• Title/Summary/Keyword: potential ability

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Apoptosis in Cancer - An Update

  • Sankari, S. Leena;Masthan, K.M.K.;Babu, N. Aravindha;Bhattacharjee, Tathagata;Elumalai, M.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.4873-4878
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    • 2012
  • Apoptosis is programmed cell death which is essential for development and survival of living organisms. It is a sequentially regulated suicidal programme where cells activate certain enzymes which dissolute their own nuclear component and various protein component of nucleus and cytoplasm. Disturbance of this regulatory pathway may lead to various diseases like autoimmune diseases, neurodegenerative diseases and cancers. The potential mechanisms of apoptosis and its role in cancer are discussed. The ability of apoptosis to modulate the life or death of a cell is also recognized for its immense therapeutic potential. Understanding the mechanisms from this review will give us better insight to the pathogenesis of various diseases including cancer and will open new horizons to therapeutic approaches.

Study on Surge Voltage Distribution Design for UHV Transformer Windings by Finite Element Method (유한요소법에 의한 초고압변압기권선의 충격파전위분포설계에 관한 연구)

  • 황영문;이일천
    • 전기의세계
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    • v.28 no.11
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    • pp.45-51
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    • 1979
  • Finte element methods are developed for the initial distribution problems which contain the surge potential circuits of high voltage transformer windings. The initial distribution of surge voltages in transformer windings are useful to the work to a practical engineering basis. However, the conventional methods of analyzing them so far are much complicated for practical designs. In this paper, the ability to solve surge potential field problems underlies the development of descreting methods to a lodal capacitive distribution-coefficients for determing the surge voltage relationship among a set of transformer coils. A practical example-the modeling of an antioscillation shield coil winding and hisercap winding is used to illustrate and evaluate these methods.

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THE EFFECT OF GENISTEIN CONCENTRATED POLYSACCHARIDE (GCP) SUPPLEMENTATION ON OXIDATIVE DNA DAMAGE AND PLASMA TOTAL ANTIOXIDANT POTENTIAL IN OLD FEMALE SPRAGUE-DAWLEY RATS.

  • Park, Eunju;Shin, Jang-In;Park, Ok-Jin;Kang, Myung-Hee
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.118-119
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    • 2001
  • The anti-cardiovascular effect of estrogen replacement therapy in postmenopausal women is known to be associated with its role as an antioxidant, its ability to protect cells from DNA damage. Genistein concentrated polysaccharide (GCP) is a functional food produced by fermentation of soybean isoflavone extracts with Basidiomycetes, containing rich content of genistein aglycones. The aim of this study was to investigate the effect of GCP on oxidative DNA damage and plasma total antioxidant potential, comparing to the effect of estrogen.(omitted)

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A Study on the Initial Stage of Extensive Reading Process through College Students' Journal Writing

  • Heo, Sunyoung
    • English Language & Literature Teaching
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    • v.18 no.3
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    • pp.77-92
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    • 2012
  • This paper explores the learners' experience process and features in the initial stage of extensive reading process through college students' daily based journal writings. The subjects of this study were 10 volunteer students and they kept their journals from 30 minutes to 2 hours daily based for two weeks. The participants took pre and post tests in order to find out how their reading comprehension ability improved. Four of them improved it while the rest of them did not. After writing journals for two weeks, all students agreed on the potential power of extensive reading. In addition, they realized their learning problems and tried to overcome them on their own ways. Although the research period was only two weeks, the students showed the potential of extensive reading in learning English. From the results of the study, extensive reading encouraged the students to read more and they were convinced that extensive reading will lead to successful learning English. It can be meaningful outcome from the 2-week period research. Thus, a longer period scheme could provide more detail information to the extensive reading.

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Peroxiredoxins and the Regulation of Cell Death

  • Hampton, Mark B.;O'Connor, Karina M.
    • Molecules and Cells
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    • v.39 no.1
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    • pp.72-76
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    • 2016
  • Cell death pathways such as apoptosis can be activated in response to oxidative stress, enabling the disposal of damaged cells. In contrast, controlled intracellular redox events are proposed to be a significant event during apoptosis signaling, regardless of the initiating stimulus. In this scenario oxidants act as second messengers, mediating the post-translational modification of specific regulatory proteins. The exact mechanism of this signaling is unclear, but increased understanding offers the potential to promote or inhibit apoptosis through modulating the redox environment of cells. Peroxiredoxins are thiol peroxidases that remove hydroperoxides, and are also emerging as important players in cellular redox signaling. This review discusses the potential role of peroxiredoxins in the regulation of apoptosis, and also their ability to act as biomarkers of redox changes during the initiation and progression of cell death.

Temporal Variation of the Western Pacific Subtropical High Westward Ridge and its Implicationson South Korean Precipitation in Late Summer

  • Ahn, Kuk-Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2019.05a
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    • pp.24-24
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    • 2019
  • This study investigates variations in the Western Pacific Subtropical High (WPSH) and its impact on South Korean precipitation in late summer during the period between 1958 and 2017. Composite analysis reveals that precipitation occurrence is directly linked to the displacement of the WPSH western ridge, a single, large-scale feature of the atmosphere in the Pacific Ocean. When WPSH ridging is located northwest (NW) of its climatological mean position, excessive precipitation is expected in late summer due to enhanced moisture transport. On the other hand, a precipitation deficit is frequently observed when the western ridge is located in the southeast (SE). Different phases of the WPSH are associated with lagged patterns of Pacific and Atlantic atmospheric and oceanic variability, introducing the potential to predict variability in the WPSH western ridge and its climate over northern East Asia by one month. Based on the identified SST patterns, a simple statistical model is developed and improvement in the ability to predict is confirmed through a cross-validation framework. Finally, the potential for further improvements in WPSH-based predictions is addressed.

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Remediation capabilities of pilot-scale wetlands planted with Typha aungstifolia and Acorus calamus to treat landfill leachate

  • Bhagwat, Rohit V.;Boralkar, Dilip B.;Chavhan, Ram D.
    • Journal of Ecology and Environment
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    • v.42 no.4
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    • pp.191-198
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    • 2018
  • Improper management and unsanitary approaches are implemented in disposal of leachate, which has resulted in groundwater pollution at village Uruli Devachi, Pune, India. Various physico-chemical treatment methods are commercially available for leachate treatment. However, the application of biological methods viz. phytoremediation to the municipal solid waste landfill leachate has been limited. We report the remediation ability of Typha aungstifolia and Acrorus calamus that is capable of reducing hazardous constituents from the landfill leachate. After 96 h of hydraulic retention time (HRT), it was observed that T. aungstifolia-treated sample showed high reduction potential in reducing biochemical oxygen demand, chemical oxygen demand, hardness, total dissolved solids, Na, Mg, Ca and Ni whereas A. calamus showed greater reduction capacity for alkalinity, Cl, Cu, Zn and Cr. Furthermore, it was also observed that T. aungstifolia withstood longer HRT than A. calamus. In situ application of T. aungstifolia and A. calamus for remediation of landfill leachate carries a tremendous potential that needs to be further explored.

Management of Innovations and Projects in the System of Improving the Performance of Personnel as a Factor in Ensuring the Competitiveness and Investment Security of the Enterprise

  • Kopytko, Marta;Nikolchuk, Yulia;Urba, Svitlana;Darmits, Rostyslav
    • International Journal of Computer Science & Network Security
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    • v.22 no.10
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    • pp.201-206
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    • 2022
  • The main purpose of the study is to analyze the features of innovation and project management in the system of improving the performance of personnel as a factor in ensuring competitiveness and investment security. For the successful operation of enterprises, regardless of their form of ownership and field of activity, in order to carry out effective activities, they turn to innovative methods related to the formation of the potential of the workforce, and increasing the level of education and qualifications of staff and establishing their potential ability to make independent decisions. Based on the results of the study, the key features of innovation and project management in the system of improving the performance of personnel as a factor in ensuring competitiveness and investment security are characterized.

Recent advances in water and wastewater treatment using membranes with carbon nanotubes

  • Michal, Bodzek;Krystyna, Konieczny;Anna, Kwiecinska-Mydlak
    • Membrane and Water Treatment
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    • v.13 no.6
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    • pp.259-290
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    • 2022
  • Carbon nanotubes (CNTs), due to their excellent physical, chemical and mechanical properties and their ability to prepare new membranes with attractive properties, have found applications in water and wastewater technology. CNT functionalization, which involves the introduction of different types of functional groups into pure CNTs, improves the capabilities of CNT membranes for water and wastewater treatment. It turns out that CNT-based membranes have many advantages, including enhanced water permeability, high selectivity and anti-fouling properties. However, their full-scale application is still limited by their high cost. With their tremendous separation efficiency, low biofouling potential and ultra-high water flux, CNT membranes have the potential to be a leading technology in water treatment in the future, especially in desalination.

Bacterial endophytes from ginseng and their biotechnological application

  • Chu, Luan Luong;Bae, Hanhong
    • Journal of Ginseng Research
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    • v.46 no.1
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    • pp.1-10
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    • 2022
  • Ginseng has been well-known as a medicinal plant for thousands of years. Bacterial endophytes ubiquitously colonize the inside tissues of ginseng without any disease symptoms. The identification of bacterial endophytes is conducted through either the internal transcribed spacer region combined with ribosomal sequences or metagenomics. Bacterial endophyte communities differ in their diversity and composition profile, depending on the geographical location, cultivation condition, and tissue, age, and species of ginseng. Bacterial endophytes have a significant effect on the growth of ginseng through indole-3-acetic acid (IAA) and siderophore production, phosphate solubilization, and nitrogen fixation. Moreover, bacterial endophytes can protect ginseng by acting as biocontrol agents. Interestingly, bacterial endophytes isolated from Panax species have the potential to produce ginsenosides and bioactive metabolites, which can be used in the production of food and medicine. The ability of bacterial endophytes to transform major ginsenosides into minor ginsenosides using β-glucosidase is gaining increasing attention as a promising biotechnology. Recently, metabolic engineering has accelerated the possibilities for potential applications of bacterial endophytes in producing beneficial secondary metabolites.