation models, contributing to providing more reliable solutions.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1209-1216
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• 2022

The majority of construction site incidents occur due to a lack of hazard awareness among workers on job sites. This lack of awareness is despite mandatory construction safety training, typically in the form of written content (safety manuals) or of images depicting hazards. To reduce job-site injuries and fatalities, general contractors have started adopting Virtual Reality (VR) to impart safety training to job site personnel. VR safety training can take the form of an immersive simulation comprising potential safety hazards intentionally embedded into a virtual job site; users are required to identify these hazards within a specified time frame with the expectation that they will be more adept at recognizing hazards on an actual job-site, resulting in fewer accidents. This research study seeks to identify the actual impacts of VR on construction safety awareness among participants. The research addresses the following question: Does VR improve hazard recognition awareness? The primary objective is to evaluate participants' performance of past construction safety awareness against present construction safety awareness after receiving VR training. Participants were asked to complete a multiple-choice Qualtrics™ questionnaire. The results of the study showed a statistically significant knowledge gain advantage with respect to hazard recognition and construction safety awareness with the use of interactive, immersive VR over a more conventional and passive safety training method.

• Journal of Korean Traditional Oncology
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• v.28 no.1
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• pp.25-31
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• 2023

Objectives: With antibiotic resistance one of the biggest threats to global health, we report a case of surgical site infection (SSI) after breast cancer surgery that improved only with the treatment of Taglisodog-eum (托裏消毒飮), Korean herbal medicine, without the use of antibiotics. Methods: The patient diagnosed with ductal carcinoma in situ of left breast underwent nipple areola skin sparing mastectomy and reconstruction using deep inferior epigastric perforator flap. About a month later, superficial SSI occurred at the incision site of breast cancer surgery with general weakness, and Taglisodog-eum treatment was started. To evaluate the effectiveness of the treatment, we compared the infection site conditions before and after treatment. Results: About three weeks after taking Taglisodog-eum, the SSI improved along with the improvement of general weakness. Conclusions: This study shows that Taglisodog-eum may be effective for SSI after breast cancer surgery, and the potential for alternatives to reduce antibiotic use and antibiotic resistance.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2023.11a
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• pp.235-236
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• 2023

The process of construction site supervision plays a crucial role in ensuring safety and quality assurance in construction projects. However, traditional methods of supervision largely depend on human vision and individual experience, posing limitations in quickly detecting and preventing all defects. In particular, the thorough supervision of expansive sites is time-consuming and makes it challenging to identify all defects. This study proposes a new construction supervision system that utilizes vision processing technology and Artificial Intelligence(AI) to automatically detect and analyze defects as a solution to these issues. The system we developed is provided in the form of an application that operates on portable devices, designed to a lower technical barrier so that even non-experts can easily aid construction site supervision. The developed system swiftly and accurately identifies various potential defects at the construction site. As such, the introduction of this system is expected to significantly enhance the speed and accuracy of the construction supervision process.

• Journal of Periodontal and Implant Science
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• v.28 no.1
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• pp.87-102
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• 1998

The purpose of this stuffy was to assess and compare the osseous responses to implanted particles of porous synthetic HA (Interpore $200^{(R)}$, Interpore International, U.S.A.), resorbable natural bovine derived HA (Bio-$oss^{(R)}$, Gestlich Pharma, Switzerland) and calcium carbonate(Biocoral $450^{(R)}$, Inoteb, France) in bone defects. Four calvarial defects of 2.5mm diameter were created in earth of 16 Sprague-Dawley rats. The experimental materials were subsequently implanted hi three defects, leaving the fourth defect for control purpose. Four animals were earth sacrificed at 3 days, 1week, 2weeks and 4 weeks after surgery. The tissue response was evaluated under light microscope. Overall, histologic responses showed that all the particles were well tolerated and caused no aberrent tissue responses. There were difference in the amount of newly formed bone at the experimental sites and control site. There was more new bone formation associated with calcium carbonate site. In addition, the calcium carbonate site displayed multinucleated giant cells surrounding calcium carbonate particles after the 1st week, and osteoid tissue within the particle after the 2nd week. After 4 weeks, calcium carbonate particles were resorbed and replaced with new bone. The healing of the natural bovine derived HA site was similar to that of porous synthetic HA, except that new bone growth between the two particles have progressed more in the former site after the 2nd week. In the natural bovine derived HA site, the particle was surrounded by newly formed bone after the 4th week. After 4 weeks, the control site showed more mature bone than other sites. In conclusion, the grafted site were better in new bone formation than non-grafted sites. In particular the calcium Carbonate site showed the ability of osteoinduction and natural bovine denver HA showed osteoconduction in rat calvarial defects. This suggest that calcium carbonate and natural bovine derived HA could enhance the regenerative potential in periodontal defects.

• BMB Reports
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• v.54 no.3
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• pp.176-181
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• 2021

Bcl-x, a member of the Bcl-2 family, plays a key role in apoptosis. Alternative splicing of Bcl-x pre-mRNA through alternative 5' splice-site selection produces an anti-apoptotic mRNA isoform that includes exon 2b and a pro-apoptotic Bcl-x mRNA isoform that excludes exon 2b. Here we used Bcl-x minigene and identified SRSF2 and SRSF6 as two regulatory factors of 5' splice-site selection of Bcl-x pre-mRNA. We selected binding clusters closer to 5' splice-sites from multiple potential binding sites of SRSF2 and SRSF6 to perform loss of functions analysis through site-directed mutagenesis. Our results demonstrated that these mutations did not abolish regulatory functions of SRSF2 or SRSF6, indicating that a single binding motif or a cluster was not a functional target of these proteins in Bcl-x pre-mRNA splicing. Random deletion mutagenesis did not disrupt the role of SRSF2 and SRSF6. Importantly, mutagenesis of 5' splice-site to a conserved or a weaker score demonstrated that the weaker strength of the target 5' splice-site or higher strength of the other 5' splice-site strength limited the role of SRSF2 and SRSF6 in 5' splice-site activation.