Relation of Mineral Nutrition Status and Climacteric Symptoms in Pre- and Postmenopausal Women

폐경기를 전.후한 중년 여성의 무기질영양상태와 갱년기증상

  • Kim Soon-Kyung (Department of Food Science and Nutrition, Soonchunhyang University) ;
  • SunWoo Jae-Gun (Department of Obstetrics and Gynecology, Soochunhyang University) ;
  • Lee Eun-Ju (Department of Food Science and Nutrition, Soonchunhyang University)
  • 김순경 (순천향대학교 자연과학대학 식품영양학과) ;
  • 선우재근 (순천향대학교 의과대학 산부인과교실) ;
  • 이은주 (순천향대학교 자연과학대학 식품영양학과)
  • Published : 2006.03.01

Abstract

Minerals are extremely important in human metabolism, growth, and tissue repair. The risks of disturbances in mineral nutrition and metabolism are high following menopause. The aim of the study was to investigate the mineal nutrition status in middle-aged women (Pre & Postmenopausal) and the relation to climacteric symptoms. In the present study, we conducted the anthropometric measurement, climacteric symptoms survey and the dietary intakes including macronutrients, vitamins and minerals to assess the nutrient intakes. Also plasma mineral levels (Ca, P, Mg, Na, K, Fe, Cu, Zn) was measured. The participants were 105 middle-aged women (pre=51, Postmenopausal=54). The anthropometric measurement showed that 74% of subjects was overweight and obesity. The energy intakes were 83% of Korean EER. The macromineral intake (Ca, P, Mg, Na, K), Ca, P and Mg were 65%, > 116% and > 107% of Korean RI. Na and K intakes were > 243% and 53% of Korean AI. For the trace mineral intake (Fe, Cu, Zn), Fe, Cu and Zn intakes were 82%, > 146%, and 94% of Korean RI. The serum mineral concentration measurement, in case of Ca, Fe and Zn, > 10% of subjects showed lower level than normal clinical range. The most frequently appeared climacteric symptoms were dry eye, forgetfulness, difficult concentration, shoulder pain, fatique, depression & lonesomeness, backache, snore, dry skin, ankle & knee pain. In relation to mineral nutrition with climacteric symptoms, significant correlations have been founded between Ca intake and difficult concentration, Mg intake and snore, Fe & Zn intake and forgetfulness & dry skin, serum Ca concentration and forgetfulness, serum Na concentration and dry eyes & snore, serum K concentration and shoulder pain. From these results, it has been indicated that some mineral nutrition status may effect the prevention and reduction of climacteric symptoms in pre and postmenopause women.

Keywords

References

  1. Lee JH, Chung YK, Park HM, Park JS, Yumiko H, Yeoum SG. A study on Climacteric symptoms in Korean Midlife women. J Korean Soc Menopause 6(2): 142-156, 2000
  2. Kim BN, Lee JS, Lee KS, Song BG. Clinical study of the Climacteric syndromes. J Oriental Gynecology 11(1): 23-29, 1998
  3. Melissa KM. Factor analysis of climacteric syptomes in Japan. Maturitas(52): 205-222, 2005
  4. Han IK, Park KO, Kim HM, Cho NH. Climacteruc syptomes and perception in middle aged Korean women. J Korean Soc Menopause 4(1): 3-15, 1998
  5. Lee JH, Yeoum SG. Climacteric women's life style and acceptance about menopause. J Korean Soc Menopause 9(3): 254-260, 2003
  6. Feldman BM, Voda A, Gronseth E. The prevalence of hot flush and associated variables among perimenopausal women. Res Nurs Health 8: 261-274, 1985 https://doi.org/10.1002/nur.4770080308
  7. Yeoum SG. The investigation on the risk factors of cardiovascular disease for postmenopausal women over 50 years. J Korean Soc Menopause 9(3): 266-272, 2003
  8. Korea national statistical office. Annual report on the vital statistics, 2002
  9. Seo MS. Woman's health problem in Ministry of gender equality & family. Korean J Health Promot Dis Pre 2(1): 115-118, 2002
  10. Moon SJ. An ecological study of the health status and dietary habits of korean women in menopause. J Korean Home Economics Association 26(1): 83-96, 1988
  11. Lee YI. Health menagement of climacterics women. J Korean Acad Farm Med 16(3): 252-257, 1995
  12. Drewnowski A, Henderson SA, Shore AB. Diet quality and dietary diversity in France: Implications for the French paradox. J Am Diet Assoc 96: 663-669, 1996 https://doi.org/10.1016/S0002-8223(96)00185-X
  13. Lee SY, Ju DL, Paik HY, Shin CS, Lee HK. Assessment of dietary intake obtained by 24-hour recall method in adults living in Yeonchon area (I) : Assessment based on nutrient intake. Korean J Nutr 31(3): 333-342, 1998
  14. Lee SY, Ju DL, Paik HY, Shin CS, Lee HK. Assessment of dietary intake obtained by 24-recall method in adults living in Yeonchon area (2): Assessment based on food group intake. Korean J Nutr 31(3): 343-353, 1998
  15. Chang HK, Han YB. A study on the climacteric symptoms and dietary patterns in middle aged women. J Korean Home Economics Association 40(1): 125-134, 2002
  16. Montilla RN, Marucci MF, Aldrighi JM. Nutritional status and food intake assessment of climacterics women. Rev Assoc Med Bras 49(1): 91-95, 2003 https://doi.org/10.1590/S0104-42302003000100040
  17. Bureau I, Anderson RA, Arnaud J, Raysiguier Y, Favier AE, Roussel AM. Trace mineral status in post menopausal women: impact of hormone replacement theraphy. J Trace Elem Med Biol 16(1): 9-13, 2002 https://doi.org/10.1016/S0946-672X(02)80003-7
  18. Meram I, Balat O, Tamer L, Ugur MG. Trace elements and vitamin levels in menopausal women receiving hormone replacement theraphy. Clin Exp Obstet Gynecol 30(1): 32-34
  19. Food Composition Table. 6th revision, National Rural Living Science Institute, 2001
  20. Souci SW, Fachmann W, Kraut H. Food composition and nutrition tables. CRC press, 1994
  21. Yoo MS. A comparative study on complaints of menopausal symptom of nuns and marries women. J Korean Soc Nursing Sci 30(1): 18-28, 2000 https://doi.org/10.4040/jkan.2000.30.1.18
  22. Eva C, Janet B. Symptom experience in Australian men and women in midlife. Maturitas 44: 225-236, 2003 https://doi.org/10.1016/S0378-5122(03)00037-9
  23. Korean Nutrition Society. Dietary reference intakes for Koreans, 2005
  24. http://inews.mk.co.kr/CMS/include/template
  25. Yeo E. Menopause, Aging and Obesity. J Korean Soc Study Obesity 11(3): 289-298, 2002
  26. Yoon YS. Obesity in Women: Pregnancy and Menopause. J Korean Acad Farm Med 23(5): 553-563, 2002
  27. Wing RR, Mattews KA, Kuller LH. Weight gain at the time of menopause. Arch Intern Med 151(1): 97-102, 1991 https://doi.org/10.1001/archinte.151.1.97
  28. Harbo J, Marslew U, Gotfedson A, Christiansen C. Postmenopausal hormone replacement theraphy prevents central distribution of body fat after menopause. Metabolism 40: 1323-1326, 1991 https://doi.org/10.1016/0026-0495(91)90037-W
  29. Lee JY. Climacteric endocrinology. J Korean Menopause, 8th science meeting, ss23-24, 1997
  30. Pochlman ET, Goran MI, Gardner AW. Metaboilc determinnents of decline in resting metabolic rate in aging females. Am J Physiol 264: 450-455, 1993
  31. Ju HO, Seo JM, Hwang JH, Park HS, Lee EN, Hwang SK. Comparative study on climacteric symptoms, knowledge of menopause and menopausal menagement of middle aged women between urban and rural areas. Korean J Women Health Nurs 11(1): 27-37, 2005
  32. Sung CJ, Baek SK, Lee HS, Kim MH, Choi SH, Lee SY, Lee DH. A study of body anthropometry and dietary factors affecting bone mineral density in Korean pre and postmenopausal women. J Korean Soc Food Sci Nutr 30(1): 159-167, 2001
  33. Sung CJ, Choi YH, Kim MH, Choi SH, Cho KO. Astudy of nutrient intake and serum levels of osteocalcium, Ca, P and Mg and their correlation to bone mineral density in Korean postmenopausal women residing in rural areas. Korean J Community Nutrition 7(1): 111-120, 2002
  34. Choi YS, Kwak IS, Lee JA, Lee SY. Annual changes in cholesterol intake and serum cholesterol level of Korean from 1961 to 1995 year. J Korean Soc Food Sci Nutr 28(2): 484-491
  35. Shim JE, Kim JH, Nam GY, Paik HY, Moon HK, Kim YO. Comparative analysis and evaluation of dietary intakes of Koreans by age groups: (3) Risk factors for chronic degenerative diseases. Korean J Nutr 35(1): 78-89, 2002
  36. Ministry of Health and Welfare. 2001 National Health and Nutritional Survey Reports in Korea, 2002
  37. Kim MH, Sung CJ. A comparative study mineral intake status and serum mineral concentrations of postmenipausal vegeterian women with those of the the omnivores. Korean J Nutr 38(2): 151-160, 2005
  38. Andon MB, Smith KT, Bracker M, Sartoris D, Saltmam P, Strause L. Spinal bone density and Ca intake in healthy postmenopausal women. Am J Clin Nutr 54: 927-929, 1991 https://doi.org/10.1093/ajcn/54.5.927
  39. Avioli LV. Calcium and Phosphorus. In Shils ME, Young VR, et al, Modern Nutrition in health and disease 7th ed, Lea & Febiger, pp.142-158, 1988
  40. Calvo MS. Dietary phosphorus, calcium metabolism and bone. J Nutr 123: 1627-1633, 1993
  41. Andeson JJB, Ira W, Dorothy KT. Diet and osteoporosis. Nutritional concers of women. CRC Press, 1996
  42. Karaja NM, Obarzanek E, Lin PH, McCullough ML, Phillips KM, Swain JF, Champagne CM, Hoben KP. Descriptive characteristics of dietary patterns used in Dietary the dietary approaches to stop hypertension trial. J Am Diet Assoc 99: 19S-27S, 1999
  43. Wylie RJ. Trial of antihypertensive intervention and management: great efficacy with weight reduction than with a sodium-potassium intervention. J Am Diet Assoc 93: 408, 1993
  44. Monsen ER. Iron nutrition and absorption: Dietary factors which impact iron bioavailability. J Am Diet Assoc 88(7): 786-790, 1988
  45. Baynes RD, Bothwell TH. Iron deficiency. Annu Rev Nutr 10: 133-149, 1990 https://doi.org/10.1146/annurev.nu.10.070190.001025
  46. Tietz MW. Fundamentals of clinical chemistry 3rd ed. Saunders, 1987
  47. Gibson RS. content and bioavailability of trace elements in vegeterian diets. Am J Clin Nutr 59(5S): 1223S-1232S, 1994
  48. OH SY. Micronutrient intake and growth of Korean children. J Korean Diet Assoc 5: 231-237, 1999
  49. Konig D, Weinstock C, Keul J, Northoff H, Berg A. Zinc, iron and magnesium status in athletes-influence on the regulation of exercise-induced stress and immune function. Exerc Immunol Rev 4: 2-21, 1998
  50. Mahan LK, Sylvia ES. Kraus's Food, Nutrition, & Diet Theraphy, Chapter 5, 11th ed. Saunders, 2004
  51. Duvovsky SL, Christiano J, Daniell LC, Frank RD. Increased palatet intracellular calcium concentration in patients with bipolar affective disorders. Arch Gen Psychiatry 46: 632-638, 1989 https://doi.org/10.1001/archpsyc.1989.01810070058010
  52. Guesry P. The role of nutrition in brain development. Prev Med 27(2): 189-194, 1998 https://doi.org/10.1006/pmed.1998.0292
  53. Institute of Medicine. Dietary Reference Intakes, National Academy Press, pp.442-489, 2001
  54. Park KS, Kim HJ, Han JS. The relationship of serum Ca and Mg levels to depression and anxiety symptoms in homemakers. Korean J Nutr 31(1): 102-107, 1998