• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2006년도 정기 학술대회 논문집
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• pp.473-480
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• 2006

Liquefaction of soil foundation is one of the major seismic damage types of infrastructures. In this paper, deterministic and probabilistic approaches for the evaluation of liquefaction potential are briefly summarized and the risk assessment method is newly proposed using seismic fragility and seismic hazard curves. Currently the deterministic approach is widely used to evaluate the liquefaction potential in Korea. However, the there are a certain degree of uncertainties in the soil properties such as elastic modulus and resistant capacity, therefore the probabilistic approach is more promising. Two types of probabilistic approach are introduced including (1) failure probability for a given design earthquake and (2) the seismic risk of liquefaction of soil for a given service life. The results from different methods show a similar trend, and the liquefaction potential can be more quantitatively evaluated using risk analysis method.

• Safety and Health at Work
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• 제8권2호
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• pp.143-150
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• 2017

A huge number of chemicals are produced and used in the world, and some of them can have negative effects on the reproductive health of workers. To date, most chemicals and work environments have not been studied for their potential to have damaging effects on the workers' reproductive system. Because of the lack of information, many workers may not be aware that such problems can be related to occupational exposures. Newly industrialized countries such as Republic of Korea have rapidly amassed chemicals and other toxicants that pose health hazards, especially to the reproductive systems of workers. This literature review provides an overview of peer-reviewed literature regarding the teratogenic impact and need for safe handling of chemicals. Literature searches were performed using PubMed, Google Scholar, and ScienceDirect. Search strategies were narrowed based on author expertise and 100 articles were chosen for detailed analysis. A total of 47 articles met prespecified inclusion criteria. The majority of papers contained studies that were descriptive in nature with respect to the Medical Subject Headings (MeSH) terms and keywords: "reproductive and heath or hazard and/or workplace or workers or occupations." In the absence of complete information about the safe occupational handling of chemicals in Republic of Korea (other than a material safety data sheet), this review serves as a valuable reference for identifying and remedying potential gaps in relevant regulations. The review also proposes other public health actions including hazard surveillance and primary prevention activities such as reduction, substitution, ventilation, as well as protective equipment.

• 한국산업보건학회지
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• 제10권1호
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• pp.147-159
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• 2000

The NIOSH health hazard evaluation program (HHE program) was created in response to the mandate to determine the toxic effect and potential health hazard of workplace exposure, which is found in Occupational Safety and Health Act of 1970 and the Federal Mine Safety and Health Act of 1977, A primary benefit of HHE program is its ability to provide current health hazard data to employers and employees, which assists them in identifying solutions to occupational health and safety problems in their workplaces, The HHE program also stimulates research in the development and review of sampling methods and diagnostic tests and may prompt additional exposure assesment efforts and toxicological and epidemiological studies. HHE projects also provide human exposure-toxicity data that are used to asses the validity of existing occupational health standards and to support criteria for new standards of recommendation, The HHE request is classified into four categories: 1) category 1: As a administratively invalid, 2) category 2: These are valid requests for which a site visit is not essential to an appropriate response, 3) Category 3 : These are valid requests for which a site visit is necessary for an adequate evaluation, 4) These are valid request which present a complex problem or an opportunity for research, To carry out HHE program one or methods of investigation might be used: 1) direct observation and evaluation of production processes and employee work practices 2) employees exposure level and air contamination level 3) medical test or physical examinations of employees 4) private, confidential interviews with employees 5) review of employer's record of injuries and illness, employee exposure data, medical tests and job histories. After investigation and analysing the data, NIOSH issues a final report, giving finding and recommendation.

• 한국화재소방학회논문지
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• 제14권4호
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• pp.7-16
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• 2000

본 연구에서는 대상물질을 선점한 후 그에 따른 세 가지 기준 즉 독성, 화재폭발, 환경기준과 각각의 피해예측기법을 설정하고 이 기준들을 알고리즘을 통한 통합한 종합위해등급으로서 선정된 대상물질에 적용하였다. 특히, 환경기준은 포괄적인 개념으로서 USCG 및 MSDS의 환경기준 분류와 NFPA의 건강위해성(Nh) 중 환경관련 부분을 조합하여 환경지수 모델화를 하였다. 또한 각 기준에 따른 피해예측 기법을 선택하여 지역별 인의에 위치한 화학물질 관련업체에 사용 또는 저장 중인 유해화학물질에 대해 적용하여 사용물질에 대한 종합위해등급 설정(단일물질에 대한 가연성, 독성, 반응성, 환경성에 대한 Hazard level 및 표시 모델화) 및 그에 따른 사고시 피해예측 강도산정 (CPQRA, IAEA, VZ eq), Risk contour를 구할 수 있었다. 이 결과 모든 화학공정 및 저장 등에서 발생할 수 있는 독성 누출, 화재폭발의 잠재적 위험성산정을 통한 안전성 평가의 Tool로 활용이 가능하다.

• Earthquakes and Structures
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• 제15권1호
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• pp.67-79
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• 2018

Malaysia and Singapore have adopted Eurocode 8 (EC8) for the seismic design of building structures. The authors studied the seismic hazard modelling of the region surrounding Malaysia and Singapore for a long time and have been key contributors to the drafting of the Malaysia National Annex (NA). The purpose of this paper is to explain the principles underlying the derivation of the elastic response spectrum model for Malaysia (Peninsular Malaysia, Sarawak and Sabah). The current EC8 NA for Singapore is primarily intended to address the distant hazards from Sumatra and is not intended to provide coverage for potential local intraplate hazards. Hence, this paper recommends a reconciled elastic response spectrum for Singapore, aiming to achieve a more robust level of safety. The topics covered include the modelling of distant interplate earthquakes generated offshore and local earthquakes in an intraplate tectonic setting, decisions on zoning, modelling of earthquake recurrences, ground motion and response spectrum. Alternative expression for response spectrum on rock, strictly based on the rigid framework of EC8 is discussed.

• 한국식품위생안전성학회:학술대회논문집
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• 한국식품위생안전성학회 1992년도 학술강연회
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• pp.33-45
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• 1992

The sanitation inspection is the most frequently used procedure to protect foods prepared in foodservice establishments. In order to enhance foodservioe inspections and to improve post-inspection remedial measures, more practical evaluation methods for sanitation are required. The HACCP approach is based upon factors which contribute to foodborne disease rather than on factors which relate to aesthetics. Contributing factors for foodborne disease from foodservice establishments reported in USA, Canada, and England were analyzed to identify potential hazards during practical foodservioe operations. Hazards were classified at critical control points by risk ranking. Twenty-two observable practical indicators relating to each contributing factor were selected and adjusted to standardized procedures and hazard determiners at critical contral points. The weights for each inspection item were ranked as 1, 2, 3, 4 or 5 according to the risk level of contributing factors. And also application for the inspection item in different 6 types of work procedures was suggested for the use of specialized foodservice establishment and cafeteria, and of manager's self inspection in each establishment.

• Smart Structures and Systems
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• 제6권4호
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• pp.405-421
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• 2010

This paper proposes a method for early warning of hazard for pipelines. Many pipelines transport dangerous contents so that any damage incurred might lead to catastrophic consequences. However, most of these damages are usually a result of surrounding third-party activities, mainly the constructions. In order to prevent accidents and disasters, detection of potential hazards from third-party activities is indispensable. This paper focuses on recognizing the running of construction machines because they indicate the activity of the constructions. Acoustic information is applied for the recognition and a novel pipeline monitoring approach is proposed. Principal Component Analysis (PCA) is applied. The obtained Eigenvalues are regarded as the special signature and thus used for building feature vectors. One-class Support Vector Machine (SVM) is used for the classifier. The denoising ability of PCA can make it robust to noise interference, while the powerful classifying ability of SVM can provide good recognition results. Some related issues such as standardization are also studied and discussed. On-site experiments are conducted and results prove the effectiveness of the proposed early warning method. Thus the possible hazards can be prevented and the integrity of pipelines can be ensured.

• Safety and Health at Work
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• 제6권3호
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• pp.184-191
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• 2015

Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial. To clarify the mutagenicity of allyl chloride and because a micronucleus (MN) test had not yet been conducted, we screened for MN induction by using male ICR mice bone marrow cells. The test results indicated that this chemical is not mutagenic under the test conditions. In this paper, the regulatory test battery and several assay combinations used to determine the genotoxic potential of chemicals in the workplace have been described. Further application of these assays may prove useful in future development strategies of hazard evaluations of industrial chemicals. This study also should help to improve the testing of this chemical by commonly used mutagenicity testing methods and investigations on the underlying mechanisms and could be applicable for workers' health.

• Advances in environmental research
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• 제5권2호
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• pp.79-94
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• 2016

In order to evaluate the contamination and health risk, levels of six hazardous elements i.e., Cr, Ni, Cu, As, Cd and Pb in soils of 12 different land-uses were measured. The average concentration of Cu, Cr, Ni, Pb, As and Cd in soils were 267, 239, 206, 195, 58 and 16 mg/kg, respectively. Levels of each metal exceeded the environmental action level for soils, which could pose significant risk to human. The metal concentrations were subsequently used to establish hazard indices (for adults and children) where the 5th and 95th percentile values were used to derive the hazard index through different exposure pathways (ingestion, dermal contact and inhalation). Considering the total exposure through each of the three pathways, the hazard index elucidates that there was a potency of non-cancer risk at most of the sites for both the adults and children. The findings of this study suggested that different land-use soils were severely contaminated with hazardous elements and attention is needed on the potential health risks to the exposed inhabitants.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2003-2007
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• 2012

Purpose: E-cadherin is a transmemberane protein which is responsible for adhesion of endothelial cells. The aim of our study was to assess existing evidence of associations between reduced expression of E-cadherin and prognosis of ovarian cancer with a discussion of potential approaches to exploiting any prognostic value for improved clinical management. Methods: We conducted a meta-analysis of 9 studies (n=915 patients) focusing on the correlation of reduced expression of E-cadherin with overall survival. Data were synthesized with random or fixed effect hazard ratios. Results: The studies were categorized by author/year, number of patients, FIGO stage, histology, cutoff value for E-cadherin positivity, and methods of hazard rations (HR) estimation, HR and its 95% confidence interval (CI). Combined hazard ratios suggested that reduced expression of E-cadherin positivity was associated with poor overall survival (OS), HR= 2.10, 95% CI:1.13-3.06. Conclusion: The overall survival of the E-cadherin negative group with ovarian cancer was significant poorer than the E-cadherin positive group. Upregulation of E-cadherin is an attractive therapeutic approach that could exert significant effects on clinical outcome of ovarian cancer.