THE EFFECT OF GENISTEIN CONCENTRATED POLYSACCHARIDE (GCP) SUPPLEMENTATION ON OXIDATIVE DNA DAMAGE AND PLASMA TOTAL ANTIOXIDANT POTENTIAL IN OLD FEMALE SPRAGUE-DAWLEY RATS.

  • Park, Eunju (Dept. Food and Nutrition, Division of Life Science, Kyungnam University) ;
  • Shin, Jang-In (Dept. Food and Nutrition, Hannam University) ;
  • Park, Ok-Jin (Dept. Food and Nutrition, Hannam University) ;
  • Kang, Myung-Hee (Dept. Food and Nutrition, Hannam University)
  • Published : 2001.10.01

Abstract

The anti-cardiovascular effect of estrogen replacement therapy in postmenopausal women is known to be associated with its role as an antioxidant, its ability to protect cells from DNA damage. Genistein concentrated polysaccharide (GCP) is a functional food produced by fermentation of soybean isoflavone extracts with Basidiomycetes, containing rich content of genistein aglycones. The aim of this study was to investigate the effect of GCP on oxidative DNA damage and plasma total antioxidant potential, comparing to the effect of estrogen.(omitted)

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