• Journal of Ginseng Research
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• 제33권2호
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• pp.89-92
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• 2009

Ginseng is a popular herbal medicine that has been used for thousands of years. A number of its components have been isolated and characterized, including ginsenosides, polysaccharides, peptides, polyacetylenic alcohols, and fatty acids. The lipophilic characteristics of ginsenosides have raised the possibility of their efficacy as steroid hormones. Several in-vitro studies have reported their pharmacological function as steroid hormones, especially estrogen, but no human study to date has confirmed their efficacy as alternatives to synthetic estrogen.

• 대한지역사회영양학회지
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• 제12권1호
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• pp.25-39
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• 2007

The purpose of this study was to investigate the dietary intakes in middle-aged women(pre and postmenopausal) and relation to climacteric symptoms. We conducted the anthropometric measurements, climacteric symptoms survey, and dietary intake to assess the nutrient intakes. Also, dietary quality indices were evaluated. The subjects, over 40 years old, were 168 middle aged women(pre=74, postmenopausal=94), mean age was $48.9{\pm}3.6yr$. The anthropometric measurements showed that 59% of subjects were overweight and obese. Climacteric symptoms that were answered 'yes' in 50% plus in the subjects, were dry eyes, forgetfulness, difficult concentration, large joint pain(shoulder), fatique, backache, dry skin, joint pain(ankle and knee), dry mouth, dizziness, depression and lonesomeness, snore, morning stiffness, and hot flash. Some symptoms showed significant difference between pre and postmenopausal groups. The average energy intake was 1602.1 Kcal, which was 82% of the Korean EER. The subjects had lower vitamin A, riboflavin, folic acid, Fe, Zn and Ca intake than Korean RI. The lowest nutrient intake was Ca. The mean of food intake was 1294.2 g and MAR of diet quality indices was 0.83. In relation to dietary factors with climacteric symptoms, significant correlations have been found between total protein, animal protein, lipid, cholesterol and niacin intake and 'fatique', energy, carbohydrate, thiamin, vitamin B6, folic acid, vitamin C, Na, K and Fe intake and 'dry skin', Ca intake and 'difficult concentration'. Our results indicate that dietary factors(food and nutrients intake, INQ, NAR, MAR) may effect the prevention and reduction of some climacteric symptoms in middle aged women.

• 대한한방부인과학회지
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• 제36권4호
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• pp.61-77
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• 2023

Objectives: This study aimed to identify the current use and investigate the clinical practice of Korean Medicine for climacteric syndrome and postmenopausal syndrome outpatients. Methods: We studied climactic syndrome and postmenopausal syndrome outpatients who visited Daejeon Korean Medicine Hospital of Daejeon University from January 1, 2019 to December 31, 2021 via an analysis of the medical records. Results: 130 patients were finally selected. Their average age was 51.91±4.57 years and the average number of visits was 7.51±11.40 times. Patients usually complained two or more addresses, and the most frequent symptoms were hot flushes. 126 patients took herbal medicines and 99 of them took herbal decoctions. 106 patients were treated by acupuncture. 58 patients were treated by pharmacopuncture and Hominis Placenta was used to 50 subjects. As for the improvement rate by symptoms, hot flushes were the highest at 65.5%. We compared the improvement rate of groups taking Guibi-tang-gami A and Guibi-tang-gami B, the common herbal decoction of Daejeon Korean Medicine Hospital of Daejeon University. In the group of Guibi-tang-gami A, the improvement rate of hot flushes was the highest and in the other, vaginal dryness was the highest. Urinary frequency of the group with Hominis Placenta pharmacopuncture showed more than three times higher improvement rate of the non-executive group. Conclusions: We analyzed general characteristics, clinical characteristics, types of Korean medicine treatment, improvement rates by symptoms of 130 outpatients diagnosed with climactic syndrome and postmenopausal syndrome. This study could be used as reference to provide practical data of outpatient treatment for Climacteric Syndrome and Postmenopausal Syndrome.

• 정신신체의학
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• 제4권1호
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• pp.98-108
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• 1996

Korean women are now living almost 1/3 of their life after menopause. Sex-steroid hormone deficiency adversely affect various fields of physical & mental activity and quality of life during this period. Therefore, replacement of deficient hormone is thought to be natural therapeutic modality. Postmenopausal syndrome is recently redefined as an endocrinopathy with both short-and long-term sequelae, as a result of cessation of ovarian function. Hormone replacement therapy taken at or near time of menopause alleviates shot-term acute menopausal symptoms such as vasomotor disturbances and psychological problems. HRT also beneficially affects some of intermediate symptoms such as urogenital atrophy and cutaneous problems. The major benefits of long-term use were reductions in risk of long-term sequelae, that is, total fracture by 50-60%, cardiovascular disease by 50% and cerebrovascular disease by 30-40%, respectively. In addition, HRT may also positively influence Alzheimer's disease, reduce the colorectal cancer risk and increase longevity of the life. In conclusion, all postmenopausal women should consider preventive HRT when there are no contraindications.

• 대한간호학회지
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• 제33권4호
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• pp.471-477
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• 2003

Purpose. This cross-sectional survey research was undertaken to examine the degree of depression in post-menopausal women and to analyze the factors affecting that depression. Method. 325 people from public health center in Inchon were surveyed as the subject of this study. Data collection was conducted through the use of questionnaires. Results. The above half of these sampled people were in depressed state (64.0%) and the mean score of depression was 12.71. There were significant differences in the depression state according to presence of spouse, economic level, exercise, and smoking. A positive correlation was found between depression and climacteric symptoms. Stepwise multiple regression analysis revealed that the most powerful predictor was climacteric symptom. Climacteric symptom, presence of spouse, smoking, and exercise accounted for 45 % of the variance in postmenopausal women's depression. Conclusion. Nurses are able to use these results to plan and implement nursing interventions for decreasing depression and consequent the improved quality of life in Korean postmenopausal women. Also, the nurses have to be more aware of the following groups; solitary women, low-income group and smokers, that they have higher mean score of depression.

• 동아시아식생활학회지
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• 제14권3호
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• pp.233-242
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• 2004

The purpose of this study was to investigated the possibility of Meles meles as an edible functional resource. To assess the effects of Meles meles fermented liquid(ML) with medicinal plants in postmenopausal women, the menopause symptoms, hematological and serum chemical variables and bone health indices were examined. Twenty five postmenopausal women participated in the study. As a result, in postmenopausal women, ML supplements were effective in reducing the incidence of menopause symptoms, such as insomnia(44.0%), sensitivity(40.0%), headache(34.0%), hot flush and decreased vaginal lubrication(20.0%) after 12 weeks. Also serum estradiol and calcitonin and calcium levels were 23.27 pg/mL, 14.88 pg/mL and 8.86 mg/dL before the ML intake. Levels were significantly increased of estradiol and calcitonin and calcium after ML intake during 12 weeks to 30.36 pg/mL, 21.61 pg/mL and 10.01 mg/dL. Osteocalcin and bone alkaline phosphatase activity were 14.36 ng/mL, 21.55 U/L before the ML intake, but according to ML intake, the levels were significantly decreased. In conclusion, ML play benefical roles in the prevention of bone loss and menopause symptoms. Howere current data are not sufficient to determine the effective doses for benefical effect as well as harmful effect and support dietary recommendation level for ML. Therefore, our results should be viewed with caution. But Meles meles fermented liquid with medicinal plants can be used as possible food resources and functional food materials, more studies are needed to identify the proper mechanism of ML.

• 대한한방부인과학회지
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• 제36권1호
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• pp.90-102
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• 2023

Objectives: The purpose of this study is to report the clinical effectiveness of Korean medicine treatment on postmenopausal syndrome. Methods: The patient with postmenopausal syndrome with palpitation was treated with Korean medicine treatment during 14 days of hospitalization. The patient received Korean medicine treatment including herbal medicine, acupuncture and moxibustion. The effect of treatment on postmenopausal syndrome was evaluated through the Numeric Rating Scale (NRS) and questionnaire. Palpitation and arrhythmia was evaluated by Electrocardiogram (ECG) and manual pulse diagnosis three times a day. Result: After the treatment, the clinical postmenopausal symptoms of palpitation and hot flush were improved. Also, ECG's result was improved ventricular premature contraction to normal ECG. Conclusions: This case report proved that the Korean medicine treatment may be effective for improving postmenopausal syndrome with palpitation and hot flush. However, further clinical study is needed in the future to prove the effectiveness of Korean medicine treatment for postmenopausal syndrome with palpitation and hot flush.

• Journal of Nutrition and Health
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• 제39권2호
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• pp.121-132
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• 2006

Minerals are extremely important in human metabolism, growth, and tissue repair. The risks of disturbances in mineral nutrition and metabolism are high following menopause. The aim of the study was to investigate the mineal nutrition status in middle-aged women (Pre & Postmenopausal) and the relation to climacteric symptoms. In the present study, we conducted the anthropometric measurement, climacteric symptoms survey and the dietary intakes including macronutrients, vitamins and minerals to assess the nutrient intakes. Also plasma mineral levels (Ca, P, Mg, Na, K, Fe, Cu, Zn) was measured. The participants were 105 middle-aged women (pre=51, Postmenopausal=54). The anthropometric measurement showed that 74% of subjects was overweight and obesity. The energy intakes were 83% of Korean EER. The macromineral intake (Ca, P, Mg, Na, K), Ca, P and Mg were 65%, > 116% and > 107% of Korean RI. Na and K intakes were > 243% and 53% of Korean AI. For the trace mineral intake (Fe, Cu, Zn), Fe, Cu and Zn intakes were 82%, > 146%, and 94% of Korean RI. The serum mineral concentration measurement, in case of Ca, Fe and Zn, > 10% of subjects showed lower level than normal clinical range. The most frequently appeared climacteric symptoms were dry eye, forgetfulness, difficult concentration, shoulder pain, fatique, depression & lonesomeness, backache, snore, dry skin, ankle & knee pain. In relation to mineral nutrition with climacteric symptoms, significant correlations have been founded between Ca intake and difficult concentration, Mg intake and snore, Fe & Zn intake and forgetfulness & dry skin, serum Ca concentration and forgetfulness, serum Na concentration and dry eyes & snore, serum K concentration and shoulder pain. From these results, it has been indicated that some mineral nutrition status may effect the prevention and reduction of climacteric symptoms in pre and postmenopause women.

• 한방안이비인후피부과학회지
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• 제30권4호
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• pp.176-183
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• 2017

Objectives : The purpose of this study is to report the effect of Hwangryunhaedoktang-Gamibang on Postmenopausal Hot Flushes. Methods : This case study was done on 3 Postmenopausal Hot Flush patients who have visited Korean Medicine Clinic. Hwangryunhaedoktang-Gamibang was prescribed to all 3 patients and evaluated the symptom change through photographs and questionnaire. Investigator's Global Assessment(IGA) was used to evaluate the objective symptom and Visual Analogue Scale(VAS) was used to evaluate the subjective change. Results & Conclusions : The IGA and VAS were decreased in all patients. Most symptoms of 3 patients were improved. As a result of examining IGA, VAS scores and photographs, Hwangryunhaedoktang-Gamibang can be effective on Postmenopausal hot flush.

• 대한간호학회지
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• 제45권1호
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• pp.25-34
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• 2015

Purpose: This study was conducted to examine effects of a cardiocerebrovascular disease (CVD) prevention education program on knowledge, self-efficacy and health behavior among postmenopausal middle-aged women. Methods: A non-equivalent control group pretest-posttest design was used. Participants were 53 postmenopausal middle-aged women who registered in two community culture centers in G metropolitan city. Experimental group (n=26) received a CVD prevention education program 8 times over 8 weeks. Knowledge, self-efficacy and health behavior of the participants were examined with self-report structured questionaries. Data were collected between October 15 and December 11, 2013, and were analyzed using chi-square test, Fisher's exact test, independent t-test, and analysis of covariance with SPSS/PC version 21.0. Results: After the intervention the experimental group showed significant increases in the knowledge of CVD symptoms (p<.001) and CVD risk factors (p<.001), level of self-efficacy (p=.028) and health behavior (p<.001) compared to the control group. However, no significant difference was found between groups for knowledge of CVD prevention (p<.133). Conclusion: Results suggest that a CVD prevention education program can be an effective strategy to improve knowledge on CVD symptoms and risk factors, self-efficacy and health behavior for postmenopausal middle-aged women.