• 대한환경공학회지
• /
• 제37권11호
• /
• pp.597-606
• /
• 2015

KOH가 용해된 메탄올 및 에탄올 용액의 탄산화를 통해 Potassium methyl carbonate (PMC) 및 Potassium ethyl carbonate (PEC) 침전물을 합성하여 $CO_2$를 고정화하고 침전물의 특성 연구를 수행하였다. PMC 및 PEC는 $CO_2$의 화학 흡수 반응에 의해 고체 침전물로 합성되고 이를 위해 소비된 $CO_2$양은 각 이론 값의 97.90% 및 99.58%이며 탄산화 중 상당량의 물리 흡수도 일어난다. 합성된 침전물은 PMC 및 PEC와 $KHCO_3$의 중량 비율이 약 5:5 및 8:2인 혼합물이며 침전물들은 물에 용해되어 알코올이 재생되고 최종 $KHCO_3$가 회수됨에 따라 본 공정은 효율적인 하나의 CCS 또는 CCU 기술로 활용될 가능성이 있다.

• 자원리싸이클링
• /
• 제25권3호
• /
• pp.43-48
• /
• 2016

시멘트 공장에서는 폐기물 재활용 측면에서 다양한 산업부산물 및 생활폐기물을 사용한다. 이들 폐기물에는 다량의 칼륨과 염소 및 소량의 중금속 등도 함유되어 있으며, 이들 성분을 유가자원으로 활용하기 위한 다양한 시도가 이루어지고 있다. 본 연구에서는 칼륨과 염소를 용해 결정화하여 염화칼륨을 수득하기 위한 다양한 방안을 검토하였다. 특히 혼합수 함량, 슬러리 온도 및 교반시간 등을 제어하였다. 또한 수득 염화칼륨 중에 존재하는 중금속 종류 함량 등도 분석하였다. 염화칼륨 수득량은 혼합수 함량 증가에 따라 증가하였으나, 1 : 2 (더스트:혼합수) 이상에서는 소폭 증가하였다. 슬러리 온도에 따른 수득량은 일정온도 이상에서 증가하는 경향을 나타내었으며, 교반시간 10분 이상에서는 수득량 변화가 관찰되지 않았다. 교반시간 증가에 따라 수득된 염화칼륨의 중금속 종류 함량도 다양하였으며, 주요 중금속은 Pb, Cu 및 $Cr^{6+}$ 등으로 확인되었다.

• Clinical and Experimental Pediatrics
• /
• 제57권10호
• /
• pp.445-450
• /
• 2014

Purpose: Familial hypokalemic periodic paralysis (HOKPP) is an autosomal dominant channelopathy characterized by episodic attacks of muscle weakness and hypokalemia. Mutations in the calcium channel gene, CACNA1S, or the sodium channel gene, SCN4A, have been found to be responsible for HOKPP; however, the mechanism that causes hypokalemia remains to be determined. The aim of this study was to improve the understanding of this mechanism by investigating the expression of calcium-activated potassium ($K_{Ca}$) channel genes in HOKPP patients. Methods: We measured the intracellular calcium concentration with fura-2-acetoxymethyl ester in skeletal muscle cells of HOKPP patients and healthy individuals. We examined the mRNA and protein expression of KCa channel genes (KCNMA1, KCNN1, KCNN2, KCNN3, and KCNN4) in both cell types. Results: Patient cells exhibited higher cytosolic calcium levels than normal cells. Quantitative reverse transcription polymerase chain reaction analysis showed that the mRNA levels of the $K_{Ca}$ channel genes did not significantly differ between patient and normal cells. However, western blot analysis showed that protein levels of the KCNMA1 gene, which encodes $K_{Ca}$1.1 channels (also called big potassium channels), were significantly lower in the membrane fraction and higher in the cytosolic fraction of patient cells than normal cells. When patient cells were exposed to 50 mM potassium buffer, which was used to induce depolarization, the altered subcellular distribution of BK channels remained unchanged. Conclusion: These findings suggest a novel mechanism for the development of hypokalemia and paralysis in HOKPP and demonstrate a connection between disease-associated mutations in calcium/sodium channels and pathogenic changes in nonmutant potassium channels.

• Journal of Korean Neurosurgical Society
• /
• 제38권5호
• /
• pp.375-379
• /
• 2005

Objective : Papaverine has been used in treating vasospasm following subarachnoid hemorrhage[SAH]. However, its action mechanism for cerebral vascular relaxation is not clear. Potassium channels are closely related to the contraction and relaxation of cerebral smooth muscle. Therefore, to identify the role of potassium and calcium channels in papaverine-induced vascular relaxation, we examine the effect of papaverine on potassium channels in freshly isolated smooth muscle cells from rat basilar artery. Methods : The isolation of rat basilar smooth muscle cells was performed by special techniques. The whole cell currents were recorded by whole cell patch clamp technique in freshly isolated smooth muscle cells from rat basilar artery. Papaverine was added to the bath solution. Results : Papaverine of $100{\mu}M$ into bath solution increased the amplitude of the outward $K^+$ current which was completely blocked by BKCa[large conductance calcium dependent potassium channels]blocker, IBX[iberiotoxin], and calcium chealator, BAPTA[l,2-bis[o-aminophenoxy]ethane-N,N,N',N'-tetraacetic acid], in whole cell mode. Conclusion : These results strongly suggest that potassium channels may play roles in papaverine-induced vascular relaxation in rat basilar artery.

• Journal of Korean Neurosurgical Society
• /
• 제57권3호
• /
• pp.197-203
• /
• 2015

Objective : The potassium disturbance associated with thiopental continuous infusion in neurosurgical patients is well known. However, the effect of propofol continuous infusion on serum potassium levels has not been investigated extensively. Methods : We reviewed the medical records of 60 consecutive patients who received coma therapy or deep sedation for intracranial pressure control using either thiopental or propofol between January 2010 and January 2012. Results : The overall incidence of hypokalemia (K<3.5 mmol/L) was comparable between thiopental and propofol groups (89.2% vs. 82.6%). But, the incidence of moderate to severe hypokalemia (K<3.0 mmol/L) was significantly higher in thiopental group (51.4% vs. 13.0%, p=0.003). The lowest potassium level (2.9 mmol/L vs. 3.2 mmol/L, p=0.020) was lower in thiopental group. The patients in the thiopental group required greater potassium replacement than the propofol group patients (0.08 mmol/kg/h vs. 0.02 mmol/kg/h, p<0.001). On multivariate analysis, thiopental [odds ratio, 95% confidence interval, 7.31 (1.78-27.81); p=0.005] was associated with moderate to severe hypokalemia during continuous infusion. The incidence of rebound hyperkalemia (K>5.0 mmol/L, 32.4% vs. 4.3%, p=0.010) and the peak potassium concentration (4.8 mmol/L vs. 4.2 mmol/L, p=0.037) after the cessation of therapy were higher in thiopental group. On multivariate analysis, thiopental [8.82 (1.00-77.81); p=0.049] and duration of continuous infusion [1.02 (1.00-1.04); p=0.016] were associated with rebound hyperkalemia once therapy was discontinued. Conclusion : Propofol was less frequently associated with moderate to severe hypokalemia after induction and rebound hyperkalemia following the cessation of continuous infusion than thiopental.

• 한국토양비료학회지
• /
• 제36권6호
• /
• pp.399-406
• /
• 2003

배추와 무 직파재배시 토양중 치환성 칼륨의 생육 저해 한계 농도를 밝히기 위하여 $1m^2$ 무저 pot에서 주로 농가에서 사용하는 염화칼리비료를 처리하여 토양의 치환성 칼륨행동과 작물의 생육과 발아특성을 조사하여 다음과 같은 결과를 얻었다. 배추와 무의 최고 수량은 토양내 치환성 칼륨 함량이 각각 $0.96cmol_c\;kg^{-1}$, $1.28cmol_c\;kg^{-1}$에서 있었으며, 이때의 염화칼리 비료의 시용량은 봄 배추 $370(K_2O:\;222)\;kg\;ha^{-1}$, 가을 무 $517(K_2O:\;310)\;kg\;ha^{-1}$이었다. 이 이상에서는 토양의 치환성 칼륨함량이 높아짐에 따라 수량은 낮아지는 경향을 보였다. 토양의 치환성 칼륨 함량과 작물의 발아율과의 관계를 보면 배추는 치환성 칼륨 함량이 $0.54cmol_c\;kg^{-1}$이하에서는 정상적인 발아가 되었으나 $1.29cmol_c\;kg^{-1}$은 83%, $2.30cmol_c\;kg^{-1}$은 67%의 발아율을 보였고, 무의 경우에는 $1.29cmol_c\;kg^{-1}$ 이하에서는 정상적 생육, $2.30cmol_c\;kg^{-1}$에서는 83%의 발아율을 보였다. 발아장해를 받는 토양의 전기전도도 값은 배추는 $1.29dS\;m^{-1}$, 무는 $2.30dS\;m^{-1}$이었다. 따라서 작물 재배전에 다량의 염화칼리비료 시용은 전기전도도의 증가로 염류장해를 받을 우려가 있기 때문에 이를 고려하여 시비관리를 해야할 필요가 있는 것으로 판단되었다.

• 아시안잔디학회지
• /
• 제26권2호
• /
• pp.116-122
• /
• 2012

본 연구는 규산과 칼리 시용이 골프장 그린용 크리핑 벤트그래스 잔디의 생육과 품질 그리고 내답압성에 미치는 영향을 알아보기 위해 실시되었다. 먼저 규산과 칼리 시용에 따른 잔디반응을 살펴보기 위해서 필드조건에서 잔디품질, 뿌리길이, 잔디밀도와 건물중을 평가하였다. 다음으로 답압빈도에 따른 크리핑 벤트그래스의 잔디생육(뿌리길이, 잔디밀도, 건물중)과 잔디품질 및 토양경도를 조사하였다. 마지막으로 30일간의 답압처리조건에서 규산과 칼리의 내답압성 시비효과를 평가하였다. 규산 및 칼리 처리에 따른 잔디뿌리생육에 있어서 규산을 증가함에 따라 뿌리길이가 증가하였다. 크리핑 벤트그래스의 답압빈도에 따른 잔디품질은 1일 2회 처리구가 가장 우수하였으며, 7회 처리구는 무답압 처리구보다 우수하였다. 그러나 15회 이상 답압 처리구는 잔디품질이 월등히 저하하였다. 30일간의 답압처리시 규산 및 황산칼리의 시비효과는 잔디품질 향상 및 뿌리생육 증진효과가 있었다. 규산과 칼리를 처리하였을 때 잔디품질이 대조구보다 각각 6.38%, 10.25% 상승하였으며 규산과 칼리를 혼용 살포하였을 때 가장 잔디품질이 좋았다. 잔디 뿌리길이는 규산을 살포하였을 때 가장 길었으며 대조구보다 11.4%가 길었다. 따라서 답압이 예상되는 골프장 그린용 벤트그래스에서 잔디의 내답압성 증진을 위해서는 규산과 칼리의 시비가 효과적이었다.

• 환경생물
• /
• 제30권4호
• /
• pp.314-318
• /
• 2012

The aims of the present study were to estimate the possibility for toxicity test and compare acute toxicity of potassium dichromate in the larva stage of Neocaridina denticulata, Daphnia magna and the juvenile stage of Oryzias latipes. N. denticulate, a freshwater shrimp lives in Korea, is an indigenous species and considered to be useful for toxicity test. D. magna and O. latipes were recommended as a test species for the OECD test guideline. The 96 h-$LC_{50}$ potassium dichromate value was 0.62 mg $L^{-1}$ for the larva stage of N. denticulata and 168.44 mg $L^{-1}$ for the juvenile stage of O. latipes. The 48 h-$EC_{50}$ value was 1.27 mg $L^{-1}$ for the D. magna. The study was confirmed higher sensitivity of the larva stage of N. denticulata to potassium dichromate compared to the D. magna and the juvenile stage of O. latipes.

• Archives of Pharmacal Research
• /
• 제24권3호
• /
• pp.240-248
• /
• 2001

The present study was attempted to investigate the effect of quinine on secretion of catecholamines (CA) etroked by cholinergic stimulation and membrane depolarization from the isolated perfused rat adrenal gland. The perfusion of quinine (15-150${\mu}$M) into an adrenal vein for 60 min produced dose- and time-dependent inhibition in CA secretion evoked by ACh ($5.32{\times}10^{-3}M$), high $K^{+}5.6{\times}10^{-2}M$, DMPP ($10^{-4}M$ for 2 min), McN-A-343 ($10^{-4}M$ for 2 min), cyclopiazonic acid ($10^{-5}$ for 4 min) and Bay-K-8644 ($10^{-5}$ M for 4 min). Also, under the presence of pinacidil ($10^{-4}$ M), which is also known to be a selective potassium channel activator, CA secretory responses evoked by ACh, high potassium, DMPP McN-A-343, Bay-K-8644 and cyclopiazonic acid were also greatly reduced. When preloaded along with quinine ($5{\times}10^{-5}M$) and glibenclamide ($10^{-6}$ M), a specific blocker of ATP-regulated potassium channels, CA secretory responses evoked by ACh, high potassium, DMPP McN-A-343, Bay-K-8644 and cyclopiazonic acid were recovered as compared to those of quinine-treatment only. taken together, these results demonstrate that quinine inhibits CA secretion evoked by stimulation of cholinergic (both nicotinic and muscarinic) receptors as well as by membrane depolarization through inhibiting influx of extracellular calcium and release in intracellular calcium in the rat adrenmodullary chromaffin cells. These findings suggest that activation of potassium channels may be involved at least in inhibitory action of quinine on CA secretion from the rat adrenal gland.

• Preventive Nutrition and Food Science
• /
• 제17권2호
• /
• pp.93-100
• /
• 2012

The purpose of this study was to identify food sources for major minerals such as calcium (Ca), phosphorus (P), sodium (Na) and potassium (K), and to evaluate the relationship between dietary intake of these minerals and serum lipids in healthy Korean adults. A total of 132 healthy men and women completed a physical examination and dietary record and provided blood samples for lipid profile analysis. Results showed the following daily average mineral intakes: 373.4 mg of calcium, 806.0 mg of phosphorous, 3685.8 mg of sodium, and 1938.3 mg of potassium. The calcium-to-phosphorus and sodium-to-potassium ratio was about 0.5 and 2.0, respectively. The primary sources for each mineral were: vegetables (24.9%) and fishes (19.0%) for calcium, grains (31.4%) for phosphorus, seasonings (41.6%) and vegetables (27.0%) for sodium, and vegetables (30.6%) and grains (18.5%) for potassium. The correlation analysis, which has been adjusted for age, gender, total food consumption, and energy intake, showed significantly positive correlations between Ca/P and serum HDL cholesterol levels, between Na intake and the level of serum total cholesterol, and between Na/K and the level of serum cholesterol and LDL cholesterol. Our data indicates that the level of mineral consumption partially contributes to serum lipid profiles and that a diet consisting of a low Ca/P ratio and a high Na/K ratio may have negative impacts on lipid metabolism.